Motivation for Research
in Radiology
Elizabeth A. Krupinski, PhD
Department Radiology & Imaging Sciences
Emory University
Why Do Research?
• Bad but common reasons
– Cuz I have to
– Cuz it gets me out of that clinical stuff
• Lofty reasons
– I want to cure cancer
– I want to win a Nobel prize
• Good reasons
– Better able & more critically review literature
– Clinical thinking skills more evidence-based
– Connections & collaborations
Imaging-Related Research at NIH
as Function All NIH Funding
M
i
l
l
i
o
n
s
Kalutkiewicz & Ehman Patents as proxies; NIH hubs in innovation.
Nature Biotech 2014;32:536-537
What Does it Take to Excel?
Passion & Patience!
• It has to come from within
• Projects assigned by others may get you
started but your ideas pave long-term path
• It’s OK to explore!
• Use every day experiences to find questions
• Read journals, attend meetings, ID gaps
• Attend GR & RIPS! Other departments too
Seek Mentorship!
• Most faculty willing to meet, talk, help
• Most people have multiple mentors
– Different goals
– Different aspects work/life
• Don’t wait
• Don’t be afraid to ask
Good Mentors
• Active listeners
• Dedicated to their success
• Dedicated to success others
• Willing to go to bat for others
• Engaged – know the big picture
• Willing to explore outside comfort zone
• Respectful, responsible, ready
Mentorship Goals
• Chemistry – bonds
– Assigned vs chosen
• Formal vs informal
• Mutual goals & expectations
• Career advice vs mentorship
• Diversity
Getting Started
• Create plan – 1, 3, 5 year (maybe longer)
– Who, what, where, why, when
• Put your CV in order
• Get possible mentor CVs
– Not just publications etc.
– Who have they mentored/worked with
• Ask others who the good mentors are
• Not just senior & famous faculty
• Use templates when you can
• Ask others how they see you/your goals
• Get feedback – throughout career
• Be willing to change course
• Diversify
Do you have a formal mentoring program for junior faculty?
Krupinski & Votaw Acad Rad 2015;22:918-932
Factors limiting junior faculty advancement (according to VC-R)
Emory CTSA
• Clinical and Translational Science Award:
large infrastructure grant to support clinical
& translational research to speed bench-to-
bedside translation of discoveries
• Funding, newsletter, resources
http://medicine.emory.edu/research/internal-research-re
Alignment With NCATS
National Center for Advancing Translational Sciences: NCATS develops innovations to
reduce, remove or bypass costly & time-consuming bottlenecks in translational science
process, to speed development & delivery new drugs, diagnostics, medical devices &
behavioral interventions to patients https://ncats.nih.gov/
MS Clinical Research
• http://medicine.emory.edu/research/whats-
up/announcements/MSCR-2013.html
• Emory MSCR part of Research Education, Training, &
Career Development (RETCD) program ACTSI
• MSCR provides didactic & mentored clinical &/or
translational research training
• Designed for participants who hold doctorate or
equivalent degree (physicians, fellows, jr faculty) & have
demonstrated commitment to career in clinical
investigation that incorporates clinical &/or translational
research
Ethical Conduct of Research
• Responsibility and Authority for your Research
• Integrity and Quality of Research Data
• Authorship Matters
• Research Mentorship/Supervision of
Students/Trainees
• Education of those trainees in Ethical Principles
• Conflict of Interest
• Disclosure vs reporting
• Medical Professionalism
• Informed Consent and Social Responsibility
Resources
• Office Compliance http://compliance.emory.edu/
• ACTSI http://www.atlantactsi.org/
• ACTSI Ethical Dilemmas
http://www.actsi.org/discovery/ethics-
center.html
• Start early – early exposure most predictive
success
– Past productivity = future productivity
• Attend workshops
– Grant writing, paper writing, research
• RSNA, AUR, ARRS
• Dept & university
• Present
– Locally & nationally
Funding
• Diversity is key!
• Junior faculty/career development awards
– Societies, foundations, federal
– Explore travel grants
• Collaborate! Get on others’ grants
• Be persistent – it will take time & multiple tries
• Use Grant Review Committee!!!!
Getting Started Without Funds
- Retrospective for hypothesis building
- Data mining existing databases
- Pursue clinically impactful project
- Find lab similar interests & volunteer
- No experience – act as postdoc
- Experience – select project within
scope mentor’s interest & strength
- Seek startups awards
- Branch off & work towards independence
Good Early Sources
• Specialty societies
– RSNA, AUR, SNMMI, SIR, SAR etc.
• AHA, Dana Foundation, Gates Foundation,
ACS, Ryan White, Komen
RSNA
• http://rsna.org/Grants-and-Awards/
• Education Scholar Grant: $75,000 1 yr
• RSNA/AUR/APDR/SCARD Radiology Education Research
Development Grant: $10,000 1 yr
• Research Scholar Grant: $150,000 2 yrs
• Research Resident/Fellow Grant: $30,000/$50,000 1 yr
• Research Seed Grant: $40,000 1 yr
• Research Medical Student Grant: $3,000 10 wk + dept
match
• http://rsna.org/Grants-and-Awards/
AUR Radiology Research Alliance
• http://www.aur.org/uploadedFiles/Alliances/RRA/
rra_compendium.pdf
• Research Initiatives in Radiology and the
Radiological Sciences (2005, being updated)
– NIH (NCI, NIBIB, and molecular imaging)
– ACRIN, ARRS, AAR, ARRS, ISMRM, RRA/AUR,
RSNA)
– AIMBE (American Institute Med & Biol Eng),
AAPM (Am Assn Physicists Med)
Routing Administrative Items
• PI Eligibility Form: To certify in EPEX must first
be set-up so need to complete PI Eligibility Form
• eCOI: Every proposal requires eCOI form - pre-
award specialist will set up in eCOI system & you
receive system generated email asking complete
• Budget template: Requires use internal budget
template to calculate costs
– Several types taking into account fringe rate(s)
during proposed performance period
– Pre-award specialist will select most
appropriate budget template & assist you with
allocating funds
Where To Start?
•Notify Vice Chair Research/Dept Chair
•Notify Mentor/Supervisor
•Notify RAS - C&I Office
•Complete Intent to Submit form
https://redcap.emory.edu/surveys/?s=YTCJK7333X
%20
GET INSPIRED!!
Questions?
ekrupin@emory.edu

Motivation for Research in Radiology

  • 1.
    Motivation for Research inRadiology Elizabeth A. Krupinski, PhD Department Radiology & Imaging Sciences Emory University
  • 4.
    Why Do Research? •Bad but common reasons – Cuz I have to – Cuz it gets me out of that clinical stuff • Lofty reasons – I want to cure cancer – I want to win a Nobel prize • Good reasons – Better able & more critically review literature – Clinical thinking skills more evidence-based – Connections & collaborations
  • 6.
    Imaging-Related Research atNIH as Function All NIH Funding M i l l i o n s
  • 7.
    Kalutkiewicz & EhmanPatents as proxies; NIH hubs in innovation. Nature Biotech 2014;32:536-537
  • 8.
    What Does itTake to Excel?
  • 9.
    Passion & Patience! •It has to come from within • Projects assigned by others may get you started but your ideas pave long-term path • It’s OK to explore! • Use every day experiences to find questions • Read journals, attend meetings, ID gaps • Attend GR & RIPS! Other departments too
  • 10.
    Seek Mentorship! • Mostfaculty willing to meet, talk, help • Most people have multiple mentors – Different goals – Different aspects work/life • Don’t wait • Don’t be afraid to ask
  • 11.
    Good Mentors • Activelisteners • Dedicated to their success • Dedicated to success others • Willing to go to bat for others • Engaged – know the big picture • Willing to explore outside comfort zone • Respectful, responsible, ready
  • 12.
    Mentorship Goals • Chemistry– bonds – Assigned vs chosen • Formal vs informal • Mutual goals & expectations • Career advice vs mentorship • Diversity
  • 13.
    Getting Started • Createplan – 1, 3, 5 year (maybe longer) – Who, what, where, why, when • Put your CV in order • Get possible mentor CVs – Not just publications etc. – Who have they mentored/worked with • Ask others who the good mentors are • Not just senior & famous faculty
  • 15.
    • Use templateswhen you can • Ask others how they see you/your goals • Get feedback – throughout career • Be willing to change course • Diversify
  • 16.
    Do you havea formal mentoring program for junior faculty? Krupinski & Votaw Acad Rad 2015;22:918-932
  • 17.
    Factors limiting juniorfaculty advancement (according to VC-R)
  • 19.
    Emory CTSA • Clinicaland Translational Science Award: large infrastructure grant to support clinical & translational research to speed bench-to- bedside translation of discoveries • Funding, newsletter, resources http://medicine.emory.edu/research/internal-research-re
  • 20.
    Alignment With NCATS NationalCenter for Advancing Translational Sciences: NCATS develops innovations to reduce, remove or bypass costly & time-consuming bottlenecks in translational science process, to speed development & delivery new drugs, diagnostics, medical devices & behavioral interventions to patients https://ncats.nih.gov/
  • 21.
    MS Clinical Research •http://medicine.emory.edu/research/whats- up/announcements/MSCR-2013.html • Emory MSCR part of Research Education, Training, & Career Development (RETCD) program ACTSI • MSCR provides didactic & mentored clinical &/or translational research training • Designed for participants who hold doctorate or equivalent degree (physicians, fellows, jr faculty) & have demonstrated commitment to career in clinical investigation that incorporates clinical &/or translational research
  • 22.
    Ethical Conduct ofResearch • Responsibility and Authority for your Research • Integrity and Quality of Research Data • Authorship Matters • Research Mentorship/Supervision of Students/Trainees • Education of those trainees in Ethical Principles • Conflict of Interest • Disclosure vs reporting • Medical Professionalism • Informed Consent and Social Responsibility
  • 23.
    Resources • Office Compliancehttp://compliance.emory.edu/ • ACTSI http://www.atlantactsi.org/ • ACTSI Ethical Dilemmas http://www.actsi.org/discovery/ethics- center.html
  • 24.
    • Start early– early exposure most predictive success – Past productivity = future productivity • Attend workshops – Grant writing, paper writing, research • RSNA, AUR, ARRS • Dept & university • Present – Locally & nationally
  • 25.
    Funding • Diversity iskey! • Junior faculty/career development awards – Societies, foundations, federal – Explore travel grants • Collaborate! Get on others’ grants • Be persistent – it will take time & multiple tries • Use Grant Review Committee!!!!
  • 26.
    Getting Started WithoutFunds - Retrospective for hypothesis building - Data mining existing databases - Pursue clinically impactful project - Find lab similar interests & volunteer - No experience – act as postdoc - Experience – select project within scope mentor’s interest & strength - Seek startups awards - Branch off & work towards independence
  • 27.
    Good Early Sources •Specialty societies – RSNA, AUR, SNMMI, SIR, SAR etc. • AHA, Dana Foundation, Gates Foundation, ACS, Ryan White, Komen
  • 28.
    RSNA • http://rsna.org/Grants-and-Awards/ • EducationScholar Grant: $75,000 1 yr • RSNA/AUR/APDR/SCARD Radiology Education Research Development Grant: $10,000 1 yr • Research Scholar Grant: $150,000 2 yrs • Research Resident/Fellow Grant: $30,000/$50,000 1 yr • Research Seed Grant: $40,000 1 yr • Research Medical Student Grant: $3,000 10 wk + dept match • http://rsna.org/Grants-and-Awards/
  • 29.
    AUR Radiology ResearchAlliance • http://www.aur.org/uploadedFiles/Alliances/RRA/ rra_compendium.pdf • Research Initiatives in Radiology and the Radiological Sciences (2005, being updated) – NIH (NCI, NIBIB, and molecular imaging) – ACRIN, ARRS, AAR, ARRS, ISMRM, RRA/AUR, RSNA) – AIMBE (American Institute Med & Biol Eng), AAPM (Am Assn Physicists Med)
  • 30.
    Routing Administrative Items •PI Eligibility Form: To certify in EPEX must first be set-up so need to complete PI Eligibility Form • eCOI: Every proposal requires eCOI form - pre- award specialist will set up in eCOI system & you receive system generated email asking complete • Budget template: Requires use internal budget template to calculate costs – Several types taking into account fringe rate(s) during proposed performance period – Pre-award specialist will select most appropriate budget template & assist you with allocating funds
  • 31.
    Where To Start? •NotifyVice Chair Research/Dept Chair •Notify Mentor/Supervisor •Notify RAS - C&I Office •Complete Intent to Submit form https://redcap.emory.edu/surveys/?s=YTCJK7333X %20 GET INSPIRED!!
  • 32.