This document discusses the benefits and considerations of pre-registration for scientific studies. It addresses common misconceptions about pre-registration and provides guidance on how to properly pre-register a study. Pre-registration involves outlining the key elements of a study such as hypotheses, methods, and analysis plan prior to conducting the research. This helps reduce biases and distinguishes exploratory from confirmatory research. The document recommends pre-registering studies using public repositories like AsPredicted.org to increase transparency and reproducibility in science.