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The Nervous
System: The Body's
Control Center
9

Part TwoPart Two

 Specialized cells in Central Nervous SystemCentral Nervous System
called neuroglia, or glial cells, perform
specialized functions. Four types:
Neuroglia-Glial CellsNeuroglia-Glial Cells

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
Metabolic andMetabolic and
structural supportstructural support

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
Attack MicrobesAttack Microbes
and removeand remove
debrisdebris

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
Cover and lineCover and line
cavities ofcavities of
nervous systemnervous system

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
Makes lipidMakes lipid
insulation calledinsulation called
myelinmyelin

 Specialized cells in Peripheral Nervous SystemPeripheral Nervous System
called neuroglia, or glial cells, perform
specialized functions. Two types:
Neuroglia-Glial CellsNeuroglia-Glial Cells

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
Makes myelinMakes myelin
for PNSfor PNS

 Specialized cells in nervous system called
neuroglia, or glial cells, perform specialized
functions
Nerve Tissue-Nerve Tissue-
Glial CellsGlial Cells
SupportSupport
cellscells

Figure 9-2
Glial cells and their functions.

 Each part of neuron has
specific function
 Body/SomaBody/Soma: cell
metabolism
 DendritesDendrites: receive
information from the
environment
 AxonAxon: generates and sends
signals to other cells
Nerve Tissue-TheNerve Tissue-The
NeuronNeuron

Figure 9-3
A neuron connecting to a
skeletal muscle.
Each part of neuron has
specific function:
Axon terminalAxon terminal: where
signal leaves cell
SynapseSynapse: where axon
terminal and
receiving cell
combine

Neurons
Neurons are classified by how they look (structure)
or what they do (function)
Neurons are classified by how they look (structure)
or what they do (function)

 Neurons can use their ability to generategenerate
electricityelectricity to send, receive, and interpret
signals
How Neurons WorkHow Neurons Work

 Neurons are called
excitableexcitable cells; this
simply means that if cell
is stimulated it can carry
small electrical chargesmall electrical charge.
 Each time charged
particles flow across a
cell membrane, there is
tiny charge generatedtiny charge generated
How Neurons WorkHow Neurons Work

 All three muscleAll three muscle types are
excitable cells, as are
many gland cells
 Cells are like miniatureminiature
batteriesbatteries, able to generate
tiny currents simply by
changing permeability of
their membranes
How Neurons WorkHow Neurons Work

 Series of
permeabilitypermeability
changeschanges within the
cell and the
resultant changes in
the charge across
the cell membrane
The Action PotentialThe Action Potential

The Action PotentialThe Action Potential
• Polarized
• Depolarized
• Repolarization
• Hyperpolarization
• Refractory
Changes in
the Cell

 A cell that is notnot
stimulatedstimulated or excited is
called a resting cellresting cell; it
is said to be polarizedpolarized
 It has a difference in
charge across its
membrane, being moremore
negative insidenegative inside than on
the outside cell
Resting Cell-PolarizedResting Cell-Polarized

 When cell is
stimulated, sodiumsodium
gatesgates in the cell
membrane spring
openopen, allowing sodium
to travel across
membrane
 Sodium bits are
positively chargedpositively charged, so
cell becomes more
positive as they enter
Stimulated Cell-Stimulated Cell-
DepolarizedDepolarized

 Sodium gates close after a few minutes and
potassium gates openpotassium gates open; potassium leaves cell,
taking its positive charge with it
RepolarizationRepolarization

 If cell becomes more
negative than resting
it is called
hyperpolarizedhyperpolarized
 Action potential (AP)
is cell moving
through
depolarization,depolarization,
repolarizationrepolarization, and
hyperpolarizationhyperpolarization
HyperpolarizationHyperpolarization

 Cell cannot accept another stimulus until it
returns to its resting state, and this time
period when it cannot accept another stimuluscannot accept another stimulus
is called refractoryrefractory period
Refractory PeriodRefractory Period

Figure 9-4
The action potential-
page 209.

 Speed of
impulse
conduction is
determined by
amount ofamount of
myelinmyelin and
diameter ofdiameter of
axonaxon
Myelin IncreasesMyelin Increases
ConductionConduction

 Myelin is lipidlipid
insulationinsulation or
sheath formed by
oligodendrocytesoligodendrocytes
in CNS and…
 Schwann celSchwann cells in
PNS
Myelin IncreasesMyelin Increases
ConductionConduction

Myelinated axon vs.Myelinated axon vs.
UnmyelinatedUnmyelinated
Myelin is essential
for speedy flow of
Action potential down
the axon
Un-myelinated axon
has to depolarize
each and everyeach and every
millimetermillimeter of axon
.5 meters/second.5 meters/second
100 meters/second100 meters/second

Figure 9-5
Wider axons conduct faster
Diameter of axonDiameter of axon
also affectsalso affects speed
of action potential
flow; wider the
diameter of axon,
faster the flow of
ions

Figure 9-5
Impulse conduction via
myelinated axon.
Nerve impulseNerve impulse
jumpsjumps from the
bare areas
between myelin
sheath called the
Nodes of RanvierNodes of Ranvier
which is FASTER

 Watch Video “How
Synapses Work”
https://www.youtube.com/wa
How Synapses WorkHow Synapses Work

 When AP* arrives at
axon terminal, terminalterminal
depolarizes and calciumdepolarizes and calcium
gates open;gates open; calcium ions
flows into cell; when
calcium flows in, it
triggers change in
terminal
How Synapses WorkHow Synapses Work
*Action potential

 There are tiny sacs in terminal called vesiclesvesicles
that release their contents from cell when
calcium flows in
How Synapses WorkHow Synapses Work
VesiclesVesicles

 Vesicles are filled
with molecules
called
neurotransmittersneurotransmitters
that send signal
from neuron across
synapse to next
cell in line
How Synapses WorkHow Synapses Work

 Once released the
neurotransmitter
binds to
receptors on
postsynaptic
membrane. Each
neurotransmitter
has a specific
receptor
How Synapses WorkHow Synapses Work
  The specific
neurotransmitter
determines
whether the
impulse continues
which is called
EXCITATION
allowing Sodium
(Na+) channels
to open and
membrane is
depolarized and
How Synapses WorkHow Synapses Work
Sodium channels
  The specific
neurotransmitter
determines
whether the
impulse is blocked
which is called
INHIBITION
allowing
Potassium (K+)
channels to open
and the impulse
STOPS
How Synapses WorkHow Synapses Work
Potassium channels
  The receptor then
releases the
neurotransmitter
after which it is
reabsorbed by the
synaptic knobs and
recycled or
destroyed by
enzymes.
How Synapses WorkHow Synapses Work
Enzymes

 Use of neurotransmitters is called chemicalchemical
synapsesynapse because chemicals carry informationchemicals carry information
from one cell to another
Chemical SynapseChemical Synapse
 Figure 9-6
. Step 1: The impulse travels down
the axon.
Step 2: Vesicles are stimulated to
release neurotransmitter
(exocytosis).
Step 3: The neurotransmitter
travels across the synapse and
binds with the receptor site of post
synaptic cell.
Step 4: The impulse continues
down the dendrite.
Chemical SynapseChemical Synapse

NeurotransmittersNeurotransmitters
Acetylcholine Generally excitatory, but
sometimes excitatory
Norepinephrine May be excitatory or
inhibitory depending on
receptor
Epinephrine May be excitatory or
inhibitory depending on
receptors
Serotonin Generally inhibitory
Endorphins Generally inhibitory

Clean up at theClean up at the
SynapseSynapse
After
neurotransmittersneurotransmitters
create a nerve
impulse at the
synapse,
enzymes
“reuptake” orreuptake” or
clean upclean up the
chemicals and
use them again

 Selective serotonin
reuptake inhibitors
(SSRIs) are
medications thatmedications that
preventprevent cleanupcleanup of
neurotransmitter
serotonin from
synapses, thus
increasing effects
of serotonin on
receiving cell
AntidepressantsAntidepressants

Electrical vs ChemicalElectrical vs Chemical
SynapseSynapse
• Cells do not need
chemicals to
transmit
information from
one cell to another
• Can transfer info
because of special
connection called
GAP JUNCTION
• Cells do not need
chemicals to
transmit
information from
one cell to another
• Can transfer info
because of special
connection called
GAP JUNCTION
Gap junction

Electrical SynapseElectrical Synapse
Electrical
synapses with
gap junction
are found in the
intercalated
discs of cardiac
muscle cells
Electrical
synapses with
gap junction
are found in the
intercalated
discs of cardiac
muscle cells

Electrical vs ChemicalElectrical vs Chemical
SynapseSynapse

In ClassIn Class
WORKSHEETWORKSHEET
Complete the worksheet using
ONLY YOUR NOTES-NO
TEXTBOOK or LAP TOPS,
TABLETS
You will not need to complete
the Chapter 9 worksheets for
credit but use simply for
STUDY GUIDE for your test

EXAM-Chapters 6 & 7EXAM-Chapters 6 & 7
Your exam is Tuesday Oct 29 at 9:30
a.m. It will have questions from:
•Power Point Presentations on
Chapter 6 & 7
•Essay on functions of skeletal
system
•Explain osteoporosis and cells of
bone formation
•Step by step of Muscle contraction
•Diagram on specific joint
•Extra credit: MUSCLE TONE page
149 in your textbook

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Surveyofanatomyandphysiologychap9parttwo 131021171528-phpapp01

  • 1. The Nervous System: The Body's Control Center 9
  • 3.   Specialized cells in Central Nervous SystemCentral Nervous System called neuroglia, or glial cells, perform specialized functions. Four types: Neuroglia-Glial CellsNeuroglia-Glial Cells
  • 4.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells Metabolic andMetabolic and structural supportstructural support
  • 5.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells Attack MicrobesAttack Microbes and removeand remove debrisdebris
  • 6.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells Cover and lineCover and line cavities ofcavities of nervous systemnervous system
  • 7.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells Makes lipidMakes lipid insulation calledinsulation called myelinmyelin
  • 8.   Specialized cells in Peripheral Nervous SystemPeripheral Nervous System called neuroglia, or glial cells, perform specialized functions. Two types: Neuroglia-Glial CellsNeuroglia-Glial Cells
  • 9.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells Makes myelinMakes myelin for PNSfor PNS
  • 10.   Specialized cells in nervous system called neuroglia, or glial cells, perform specialized functions Nerve Tissue-Nerve Tissue- Glial CellsGlial Cells SupportSupport cellscells
  • 11.  Figure 9-2 Glial cells and their functions.
  • 12.   Each part of neuron has specific function  Body/SomaBody/Soma: cell metabolism  DendritesDendrites: receive information from the environment  AxonAxon: generates and sends signals to other cells Nerve Tissue-TheNerve Tissue-The NeuronNeuron
  • 13.  Figure 9-3 A neuron connecting to a skeletal muscle. Each part of neuron has specific function: Axon terminalAxon terminal: where signal leaves cell SynapseSynapse: where axon terminal and receiving cell combine
  • 14.  Neurons Neurons are classified by how they look (structure) or what they do (function) Neurons are classified by how they look (structure) or what they do (function)
  • 15.   Neurons can use their ability to generategenerate electricityelectricity to send, receive, and interpret signals How Neurons WorkHow Neurons Work
  • 16.   Neurons are called excitableexcitable cells; this simply means that if cell is stimulated it can carry small electrical chargesmall electrical charge.  Each time charged particles flow across a cell membrane, there is tiny charge generatedtiny charge generated How Neurons WorkHow Neurons Work
  • 17.   All three muscleAll three muscle types are excitable cells, as are many gland cells  Cells are like miniatureminiature batteriesbatteries, able to generate tiny currents simply by changing permeability of their membranes How Neurons WorkHow Neurons Work
  • 18.   Series of permeabilitypermeability changeschanges within the cell and the resultant changes in the charge across the cell membrane The Action PotentialThe Action Potential
  • 19.  The Action PotentialThe Action Potential • Polarized • Depolarized • Repolarization • Hyperpolarization • Refractory Changes in the Cell
  • 20.   A cell that is notnot stimulatedstimulated or excited is called a resting cellresting cell; it is said to be polarizedpolarized  It has a difference in charge across its membrane, being moremore negative insidenegative inside than on the outside cell Resting Cell-PolarizedResting Cell-Polarized
  • 21.   When cell is stimulated, sodiumsodium gatesgates in the cell membrane spring openopen, allowing sodium to travel across membrane  Sodium bits are positively chargedpositively charged, so cell becomes more positive as they enter Stimulated Cell-Stimulated Cell- DepolarizedDepolarized
  • 22.   Sodium gates close after a few minutes and potassium gates openpotassium gates open; potassium leaves cell, taking its positive charge with it RepolarizationRepolarization
  • 23.   If cell becomes more negative than resting it is called hyperpolarizedhyperpolarized  Action potential (AP) is cell moving through depolarization,depolarization, repolarizationrepolarization, and hyperpolarizationhyperpolarization HyperpolarizationHyperpolarization
  • 24.   Cell cannot accept another stimulus until it returns to its resting state, and this time period when it cannot accept another stimuluscannot accept another stimulus is called refractoryrefractory period Refractory PeriodRefractory Period
  • 25.  Figure 9-4 The action potential- page 209.
  • 26.   Speed of impulse conduction is determined by amount ofamount of myelinmyelin and diameter ofdiameter of axonaxon Myelin IncreasesMyelin Increases ConductionConduction
  • 27.   Myelin is lipidlipid insulationinsulation or sheath formed by oligodendrocytesoligodendrocytes in CNS and…  Schwann celSchwann cells in PNS Myelin IncreasesMyelin Increases ConductionConduction
  • 28.  Myelinated axon vs.Myelinated axon vs. UnmyelinatedUnmyelinated Myelin is essential for speedy flow of Action potential down the axon Un-myelinated axon has to depolarize each and everyeach and every millimetermillimeter of axon .5 meters/second.5 meters/second 100 meters/second100 meters/second
  • 29.  Figure 9-5 Wider axons conduct faster Diameter of axonDiameter of axon also affectsalso affects speed of action potential flow; wider the diameter of axon, faster the flow of ions
  • 30.  Figure 9-5 Impulse conduction via myelinated axon. Nerve impulseNerve impulse jumpsjumps from the bare areas between myelin sheath called the Nodes of RanvierNodes of Ranvier which is FASTER
  • 31.   Watch Video “How Synapses Work” https://www.youtube.com/wa How Synapses WorkHow Synapses Work
  • 32.   When AP* arrives at axon terminal, terminalterminal depolarizes and calciumdepolarizes and calcium gates open;gates open; calcium ions flows into cell; when calcium flows in, it triggers change in terminal How Synapses WorkHow Synapses Work *Action potential
  • 33.   There are tiny sacs in terminal called vesiclesvesicles that release their contents from cell when calcium flows in How Synapses WorkHow Synapses Work VesiclesVesicles
  • 34.   Vesicles are filled with molecules called neurotransmittersneurotransmitters that send signal from neuron across synapse to next cell in line How Synapses WorkHow Synapses Work
  • 35.   Once released the neurotransmitter binds to receptors on postsynaptic membrane. Each neurotransmitter has a specific receptor How Synapses WorkHow Synapses Work
  • 36.   The specific neurotransmitter determines whether the impulse continues which is called EXCITATION allowing Sodium (Na+) channels to open and membrane is depolarized and How Synapses WorkHow Synapses Work Sodium channels
  • 37.   The specific neurotransmitter determines whether the impulse is blocked which is called INHIBITION allowing Potassium (K+) channels to open and the impulse STOPS How Synapses WorkHow Synapses Work Potassium channels
  • 38.   The receptor then releases the neurotransmitter after which it is reabsorbed by the synaptic knobs and recycled or destroyed by enzymes. How Synapses WorkHow Synapses Work Enzymes
  • 39.   Use of neurotransmitters is called chemicalchemical synapsesynapse because chemicals carry informationchemicals carry information from one cell to another Chemical SynapseChemical Synapse
  • 40.  Figure 9-6 . Step 1: The impulse travels down the axon. Step 2: Vesicles are stimulated to release neurotransmitter (exocytosis). Step 3: The neurotransmitter travels across the synapse and binds with the receptor site of post synaptic cell. Step 4: The impulse continues down the dendrite. Chemical SynapseChemical Synapse
  • 41.  NeurotransmittersNeurotransmitters Acetylcholine Generally excitatory, but sometimes excitatory Norepinephrine May be excitatory or inhibitory depending on receptor Epinephrine May be excitatory or inhibitory depending on receptors Serotonin Generally inhibitory Endorphins Generally inhibitory
  • 42.  Clean up at theClean up at the SynapseSynapse After neurotransmittersneurotransmitters create a nerve impulse at the synapse, enzymes “reuptake” orreuptake” or clean upclean up the chemicals and use them again
  • 43.   Selective serotonin reuptake inhibitors (SSRIs) are medications thatmedications that preventprevent cleanupcleanup of neurotransmitter serotonin from synapses, thus increasing effects of serotonin on receiving cell AntidepressantsAntidepressants
  • 44.  Electrical vs ChemicalElectrical vs Chemical SynapseSynapse • Cells do not need chemicals to transmit information from one cell to another • Can transfer info because of special connection called GAP JUNCTION • Cells do not need chemicals to transmit information from one cell to another • Can transfer info because of special connection called GAP JUNCTION Gap junction
  • 45.  Electrical SynapseElectrical Synapse Electrical synapses with gap junction are found in the intercalated discs of cardiac muscle cells Electrical synapses with gap junction are found in the intercalated discs of cardiac muscle cells
  • 46.  Electrical vs ChemicalElectrical vs Chemical SynapseSynapse
  • 47.  In ClassIn Class WORKSHEETWORKSHEET Complete the worksheet using ONLY YOUR NOTES-NO TEXTBOOK or LAP TOPS, TABLETS You will not need to complete the Chapter 9 worksheets for credit but use simply for STUDY GUIDE for your test
  • 48.  EXAM-Chapters 6 & 7EXAM-Chapters 6 & 7 Your exam is Tuesday Oct 29 at 9:30 a.m. It will have questions from: •Power Point Presentations on Chapter 6 & 7 •Essay on functions of skeletal system •Explain osteoporosis and cells of bone formation •Step by step of Muscle contraction •Diagram on specific joint •Extra credit: MUSCLE TONE page 149 in your textbook