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The Cell
Cycle
Cell follows definite stages of
growth, duplication and division
known as the CELL CYCLE.
This cycle involves distinct and
regular phases of growth and repair
If this cellular cycle goes out of
control, abnormal cell growth can
occur and it can be manifest in the
body of the organism
Stages of Cell Cycle
Interphase
The growth period in the
cell cycle and is divided
in three parts.
Gap 1(G1)
The cell carries out its normal
metabolic functions
Cells also increase their size as
their organelles increase in
number.
Cells spend most of their lives in
this phase, though the length
differ among cell types
Cells have a size limit.
Synthesis (S)
 The time that the cell makes a copy of the genetic
material in the form of nuclear DNA
 The cell spends considerable amount of time and
energy to make copy of its chromosomes
 DNA replication- ensures that the daughter cell
receives exact copies of the parents genetic
material during cell division
 It also produce a copy of protein complex that will
later help the cell organize its content.
 After completion, the cell continues to grow then
prepares for cell division.
Gap 2(G2)
Cell continues to carry out their
normal functions and also
undergo further growth
The cell make sure that
everything is in order(size and
DNA without damage)
Mitosis (M)
Division of the nucleus and the genetic
material
Prophase, Metaphase, Anaphase,
Telophase
The hereditary material of the parent cell is
given to the daughter cell, that leads to the
formation of two daughter cells
The cell nuclear membrane disintegrates,
while DNA condense forming two nuclei
Cytokinesis
Divides the cytoplasm of the
cell
Begins early during telophase
and continues after the nuclei
have formed in the daughter cell
Rates of Cell
division
 Prokaryotic cells have similar structures with
eukaryotic cells but not identical.
 Prokaryotic cells lack membrane bound organelles
and cytoskeleton that make them divide more
rapidly.
 Cell division is faster during embryonic age and
childhood.
 Cell replacement is higher in areas subjected to lot
of wear and tear (skin and intestinal layer)
 Intestinal cells(every few days)
 Intestinal lining, lung, heart, kidney (occasionally.
Injury or cell death)
 Skin cells(after a few weeks)
 Liver cells(when repaiir is needed)
Gap 0 (G0)
Cells are unlikely to divide but still
continue to perform normal function
Neuron cells and heart muscle cells that
are highly differentiated or specialized that
the body cannot easily replace
Neuron(lymphocytes)- remain in the body
until the body recognize an invader
The mechanism of cell
division
Mitosis
 Division of nucleus into genetically
identical nuclei containing the same full
set of DNA
 Prepares the cell for the cytokiniesis
Prophase: start of Mitosis
 1. Chromatin condenses into tightly coiled
chromosomes, that consists of two identical
sister chromatid
 The chromosomes are packaged into neat
bundles for an easy movement when the
division starts
 2. the nuclear envelopes breakdown
 The nucleolus also disappears.
The cell cycle

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The cell cycle

  • 2. Cell follows definite stages of growth, duplication and division known as the CELL CYCLE. This cycle involves distinct and regular phases of growth and repair If this cellular cycle goes out of control, abnormal cell growth can occur and it can be manifest in the body of the organism
  • 4. Interphase The growth period in the cell cycle and is divided in three parts.
  • 5. Gap 1(G1) The cell carries out its normal metabolic functions Cells also increase their size as their organelles increase in number. Cells spend most of their lives in this phase, though the length differ among cell types Cells have a size limit.
  • 6. Synthesis (S)  The time that the cell makes a copy of the genetic material in the form of nuclear DNA  The cell spends considerable amount of time and energy to make copy of its chromosomes  DNA replication- ensures that the daughter cell receives exact copies of the parents genetic material during cell division  It also produce a copy of protein complex that will later help the cell organize its content.  After completion, the cell continues to grow then prepares for cell division.
  • 7. Gap 2(G2) Cell continues to carry out their normal functions and also undergo further growth The cell make sure that everything is in order(size and DNA without damage)
  • 8. Mitosis (M) Division of the nucleus and the genetic material Prophase, Metaphase, Anaphase, Telophase The hereditary material of the parent cell is given to the daughter cell, that leads to the formation of two daughter cells The cell nuclear membrane disintegrates, while DNA condense forming two nuclei
  • 9. Cytokinesis Divides the cytoplasm of the cell Begins early during telophase and continues after the nuclei have formed in the daughter cell
  • 11.  Prokaryotic cells have similar structures with eukaryotic cells but not identical.  Prokaryotic cells lack membrane bound organelles and cytoskeleton that make them divide more rapidly.  Cell division is faster during embryonic age and childhood.  Cell replacement is higher in areas subjected to lot of wear and tear (skin and intestinal layer)  Intestinal cells(every few days)  Intestinal lining, lung, heart, kidney (occasionally. Injury or cell death)  Skin cells(after a few weeks)  Liver cells(when repaiir is needed)
  • 12. Gap 0 (G0) Cells are unlikely to divide but still continue to perform normal function Neuron cells and heart muscle cells that are highly differentiated or specialized that the body cannot easily replace Neuron(lymphocytes)- remain in the body until the body recognize an invader
  • 13. The mechanism of cell division
  • 14. Mitosis  Division of nucleus into genetically identical nuclei containing the same full set of DNA  Prepares the cell for the cytokiniesis
  • 15. Prophase: start of Mitosis  1. Chromatin condenses into tightly coiled chromosomes, that consists of two identical sister chromatid  The chromosomes are packaged into neat bundles for an easy movement when the division starts  2. the nuclear envelopes breakdown  The nucleolus also disappears.