Thoracic trauma can result from blunt or penetrating injuries and often involves rib fractures, pneumothorax, hemothorax, or injuries to the heart or lungs. Assessment focuses on life-threatening injuries like tension pneumothorax, massive hemothorax, or pericardial tamponade. Management priorities are airway control, oxygen therapy, needle decompression for tension pneumothorax, chest tube insertion for pneumothorax or hemothorax, and rapid transport to a trauma center.
Hemopneumothorax, or haemopneumothorax is the condition of having air in the chest cavity (pneumothorax) and blood in the chest cavity (hemothorax). A hemothorax, pneumothorax, or the combination of both can occur due to an injury to the lung or chest.
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
Hemopneumothorax, or haemopneumothorax is the condition of having air in the chest cavity (pneumothorax) and blood in the chest cavity (hemothorax). A hemothorax, pneumothorax, or the combination of both can occur due to an injury to the lung or chest.
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
Chest injuries ranks 3rd after head injuries and extremity injuries in a case of multisystem trauma.It is of two types blunt chest trauma and peneterating chest trauma.The main cause of blunt chest trauma is road side accidents due to vehicles. Peneterating chest trauma is more dangerous and is common in war injuries and civilian terroism.In this ppp I have discussed some useful uncommon and important aspects of chest injuries
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
there is the introduction part of the torso trauma,
check out my next ppts for further more about torso trauma.
contents are in following order...
introduction
mechanism of injury
junctional zones of torso
tension pneumothorax
cardiac temponade
massive hemothorax
etc.
check out all slides
Chest injuries ranks 3rd after head injuries and extremity injuries in a case of multisystem trauma.It is of two types blunt chest trauma and peneterating chest trauma.The main cause of blunt chest trauma is road side accidents due to vehicles. Peneterating chest trauma is more dangerous and is common in war injuries and civilian terroism.In this ppp I have discussed some useful uncommon and important aspects of chest injuries
The document consists of the modern day care in case of thoracic. It touches all relevant aspects of the thoracic trauma. Latest recommendations and user friendly interface is the main highlight of this document. One can easily un
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
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TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. .Objectif
After learning you will be know about:
• Anatomy and physiopathology of thoracic
• Identify Common Mechanisms for Thoracic Trauma
• How to examination, assessment and treatment patients with
thoracic trauma
3. Introduction
• 25% of motor vehicle crash deaths are related to thoracic trauma
• Approximately 16,000 deaths annually in US
• Second only to brain and spinal cord injuries as the leading cause of
traumatic death
• Motor vehicle crashes and interpersonal violence are the two main
causes of thoracic trauma
• Most thoracic traumas will also involve the abdominal cavity
5. Mechanism of Thoracic Trauma
• Acceleration and Deceleration forces
• First and second rib fractures can severely injure the pulmonary and cardiac
tissues underneath
• Falls
• Crush Injuries
• Violence
• Motor Vehicle Crashes
6. Pathophysiology of Thoracic Trauma
Blunt Trauma
Results from kinetic energy forces
Subdivision Mechanisms
Blast
-Pressure wave causes tissue disruption
-Tear blood vessels & disrupt alveolar tissue
-Disruption of tracheobronchial tree
-Traumatic diaphragm rupture
Crush (Compression)
-Body is compressed between an object and a hard surface
-Direct injury of chest wall and internal structures
Deceleration
-Body in motion strikes a fixed object
-Blunt trauma to chest wall
-Internal structures
Age Factors
-Pediatric Thorax: More cartilage = Absorbs forces
-Geriatric Thorax: Calcification & osteoporosis = More fractures
7. Pathophysiology of Thoracic Trauma
Penetrating Trauma
Low Energy
-Arrows, knives, handguns
-Injury caused by direct contact and cavitation
High Energy
-Military, hunting rifles & high powered hand guns
-Extensive injury due to high pressure cavitation
-Missile or Shotgun
9. Ribs Fracture
• Most common chest wall injury from direct trauma
• More common in adults than children
• Especially common in elderly
• Ribs form rings
-Possibility of break in two places
• Most commonly 5th - 9th ribs
-Poor protection
• Fractures of 1st and 2nd second require high force
-Frequently have injury to aorta or bronchi
-Occur in 90% of patients with tracheo-bronchial rupture
-May injure subclavian artery/vein
-May result in pneumothorax
• 30% will die
10. Ribs Fracture
• Fractures of 10 to 12th ribs can cause damage to underlying
abdominal solid organs:
• Liver
• Spleen
• Kidneys
11. Ribs Fracture
Assessment Findings
• Localized pain, tenderness
• Increases on palpation or when patient:
• Coughs
• Moves
• Breathes deeply
• “Splinted” Respirations
• Instability in chest wall, Crepitus
• Deformity and discoloration
• Associated pneumothorax or hemothorax
12. Ribs Fracture
Management
• High concentration O2
• Positive pressure ventilation as needed
• Splint using pillow or swathes
• Encourage patient to breath deeply
-Helps prevent atelectasis
• Non-circumferential splinting
• Monitor elderly and COPD patients closely
-Broken ribs can cause decompensation
-Patients will fail to breathe deeply and cough, resulting in poor clearance of
secretions
• Usually Non-Emergent to Transport
13. Flail Chest
Two or more adjacent ribs fractured in two or more places producing a
free floating segment of the chest wall.
Usually secondary to blunt trauma
• Most commonly in MVC
• Also results from
-falls from heights
-industrial accidents
-assault
-birth trauma
More common in older patients
Mortality rates 20-40% due to associated injuries
15. Flail Chest
Assessment Findings
-Chest wall contusion
-Respiratory distress
-Pleuritic chest pain
-Splinting of affected side
-Crepitus
-Tachypnea, Tachycardia
-Paradoxical movement (possible)
16. Flail Chest
Management
• Suspect spinal injuries
• Establish airway
• High concentration oxygen
• Assist ventilation with BVM
-Treat hypoxia from underlying contusion
-Promote full lung expansion
• Mechanically stabilize chest wall
• IV of LR/NS
-Avoid rapid replacement in hemodynamically stable patient
-Contused lung cannot handle fluid load
• Consider need for advanced airway placement
17. Simple Pneumothorax
Pathophysiology
• Air enters pleural space causing partial lung collapse
-small tears self-seal
-larger tears may progress
• Usually well-tolerated in the young & healthy
• Severe compromise can occur in the elderly or patients with
pulmonary disease
• Degree of distress depends on amount and speed of collapse
18. Simple Pneumothorax
Assessment Findings
• Tachypnea, Tachycardia
• Difficulty breathing or respiratory distress
• Pleuritic pain
-may be referred to shoulder or arm on affected side
• Decreased or absent breath sounds
-patients with multiple ribs fractures may splint injured side by
not breathing deeply
19. Simple Pneumothorax
Management
• Establish airway
• High concentration O2 with Non-rebreather mask(NRM)
• Assist with Bag Valve Mask(BVM)
• IV of LR/NS
• Monitor for progression
• Request Advanced Cardiovascular Life Support (ACLS) responsible
• Usually Non-emergent transport
20. Open Pneumothorax
•Hole in chest wall that allows air to enter pleural space.
•The larger the hole, the more likely air will enter there than through
the trachea.
•If the trauma patient does not ventilate well with an open airway,
look for a hole
-May be subtle
-Abrasion with deep punctures
21. Open Pneumothorax
Pathophysiology
• Result of penetrating trauma
• Profound hypoventilation may occur
• Allows communication between pleural space and atmosphere
• Patients development of negative intrapleural pressure
• Results in uni- or bilateral lung collapse
• inability to ventilate affected lung
• Pressure may increase within pleural space
• Leading to hypoxia and hypercarbia
22. Open Pneumothorax
Assessment Findings
• Opening in the chest wall
• Sucking sound on inhalation
• Tachycardia
• Tachypnea
• Respiratory distress
• Subcutaneous Emphysema
• Decreased lung sounds on affected side
23. Open Pneumothorax
Management
-Cover chest opening with occlusive dressing
-High concentration O2
-Assist with positive pressure ventilations prn
-Monitor for progression to tension pneumothorax
-IV with LR/NS
-Emergent Transport
-Trauma Center…
25. Tension Pneumothorax
Pathophysiology
• Air enters pleural space,
but cannot leave(one-way
valve)
-Air is trapped in pleural
space
• Pressure collapses lung on
affected side
• Mediastinal shift to
contralateral side
Reduction in cardiac
output
-Increased intrathoracic
pressure
-deformed vena cava
reducing preload
27. Tension Pneumothorax
• Management
• Recognize early
• Establish airway
• High concentration O2
• Positive pressure ventilations BVM
• Consider need for advanced airway placement
-immediate perform needle to decompression
• IV of LR/NS
Trauma Center preferred.
28. Hemothorax
Pathophysiology
• Blood in the pleural space
• Most common result of major trauma to the chest wall
• Present in 70 - 80% of penetrating and major non-penetrating trauma cases
• Associated with pneumothorax
• Rib fractures are frequent cause
• Life-threatening often requiring chest tube and/or surgery
• If assoc. with great vessel or cardiac injury
-50% die immediately
-25% live five to ten minutes
-25% may live 30 minutes or longer
• Blood loss results in
-Hypovolemia
-Decreased ventilation of affected lung
• Accumulated blood can eventually produce a tension hemothorax
• Shifting the mediastinum producing
30. Diaphragmatic Rupture
• Usually due to blunt trauma but may occur with penetrating trauma
• Usually life-threatening
• Likely to be associated with other severe injuries
31. Diaphragmatic Rupture
Pathophysiology
• Compression to abdomen resulting in increased intra-abdominal
pressure
-abdominal contents rupture through diaphragm into chest
-bowel obstruction and strangulation
-restriction of lung expansion
-mediastinal shift
• 90% occur on left side due to protection of right side by liver
32. Diaphragmatic Rupture
• Assessment Findings
• Decreased breath sounds
-Usually unilateral
-Dullness to percussion
• Dyspnea or Respiratory Distress
• Scaphoid Abdomen (hollow appearance)
• Usually difficult to hear bowel sounds
34. Pericardial Tamponade
• Incidence
-Usually associated with penetrating trauma
-Rare in blunt trauma
-Occurs in < 2% of chest trauma
-GSW wounds have higher mortality than stab wounds
-Lower mortality rate if isolated tamponade
35. Pericardial Tamponade
Pathophysiology
-Space normally filled with 30-50 ml of straw-colored fluid
-lubrication
-lymphatic discharge
-immunologic protection for the heart
-Rapid accumulation of blood in the inelastic pericardium
-Heart is compressed decreasing blood entering heart
.Decreased diastolic expansion and filling
.Hindered venous return (preload)
36. -Myocardial perfusion decreased due to
.pressure effects on walls of heart
.decreased diastolic pressures
-Ischemic dysfunction may result in
injury
-Removal of as little as 20 ml of blood
may drastically improve cardiac output
37. Pericardial Tamponade
Signs and Symptoms
-Beck’s Triad
.Hypotension
.Increased jugular venous pressure
.Diminished heart sounds
-Radial pulse becomes weak or disappears when patient inhales
-Increased intrathoracic pressure on inhalation causes blood to be
trapped in lungs temporarily
38. Pericardial Tamponade
Management
-Augment venous return
-Raise patient’s leg (if possible)
-Rapid IV fluid infusion
-Pericardiocentesis
-If urgent, thoracotomy in OR can be effective
Note: Pericardiocentesis should be considered only if expertise not
available and patient is dying
39. Conclusion
• Key management in thoracic injury include:
-Identifying the life threatening condition
-Resuscitation and oxygen therapy
-Chest tube insertion
-Adequate pain control and aggressive chest physiotherapy
-Ventilation and early associate team