This document compares the synthesis of oximes using traditional chemical methods versus ultrasonic irradiation. Oximes are important organic intermediates. The traditional method involves refluxing carbonyl compounds with hydroxylamine hydrochloride solution in ethanol as a solvent, taking 50-60 minutes and yielding 70-75%. Using ultrasonic irradiation, the same oximes were synthesized without solvent in 10-20 minutes, yielding 75-85%, which is higher than the traditional method. Yields were lowest for benzophenone oxime due to electron donation by phenyl groups decreasing carbonyl reactivity. Yields were highest for 4-chlorobenzaldehyde oxime due to electron withdrawal increasing reactivity. Thin layer chromatography confirmed the oximes produced