Artificial heart has provided a viable option for patient awaiting heart transplantation. Future developments on artificial hearts have the hope of eliminating the need for the transplantation completely.
3. Definition
The Human Heart
Heart Disease
The need for Heart Substitute
Design Process
Criteria for a Heart Substitute
The AbioCor Heart
How it works?
Surgical Procedure
AbioCor Design Criteria
Advantages and Disadvantages
ARTIFICIAL HEART
4. “An artificial organ is a man-made device that is
implanted into the human body to replace one or
many functions of a natural organ, which usually
are related to life support”.
ARTIFICIAL HEART
Life support to
prevent
awaiting a
transplant.
Dramatic
improvement of
the patient’s
ability for self
care.
Improvement of
patient’s ability
to interact
socially.
5. Heart has four
chambers
Right chambers
pump blood to lungs
to receive oxygen
Left chambers pump
oxygenated blood
from lungs to rest of
the body
ARTIFICIAL HEART
6. Right and left atria receive blood
Right and left ventricles pump blood
Valves produce one-way blood flow from atria →
ventricles → arteries
Energy to pump blood comes from nutrients and
oxygen in blood
The blood supply to the heart is provided by
coronary arteries
ARTIFICIAL HEART
7. Heart attack: blockage of coronary artery
damages portion of heart muscle
Congestive heart failure: gradual weakening of
heart
Millions suffer from heart disease
◦ Many cases are treatable with lifestyle changes, drugs
and/or surgery
◦ Surviving patients suffering from most severe cases
need new hearts!
ARTIFICIAL HEART
8. 600,000 Americans/year suffering from severe
heart disease need new hearts
Only 2,000 patients receive heart transplants
Conclusion: many patients die waiting for a new
heart!
A suitable alternative to donor hearts could
prolong thousands of lives
ARTIFICIAL HEART
9. Identify the problem or need to address
Specify details/criteria of an adequate solution to
your problem
Implement various solutions that meet the
criteria you specified
Test to determine which solution is most viable
Further testing to refine the solution you chose
ARTIFICIAL HEART
10. Process is iterative
◦ You need to repeat
various steps after testing
◦ Make design changes
based on test results
Failed designs
◦ Design didn’t meet criteria
◦ Could be due to
inappropriate criteria
ARTIFICIAL HEART
Identify Problem
Specify Criteria
Implement Design
Test Design
Refine Design
11. Must fit into chest cavity and connect to atria,
pulmonary artery and aorta quickly
Provide an adequate blood flow (8 – 10
liters/min)
Send deoxygenated blood to the lungs and
oxygenated blood to the body
Operate continuously for an indefinite period of
time
Provide adequate warning if something is wrong
or if it is going to fail
ARTIFICIAL HEART
12. Should increase/decrease blood flow based on
patient activity level
Should not evoke an immune response
No wires or tubes that penetrate the skin
Should not produce blood clots
Should not damage red blood cells
Ideally should have pulsatile blood flow
Many others we haven’t thought of!
ARTIFICIAL HEART
13. The AbioCor is the world’s first completely self
contained replacement heart.
A product of 3 decades research, development
and testing .
It is an advanced medical system being developed
by ABIOMED.
It is designed fully to sustain the body’s circulatory
system.
ARTIFICIAL HEART
14. Implanted into 59 year
old Robert Tools on July
2, 2001 at Jewish
Hospital in Louisville KY
(96 days)
Patient is able to walk
around, organs are
functioning normally,
undergoing daily
rehabilitation for
eventual release
ARTIFICIAL HEART
16. Internal Thoracic Unit
Two artificial ventricles along with valves
Internal motor driver
Internal Battery & External Battery
Energy Transformer Device (TET)
An internal miniaturized electronic package
ARTIFICIAL HEART
17. Hydraulic pump forces
blood to lungs and body
Power is provided by an
internal rechargeable
battery
Battery is recharged by
coils on surface and
below skin
Internal controller
monitors system and
controls pump speed
ARTIFICIAL HEART
18. Implant controller, battery
and coil
Connect patient to heart-
lung machine
Cut away ventricles
Sew grafts onto atria and
arteries
Connect implants to grafts
Remove patient from
heart-lung machine
ARTIFICIAL HEART
19. Grapefruit size, weighs 2 lbs, requires a 7 hour
surgery for implantation
Can provide up to 8 liters/min of blood to the
lungs and body
Has two chambers for pumping deoxygenated
blood to the lungs and oxygenated blood to the
body
Wireless energy transfer system allows for
continuous operation
Internal controller monitors operation
ARTIFICIAL HEART
20. Internal controller increases/decreases blood
flow based on blood oxygen levels
Materials are inert to the immune system
Completely contained within the chest – no wires
or tubing through skin!
Made of special materials and special pump
design to prevent clots and RBC damage
Pumping alternates between chambers, creating
a pulsatile blood flow
ARTIFICIAL HEART
22. It is readily available.
No piercing wires.
There is no need for immunosuppressive drugs, which
can compromise renal function & leave the patient
susceptible to infection.
For the persons who are not heart transplant
candidates, the artificial heart has allowed prolonged
time with family & friends & time to enjoy desired
activities.
ARTIFICIAL HEART
23. The artificial heart is not without risk:-
Those risks include wearing out or failure of the
electrical motor , infection & the need to take blood
thinners to prevent clotting.
Stroke & bleeding are also possible complications with
the artificial heart.
Larzer in size.
Not all patients have a body size that allows the
device to be implanted into the chest cavity, making
small persons unable to receive device.
ARTIFICIAL HEART
24. Artificial hearts need to be made of light but
durable materials.
It combines many principles of electronics,
material science, biology and physics.
Before the invention of the Artificial heart many
people died in awaiting of heart transplant.
It has played a very vital role in saving lives of
thousands of people who otherwise died of heart
failure.
ARTIFICIAL HEART