5. A B R I E F H I S T O R Y
WHAT IS STEM CELL
BANKING?
Stem cell banking or preservation is the extraction,
processing and storage of stem cells, so that they may be
used for treatment in the future, when required.
Stem Cells have the amazing power to transform into
any tissue or organ in your body.
It is due to this unique characteristic that they have the
potential to treat over 80 approved life threatening
diseases, and provide numerous benefits to the baby, its
siblings and the family.
6. IT IS TO CREATE
AWARENESS AMONG THE
PEOPLE.
Stem cell banking or Umbilical cord blood banking is the process of
storing precious umbilical cord blood obtained at the time of delivery
for potential use in the future. Stem cell banking offers a healthy
future for not just your baby but the entire family.
WHAT IS STEM CELL
BANKING?
7. WHY PRESERVE
STEM CELL?
Stem cells are tiny cells with great potential & have the ability to save lives. Stem cells are
the master cells that act as basic building blocks of the human body. These cells have the
unique ability to transform into specialized cells like blood cells, brain cells, muscle cells,
bone cells and so on.
8. Stem cells are the body's raw materials — cells
from which all other cells with specialized
functions are generated. Under the right
conditions in the body or a laboratory, stem cells
divide to form more cells
called daughter cells.
These daughter cells either become new stem cells
(self-renewal) or become specialized cells
(differentiation) with a more specific function, such
as blood cells, brain cells, heart muscle cells or
bone cells. No other cell in the body has the
natural ability to generate new cell
types.
WHAT ARE STEM
CELLS?
9. Researchers and doctors hope stem cell
studies can help to : Increase understanding
of how diseases occur. By watching stem
cells mature into cells in bones,heart muscle,
nerves and other organs and tissue,
researchers and doctors may better
understand how diseases and conditions.
Generate healthy cells to replace diseased
cells(regenerative medicine).
Stem cells can be guided into becoming
specific cells that can be used to
regenerate and repair diseased or
damaged tissues in people.
WHY IS THERE SUCH AN INTEREST IN STEM CELLS?
Continue this topic on next page.
10. People who might benefit from stem cell therapies include those with spinal cord
injuries, type 1 diabetes, Parkinson's disease,amyotrophic lateral sclerosis, Alzheimer's
disease, heart disease, stroke,burns, cancer and osteoarthritis.
Stem cells may have the potential to be grown to become new tissue for use in
transplant and regenerative medicine. Researchers continue to advance the
knowledge on stem cells and their applications in transplant andregenerative
medicine.
11. Researchers have discovered several sources of stem
cells:Embryonic stem cells.
These stem cells come from embryos that are three to five
days old.
At this stage, an embryo is called a blastocyst and has about
150 cells.
These are pluripotent (ploo-RIP-uh-tunt) stem cells, meaning
they can divide into more stem cells or can become any type of
cell in the body.
This versatility allows embryonic stem cells to be used to
regenerate or repair diseased tissue and organs.
Adult stem cells
These stem cells are found in small numbers in most adult
tissues, such as bone marrow or fat.
Compared with embryonic stem cells, adult stem cells have a
more limited ability to give rise to various cells of the body.
WHERE DO STEM
CELLS COME FROM?
12. WHERE DO THESE
EMBRYOS COME FROM?
The embryos being used in embryonic stem cell
research come from eggs that were fertilized at
invitro fertilization clinics but never implanted in a
woman's uterus.
The stem cells can live and grow in special
solutions in test tubes or petri dishes in
laboratories.
The stem cells are donated with informed consent
from donors.
13. WHAT IS STEM CELL THERAPY
(REGENERATIVE MEDICINE) AND
HOW DOES IT WORK?
Stem cell therapy, also known as regenerative
medicine,promotes the repair response of
diseased, dysfunctional or injured tissue using
stem cells or their derivatives.
It is the next chapter in organ transplantation
and uses cells instead of donor organs, which
are limited in supply.
Researchers grow stem cells in a lab.
These stem cells are manipulated to
specialize into specific types of cells,
such as heart muscle cells, blood cells
or nerve cells.
Continue this topic on next page.
14. The specialized cells can then be implanted into a person.
For example, if the person has heart disease, the cells could be injected into the
heart muscle.
The healthy transplanted heart muscle cells could then contribute to repairing
defective heart muscle.
Researchers have already shown that adult bone marrow cells guided to become
heart-like cells can repair heart tissue in people, and more research is ongoing.
15. TYPES OF STEM CELL
MESENCHYMAL STEM
CELLS (MSC)
HEMATOPOIETIC STEM
CELLS (HSC)
These are found mostly in the
bone marrow but also in
peripheral blood, cord blood etc.
These cells are hematopoietic or
blood forming by nature. Thus,
they generally give rise to blood
forming cells eg. red blood cells,
white blood cells etc.
These are bone marrow populating cells
(different from HSC) that are present in the
stroma. They possess the ability to
differentiate into various cell types including,
osteocytes (bone), adipocytes (fat),
chondrocytes (cartilage), myocytes (muscle),
cardiomyocytes (cardiac muscle) and
neurons (nerves) and blood vessels, and thus
play a vital role in their regeneration as and
when required.
16. Stem cells are tiny cells with great
potential & have the ability to save
lives. Stem cells are the master
cells that act as basic building
blocks of the human body. These
cells have the unique ability to
transform into specialized cells like
blood cells, brain cells, muscle cells,
bone cells and so on.
Various factors like ageing,
injury or illness can lead to parts
of our body or its functions to be
damaged or affected. Stem cells
have the ability to both replace
or repair these affected parts by
restoring the normal function of
our body.
What Are Stem Cells? How Do Stem Cells Work?
17. Every individual has a 5% probability
of being diagnosed with a condition
treatable by stem cells. Hence, for a
family of 8 members that includes the
child, siblings, parents and
grandparents,there is a high
probability of 40% for the family
members to be diagnosed with a
condition that requires stem cells for
its treatment.
What Is The Probability Of Being Diagnosed Of A
Condition Treatable By Stem Cells?
Source:-https://www.lifecell.in/biobank/about-stem-cells
18. Today, stem cells have the ability to
treat over 80 blood related medical
conditions such as Thalassemia,
Lymphoma, Leukemia, Multiple
Myeloma, Neuroblastoma, etc.,
Over 500 clinical trials for conditions
such as Autism, Cerebral Palsy,
Stroke, Diabetes are currently
underway increasing the scope of
future treatments.
ROLE OF STEM CELLS IN HEALTHCARE
19. Categories of clinical applications
for which cord blood units have
been released from a private
newborn stem cell bank. As of
December 2018, the Cord Blood
Registry has released over 500
cord blood units for use in clinical
applications, slightly less than
20% of which were utilized in a
hematopoietic stem cell
transplant. Data are presented as
the percentage of units released
for each generalized category.
DIAGNOSIS ASSOCIATED WITH SAID INJURIES
source:-https://www.ncbi.nlm.nih.gov/
20. Types of Stem Cell Banks in India
In India, the stem cell banking services
are mainly provided by:
PRIVATELY-HELD
BANKS
GOVERNMENT-OWNED
(PUBLIC) BANKS
Community
stem cell bank
21. PRIVATE STEM CELL BANKS IN INDIA
1.LifeCell International Pvt. Ltd.
2.Reliance Life Sciences Pvt. Ltd.
3.Ree Laboratories Pvt. Ltd.
4.Regenerative Medical Services Pvt. Ltd. (BioCell)
5.Cryobanks International India Pvt. Ltd.
6.Unistem Bio Sciences Pvt. Ltd.
7.Totipotentrx Cell Therapy Pvt. Ltd.
8.Cord Life Sciences India Pvt. Ltd.
9.Narayana Hrudayalaya Tissue Bank & Stem Cells Research
Centre.
10.Cryo Save (India) Pvt. Ltd.
11.Stemcyte India Therapeutics Pvt. Ltd.
12.Indu Stem Cell Bank
13.Path Care Labs Pvt Ltd.
14.MyCord (Cellugen Biotech)
(Haryana)
(Maharashtra)
(Maharashtra)
(Maharashtra)
(Haryana)
(Haryana)
(Haryana)
(West Bengal)
(Karnataka)
(Karnataka)
(Gandhinagar,Gujarat)
(Vadodara,Gujarat)
(Andhra Pradesh)
(Haryana)
22. 1. JEEVAN STEM CELL FOUNDATION :- CHENNAI,TAMILNADU
2.THE SCHOOL OF TROPICAL MEDICINE :- KOLKATA,WEST BENGAL
PUBLIC STEM CELL BANKS IN INDIA
COMMUNITY BANKS IN INDIA
1.LifeCell International Pvt. Ltd. :- Chennai,TamilNadu
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