Transgenic animals ppt
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Transgenic animals are produced by inserting foreign genes into their genomes using recombinant DNA methodology. This allows for increased growth, improved disease resistance, and other benefits. However, it can also lead to unintended effects if the inserted gene has multiple functions or causes mutations. Common methods to create transgenic animals include embryonic stem cell methods, pronuclear injection, and retrovirus-mediated gene transfer. Examples include transgenic mice, cows, fish, sheep, and monkeys that are used for various purposes like producing human proteins, studying diseases, and reducing animal testing in medical research.
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![TRANSGENIC ANIMALS ,[object Object],[object Object],[object Object],[object Object],[object Object],By: M.V.Prasanth M.Pharm Pharmacology](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
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In laboratory animal field , the anesthetic surgeon and post operative are often one and the same person.
This will help to chose correct drug for anaesthesia.
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The anesthetic agents are great and choosing the correct one for particular suggestion.
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This will help to chose correct drug for anaesthesia.
Sometime the wise anesthetic agents also cause undesirable responses. so, its responsibility of experimenters to document this advance in exprimental protocol
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This document discusses various methods for evaluating anti-asthmatic drugs, including both in vitro and in vivo methods. It provides details on common animal models and techniques used. Some key points:
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- Popular in vivo models include measuring bronchospasm in guinea pigs and studying effects on histamine-induced bronchoconstriction, arachidonic acid responses,
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genetically modified organisms
Genetically modified organisms (GMOs) are organisms whose genetic material has been altered using genetic engineering techniques. Common GMOs include crop plants and microbes. The genetic material is typically transferred between different species, which would not occur naturally. This allows for precise and fast introduction of traits compared to traditional breeding methods. While GMOs hold promise for increasing crop yields and producing medicines, there are also health and environmental safety concerns that require further research.
production of transgenic animals .pptx
Transgenic animals are created by inserting foreign DNA into the animal's genome using recombinant DNA technology. The first transgenic animal was a mouse created in 1974. Common animals used for transgenics include mice, pigs, cows, and goats. The foreign DNA is constructed with a gene, vector, and regulatory sequences and inserted into fertilized eggs or embryonic stem cells. Transgenic animals are screened for the inserted gene and used to study gene functions, create disease models, and produce therapeutic products. They have applications in medicine, agriculture, and industry. Issues include potential health and environmental risks of transgenic organisms.
production of transgenic animals. pptx
Transgenic animals are created by inserting foreign DNA into the animal's genome using recombinant DNA technology. The first transgenic animal was a mouse created in 1974. Common animals used for transgenics include mice, pigs, cows, and fish. The foreign DNA is constructed with a gene, vector, and regulatory sequences and inserted into fertilized eggs or embryonic stem cells. Transgenic animals are useful for studying gene functions, developing disease models, and producing therapeutic products. Issues include potential health and environmental risks. Recent research has produced bioluminescent mouse models and transgenic goats engineered to produce human breast milk components. Transgenic technology holds promise but requires responsible research and oversight.
Transgenic animals
1. A transgenic animal is one that has had a foreign gene deliberately inserted into its genome. The first transgenic animal was a "Supermouse" created in 1982 by inserting a human growth hormone gene.
2. There are three main steps to creating a transgenic animal: construction of the transgene, introduction of the gene into the animal, and screening progeny for integration of the gene. Methods like pronuclear microinjection and embryonic stem cell manipulation are used.
3. Transgenic animals have applications in medicine, agriculture, and industry. They are used as disease models, to produce pharmaceuticals, for improved food production, and to test chemicals.
MBB611 Transgenic animals
Transgenic animals are animals that have been genetically modified to carry foreign genes inserted into their genome. This document discusses the production of transgenic animals, their applications in medicine, agriculture and industry, as well as issues related to their use. Transgenic animals are produced using techniques like pronuclear microinjection, retrovirus-mediated gene transfer, and embryonic stem cell-mediated gene transfer. They can be used for research, increasing agricultural yields, producing pharmaceuticals, and testing chemicals. However, there are also biosafety, ethical and environmental issues to consider with transgenic animals. With proper research and regulation, transgenic animals could help address problems that currently lack solutions.
Transgenic animals by Ashish
Transgenic animals are created by inserting foreign genes into the animal's genome. The first transgenic animal was a "Supermouse" created in 1982. There are several methods to produce transgenic animals, including pronuclear microinjection, embryonic stem cell methods, sperm-mediated transgenesis, and somatic cell nuclear transfer. Transgenic animals have applications in medicine, agriculture, and industry. However, there are also some ethical and environmental concerns regarding transgenic technology.
Transgenic animals and process to make transgenic animals
The document summarizes topics related to transgenic animals and gene therapy. It discusses transgenic cows, sheep, poultry, and fish. For each animal, it describes the process used to create transgenic versions, including pronuclear microinjection and somatic cell nuclear transfer. Benefits include producing human therapeutic proteins and altering milk composition. Challenges include high costs and low success rates. Gene therapy techniques like viral vectors and electroporation are explained for inserting genes into tissues to treat disease. Somatic gene therapy aims to modify individual patients while germline gene therapy alters heritable genes passed to offspring.
Molecular pharming
This is about methods of creating transgenic animals,applications of transgenic animals in biotechnology and application of transgenic animals in pharmaceuticals.
Transgenic animals
A transgenic animal is one that has had foreign DNA inserted into its genome. The first transgenic animal was a mouse created in 1982 by inserting a human growth hormone gene. Transgenic animals are created through pronuclear microinjection or stem cell methods. They have applications in medicine, agriculture, and industry. However, some argue that transgenic technology raises ethical issues.
Transgenic animals
A transgenic animal is one whose genome has been altered by the transfer of a gene or genes from another species or breed.
presentation on transgenic animals.pptx
This presentation aims to provide an in-depth understanding of the science behind creating transgenic animals, explore their potential applications, and delve into the ethical considerations surrounding this emerging field of research.
Definition and Background:
We begin by defining transgenic animals as organisms that have had their genetic material intentionally altered through the introduction of foreign genes. This groundbreaking field of genetic engineering has its roots in the development of recombinant DNA technology in the 1970s, which enabled the transfer of genes across different species.
Genetic Engineering Techniques:
This section delves into the techniques employed to create transgenic animals, emphasizing the following key methodologies:
a. DNA Microinjection: The introduction of foreign DNA into the pronucleus of a fertilized embryo, allowing the foreign gene to be incorporated into the animal's genome and expressed in its cells.
b. Gene Targeting: The precise modification of an organism's genome by replacing or disrupting specific genes using technologies such as homologous recombination or CRISPR-Cas9.
c. Somatic Cell Nuclear Transfer (SCNT): The cloning technique involving the transfer of a nucleus from a somatic cell into an enucleated egg, resulting in the creation of an embryo with the same genetic makeup as the somatic cell donor.
Applications of Transgenic Animals:
This section explores the wide-ranging applications of transgenic animals across various fields, including:
a. Biomedical Research: Transgenic animals serve as invaluable models for studying human diseases and testing potential therapies, enabling significant advancements in medical research.
b. Agriculture: Transgenic animals can be engineered to possess desirable traits, such as increased resistance to diseases or improved meat quality, offering the potential to enhance agricultural productivity and sustainability.
c. Pharmaceutical Production: Transgenic animals can be designed to produce therapeutic proteins or antibodies in their milk or blood, providing a cost-effective means of manufacturing valuable pharmaceutical products.
d. Organ Transplantation: Research on transgenic animals has explored the possibility of generating organs that are genetically compatible with humans, addressing the shortage of donor organs for transplantation.
Genetic engineering
Transgenesis is the process of introducing an exogenous gene from other species into a living organism so that it exhibits a new property and transmits it to offspring, making them transgenic. There are three main methods - DNA microinjection, retrovirus-mediated gene transfer, and embryonic stem cell-mediated gene transfer. The first involves microinjecting DNA into reproductive cells, the second uses retroviruses to insert genes into host cells, and the third inserts genes into embryonic stem cells then implants them into embryos. Transgenic animals have applications like producing pharmaceuticals in their milk or blood, growing larger for food, or serving as disease models to benefit human health.
TRANSGEIC ANIMALS MICE BIRD.pptx
It's include all the details about the transgenic technology.all the techniques like micro injection,SCNT,pro nuclear injection method.It include all the Transgenic mice bird and fish.
Transgenic animal and their use in drug development.pptx
Transgenic animal study is an important method of modern researches and drug development. Transgenic animal is the genetically modified to contain –
Gene from a different species following gene transplantation or
Due to molecular manipulations of endogenous genomic DNA. Widely accepted tools in agriculture as well as newer drug development
Accessibility of the researches and compensation of shortage of resources
Social and legal controls in these researches
Uses of this technique in case of cancer management.
Transgenic Animals.pptx
Transgenic Animals- Animal in which new or altered gene have been experimentally inserted into their genome by genetic engineering technique.
Transgenic animals
Transgenic animals are produced by artificially introducing genetic material from another species into the animal's genome. There are several methods used to create transgenic animals, including DNA microinjection, retrovirus-mediated gene transfer, and embryonic stem cell transfer. Examples of transgenic animals include mice, cows, pigs, monkeys, rabbits, and fish. Transgenic animals have applications in medicine, agriculture, and industry, such as producing human proteins for pharmaceuticals, creating disease models, and improving crop yields. However, there are also disadvantages like unintended effects on the animal's genes and low survival rates.
transgenic technology.pptx
This document discusses transgenic technology and various transgenic organisms that have been developed. It begins by defining transgenesis as the process of introducing an exogenous or altered gene into an organism so that it exhibits a new property. Various methods for creating transgenic organisms are described, including microinjection, lipofection, and viral transformation. Examples of transgenic applications in medicine, research, industry, and agriculture are provided. Key transgenic animals that have been developed including brainbow mice, spider goats, cancer-resistant mice, and glofish are summarized.
Genetically modified animals
This document provides an overview of genetically modified animals. It begins with an introduction that defines genetically modified animals and notes that most are still in the research stage. It then discusses the process of genetic modification, which involves altering an animal's DNA in a way that does not occur naturally. The document outlines the process of creating genetically modified mammals through gene insertion and screening offspring. It provides examples of genetically modified pigs, cows, goats, mice, sheep, and chickens. The advantages include faster growth, disease resistance, and improved nutrition. Disadvantages include unintended harm, mutations, expense, and complex natural interactions.
Transgenic animals - A brief review
Transgenic animals are animals whose genomes have been altered by the addition of foreign DNA. There are three main methods for creating transgenic animals: retroviral vector method, DNA microinjection, and using engineered embryonic stem cells. Many transgenic animals have been created successfully for various purposes, including glowing zebrafish, faster growing salmon, Alzheimer's disease mouse models, and the first transgenic monkey. Transgenic technology holds promise for applications in agriculture, medicine, and industry, but also raises ethical concerns and biosafety issues.
Transgenic animals which is genetically modified
Transgenic animals are genetically engineered to contain extra genes. They can be created by microinjection of genes into fertilized eggs, transferring genes into embryonic stem cells, or nuclear transfer. Dolly the sheep was the first cloned mammal, created through nuclear transfer. Transgenic animals can produce useful products for humans, like pigs that produce human hemoglobin for transfusions or goats that produce proteins to potentially treat malaria. However, cloning animals is inefficient and risky, with high mortality rates for the offspring.
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Transgenic animals and process to make transgenic animals
Transgenic animals and process to make transgenic animals
Transgenic animal and their use in drug development.pptx
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