Spirituality refers to the human search for meaning and purpose through connection to something greater than oneself. It involves belief in a higher power and can provide strength, hope and meaning. Spiritual well-being is a feeling of being alive, purposeful and fulfilled through inner peace, compassion, gratitude and other qualities. Spiritual distress challenges one's beliefs and can result from medical issues, treatments, or situational factors like death or inability to practice spiritual rituals. Nursing care should consider patients' spiritual needs and practices around holy days, symbols, prayer, diet, healing, dress, birth and death.