The document summarizes key information about the thymus gland: 1. The thymus gland is located in the upper front of the chest behind the sternum and between the lungs. 2. It has a triangular shape and pinkish-gray color, weighing 10-15 grams at birth and growing until puberty. 3. Internally, it is divided into lobules surrounded by septa, with an outer cortex containing thymocytes and an inner medulla containing Hassall's corpuscles.

1. ENDOCRINE SYSTEM
(Thymus gland)
Mr N.JEGAN
Associate Professor
K.M.COLLEGE OF PHARMACY.
MADURAI.

2. Thymus gland-Location
Location:
It is located in the upper front of chest,
directly behind your sternum and between
your lungs.

3. Thymus gland-Structure
 Shape- Triangular in shape.
 Colour- Pinkish-gray
 Weight- 10-15 gm at birth & grows until
puberty.
 It has two lobes.

4. Thymus gland-Structure
 Each lobe is surrounded by a capsule
• It is divided into lobules which are separate
from each by interlobular septum.
• Cortex is the outer portion.
• Medulla is the centre portion

5. Thymus gland- Internal Structure
 Cortex contains a large number of small
densely packed precursors of T
lymphocytes (thymocytes).
 Medulla consists of number of concentric
bodies known as Hassall’s corpuscles.

6. Thymus gland- Hormone
 Secretion of thymus gland collectively
called as
Thymosin
• Derivatives of thymosin hormones
1.Thymulin
2.Thymosin α 1
3.Thymopoietin

7. Thymosin- Functions
 Development and maturation of
T lymphocytes
cell
• T Lymphocyte is the type of white
blood cell that is an essential of
the immune system in our body.

8. Thymosin- Functions

9. Development (Bone marrow) and maturation
(Thymus gland) of T lymphocytes cell

10. Thymus gland- Disease
Myasthenia gravis
(weakness and rapid fatigue
of muscles )
It occurs when the thymus is
abnormally large and produces
antibodies that block or destroy
the muscles' receptor sites.

11.  Pure red cell aplasia
Reduction of red blood cells
(erythrocytes) produced by the bone
marrow
 Hypogammaglobulinemia
Not enough gamma globulins are
produced in the blood.

12. THANKING YOU