1. Electrolyte balance assists in regulating water balance, neuromuscular activity, and acid-base balance. The body can actively move electrolytes in and out of cells to maintain electrolyte balance in the right concentrations, which is important for fluid balance between compartments. Imbalanced electrolytes can cause issues like dehydration from exercise or illness.
2. Hyperkalemia, a high level of potassium, can cause lethal cardiac arrhythmias. It is defined as a serum potassium concentration higher than 5.5 mEq/L. Severe electrolyte imbalances can cause problems like coma and can be fatal if untreated.
3. Nursing interventions for a child at risk of infection
Fever in Critical Illness: Can the Critically Ill Take the HEAT? -Paul Young SMACC Conference
The febrile response to infection occurs in most animals and is regulated by a common biochemical mechanism involving prostaglandin E2. This common mechanism suggests that the response may have evolved in a common ancestor more than 350 million years ago. As the febrile response comes at a significant metabolic cost, its persistence across a broad range of species provides circumstantial evidence that the response has some evolutionary advantage. Furthermore, it logically follows that the components of the immune system would have evolved to function optimally in the physiological febrile range.
There are a number of historical examples of dramatic responses to treatment with therapeutic hyperthermia in some infectious diseases, including neurosyphilis and malaria. The relevance of these historical examples to the modern era is unclear. Furthermore, arguments based on the evolutionary importance of the febrile response do not necessarily apply to critically ill patients who are, by definition, supported beyond the limits of normal physiological homeostasis. Humans are not adapted to critical illness. In the absence of modern medicine and Intensive Care, most critically ill patients with fever and infection would presumably die. Among critically ill patients, it seems likely that there is a balance to be struck between the potential benefits of reducing metabolic rate that come with fever control and the potential risks of a deleterious effect on host defence mechanisms. Where this balance lies is very unclear as there are very few interventional studies of fever management in critically patients.
Remarkably, although paracetamol is very widely used in ICU patients with fever and infection, only one RCT, the HEAT trial, has investigated the safety and efficacy of administering paracetamol to critically ill patients with fever and infection. This talk gives the background to the HEAT trial which has now been published in the New England Journal of Medicine.
Links
• [The Bottom line] HEAT trial reviewed
• [NEJM article] Acetaminophen for Fever in Critically Ill Patients with Suspected Infection
• [NEJM supplement] Supplementary reading • [podcast] Paracetamol improves recovery in critically ill patients. Radio interview with Paul Young
• [other studies] Paracetamol therapy and outcome of critically ill patients: a multicenter retrospective observational study
Image result for ulcerative colitis
Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in your digestive tract. Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum. Symptoms usually develop over time, rather than suddenly.
Fever in Critical Illness: Can the Critically Ill Take the HEAT? -Paul Young SMACC Conference
The febrile response to infection occurs in most animals and is regulated by a common biochemical mechanism involving prostaglandin E2. This common mechanism suggests that the response may have evolved in a common ancestor more than 350 million years ago. As the febrile response comes at a significant metabolic cost, its persistence across a broad range of species provides circumstantial evidence that the response has some evolutionary advantage. Furthermore, it logically follows that the components of the immune system would have evolved to function optimally in the physiological febrile range.
There are a number of historical examples of dramatic responses to treatment with therapeutic hyperthermia in some infectious diseases, including neurosyphilis and malaria. The relevance of these historical examples to the modern era is unclear. Furthermore, arguments based on the evolutionary importance of the febrile response do not necessarily apply to critically ill patients who are, by definition, supported beyond the limits of normal physiological homeostasis. Humans are not adapted to critical illness. In the absence of modern medicine and Intensive Care, most critically ill patients with fever and infection would presumably die. Among critically ill patients, it seems likely that there is a balance to be struck between the potential benefits of reducing metabolic rate that come with fever control and the potential risks of a deleterious effect on host defence mechanisms. Where this balance lies is very unclear as there are very few interventional studies of fever management in critically patients.
Remarkably, although paracetamol is very widely used in ICU patients with fever and infection, only one RCT, the HEAT trial, has investigated the safety and efficacy of administering paracetamol to critically ill patients with fever and infection. This talk gives the background to the HEAT trial which has now been published in the New England Journal of Medicine.
Links
• [The Bottom line] HEAT trial reviewed
• [NEJM article] Acetaminophen for Fever in Critically Ill Patients with Suspected Infection
• [NEJM supplement] Supplementary reading • [podcast] Paracetamol improves recovery in critically ill patients. Radio interview with Paul Young
• [other studies] Paracetamol therapy and outcome of critically ill patients: a multicenter retrospective observational study
Image result for ulcerative colitis
Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in your digestive tract. Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum. Symptoms usually develop over time, rather than suddenly.
Diarrhea and vomiting in children
Vomiting (throwing up) and diarrhea (frequent, watery bowel movements) can be caused by viruses, bacteria, parasites, foods that are hard to digest (such as too many sweets) and other things.
Is defined as diarrhea with visible blood in
stools.
The most important and frequent cause of
acute dysentery is Shigella. Other causes
include Campylobacter jujeni, Salmonella,
and enteroinvasive E. coli.
Entameba histolytica causes dysentery in
older children but rarely in children under 5
years of age
Dysentery is specially sever in :-
1. Malnourished infants and children.
2.Those who develop clinically evident
dehydration during their illness. 3. Those who
are not breast fed. 4. Children with measles
or had measles in the preceding month.
5. Those who present with convulsion or
develop coma.
Acute renal failure nursing care plan & managementNursing Path
Is a sudden decline in renal function, usually marked by increased concentrations of blood urea nitrogen (BUN; azotemia) and creatinine; oliguria (less than 500 ml of urine in 24 hours); hyperkalemia; and sodium retention.
I bought this file from (FB name: Dee Dee). The files are extremely helpful, visit his Facebook account or Facebook page.
https://web.facebook.com/groups/670462807397676/
A much-quoted aphorism in medicine is “Listen to your patient and they are telling you the diagnosis”. Most often, the history reveals the diagnosis and sometimes, it is all that is required to make the diagnosis. Unfortunately, in this age of modern technology-based medicine, many busy clinicians fail to get a proper history and miss important dots in the history that connect to the diagnosis. This is clinically relevant, as a specific diagnosis completely alters the nature of treatment and thereby improves prognosis.
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Empowering the Data Analytics Ecosystem: A Laser Focus on Value
The data analytics ecosystem thrives when every component functions at its peak, unlocking the true potential of data. Here's a laser focus on key areas for an empowered ecosystem:
1. Democratize Access, Not Data:
Granular Access Controls: Provide users with self-service tools tailored to their specific needs, preventing data overload and misuse.
Data Catalogs: Implement robust data catalogs for easy discovery and understanding of available data sources.
2. Foster Collaboration with Clear Roles:
Data Mesh Architecture: Break down data silos by creating a distributed data ownership model with clear ownership and responsibilities.
Collaborative Workspaces: Utilize interactive platforms where data scientists, analysts, and domain experts can work seamlessly together.
3. Leverage Advanced Analytics Strategically:
AI-powered Automation: Automate repetitive tasks like data cleaning and feature engineering, freeing up data talent for higher-level analysis.
Right-Tool Selection: Strategically choose the most effective advanced analytics techniques (e.g., AI, ML) based on specific business problems.
4. Prioritize Data Quality with Automation:
Automated Data Validation: Implement automated data quality checks to identify and rectify errors at the source, minimizing downstream issues.
Data Lineage Tracking: Track the flow of data throughout the ecosystem, ensuring transparency and facilitating root cause analysis for errors.
5. Cultivate a Data-Driven Mindset:
Metrics-Driven Performance Management: Align KPIs and performance metrics with data-driven insights to ensure actionable decision making.
Data Storytelling Workshops: Equip stakeholders with the skills to translate complex data findings into compelling narratives that drive action.
Benefits of a Precise Ecosystem:
Sharpened Focus: Precise access and clear roles ensure everyone works with the most relevant data, maximizing efficiency.
Actionable Insights: Strategic analytics and automated quality checks lead to more reliable and actionable data insights.
Continuous Improvement: Data-driven performance management fosters a culture of learning and continuous improvement.
Sustainable Growth: Empowered by data, organizations can make informed decisions to drive sustainable growth and innovation.
By focusing on these precise actions, organizations can create an empowered data analytics ecosystem that delivers real value by driving data-driven decisions and maximizing the return on their data investment.
Levelwise PageRank with Loop-Based Dead End Handling Strategy : SHORT REPORT ...Subhajit Sahu
Abstract — Levelwise PageRank is an alternative method of PageRank computation which decomposes the input graph into a directed acyclic block-graph of strongly connected components, and processes them in topological order, one level at a time. This enables calculation for ranks in a distributed fashion without per-iteration communication, unlike the standard method where all vertices are processed in each iteration. It however comes with a precondition of the absence of dead ends in the input graph. Here, the native non-distributed performance of Levelwise PageRank was compared against Monolithic PageRank on a CPU as well as a GPU. To ensure a fair comparison, Monolithic PageRank was also performed on a graph where vertices were split by components. Results indicate that Levelwise PageRank is about as fast as Monolithic PageRank on the CPU, but quite a bit slower on the GPU. Slowdown on the GPU is likely caused by a large submission of small workloads, and expected to be non-issue when the computation is performed on massive graphs.
Data Centers - Striving Within A Narrow Range - Research Report - MCG - May 2...pchutichetpong
M Capital Group (“MCG”) expects to see demand and the changing evolution of supply, facilitated through institutional investment rotation out of offices and into work from home (“WFH”), while the ever-expanding need for data storage as global internet usage expands, with experts predicting 5.3 billion users by 2023. These market factors will be underpinned by technological changes, such as progressing cloud services and edge sites, allowing the industry to see strong expected annual growth of 13% over the next 4 years.
Whilst competitive headwinds remain, represented through the recent second bankruptcy filing of Sungard, which blames “COVID-19 and other macroeconomic trends including delayed customer spending decisions, insourcing and reductions in IT spending, energy inflation and reduction in demand for certain services”, the industry has seen key adjustments, where MCG believes that engineering cost management and technological innovation will be paramount to success.
MCG reports that the more favorable market conditions expected over the next few years, helped by the winding down of pandemic restrictions and a hybrid working environment will be driving market momentum forward. The continuous injection of capital by alternative investment firms, as well as the growing infrastructural investment from cloud service providers and social media companies, whose revenues are expected to grow over 3.6x larger by value in 2026, will likely help propel center provision and innovation. These factors paint a promising picture for the industry players that offset rising input costs and adapt to new technologies.
According to M Capital Group: “Specifically, the long-term cost-saving opportunities available from the rise of remote managing will likely aid value growth for the industry. Through margin optimization and further availability of capital for reinvestment, strong players will maintain their competitive foothold, while weaker players exit the market to balance supply and demand.”
1. Electrolyte Balance assist in regulation of water balance and is also essential for
neuromuscular activity and regulation of acid base balance. To enable to achieve
electrolyte balance we have to adjust fluid levels, the body can actively
move electrolytes in or out of cells. Thus, having electrolyte balance in the right
concentrations is important in maintaining fluid balance among the compartments.
Having imbalanced electrolytes causes an electrolyte imbalance, such as: fluid loss from
heavy exercise or physical activity. May cause vomiting and diarrhea, heart failure, kidney
disease, diabetes, and eating disorders. We have to balance it to live a healthy llifestyle.
1. What are the general appearance of a child with alterations in fluid and electrolyte:
a. Skin (2pts) = pale, cyanotic nail beds, dry and poor turgor
b. Cardiovascular (2pts) =pulse rate is weak, thread and poor indication of blood
pressure
c. Respiratory (2 pts) = change in rate, fluid overload and dehydration of hypovolemia
The upper limit may be considerably high in young or premature infants, as high as 6.5
mEq/L. Because hyperkalemia can cause lethal cardiac arrhythmia, it is one of the most
serious electrolyte disturbances. Hyperkalemia is defined as a serum potassium
concentration higher thancan cause respiratory paralysis or cardiac arrest
and can quickly be fatal. Severe electrolyte imbalances can cause serious problems such
as coma,This condition can be fatal if left undiagnosed and untreated.
Nursing Interventions for Hyperkalemia
Monitor cardiac, respiratory, neuromuscular, renal, and GI status
Stop IV potassium if running and hold any PO potassium supplements
Initiate potassium restricted diet and remember foods that are high in potassium
Remember the word POTASSIUM for food rich in potassium
2. What are the first sign commonly seen in a child with acute lymphocytic leukemia
(ALL)?
2. The most common signs and symptoms of acute lymphoblastic
leukemia in children are:
Swollen lymph nodes in your neck, armpits, stomach, or groin. Lymph nodes are pea-sized
glands in theseand other areas of your body.
Shortness of breath
Pain or fullness in your stomach, which may be becausethe diseasehas made your spleen
bigger
Fatigue
Night sweats
Fever and infections
Loss of appetite and weight
Bleeding from the gum
Bone pain
Frequent or severe nosebleeds
Pale skin
Prevent transfer of microorganism. Perform hand washing prior
giving care, utilize mask and gown when needed, provide a private room, monitor for
any signs and symptoms of infection.
Prevent oral trauma. Instruct the use of a soft-sponge toothbrush or sponge toothette
or gauze when rinsing the mouth; instruct to avoid foods which are hot, spicy, or high
in ascorbic acid (vitamin C); provide oral hygiene 30 minutes prior or after meals;
instruct to refrain from eating or drinking for 30 minutes after completion of oral
hygiene; and offer moist, soft, bland foods.
Prevent anxiety. Have the parents to stay with the child or encourage open visitation,
provide a telephone number to call for information; explain all procedures and care
in simple, direct, honest terms and repeat as often as necessary; reinforce physician
information if needed and provide specific information as needed; and provide
consistent nurse assignment with the same personnel; encourage parents to participate
in care.
3. Prevent injury. Avoid any palpation of abdominal mass; post sign on bed stating
not to palpate preoperatively; assess incision site for redness, swelling, drainage,
intactness, and healing and change dressing when soiled or wet; assess oral
and perineal area; and encourage parents to appropriately dress child based on weather
conditions and to refrain from participating on rough activities or sports.
Interventions Rationales
1. Assess for bleeding from any site and
febrile episodes; Monitor WBC, platelet count,
hematocrit, absolute neutrophil count.
Provides data about frank bleeding or
abnormal blood profiles that contribute
to bleeding induced by bone
marrow suppression and
immunosuppression due to chemotherapy.
2. Perform handwashing prior
giving care, utilize mask and gown when needed,
provide a private room, monitor for any signs and
symptoms of infection.
Prevents transfer of microorganism to a
weakened immune system during
chemotherapy if the absolute neutrophil
count is less than 1,000/cu mm.
3. Provides safety measures such as pad sides of bed,
use soft toothbrush, apply pressure for 5 minutes
after IV administration, avoidance of taking rectal
temperatures or performing unnecessary invasive
procedures.
Avoids bleeding caused by trauma during
the administration of chemotherapy which
changes platelet and clotting factor.
4. Instruct parents and child to avoid exposure to
persons having an upper respiratory infection or
any illness.
Prevents risk for infection in the highly
susceptible child.
5. Advise parents and child to avoid contact sports,
blowing nose hard, and straining at defecation.
Prevents trauma that causes bleeding.
6. Advise parents to report any fever,
behavior changes, headache,
dizziness, fatigue, pallor, slow oozing of blood
from any area, exposure to communicable
diseases.
Signifies an associated abnormal blood
profile complication.
4. 7. Teach and allow for return demonstration
of urine and stool testing for blood using dipstick
and hematest.
Identifies presence of bleeding in the
gastrointestinal or urinary tract.
8. Administer blood transfusion as ordered for severe
blood loss, monitor patency, vital signs, chills,
fever, urticaria, rash,
dyspnea, diaphoresis, headache
during transfusion, and terminate if any of these
changes occur.
Replaces blood loss when symptoms
of anemia appear (dizziness, pallor, fatigue,
increased pulse, and respiration) or when
Hct is less than 20% or platelet count
less than 20,000/cu mm.
7. Make one NCP for a child having a problem with risk for infection related to
decreased
immune function? (10pts)
Cues Nsg.
Diagno
sis
Obje
ctive
s
Intervention Evaluati
on
Subj
ectiv
e
Subje
ctive:“
medy
omahi
na na
kokes
a
dati,p
arang
angda
li
kodap
uan
Risk
for
infecti
on
related
to
compr
omised
immun
e
system
second
ary to
Hepa B
Short
termAft
er 2
hours
of nursi
ng
interve
ntion,p
atient
w ill:
-
Demon
stratedi
fferent
w ays
topreve
ntinfecti
on.Lon
g
termAft
er 3
days
Assess for the presence, existence of, and history of the
common causes of infection (listed above).
These factors represent a break in the body’s normal first line of defense a
Assess for the presence of local infectious processes in the skin
or mucous membranes.
Signs and symptoms include localized swelling, localized redness, pain or te
affected area, palpable heat.
Monitor white blood cell (WBC) count
An increasing WBC count indicates the body’s efforts to combat pathogens
Low: below 4,500
Normal: 4,500 – 11,000
High: more than 11,000
Very low WBC count may indicate a severe risk for infection. In older patien
without an increased WBC count. Additionally, WBC differential may show
infections.
Assess and monitor nutritional status, weight, history of weight
loss, and serum albumin.
Patients with poor nutritional status may be anergic or unable to muster a
pathogens making them susceptible to infection.
.After 2
hours
of nursing
intervention,
short term
goal is
fullymet as
evidenced
by:
Demonstrati
onof
differentway
s
topreventinf
ection
suchas:
monitoredvis
itors
assuggested
by
5. ngsaki
tngay
on.”O
bjectiv
e:-
hepati
tispati
ent-
PR =
57bp
mRisk
of nursi
ng
interve
ntion,p
atient
w ill:
w ill
notacq
uireinfe
ction
For pregnant clients, assess the intactness of amniotic
membranes.
Prolonged rupture of amniotic membranes before delivery puts the mothe
infection.
Investigate the use of medications or treatment modalities that
may cause immunosuppression.
Antineoplastic agents, corticosteroids, and so on, can reduce immunity.
Assess immunization status and history.
People with incomplete immunizations may not have sufficient acquired ac
during history taking when were they last immunized.
Monitor for signs and symptoms of infection. Signs and symptoms of infection vary according to the body area involved.
*Redness, swelling, increased pain, purulent discharge from
incisions, injury, and exit sites of tubes (IV tubings), drains, or
catheters.
These are the classic signs of infection. Any suspicious drainage should be c
determined by pathogens identified.
*Elevated temperature.
A temperature of up to 38º C (100.4º F) 48 hours post-op is usually related
temperature of greater than 37.7º (99.8º F) may indicate infection; very hi
sweating and chills may indicate septicemia.
*Color of respiratory secretions. Yellow or yellow-green sputum is indicative of respiratory infection.
*Appearance of urine. Cloudy, turbid, foul-smelling urine with visible sediment is indicative of urin
healthprovid
er.
Frequentpos
itionchanges
Coveringof
mouthby
thefamilyw h
enever they
cough.
After 3 days
of nursing
intervention,l
ong term
goals
arefully met
as
evidencedby
:
Absence
of infection.
.After 2 hours of nursing intervention,short termgoalis fullymet as evidenced by:
Demonstrationof differentways topreventinfection suchas:
monitoredvisitors assuggestedby healthprovider.
Frequentpositionchanges
Coveringof mouthby thefamilyw heneverthey cough.
After 3 days of nursing intervention,long termgoals arefully met as evidencedby:
Absence of infection.