This document discusses stem cell therapy and research. It defines stem cells as undifferentiated cells that can differentiate into specialized cell types and have self-renewal properties. There are two main types of stem cells - embryonic stem cells which are pluripotent and can become any cell type, and adult stem cells which are multipotent and more limited in differentiation potential. Current stem cell therapy applications include treatments for cancers, blood disorders, diabetes, vision and hearing loss, Parkinson's disease, and more. However, obstacles remain around identifying the right stem cell types and controlling differentiation.
Stem cell Therapy in Neurological diseases Ibad khan
Stem cell Therapy in Neurological diseases
difinition
mechanism
types
history
advantages or disadvantages
in this presentation all theses information include ,
Stem cell Therapy in Neurological diseases Ibad khan
Stem cell Therapy in Neurological diseases
difinition
mechanism
types
history
advantages or disadvantages
in this presentation all theses information include ,
Stem cell technology | Presented by pranjali V. Bhadanepranjali bhadane
This presentation is related to biological topic stem cell technology. stem cell technology plays an important role in life science. stem cell technology is most important for future researchers on personal genomics, personal drug and Complex Disease Research...
This slide is about the potential uses of stem cells. It describes how they are useful and also puts froward the extraction process and the ares in which stem cells prove to be extremely useful. This slide also lists the various from of cells and the difference between stem cells and the normal differentiated cells. It is also richly supplied with photos and content which would altogether increase the quality of the slide. Hope you enjoy and learn. Please do like and follow. Share with your friends who might benefit from this.
STEM CELLS ARE THE UNDIFFERENTIATED CELLS LATER THEIR DIFFERENTIATION TAKES PLACE WHICH LET THEM TO CONVERT INTO SPECIALIZED CELLS CALLED AS STEM CELLS.
Stem cells are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity.
Stem cell therapy is the most advance therapy which use stem cells to treat or prevent a disease or condition.
Properties, types and uses of stem cells are summarized in this presentation.
Role of Pharmacognosy in allopathy and traditional systems of medicineShiv Kumar
Role of Pharmacognosy in allopathy and traditional system of medicine, Allopathy or modern system of medicine. Ayurvedic system of medicine, Unani system of medicine, Siddha system of medicine, Homeopathy system of medicine, Chinese system of medicine, Alternative system of medicine, Traditional system of medicine
Stem cell technology | Presented by pranjali V. Bhadanepranjali bhadane
This presentation is related to biological topic stem cell technology. stem cell technology plays an important role in life science. stem cell technology is most important for future researchers on personal genomics, personal drug and Complex Disease Research...
This slide is about the potential uses of stem cells. It describes how they are useful and also puts froward the extraction process and the ares in which stem cells prove to be extremely useful. This slide also lists the various from of cells and the difference between stem cells and the normal differentiated cells. It is also richly supplied with photos and content which would altogether increase the quality of the slide. Hope you enjoy and learn. Please do like and follow. Share with your friends who might benefit from this.
STEM CELLS ARE THE UNDIFFERENTIATED CELLS LATER THEIR DIFFERENTIATION TAKES PLACE WHICH LET THEM TO CONVERT INTO SPECIALIZED CELLS CALLED AS STEM CELLS.
Stem cells are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity.
Stem cell therapy is the most advance therapy which use stem cells to treat or prevent a disease or condition.
Properties, types and uses of stem cells are summarized in this presentation.
Role of Pharmacognosy in allopathy and traditional systems of medicineShiv Kumar
Role of Pharmacognosy in allopathy and traditional system of medicine, Allopathy or modern system of medicine. Ayurvedic system of medicine, Unani system of medicine, Siddha system of medicine, Homeopathy system of medicine, Chinese system of medicine, Alternative system of medicine, Traditional system of medicine
shikimic acid pathway, amino acid pathway, acetate mevalonate pathway, biosynthesis of ephedrine, biosynthesis of quinine, biosynthesis of brucine, biosynthesis of strychnine, biosynthesis of piperine, biosynthesis of berberine, biosynthesis of taxol, biosynthesis of vincristine, biosynthesis of vinblastine, biosynthesis of digitoxin, biosynthesis of glycyrrhizine, biosynthesis of sennosides, biosynthesis of bacoside, biosynthesis of quercitine, biosynthesis of hecogenin, biosynthesis of guggulosterone, biosynthesis of withanolides, biosynthesis of cucurbitacine, biosynthesis of umbelliferone, biosynthesis of atropine
red reishi good natural remedy for health, importance of red reishi, reishi pharmacognosy, chemical composition of red reishi, pharmacological uses of red reishi
How to Create Map Views in the Odoo 17 ERPCeline George
The map views are useful for providing a geographical representation of data. They allow users to visualize and analyze the data in a more intuitive manner.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
2. Presentation Outline
What are Stem cells?
Stages of Development
The unique properties of all stem cells
Types of Stem Cells
Advantages
How stem cell therapy works?
Current stem cell therapy
Obstacles of Stem Cell Research
3. What are Stem cells?
Stem cells are “master cells “
The raw material :- from which all
of the body’s mature,
differentiated cells are made.
Stem cells give rise to brain cells,
nerve cells, heart cells, pancreatic
cells, etc.
Stem cell
Stem
cell
( unlimite
d cell
division )
Specialized cell
(e.g., white
blood cell)
5. The unique properties of all stem cells
Undifferentiated / unspecialized cells
Undifferentiated cells can differentiate to yield major specialized
cell types or organs
Self-renewal property is to maintain and repair the tissue. Thus
they have potential to replace cell tissue damaged by severe
illnesses.
7. Embryonic Type stem cells
Embryonic : derived from the inner cell mass of a blastocyst /
human embryo
Source :
1. Excess fertilized eggs from IVF (in-vitro fertilization) clinics
2. Therapeutic cloning (somatic cell nuclear transfer)
8. Adult type Stem cells
Adult : derived from mature organisms that can divide to form
more differentiated cells
- but are less versatile and more difficult to identify, isolate, and
purify.
E.g.: Stem cells have been found in the blood, bone marrow, liver,
kidney, cornea, dental pulp, brain, skin, muscle
Fetal : derived from aborted fetal tissue
Umbilical : derived from umbilical cords
- All blood cell types (red blood cells, white blood cells, and
platelets)
9. Advantages of Embryonic Stem
Cells over adult stem cells
Embryonic S.C.
“Pluripotent”
(can become any cell
types present in the
human body )
Stable. Can undergo
many cell divisions.
Easy to obtain but
blastocyst is destroyed.
Adult S.C.
“Multipotent”
(“can become many but not any”)
E.g., blood stem cells can develop into
several blood cell types, but cannot
develop into brain, kidney, or liver cells
Less Stable. Capacity for self-renewal is
limited.
Difficult to isolate in adult tissue.
10. How stem cell therapy works?
When stem cells are transplanted into the body and arrive into the
injured part, brain being targeted for tissue regeneration, the
stem cells are coming in contact with growth chemical’s (like
EGF’s , NGF’s and HGF’s )in the body. These chemicals program
the stem cells to differentiate into the tissue surrounding it.
12. Hematopoietic stem cell
transplantation (“HSCT”)
Stem cells that give rise to the lymphocytes and other cells of the
immune system, also make blood cells, are called hematopoietic
stem cells.
The process of taking stem cells from one person and putting
them into another is therefore called “ HCST”
To treat cancer patients with conditions such as leukemia and
lymphoma, sickle cell anemia,
Used in Providing a functional immune system in a person with
SCID.
13.
14. Stem cells in treating baldness
As hair follicles contain stem cells – dermal papilla
Take stem cells from existing hair follicles
Multiply them in cultures
Implant the new follicles into the scalp
15.
16. Diabetes
Diabetes patients lose the
function of their insulin-
producing beta cells of the
pancreas.
Human embryonic stem cells
may be grown in cell cultures
and stimulate to form insulin-
producing cells , that can be
transplanted into the patient
17. Corneal disease / blindness
Result in poor vision
Take stem cells from healthy eye
Grown onto contact lenses in clinical lab
Lenses are worn by the patient for a period of three weeks
Then migration of human stem cells from lens to damaged eye
and begin to repair process
Thus heals the damaged cornea and quickly improves the vision
18.
19. Parkinson disease
Caused when key brain cells that produce message carrying
chemical/neurotransmitter (dopamine) die off.
Harvesting of stem cells from patients bone marrow, fetus or any
other source
Culturing of harvested stem cells in lab conditions - to get high
concentrations of stem cells
Then purified and high concentration of stem cells are surgically
injected in the brain of patient.
22. Brain damage
Stroke and traumatic brain injury lead to cell death, characterized
by a loss of neurons and oligodendrocytes within the brain.
Healthy adult brain contain neural stem cells, these divide and act
to maintain general stem cell numbers or become progenitor cells.
27. Obstacles of Stem Cell Research
How to find the right type of stem cells?
How to put the stem cells into the right place?
Will the stem cells perform the desired function in the body?
Differentiation protocols for many cell types have not been
developed.
28. References
Odorico, J.S., Kaufman, D.S., and Thomson, J.A. (2001).
Multilineage differentiation from human embryonic stem cell
lines. Stem Cells. 19, 193 -204.
Smith, A.G. (2001). Origins and properties of mouse embryonic
stem cells. Annu. Rev. Cell. Dev. Biol.
Thomson, J.A. and Marshall, V.S. (1998). Primate embryonic
stem cells. Curr. Top. Dev. Biol. 38, 133-165.
Chandross, K.J. and Mezey, E. (2001). Plasticity of adult bone
marrow stem cells. Mattson, M.P. and Van Zant, G. eds.
(Greenwich, CT: JAI Press).
Slack, J.M. (2000). Stem cells in epithelial tissues. Science. 287,
1431-1433