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An artificial heart is a prosthetic device
that is implanted into the body to replace
the biological heart.
Artificial heart a pumping mechanism
that duplicates the rate, output, and blood
pressure of the natural heart; it may
replace the function of a part or all of the
heart.
INTRODUCTION
2
3
ARTIFICIAL HEART
4
THE HUMAN HEART
 Heart has four
chambers
 Right chambers
pump blood to lungs
to receive oxygen
 Left chambers pump
oxygenated blood
from lungs to rest of
the body
5
Cont…
 Right and left atria receive
blood
 Right and left ventricles pump
blood
 Valves produce one-way blood
flow from atria  ventricles 
arteries
 Energy to pump blood comes
from nutrients and oxygen in
blood
 The blood supply to the heart
is provided by coronary
arteries
6
Why heart substitutes fail?
 Immune response “rejects”
transplant or side effects due
to immune suppression
 Formation of clots
 Damage to red blood cells
 Lack of pulsatile blood flow
ARTIFICIAL HEART
HISTORY
7
Artificial heart are of three types
VENTRICULAR ARTIFICIAL HEART
VENTRICULAR ASSIST DEVICE
TOTALARTIFICIAL HEART
8
VENTRICULAR ARTIFICIAL
HEART
Each pump is small enough to be
implanted into the void that was left
behind from the extraction.
9
The jarvik-7 design incorporates two heart pumps that are connected to a
power console.
Both pumps receive power from a large external
console. The console pushes air through the
tubing.
Air enters inside the pump and is expelled
through a series of thin flexible diaphragms.
VENTRICULAR ASSIST
DEVICE
Michael has pioneered the development
of heart pumps since the early 1960s.
Ventricular assist device, invented by Dr Michael DeBakey was
implanted in 1966 at Methodist hospital in Texas.
11
In 1966, he performed the first successful
implantation of a ventricular assist device.
The patient's heart recovered while the VAD
took over its pumping chores.
TOTAL ARTIFICIAL
HEART
The AbioCor™ implantable replacement heart is the first completely self-contained
total artificial heart. It is the product of 30 years of research, development,
and testing conducted by ABIOMED, Inc. in order to extend and improve the lives of
patients who would otherwise die of heart failure.
13
ENERGY TRANSFER
14
 Electrical circulatory assist devices use
brushless dc motor as its pump
 Electrical energy is transferred to these devices
transcutaneously using a transcutaneous
transformer
 Transcutaneous transformer has large leakage
inductance which reduce its efficiency
 Dc-dc converter employing secondary side
resonance can be employed to alleviate this
problem but the transfer gain of voltage varies
widely with coupling coefficient
 Converter employing compensation of leakage
inductance on both sides of the transformer
offers stable gain and high efficiency
PROPOSED ENERGY
TRANSFERENCE SCHEME
16
17
Determination of Control region
 Gv curve is divided into 3 regions: low
frequency, middle frequency and high
frequency regions
 Region II provides maximum transfer
gain but is very sensitive to changes in
load and coupling coefficient, hence not
used
 Region I and III can control output
voltage
 Region III is desirable because the unity
gain frequencies is much less sensitive
than for region I
18
System Design
 Output requirements:
V0 = 24V
Iomax =2.0A
I0min =0.5A
 Size, geometry and core material of the
transformer and range of air gap and
misalignment between them are already
defined
 For transformer windings the same cores used
in series converter are used
System Design
 Transformer Core: Ferroxcube Pot Core 6656
3C8 Ferrite
OD=2.6in
Thickness=1.1in
Air gap=10-20mm
Misalignment=0-10mm
 Region III of gain characteristics is selected
for control
 Low value of Q is selected to reduce
sensitivity if variation
 Compensating resonant frequency is chosen at
120kHz
The AbioCor, along with other
components is surgically
implanted; it is designed to fit
within chest and abdomen.
ABIOCOR SYSTEM
21
• The AbioCor System consists of the following
implanted components:
 Replacement Heart
 Implanted TET
 Implanted Controller
 Implanted Battery
The thoracic unit weighs slightly more than two pounds (0.9 kg) and is
about the same size and shape of a natural heart.
It is made of titanium, and Angioflex, a polyurethane plastic.
REPLACEMENT HEART
The thoracic unit is implanted in the chest, and connects to
the right and left atria, the aorta, and the pulmonary artery.
The thoracic unit contains two hydraulic motors; one
keeps the blood pumping from each ventricle (blood
pump), and the other operates the motion of the four heart
valves.
23
IMPLANTED TRANSCUTANEOUS
ENERGY
TRANSMISSION (TET)
The implanted TET is an electric coil that provides
all of the AbioCor System’s internal devices with
electrical energy.
It is connected to the thoracic unit, the implanted
controller, and the implanted battery.
The implanted TET is located on the upper-left area
of the chest (opposite of the artificial heart).
24
The job of the implanted controller is to
oversee the internal components of the
AbioCor System.
The implanted controller is also able to
manage the artificial heart’s cardiac output
rate to make sure that the artificial heat
generates the necessary blood flow.
IMPLANTED CONTROLLER
The implanted controller is a small automatic computer located in the
abdomen of the patient’s body.
It is secured in a titanium case and connects to all internal
components.
25
The implanted battery is placed in the abdomen,
opposite from the implanted Controller.
It is implanted when the implanted controller and
the artificial heart are placed in the patient’s body.
The implanted battery is kept in a titanium case, it
receives energy from the external TET.
It is connected to all other internal components.
If the patient were to separate himself from the
external TET and battery pack (such as to take a
shower), the implanted battery would provide
energy for 30 - 40 minutes.
IMPLANTED BATTERY
26
External Components:
TRANSCUTANEOUS ENERGY
TRANSMISSION (TET)
PATIENT-CARRIED
ELECTRONICS.
PCE BATTERY BAG
PCE BATTERIES
PCE CONTROL MODULE
27
TRANSCUTANEOUS ENERGY
TRANSMISSION (TET)
The external TET is placed directly over the location of the internal
TET to transfer energy through the skin.
If the patient is stationary and is near a power outlet, his source for
energy may be the console.
If the patient is mobile and has
no intentions of remaining in
the same location for a long
period of time, he may use the
PCE as a power source.
28
PATIENT-CARRIED
ELECTRONICS
The patient using the AbioCor System is not
forced to stay in bed hooked up to the
system’s console;
He is also given the option to move around
and not have to depend on a power outlet to
power the system’s components.
If the patient chooses to be mobile(movable)
he may use the Patient-Carried Electronics
(PCE) by plugging the external TET into the
PCE’s control module.
29
PCE BATTERY BAG
PCE Battery Bag weighs : 10 pounds.
Carried by using : An attached shoulder strap (Abiomed).
Inside of the bag contains : Four batteries, plastic cardholders.
Outside of the bag contains : PCE control module.
30
PCE BATTERIES
Each pair of PCE Batteries supplies the AbioCor’s internal system with
power for about one hour (Abiomed).
The battery bag can carry two pairs of PCE batteries.
The internal system may be supplied with power for about two hours .
 Additionally, since the PCE batteries don’t last very long, they must be
changed several times a day so patient can take extra batteries if necessary.
31
PCE CONTROL MODULE
The PCE control module is to be placed in one
of the pockets of the PCE battery bag.
It is connected to the batteries by a battery cable
and is also connected to the external TET.
 If a problem occurs within one of the internal
devices, the control module immediately notifies
the patient.
32
To maintain operation, the AbioCor System
must first have a source of power depending
on whether or not the patient is mobile.
This power source will either be the console or
the PCE control module.
If the power source detects a problem, an
alarm light or an alarm sound notifies the
patient.
Otherwise, if no problems are detected the
AbioCor System follows a cyclic function and
continues to operate.
FUNCTION
33
COST OF IMPLANTATION
Complete heart replacement device can
cost about $75,000.
Procedure expenses cost about
$175,000.
It is financed by the national heart
research fund.
34
There are many obstacles to overcome before
any TAH is widely accepted.
The AbioCor System consists of a set of
internal components and external components.
The internal and external TETs work together
to convert this energy into usable energy for all
internal components.
CONCLUSION
35
• All of these provide power for the artificial
heart and components keep the artificial heart
pumping blood and keep sending that blood
throughout the patient’s body.
“ARTIFICIAL HEART IS NOT A
BRIDGE TO
TRANSPLANTATION BUT A LIFE
EXTENDING DEVICE”
37
REFERENCES
Abiomed. Product details.
http://www.abiomed.com/products/heart_replacement/product_
details.cfm
Bonsor, Kevin. How Artificial Hearts Work.
http://science.howstuffworks.com/artificial-heart.htm
Brain, Marshall. How Hydraulic Machines Work.
http://science.howstuffworks.com/hydraulic.htm
Cho, B.H., Gyu Bum Joun. “An energy transmission system
for an artificial heart using leakage inductance compensation
of transcutaneous transformer”. IEEE. Nov. 1998
http://ieeexplore.ieee.org/xpl/abs_free.jsp?arNumber=728328
Factmonster. heart, artificial.
<http://www.factmonster.com/ce6/sci/A0823119.html>
38
39

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The artificial heart

  • 1.
  • 2. An artificial heart is a prosthetic device that is implanted into the body to replace the biological heart. Artificial heart a pumping mechanism that duplicates the rate, output, and blood pressure of the natural heart; it may replace the function of a part or all of the heart. INTRODUCTION 2
  • 4. 4 THE HUMAN HEART  Heart has four chambers  Right chambers pump blood to lungs to receive oxygen  Left chambers pump oxygenated blood from lungs to rest of the body
  • 5. 5 Cont…  Right and left atria receive blood  Right and left ventricles pump blood  Valves produce one-way blood flow from atria  ventricles  arteries  Energy to pump blood comes from nutrients and oxygen in blood  The blood supply to the heart is provided by coronary arteries
  • 6. 6 Why heart substitutes fail?  Immune response “rejects” transplant or side effects due to immune suppression  Formation of clots  Damage to red blood cells  Lack of pulsatile blood flow
  • 8. Artificial heart are of three types VENTRICULAR ARTIFICIAL HEART VENTRICULAR ASSIST DEVICE TOTALARTIFICIAL HEART 8
  • 9. VENTRICULAR ARTIFICIAL HEART Each pump is small enough to be implanted into the void that was left behind from the extraction. 9 The jarvik-7 design incorporates two heart pumps that are connected to a power console.
  • 10. Both pumps receive power from a large external console. The console pushes air through the tubing. Air enters inside the pump and is expelled through a series of thin flexible diaphragms.
  • 11. VENTRICULAR ASSIST DEVICE Michael has pioneered the development of heart pumps since the early 1960s. Ventricular assist device, invented by Dr Michael DeBakey was implanted in 1966 at Methodist hospital in Texas. 11
  • 12. In 1966, he performed the first successful implantation of a ventricular assist device. The patient's heart recovered while the VAD took over its pumping chores.
  • 13. TOTAL ARTIFICIAL HEART The AbioCor™ implantable replacement heart is the first completely self-contained total artificial heart. It is the product of 30 years of research, development, and testing conducted by ABIOMED, Inc. in order to extend and improve the lives of patients who would otherwise die of heart failure. 13
  • 14. ENERGY TRANSFER 14  Electrical circulatory assist devices use brushless dc motor as its pump  Electrical energy is transferred to these devices transcutaneously using a transcutaneous transformer
  • 15.  Transcutaneous transformer has large leakage inductance which reduce its efficiency  Dc-dc converter employing secondary side resonance can be employed to alleviate this problem but the transfer gain of voltage varies widely with coupling coefficient  Converter employing compensation of leakage inductance on both sides of the transformer offers stable gain and high efficiency
  • 17. 17 Determination of Control region  Gv curve is divided into 3 regions: low frequency, middle frequency and high frequency regions  Region II provides maximum transfer gain but is very sensitive to changes in load and coupling coefficient, hence not used  Region I and III can control output voltage  Region III is desirable because the unity gain frequencies is much less sensitive than for region I
  • 18. 18
  • 19. System Design  Output requirements: V0 = 24V Iomax =2.0A I0min =0.5A  Size, geometry and core material of the transformer and range of air gap and misalignment between them are already defined  For transformer windings the same cores used in series converter are used
  • 20. System Design  Transformer Core: Ferroxcube Pot Core 6656 3C8 Ferrite OD=2.6in Thickness=1.1in Air gap=10-20mm Misalignment=0-10mm  Region III of gain characteristics is selected for control  Low value of Q is selected to reduce sensitivity if variation  Compensating resonant frequency is chosen at 120kHz
  • 21. The AbioCor, along with other components is surgically implanted; it is designed to fit within chest and abdomen. ABIOCOR SYSTEM 21
  • 22. • The AbioCor System consists of the following implanted components:  Replacement Heart  Implanted TET  Implanted Controller  Implanted Battery
  • 23. The thoracic unit weighs slightly more than two pounds (0.9 kg) and is about the same size and shape of a natural heart. It is made of titanium, and Angioflex, a polyurethane plastic. REPLACEMENT HEART The thoracic unit is implanted in the chest, and connects to the right and left atria, the aorta, and the pulmonary artery. The thoracic unit contains two hydraulic motors; one keeps the blood pumping from each ventricle (blood pump), and the other operates the motion of the four heart valves. 23
  • 24. IMPLANTED TRANSCUTANEOUS ENERGY TRANSMISSION (TET) The implanted TET is an electric coil that provides all of the AbioCor System’s internal devices with electrical energy. It is connected to the thoracic unit, the implanted controller, and the implanted battery. The implanted TET is located on the upper-left area of the chest (opposite of the artificial heart). 24
  • 25. The job of the implanted controller is to oversee the internal components of the AbioCor System. The implanted controller is also able to manage the artificial heart’s cardiac output rate to make sure that the artificial heat generates the necessary blood flow. IMPLANTED CONTROLLER The implanted controller is a small automatic computer located in the abdomen of the patient’s body. It is secured in a titanium case and connects to all internal components. 25
  • 26. The implanted battery is placed in the abdomen, opposite from the implanted Controller. It is implanted when the implanted controller and the artificial heart are placed in the patient’s body. The implanted battery is kept in a titanium case, it receives energy from the external TET. It is connected to all other internal components. If the patient were to separate himself from the external TET and battery pack (such as to take a shower), the implanted battery would provide energy for 30 - 40 minutes. IMPLANTED BATTERY 26
  • 27. External Components: TRANSCUTANEOUS ENERGY TRANSMISSION (TET) PATIENT-CARRIED ELECTRONICS. PCE BATTERY BAG PCE BATTERIES PCE CONTROL MODULE 27
  • 28. TRANSCUTANEOUS ENERGY TRANSMISSION (TET) The external TET is placed directly over the location of the internal TET to transfer energy through the skin. If the patient is stationary and is near a power outlet, his source for energy may be the console. If the patient is mobile and has no intentions of remaining in the same location for a long period of time, he may use the PCE as a power source. 28
  • 29. PATIENT-CARRIED ELECTRONICS The patient using the AbioCor System is not forced to stay in bed hooked up to the system’s console; He is also given the option to move around and not have to depend on a power outlet to power the system’s components. If the patient chooses to be mobile(movable) he may use the Patient-Carried Electronics (PCE) by plugging the external TET into the PCE’s control module. 29
  • 30. PCE BATTERY BAG PCE Battery Bag weighs : 10 pounds. Carried by using : An attached shoulder strap (Abiomed). Inside of the bag contains : Four batteries, plastic cardholders. Outside of the bag contains : PCE control module. 30
  • 31. PCE BATTERIES Each pair of PCE Batteries supplies the AbioCor’s internal system with power for about one hour (Abiomed). The battery bag can carry two pairs of PCE batteries. The internal system may be supplied with power for about two hours .  Additionally, since the PCE batteries don’t last very long, they must be changed several times a day so patient can take extra batteries if necessary. 31
  • 32. PCE CONTROL MODULE The PCE control module is to be placed in one of the pockets of the PCE battery bag. It is connected to the batteries by a battery cable and is also connected to the external TET.  If a problem occurs within one of the internal devices, the control module immediately notifies the patient. 32
  • 33. To maintain operation, the AbioCor System must first have a source of power depending on whether or not the patient is mobile. This power source will either be the console or the PCE control module. If the power source detects a problem, an alarm light or an alarm sound notifies the patient. Otherwise, if no problems are detected the AbioCor System follows a cyclic function and continues to operate. FUNCTION 33
  • 34. COST OF IMPLANTATION Complete heart replacement device can cost about $75,000. Procedure expenses cost about $175,000. It is financed by the national heart research fund. 34
  • 35. There are many obstacles to overcome before any TAH is widely accepted. The AbioCor System consists of a set of internal components and external components. The internal and external TETs work together to convert this energy into usable energy for all internal components. CONCLUSION 35
  • 36. • All of these provide power for the artificial heart and components keep the artificial heart pumping blood and keep sending that blood throughout the patient’s body.
  • 37. “ARTIFICIAL HEART IS NOT A BRIDGE TO TRANSPLANTATION BUT A LIFE EXTENDING DEVICE” 37
  • 38. REFERENCES Abiomed. Product details. http://www.abiomed.com/products/heart_replacement/product_ details.cfm Bonsor, Kevin. How Artificial Hearts Work. http://science.howstuffworks.com/artificial-heart.htm Brain, Marshall. How Hydraulic Machines Work. http://science.howstuffworks.com/hydraulic.htm Cho, B.H., Gyu Bum Joun. “An energy transmission system for an artificial heart using leakage inductance compensation of transcutaneous transformer”. IEEE. Nov. 1998 http://ieeexplore.ieee.org/xpl/abs_free.jsp?arNumber=728328 Factmonster. heart, artificial. <http://www.factmonster.com/ce6/sci/A0823119.html> 38
  • 39. 39