This document discusses key concepts in publication ethics. It provides background on COPE guidelines from 2007 which are widely used, and a COPE survey from 2008-2009 that found editors were not very concerned with ethics. It describes COPE audits from 2009-2011 that provided guidance to editors. Key ethical considerations discussed are transparency around funding, authorship, and previous publication; research integrity regarding misconduct, informed consent, and informing readers of problems; and editorial standards regarding peer review, conflicts of interest, and independence.