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1 Solving Medical Mysteries Hidden Stress & Unexplained Symptoms David D. Clarke, MD
2 A Baffling Illness
3 Stress Illness    Illness caused by past or present     psycho-social stress.
4 The Third Illness Class Psychiatric Stress Organic
5 Cause of Presenting Symptoms
6 A Wide Range of Presentations
7 Women Undergoing Laparoscopy
8 Costly and Frustrating No definitive tests Frequent referrals & “mega-workups” False positive tests Serious illness is ruled out but the patient remains ill
9 Symptoms Relieved after a Nine Month Negative Work-Up
10 A note from the Referring Physician “Thank you for helping her.  It is reassuring to know that I didn’t miss anything important.”
11 Gaining The Patient’s  Confidence and Cooperation  Stress Symptoms
12 Two Simple Concepts Stress Causes Real Symptoms Effective Treatment is Available
13 Stress History Part I  Current Stress
14 Stress History Part I - a  Insufficient Personal Time
15 Stress History Part II Childhood Stress
16 Adverse Childhood Experience Study Seven Factors Measured (n=18,000) Abuse:                             1. Physical   			                    2. Sexual    			                    3. Psychological Household Occurrences:     4. Substance Abuse   			                    5. Mental Illness                                        6. Domestic Violence                                        7. Householder Imprisoned
17 4+ ACEs vs Zero ACEs Odds Ratios IV Drug Use                  11.0 Suicide Attempt              9.5 Alcohol Abuse                5.3 Domestic Violence          5.0 Multiple Somatic Sx        2.7 COPD                            2.4 Obesity		       1.8
18 Stress History Part III Depression
19 Stress History Part IV Post-Traumatic Stress
20 Stress History Part V - a Generalized Anxiety Disorder
21 Stress History Part V - b Social Anxiety Disorder
22 Stress History Part V - c Panic Disorder
23 Treatment of Current Stress Listing Your Stresses
24 Treatment of Current Stress Self-Care Time
25 Treatment of Current Stress  Relaxation Technique
26 Treatment of Childhood Stress  Acknowledge Their Heroism
27 Treatment of Childhood Stress Writing
28 Treatment of Childhood Stress Reading
29 Treatment of Childhood Stress Support Groups
30 Treatment of Childhood Stress  Mental Health Counseling
31 Treatment of  Depression, PTSD & Anxiety  Medication
32 Treatment of  Depression, PTSD & Anxiety  Mental Health Counseling
33 The Mystery Solved
34 Another Mystery
35 Linda’s 550 Days
36 Somatic Expression of Rage
37 The Talking Cure
38 Stress Causes Real Symptoms
39 Effective Treatment is Available
40 The Stress Medicine Specialist Master’s Degree in Mental Health Work in Primary Care Available for “Instant Consults” Mutual education with Primary Care
41 What if there was a blood test for stress illness?
42 Until there is a blood test… “Wonderful.” (Yale) “Truly remarkable.” (UNC) “Extremely valuable.” (Berkeley) “A spectacular accomplishment.” (OHSU) www.stressillness.com

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Stress Medicine by Prof David Clarke (USA)