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International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1317
ISSN 2229-5518
IJSER © 2014
http://www.ijser.org
The Chemistry of Love
Y. Patil,
DEPARTMENT OF ENGINEERING SCIENCES
INSTITUTE OF INFORMATION TECHNOLOGY, PUNE – 411001
Abstract: In this era of hate and lust, it would be interesting to know about the chemistry behind love. The boundary line between love and lust is very
thin. To protect you from committing the misbehavior in the society culture and customs play a vital role no doubt, but it seems to the author that
knowledge of the chemistry behind love would also be helpful to behave in society. Indeed there exist biochemical activities behind every human behav-
ior. The whim, the logic, the act, the feeling everything has got involved a biochemical change pertaining to culture, circumstances and personality of
every individual.
Keywords: Lust, Attraction, Attachment, Oxytocin, Dopamine, norepinephrine, adrenaline
* Author Email for correspondence: Dr_YP@rediffmail.com
1 INTRODUCTION
IN this highly civilized society, so far, it is accepted that war is
not the solution over the quest of conquering the others but the
dialogue, and so is the love rolling all the negativity away from
the life. However, the speedy lifestyle and technological devel-
opment already have taken its toll by stealing the satisfaction
from the life of modern human beings up to considerable level.
The social transformation taking place drastically due to global-
ization has given birth to the new problems like homosexuality
and the gay relationships. Humans are coming closer than earli-
er and the relationships are becoming complex. Due to recent
developments in information technology the humans from dis-
tant regions could communicate with each other and most of
the time the communication is observed to be taking place for
appreciations. At the same time the poverty in society and the
associated problems are surfacing vigorously. The ways pro-
vided to outburst the envy and the anger through the sophisti-
cated way of sports, like Olympics and cricket, football are
found to be effective. To balance the negativity in the nature the
love is in existence since the life is on this earth surface. Even by
the social scientists and the human behavior scientists like
Maslow the need of to love and being loved is proclaimed for
the healthy society.
Love is a wonderful phenomenon that almost everyone can
relate to despite the challenging, perhaps even impossible task
of defining it or describing its many different interpretations
and implications. Curiously, the multi-dimensional construct of
love leaves many of us with pressing questions, one of which
involves the obvious notion that love must somehow be influ-
enced by internal mechanisms, but which ones and how? Logi-
cally, it has been stated that love functions biologically to ensure
the survival of a species through social attachment and repro-
duction, so it is no surprise that science has found great interest
in explaining the biology behind love. When sparks fly between
two people, we're quick to say they have "chemistry." Not eve-
ryone realizes that such couples literally have do have chemis-
try--it's what's behind those sweaty palms, the jumpy stomach,
thumping heart, and nervous jitters. Chemistry also contributes
to that warm, comfortable feeling you get from being with a
longtime partner.
The following text elaborates the role of Chemistry behind love
and the precautions to be followed in the love laboratory i.e.
life.
All in the chemical family
We all have “chemical families” associated with dopamine, ser-
otonin, testosterone, and estrogen. People choose partners with
chemicals that complement their own. For example, a person
with a high amount of estrogen may be attracted to a high-
testosterone type.
Psychology plays a role, too. Our choice of a mate is partly dic-
tated by a “love map,” an unconscious list of traits we want in
an ideal partner that we construct during our childhood. We get
used to our father’s sense of humor or our mother’s brand of
affection and use this to build our list. When we meet a poten-
tial partner, we consciously and unconsciously determine if that
person is right for us. “We often do this in less than three
minutes,” Fisher says.
The science of love
And when it comes to sniffing around for love, you may have
more in common with Fido than you think. Martie Haselton,
PhD, with the communication studies and psychology depart-
ments at the University of California, Los Angeles, has been
studying major histocompatibility complex, or MHC, a set of
genes involved in immunity that might play a role in mating by
way of our sense of smell.
“People rate the body odors of people with MHC genes dissimi-
lar from their own as more attractive,” Haselton says. Also, re-
search shows that children who inherit different MHC from
each of their parents have broader immunity.
IJSER
International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1318
ISSN 2229-5518
IJSER © 2014
http://www.ijser.org
If it’s all chemical, do we have any control over the process?
Researchers say you can trigger your body’s chemistry to keep
love alive by:
-Keeping it fresh Novelty drives up dopamine in the brain,
this can help sustain romantic love. Go to the movies in a differ-
ent part of town or head out for the evening without knowing
where you’ll end up.
-Keeping in touch Any kind of touching, such as holding
hands or playing footsie, can drive up oxytocin. Sometimes
called the hormone of love, oxytocin is associated with attach-
ment.
-Keeping it happening Creating interests in day to day activ-
ities by adopting innovative ways of love making. If you’ve
gotten out of the habit, work on getting back into it -- even if
you need to seek professional help.
The most well-known love-related chemical is phenylethyla-
mine -- or "PEA" -- a naturally occurring trace ammine in the
brain. PEA is a natural amphetamine, like the drug, and can
cause similar stimulation. This natural upper contributes to that
kick-up-your-heels, on-top-of-the-world feeling that attraction
can bring, and gives you the energy to stay up all night talking
to a new love. Sometimes this energy translates into the triple-
espresso jitters; other times it simply keeps you wide-eyed and
alert long past the time when you'd usually be yawning.
Feeling Dopey
You can also get a non-romantic dose of PEA from high-
intensity activities like skydiving, or by eating chocolate. Ac-
cording to Chocolate.org, chocolate contains small amounts of
our love drug, PEA. That might be why some people use choco-
late as "comfort food," getting the same warm, relaxed feeling
from chocolate as others do from Mom's chicken soup.
One of the substances released by PEA is the neurochemical
dopamine. A recent study done at Emory University shows that
female vole (small rodents) choose their mates in response to
dopamine being released in their brains. When injected with
dopamine in a male vole's presence, the female will pick him
out of a crowd later. Our love food, chocolate, also elevates lev-
els of dopamine in the brain.
Figure: Schematic presentation for different parts of brain
which remains activated during activity of love
In turn, Dopamine stimulates the production of oxytocin, some-
times known as "the cuddle chemical." Oxytocin is best known
for its role in mothering, stimulating contractions during labor
and aiding with breast feeding. According to BirthPsycholo-
gy.com scientists now think that both genders release this nur-
turing hormone when touching and cuddling, with the oxytocin
level peaking during orgasm.
Another euphoria-inducing chemical in your brain, norepi-
nephrine, stimulates the production of adrenaline and makes
your blood pressure soar when near the person you're attracted
to. That's why you might experience a pounding heart or
sweaty palms when you see someone you've got the hots for.
There are three stages of love: lust, attraction, and attachment.
Each stage is driven by a set of different hormones and chemi-
cals. Lust, the first stage of love, is driven by the sex hormones
testosterone and estrogen. From puberty onward, the amount of
testosterone and estrogen released increases immensely. The
testosterone level in a teenage boy’s body is the same level as an
adult’s after drinking four to five shots of strong liquor. The
feeling of lust is caused by the body’s production of testosterone
and estrogen, which peaks from puberty onward.
The next stage of love is attraction, when one can focus on little
or nothing else other than the person he or she is attracted to.
This stage is a result of a process under three neurotransmitters:
dopamine, norepinephrine and serotonin. Norepinephrine is
similar to adrenaline, which causes effects like a racing heart,
sweaty palms, and flushed skin. Sound familiar? Yes, this is
what happens when a person unexpectedly bumps into his or
her new crush. Besides norepinephrine, dopamine plays an im-
portant role in the attraction stage. Dopamine is thought to be
the pleasure chemical that produces the feeling of bliss. Re-
searchers have used functional magnetic resonance imaging
(fMRI) to observe people’s brains when they are looking at a
picture of their object of affection. The scans showed increased
blood flow in areas concentrated with dopamine receptors,
which are associated with states of euphoria, craving, and ad-
diction.
Together, the combination of norepinephrine with dopamine
produces elation, intense energy, sleeplessness, loss of attention,
and exquisite delight from small details.
The third stage of love is attachment. This stage allows a couple
to bond for a longer period of time. Two important chemicals
that are responsible for this stage are oxytocin and vasopressin.
According to researchers at University of California, San Fran-
cisco, the hormone oxytocin has been shown to be “associated
with the ability to maintain healthy interpersonal relationships
and healthy psychological boundaries with other people.” Vas-
opressin, an anti-diuretic hormone, is another chemical that has
IJSER
International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1319
ISSN 2229-5518
IJSER © 2014
http://www.ijser.org
an effect on long-term relationships. It is believed that oxytocin
and vasopressin interrupt the dopamine and norepinephrine
pathways, which is a possible explanation of why passionate
love fades as attachment grows within a couple.
What The Brain Tells the Body
How do our emotions get translated into physical sensations? A
U.S. News and World Report article explains the importance of
the vagus, a nerve that threads through your whole body. It
transports signals from your brain to your organs, "setting the
heart pounding, making the stomach do flip-flops, and of
course, lighting the loins on fire." Everyone knows that jumpy,
sort of sick feeling in your stomach.
Tennov's group also reported "intrusive thinking," where it
seems like your brain is fixated on the object of your affection.
When your heart rules your head, there's actually one part of
your brain running the other: the cortex is the area of your brain
that controls logical thinking, while emotions are processed by
the limbic system. When too many happy chemicals like PEA
and dopamine flood your brain, they head straight for the lim-
bic system.
When The Honeymoon's Over
Some scientists believe that after a certain period, from 18
months to 4 years, one's body gets used to these love stimulants.
After building up a tolerance to uppers like PEA, passionate
romances can cool into what Helen Fisher, author of "Anatomy
of Love" calls "attachment." In this phase of the relationship,
your brain produces endorphins, brain opiates more like mor-
phine than speed. "Unlike PEA," says Fisher, "they calm the
mind, kill pain, and reduce anxiety." So what some people call
"separation anxiety" might actually be a form of drug with-
drawal.
The idea that the "honeymoon period" of a relationship is fueled
by different brain chemistry than what is present during the
mellower years that come later might explain why some people
can't seem to hold long-term relationships: they prefer the rev-
ving-up affects of brain amphetamines to the pain-killing effects
of endorphins.
"Divorce rates peak around the fourth year of marriage," says
Charles Panati in his book "Sexy Origins and Intimate Things."
"The initial 'highs' of love have lost their chemical underpin-
nings Marilyn Monroe's classic film "The Seven Year Itch"
should be retitled 'The Four Year Itch."
Lynn Harris, co-creator of BreakupGirl.com wonders if it's the
other way around. "Relationships take work. They just do. And
people get lazy after a while," she says. "So do they get lazy be-
cause they're getting immune to the chemicals, or do they get
lazy because they just do...which triggers a decline in the chemi-
cals?"
In the end, even hard-core scientists agree that chemistry isn't
everything. Culture, circumstances, personality, and scores of
other variables help decide who turns your head and who
leaves you cold. So don't try to reproduce that lovin' feeling in a
basement chemistry lab--but do try your best to enjoy the natu-
ral highs that life gives you.
Acknowledgement: The author is thankful to all the lovers
worldwide, as they keep the love-vine growing continuously.
Also the authors whose literature is referred to cast this article
are acknowledged humbly.
References:
[1] Maslow A.H. (1943). A theory of human motivation. Psychological Review,
50(4),370–96.
[2] Doheny,Kathleen.(2008). Love onthe brain.FromWebMD Special Report:
[3] http://www.webmd.com/sex-relationships/modern-love-8/biology-of-love
[4] Esch, Tobias, Stefano, George B. (2005). Neurobiology of love. From Neuro-
endocrinology Letters:
[5] http://www.nel.edu/pdf_/26_3/260305R01_15990719_Esch--Stefano_.pdf
[6] Fisher, Helen. (2004). Your brain in love. From Time Magazine:
http://www.time.com/time/printout/0,8816,993160,00.html
[7] McManamy, John. (2008). The Brain in love and lust.
http://www.mcmanweb.com/love_lust.html
[8] Zeki, S.(2007).The Neurobiology of love. FromFEBS Letters:
[9] http://linkinghub.elsevier.com/retrieve/pii/S0014579307004875
[10] Links:
[1] http://www.webmd.com/sex-relationships/moern-love-8/biology-of-
love?page=2
[2] http://www.nel.edu/pdf_/26_3/260305R01_15990719_Esch--
Stefano_.pdf
[3] http://www.time.com/time/printout/0,8816,993160,00.html
[4] http://www.mcmanweb.com/love_lust.html
[5] http://linkinghub.elsevier.com/retrieve/pii/S0014579307004875
[6] http://serendip.brynmawr.edu/exchange/courses/NBSseminar/s08
[7] http://www.romancestuck.com/articles/chemistryoflove.htm
IJSER

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Researchpaper the chemistry-of-love

  • 1. International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1317 ISSN 2229-5518 IJSER © 2014 http://www.ijser.org The Chemistry of Love Y. Patil, DEPARTMENT OF ENGINEERING SCIENCES INSTITUTE OF INFORMATION TECHNOLOGY, PUNE – 411001 Abstract: In this era of hate and lust, it would be interesting to know about the chemistry behind love. The boundary line between love and lust is very thin. To protect you from committing the misbehavior in the society culture and customs play a vital role no doubt, but it seems to the author that knowledge of the chemistry behind love would also be helpful to behave in society. Indeed there exist biochemical activities behind every human behav- ior. The whim, the logic, the act, the feeling everything has got involved a biochemical change pertaining to culture, circumstances and personality of every individual. Keywords: Lust, Attraction, Attachment, Oxytocin, Dopamine, norepinephrine, adrenaline * Author Email for correspondence: Dr_YP@rediffmail.com 1 INTRODUCTION IN this highly civilized society, so far, it is accepted that war is not the solution over the quest of conquering the others but the dialogue, and so is the love rolling all the negativity away from the life. However, the speedy lifestyle and technological devel- opment already have taken its toll by stealing the satisfaction from the life of modern human beings up to considerable level. The social transformation taking place drastically due to global- ization has given birth to the new problems like homosexuality and the gay relationships. Humans are coming closer than earli- er and the relationships are becoming complex. Due to recent developments in information technology the humans from dis- tant regions could communicate with each other and most of the time the communication is observed to be taking place for appreciations. At the same time the poverty in society and the associated problems are surfacing vigorously. The ways pro- vided to outburst the envy and the anger through the sophisti- cated way of sports, like Olympics and cricket, football are found to be effective. To balance the negativity in the nature the love is in existence since the life is on this earth surface. Even by the social scientists and the human behavior scientists like Maslow the need of to love and being loved is proclaimed for the healthy society. Love is a wonderful phenomenon that almost everyone can relate to despite the challenging, perhaps even impossible task of defining it or describing its many different interpretations and implications. Curiously, the multi-dimensional construct of love leaves many of us with pressing questions, one of which involves the obvious notion that love must somehow be influ- enced by internal mechanisms, but which ones and how? Logi- cally, it has been stated that love functions biologically to ensure the survival of a species through social attachment and repro- duction, so it is no surprise that science has found great interest in explaining the biology behind love. When sparks fly between two people, we're quick to say they have "chemistry." Not eve- ryone realizes that such couples literally have do have chemis- try--it's what's behind those sweaty palms, the jumpy stomach, thumping heart, and nervous jitters. Chemistry also contributes to that warm, comfortable feeling you get from being with a longtime partner. The following text elaborates the role of Chemistry behind love and the precautions to be followed in the love laboratory i.e. life. All in the chemical family We all have “chemical families” associated with dopamine, ser- otonin, testosterone, and estrogen. People choose partners with chemicals that complement their own. For example, a person with a high amount of estrogen may be attracted to a high- testosterone type. Psychology plays a role, too. Our choice of a mate is partly dic- tated by a “love map,” an unconscious list of traits we want in an ideal partner that we construct during our childhood. We get used to our father’s sense of humor or our mother’s brand of affection and use this to build our list. When we meet a poten- tial partner, we consciously and unconsciously determine if that person is right for us. “We often do this in less than three minutes,” Fisher says. The science of love And when it comes to sniffing around for love, you may have more in common with Fido than you think. Martie Haselton, PhD, with the communication studies and psychology depart- ments at the University of California, Los Angeles, has been studying major histocompatibility complex, or MHC, a set of genes involved in immunity that might play a role in mating by way of our sense of smell. “People rate the body odors of people with MHC genes dissimi- lar from their own as more attractive,” Haselton says. Also, re- search shows that children who inherit different MHC from each of their parents have broader immunity. IJSER
  • 2. International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1318 ISSN 2229-5518 IJSER © 2014 http://www.ijser.org If it’s all chemical, do we have any control over the process? Researchers say you can trigger your body’s chemistry to keep love alive by: -Keeping it fresh Novelty drives up dopamine in the brain, this can help sustain romantic love. Go to the movies in a differ- ent part of town or head out for the evening without knowing where you’ll end up. -Keeping in touch Any kind of touching, such as holding hands or playing footsie, can drive up oxytocin. Sometimes called the hormone of love, oxytocin is associated with attach- ment. -Keeping it happening Creating interests in day to day activ- ities by adopting innovative ways of love making. If you’ve gotten out of the habit, work on getting back into it -- even if you need to seek professional help. The most well-known love-related chemical is phenylethyla- mine -- or "PEA" -- a naturally occurring trace ammine in the brain. PEA is a natural amphetamine, like the drug, and can cause similar stimulation. This natural upper contributes to that kick-up-your-heels, on-top-of-the-world feeling that attraction can bring, and gives you the energy to stay up all night talking to a new love. Sometimes this energy translates into the triple- espresso jitters; other times it simply keeps you wide-eyed and alert long past the time when you'd usually be yawning. Feeling Dopey You can also get a non-romantic dose of PEA from high- intensity activities like skydiving, or by eating chocolate. Ac- cording to Chocolate.org, chocolate contains small amounts of our love drug, PEA. That might be why some people use choco- late as "comfort food," getting the same warm, relaxed feeling from chocolate as others do from Mom's chicken soup. One of the substances released by PEA is the neurochemical dopamine. A recent study done at Emory University shows that female vole (small rodents) choose their mates in response to dopamine being released in their brains. When injected with dopamine in a male vole's presence, the female will pick him out of a crowd later. Our love food, chocolate, also elevates lev- els of dopamine in the brain. Figure: Schematic presentation for different parts of brain which remains activated during activity of love In turn, Dopamine stimulates the production of oxytocin, some- times known as "the cuddle chemical." Oxytocin is best known for its role in mothering, stimulating contractions during labor and aiding with breast feeding. According to BirthPsycholo- gy.com scientists now think that both genders release this nur- turing hormone when touching and cuddling, with the oxytocin level peaking during orgasm. Another euphoria-inducing chemical in your brain, norepi- nephrine, stimulates the production of adrenaline and makes your blood pressure soar when near the person you're attracted to. That's why you might experience a pounding heart or sweaty palms when you see someone you've got the hots for. There are three stages of love: lust, attraction, and attachment. Each stage is driven by a set of different hormones and chemi- cals. Lust, the first stage of love, is driven by the sex hormones testosterone and estrogen. From puberty onward, the amount of testosterone and estrogen released increases immensely. The testosterone level in a teenage boy’s body is the same level as an adult’s after drinking four to five shots of strong liquor. The feeling of lust is caused by the body’s production of testosterone and estrogen, which peaks from puberty onward. The next stage of love is attraction, when one can focus on little or nothing else other than the person he or she is attracted to. This stage is a result of a process under three neurotransmitters: dopamine, norepinephrine and serotonin. Norepinephrine is similar to adrenaline, which causes effects like a racing heart, sweaty palms, and flushed skin. Sound familiar? Yes, this is what happens when a person unexpectedly bumps into his or her new crush. Besides norepinephrine, dopamine plays an im- portant role in the attraction stage. Dopamine is thought to be the pleasure chemical that produces the feeling of bliss. Re- searchers have used functional magnetic resonance imaging (fMRI) to observe people’s brains when they are looking at a picture of their object of affection. The scans showed increased blood flow in areas concentrated with dopamine receptors, which are associated with states of euphoria, craving, and ad- diction. Together, the combination of norepinephrine with dopamine produces elation, intense energy, sleeplessness, loss of attention, and exquisite delight from small details. The third stage of love is attachment. This stage allows a couple to bond for a longer period of time. Two important chemicals that are responsible for this stage are oxytocin and vasopressin. According to researchers at University of California, San Fran- cisco, the hormone oxytocin has been shown to be “associated with the ability to maintain healthy interpersonal relationships and healthy psychological boundaries with other people.” Vas- opressin, an anti-diuretic hormone, is another chemical that has IJSER
  • 3. International Journal of Scientific & Engineering Research, Volume 5, Issue 4, April-2014 1319 ISSN 2229-5518 IJSER © 2014 http://www.ijser.org an effect on long-term relationships. It is believed that oxytocin and vasopressin interrupt the dopamine and norepinephrine pathways, which is a possible explanation of why passionate love fades as attachment grows within a couple. What The Brain Tells the Body How do our emotions get translated into physical sensations? A U.S. News and World Report article explains the importance of the vagus, a nerve that threads through your whole body. It transports signals from your brain to your organs, "setting the heart pounding, making the stomach do flip-flops, and of course, lighting the loins on fire." Everyone knows that jumpy, sort of sick feeling in your stomach. Tennov's group also reported "intrusive thinking," where it seems like your brain is fixated on the object of your affection. When your heart rules your head, there's actually one part of your brain running the other: the cortex is the area of your brain that controls logical thinking, while emotions are processed by the limbic system. When too many happy chemicals like PEA and dopamine flood your brain, they head straight for the lim- bic system. When The Honeymoon's Over Some scientists believe that after a certain period, from 18 months to 4 years, one's body gets used to these love stimulants. After building up a tolerance to uppers like PEA, passionate romances can cool into what Helen Fisher, author of "Anatomy of Love" calls "attachment." In this phase of the relationship, your brain produces endorphins, brain opiates more like mor- phine than speed. "Unlike PEA," says Fisher, "they calm the mind, kill pain, and reduce anxiety." So what some people call "separation anxiety" might actually be a form of drug with- drawal. The idea that the "honeymoon period" of a relationship is fueled by different brain chemistry than what is present during the mellower years that come later might explain why some people can't seem to hold long-term relationships: they prefer the rev- ving-up affects of brain amphetamines to the pain-killing effects of endorphins. "Divorce rates peak around the fourth year of marriage," says Charles Panati in his book "Sexy Origins and Intimate Things." "The initial 'highs' of love have lost their chemical underpin- nings Marilyn Monroe's classic film "The Seven Year Itch" should be retitled 'The Four Year Itch." Lynn Harris, co-creator of BreakupGirl.com wonders if it's the other way around. "Relationships take work. They just do. And people get lazy after a while," she says. "So do they get lazy be- cause they're getting immune to the chemicals, or do they get lazy because they just do...which triggers a decline in the chemi- cals?" In the end, even hard-core scientists agree that chemistry isn't everything. Culture, circumstances, personality, and scores of other variables help decide who turns your head and who leaves you cold. So don't try to reproduce that lovin' feeling in a basement chemistry lab--but do try your best to enjoy the natu- ral highs that life gives you. Acknowledgement: The author is thankful to all the lovers worldwide, as they keep the love-vine growing continuously. Also the authors whose literature is referred to cast this article are acknowledged humbly. References: [1] Maslow A.H. (1943). A theory of human motivation. Psychological Review, 50(4),370–96. [2] Doheny,Kathleen.(2008). Love onthe brain.FromWebMD Special Report: [3] http://www.webmd.com/sex-relationships/modern-love-8/biology-of-love [4] Esch, Tobias, Stefano, George B. (2005). Neurobiology of love. From Neuro- endocrinology Letters: [5] http://www.nel.edu/pdf_/26_3/260305R01_15990719_Esch--Stefano_.pdf [6] Fisher, Helen. (2004). Your brain in love. From Time Magazine: http://www.time.com/time/printout/0,8816,993160,00.html [7] McManamy, John. (2008). The Brain in love and lust. http://www.mcmanweb.com/love_lust.html [8] Zeki, S.(2007).The Neurobiology of love. FromFEBS Letters: [9] http://linkinghub.elsevier.com/retrieve/pii/S0014579307004875 [10] Links: [1] http://www.webmd.com/sex-relationships/moern-love-8/biology-of- love?page=2 [2] http://www.nel.edu/pdf_/26_3/260305R01_15990719_Esch-- Stefano_.pdf [3] http://www.time.com/time/printout/0,8816,993160,00.html [4] http://www.mcmanweb.com/love_lust.html [5] http://linkinghub.elsevier.com/retrieve/pii/S0014579307004875 [6] http://serendip.brynmawr.edu/exchange/courses/NBSseminar/s08 [7] http://www.romancestuck.com/articles/chemistryoflove.htm IJSER