Sepsis and septic shock guidelines
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This document discusses sepsis and septic shock. Sepsis is a life-threatening organ dysfunction caused by a dysregulated response to infection, while septic shock involves persistent hypotension and elevated lactate levels despite fluid resuscitation. Risk factors include diabetes, cirrhosis and leukopenia. Treatment involves restoring perfusion with fluids and vasopressors, administering broad-spectrum antibiotics, controlling the infection source, and providing supportive care such as glucose control and corticosteroids. Early recognition and treatment are key to improved survival outcomes.
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Sepsis and septic shock
Sepsis is a systemic inflammatory response to infection that can progress to severe sepsis and septic shock. Severe sepsis is defined as sepsis with organ dysfunction or hypotension, while septic shock involves hypotension despite fluid resuscitation and signs of hypoperfusion. Treatment involves identifying and treating the infection source, administering IV fluids and vasopressors to restore perfusion, and giving broad-spectrum antibiotics. The goal is to reverse hypoperfusion and prevent further organ damage.
Sepsis
This document provides guidelines for the management of severe sepsis and septic shock. It discusses definitions of sepsis, systemic inflammatory response syndrome, and septic shock. It outlines initial resuscitation goals including fluid resuscitation, vasopressors, inotropic therapy, and goals for central venous pressure, mean arterial pressure, urine output, and central venous or mixed venous oxygen saturation. It provides recommendations on antibiotic therapy, source control, steroids, activated protein C, transfusion thresholds, glucose control, renal replacement therapy, stress ulcer prophylaxis, and implementing a sepsis resuscitation bundle.
Sepsis, Septic Shock and Surviving Sepsis Guidelines
This document provides guidelines for treating sepsis, septic shock, and surviving sepsis. It defines terms like SIRS, sepsis, severe sepsis, and septic shock. The key pathophysiology of organ injury in sepsis is described. Treatment protocols like the Sepsis Six and Surviving Sepsis Campaign aim to rapidly identify and treat sepsis patients. Initial resuscitation focuses on fluid administration, vasopressors, inotropes, and lactate normalization. Antimicrobial therapy within 1 hour is critical. Source control through drainage or surgery may be needed. Overall the document provides clinical definitions and guidelines for diagnosis and management of sepsis.
Sepsis and septic shock
1. The document outlines new definitions and guidelines for diagnosing and managing sepsis and septic shock according to the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
2. Key changes include removing SIRS criteria and defining sepsis as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Septic shock requires vasopressors to maintain blood pressure and elevated lactate levels.
3. Management guidelines cover initial patient assessment, diagnostic testing, antimicrobial therapy, fluid resuscitation, vasopressors, corticosteroids, mechanical ventilation, glucose control, nutrition, and thromboembolism prophylaxis
What is new in sepsis
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection.The definition of sepsis was updated in 2016 following publication of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). This recommended that organ dysfunction should be defined using the Sequential (or Sepsis-related) Organ Failure Assessment (SOFA) criteria or the "quick" (q)SOFA criteria.
Management of severe sepsis & septic shock f
1) The document defines sepsis, severe sepsis, and septic shock and provides diagnostic criteria. It discusses initial resuscitation goals for the first 6 hours including fluid administration, vasopressors, and ScvO2/lactate monitoring.
2) Management recommendations are provided for antimicrobial therapy, source control, fluid therapy, vasopressors, blood products, glucose control, and other areas. Bundle elements are outlined to be completed within 3 and 6 hours of diagnosis.
3) Guidelines include level of evidence ratings and discuss evidence from studies on topics like fluid resuscitation, vasopressor use, and ventilator management for patients with severe sepsis or septic shock.
sepsis
A 73-year-old woman presented with symptoms of weakness, cough, and fever. On examination, she was somnolent with a low-grade fever, rapid heart rate and breathing, low blood pressure, and crackles in her right lung. Based on her symptoms and exam findings meeting two SIRS criteria, the most likely diagnosis is systemic inflammatory response syndrome (SIRS) due to a potential infection such as pneumonia. Sepsis occurs when SIRS is caused by a confirmed or suspected infection and can progress to septic shock, organ dysfunction, and death if not properly treated.
Sepsis update 2021
Update yourself on surviving sepsis 2021 updated guideline. this gives a brief outline on new recommendations to follow..
Recommended
Sepsis and septic shock
Sepsis is a systemic inflammatory response to infection that can progress to severe sepsis and septic shock. Severe sepsis is defined as sepsis with organ dysfunction or hypotension, while septic shock involves hypotension despite fluid resuscitation and signs of hypoperfusion. Treatment involves identifying and treating the infection source, administering IV fluids and vasopressors to restore perfusion, and giving broad-spectrum antibiotics. The goal is to reverse hypoperfusion and prevent further organ damage.
Sepsis
This document provides guidelines for the management of severe sepsis and septic shock. It discusses definitions of sepsis, systemic inflammatory response syndrome, and septic shock. It outlines initial resuscitation goals including fluid resuscitation, vasopressors, inotropic therapy, and goals for central venous pressure, mean arterial pressure, urine output, and central venous or mixed venous oxygen saturation. It provides recommendations on antibiotic therapy, source control, steroids, activated protein C, transfusion thresholds, glucose control, renal replacement therapy, stress ulcer prophylaxis, and implementing a sepsis resuscitation bundle.
Sepsis, Septic Shock and Surviving Sepsis Guidelines
This document provides guidelines for treating sepsis, septic shock, and surviving sepsis. It defines terms like SIRS, sepsis, severe sepsis, and septic shock. The key pathophysiology of organ injury in sepsis is described. Treatment protocols like the Sepsis Six and Surviving Sepsis Campaign aim to rapidly identify and treat sepsis patients. Initial resuscitation focuses on fluid administration, vasopressors, inotropes, and lactate normalization. Antimicrobial therapy within 1 hour is critical. Source control through drainage or surgery may be needed. Overall the document provides clinical definitions and guidelines for diagnosis and management of sepsis.
Sepsis and septic shock
1. The document outlines new definitions and guidelines for diagnosing and managing sepsis and septic shock according to the Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.
2. Key changes include removing SIRS criteria and defining sepsis as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Septic shock requires vasopressors to maintain blood pressure and elevated lactate levels.
3. Management guidelines cover initial patient assessment, diagnostic testing, antimicrobial therapy, fluid resuscitation, vasopressors, corticosteroids, mechanical ventilation, glucose control, nutrition, and thromboembolism prophylaxis
What is new in sepsis
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to an infection.The definition of sepsis was updated in 2016 following publication of the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). This recommended that organ dysfunction should be defined using the Sequential (or Sepsis-related) Organ Failure Assessment (SOFA) criteria or the "quick" (q)SOFA criteria.
Management of severe sepsis & septic shock f
1) The document defines sepsis, severe sepsis, and septic shock and provides diagnostic criteria. It discusses initial resuscitation goals for the first 6 hours including fluid administration, vasopressors, and ScvO2/lactate monitoring.
2) Management recommendations are provided for antimicrobial therapy, source control, fluid therapy, vasopressors, blood products, glucose control, and other areas. Bundle elements are outlined to be completed within 3 and 6 hours of diagnosis.
3) Guidelines include level of evidence ratings and discuss evidence from studies on topics like fluid resuscitation, vasopressor use, and ventilator management for patients with severe sepsis or septic shock.
sepsis
A 73-year-old woman presented with symptoms of weakness, cough, and fever. On examination, she was somnolent with a low-grade fever, rapid heart rate and breathing, low blood pressure, and crackles in her right lung. Based on her symptoms and exam findings meeting two SIRS criteria, the most likely diagnosis is systemic inflammatory response syndrome (SIRS) due to a potential infection such as pneumonia. Sepsis occurs when SIRS is caused by a confirmed or suspected infection and can progress to septic shock, organ dysfunction, and death if not properly treated.
Sepsis update 2021
Update yourself on surviving sepsis 2021 updated guideline. this gives a brief outline on new recommendations to follow..
Sepsis and septic shock
Sepsis and septic shock result from a dysregulated host response to infection that leads to organ dysfunction. Management involves immediate resuscitation within 1 hour with IV fluids, antibiotics, and vasopressors if needed. Ongoing care includes source control, frequent reassessment of volume status, and supportive care such as mechanical ventilation and nutrition. The goals are to treat the underlying infection while supporting failing organs until the host response normalizes. Sepsis affects millions worldwide and requires swift treatment to prevent progression to septic shock and death.
Septic shock
This document discusses septic shock, its definitions, signs, symptoms, causes, risk factors, pathophysiology, management, and treatment. It defines septic shock as persisting hypotension requiring vasopressors to maintain blood pressure and a serum lactate above 2 mmol/L despite fluid resuscitation. Management involves early antibiotic therapy, source control, fluid resuscitation, vasopressor support, and organ support. The key goals are starting appropriate antibiotics quickly, resuscitating from shock, identifying and treating the infection source, and maintaining organ function.
Sepsis
Sepsis is a life-threatening condition caused by the body's response to an infection. It can progress to septic shock, which has a high mortality rate. The initial management of sepsis involves rapid fluid resuscitation, administration of broad-spectrum antibiotics within 1 hour, and measuring serum lactate levels and obtaining blood cultures. Implementation of a code sepsis protocol can improve compliance with treatment guidelines and reduce mortality rates by facilitating early goal-directed therapy. De-escalation of antimicrobial therapy based on the patient's clinical response is important to prevent overuse of antibiotics.
New definition of sepsis... sepsis 3
The document discusses proposed changes to the definitions of sepsis, septic shock, and related terms based on recent evidence and consensus guidelines. It summarizes the new definitions as follows:
1) Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, assessed using a SOFA score ≥ 2 points.
2) Septic shock involves profound circulatory and cellular abnormalities indicated by persisting hypotension requiring vasopressors and serum lactate >2mmol/L, despite adequate fluid resuscitation.
3) Terms like "severe sepsis" are removed, and quick SOFA (qSOFA) criteria are suggested for evaluating sepsis outside the ICU.
Septicemia international management guideline
This document provides guidelines for the management of sepsis and septic shock. It defines key terms like sepsis, severe sepsis, septic shock, and systemic inflammatory response syndrome. It outlines variables for diagnosis and assessing organ dysfunction. It recommends initial resuscitation goals within 3-6 hours including measuring lactate, administering antibiotics and fluids, and applying vasopressors if needed. It provides guidelines for diagnosis, source control, antibiotic therapy, fluid therapy, vasopressor use, and other supportive treatments. Recommendations are evidence-based with assigned grade levels.
Sepsis
Sepsis and septic shock are life-threatening conditions caused by the body's response to infection. Sepsis occurs when infection leads to organ dysfunction, while septic shock involves profound circulatory and cellular abnormalities that greatly increase the risk of death. Risk factors include older age, pregnancy, chronic diseases, and weak immune systems. Common causes are infections of the lungs, digestive tract, urinary system, and bloodstream. Signs and symptoms include inflammation, low blood pressure, organ dysfunction, tissue hypoperfusion, and coagulation abnormalities. Treatment involves antibiotics, IV fluids, vasopressors, supportive care, and surgery to remove the infection source.
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Sepsis
Enumerates the latest advancements in the management of sepsis and the search into its pathophysiology.
Sepsis and septic shock
Sepsis is a life-threatening organ dysfunction caused by a dysregulated response to infection. Septic shock is a more severe form of sepsis involving significantly decreased blood pressure and elevated lactate levels despite fluid resuscitation. Key factors in the pathophysiology of sepsis and septic shock include vasodilation, decreased peripheral resistance, distributive shock, and potential coagulopathy and organ dysfunction. Early recognition and treatment through IV fluids, vasopressors, antibiotics, source control and supportive care are important for improved survival.
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This document discusses sepsis diagnosis and management. It provides historical context on defining sepsis and outlines diagnostic criteria. Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated response to infection. Common infections that cause sepsis include those of the lung, abdomen, and urine. Management involves initial resuscitation, administering appropriate intravenous antibiotics within 1 hour, and controlling the infection source when possible through procedures like drainage or debridement. Vasopressors, fluid resuscitation, and inotropes may be needed to support blood pressure and organ perfusion.
Sepsis And Septic Shock
The document discusses concepts related to sepsis, severe sepsis, and septic shock. It provides statistics on the incidence and mortality of these conditions. It also describes the pathophysiology of sepsis, including the roles of inflammation, coagulation abnormalities, and hemodynamic changes. Potential mediators such as cytokines, nitric oxide, and endotoxin are examined in the development of septic shock.
Surviving Sepsis Guidelines Updated
The document summarizes updated guidelines from the 41th Society of Critical Care Medicine Meeting for treating sepsis. Key changes include recommending crystalloids like saline for initial fluid resuscitation; using norepinephrine as the first choice vasopressor; considering corticosteroids for refractory shock; using higher PEEP and recruitment maneuvers for ARDS; and considering procalcitonin to determine if antibiotics can be stopped. The Surviving Sepsis guidelines were previously criticized for being funded primarily by Eli Lilly without disclosure.
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Sepsis and septic shock are life-threatening medical emergencies caused by dysregulated host response to infection leading to organ dysfunction. Management involves immediate evaluation and treatment, initial fluid resuscitation, early goal directed therapy including antibiotics and source control. Vasopressors, corticosteroids, glucose control, ventilation and DVT prophylaxis are also important supportive therapies to treat sepsis and prevent complications. The goal is to treat the infection and reverse the associated organ dysfunction.
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Septic shock is a life-threatening condition that arises when sepsis leads to dangerously low blood pressure and problems in organ function. It results from an infection that causes changes throughout the body. Early recognition and treatment are important, including administering antibiotics within an hour, aggressive fluid resuscitation, and monitoring for organ dysfunction. Goals of management are restoring blood pressure, reversing signs of low perfusion, and treating the underlying infection while avoiding additional organ injury.
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This document discusses definitions, diagnosis, and management of sepsis. It covers:
- The history and updates of sepsis definitions from 1991 to the current Sepsis-3 criteria in 2016. Sepsis-3 aims to identify sicker patients but relies on subjective criteria.
- Guidelines for sepsis management, including initial resuscitation bundles from the Surviving Sepsis Campaign and controversies around early goal-directed therapy. Personalized approaches are now recommended.
- Ongoing research on various sepsis treatments, including fluids, vasopressors, steroids, antibiotics, and other emerging therapies, with mixed evidence on best practices. Rapid treatment remains important but a personalized approach is needed.
Sepsis and septic shock guidelines 2021. part 1
1. Sepsis is a critical imbalance between oxygen supply and demand that can affect any system. Serum lactate levels rise in response to tissue hypoxia and higher levels correlate with poorer outcomes.
2. Guidelines recommend screening high-risk patients for sepsis and using standard treatment protocols. Blood lactate should be measured in suspected cases and treatment begun immediately.
3. Fluid resuscitation of at least 30mL/kg should begin within 3 hours, guided by dynamic measures over static parameters alone. Antimicrobial therapy should also begin immediately or within 1-3 hours depending on risk level and presence of shock.
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Sepsis and septic shock
Sepsis and septic shock result from a dysregulated host response to infection that leads to organ dysfunction. Management involves immediate resuscitation within 1 hour with IV fluids, antibiotics, and vasopressors if needed. Ongoing care includes source control, frequent reassessment of volume status, and supportive care such as mechanical ventilation and nutrition. The goals are to treat the underlying infection while supporting failing organs until the host response normalizes. Sepsis affects millions worldwide and requires swift treatment to prevent progression to septic shock and death.
Septic shock
This document discusses septic shock, its definitions, signs, symptoms, causes, risk factors, pathophysiology, management, and treatment. It defines septic shock as persisting hypotension requiring vasopressors to maintain blood pressure and a serum lactate above 2 mmol/L despite fluid resuscitation. Management involves early antibiotic therapy, source control, fluid resuscitation, vasopressor support, and organ support. The key goals are starting appropriate antibiotics quickly, resuscitating from shock, identifying and treating the infection source, and maintaining organ function.
Sepsis
Sepsis is a life-threatening condition caused by the body's response to an infection. It can progress to septic shock, which has a high mortality rate. The initial management of sepsis involves rapid fluid resuscitation, administration of broad-spectrum antibiotics within 1 hour, and measuring serum lactate levels and obtaining blood cultures. Implementation of a code sepsis protocol can improve compliance with treatment guidelines and reduce mortality rates by facilitating early goal-directed therapy. De-escalation of antimicrobial therapy based on the patient's clinical response is important to prevent overuse of antibiotics.
New definition of sepsis... sepsis 3
The document discusses proposed changes to the definitions of sepsis, septic shock, and related terms based on recent evidence and consensus guidelines. It summarizes the new definitions as follows:
1) Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection, assessed using a SOFA score ≥ 2 points.
2) Septic shock involves profound circulatory and cellular abnormalities indicated by persisting hypotension requiring vasopressors and serum lactate >2mmol/L, despite adequate fluid resuscitation.
3) Terms like "severe sepsis" are removed, and quick SOFA (qSOFA) criteria are suggested for evaluating sepsis outside the ICU.
Septicemia international management guideline
This document provides guidelines for the management of sepsis and septic shock. It defines key terms like sepsis, severe sepsis, septic shock, and systemic inflammatory response syndrome. It outlines variables for diagnosis and assessing organ dysfunction. It recommends initial resuscitation goals within 3-6 hours including measuring lactate, administering antibiotics and fluids, and applying vasopressors if needed. It provides guidelines for diagnosis, source control, antibiotic therapy, fluid therapy, vasopressor use, and other supportive treatments. Recommendations are evidence-based with assigned grade levels.
Sepsis
Sepsis and septic shock are life-threatening conditions caused by the body's response to infection. Sepsis occurs when infection leads to organ dysfunction, while septic shock involves profound circulatory and cellular abnormalities that greatly increase the risk of death. Risk factors include older age, pregnancy, chronic diseases, and weak immune systems. Common causes are infections of the lungs, digestive tract, urinary system, and bloodstream. Signs and symptoms include inflammation, low blood pressure, organ dysfunction, tissue hypoperfusion, and coagulation abnormalities. Treatment involves antibiotics, IV fluids, vasopressors, supportive care, and surgery to remove the infection source.
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This document summarizes a presentation on sepsis given by Dr. Shami Kumar. It defines sepsis according to the Sepsis-1, Sepsis-2, and Sepsis-3 definitions. The Sepsis-3 definition identifies sepsis as life-threatening organ dysfunction caused by a dysregulated host response to infection, as evidenced by an acute change in SOFA score of 2 points or more. It also defines septic shock and discusses the epidemiology, identification, management, and controversies regarding sepsis.
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Sepsis
Enumerates the latest advancements in the management of sepsis and the search into its pathophysiology.
Sepsis and septic shock
Sepsis is a life-threatening organ dysfunction caused by a dysregulated response to infection. Septic shock is a more severe form of sepsis involving significantly decreased blood pressure and elevated lactate levels despite fluid resuscitation. Key factors in the pathophysiology of sepsis and septic shock include vasodilation, decreased peripheral resistance, distributive shock, and potential coagulopathy and organ dysfunction. Early recognition and treatment through IV fluids, vasopressors, antibiotics, source control and supportive care are important for improved survival.
Septic shock management (1)
This document discusses sepsis diagnosis and management. It provides historical context on defining sepsis and outlines diagnostic criteria. Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated response to infection. Common infections that cause sepsis include those of the lung, abdomen, and urine. Management involves initial resuscitation, administering appropriate intravenous antibiotics within 1 hour, and controlling the infection source when possible through procedures like drainage or debridement. Vasopressors, fluid resuscitation, and inotropes may be needed to support blood pressure and organ perfusion.
Sepsis And Septic Shock
The document discusses concepts related to sepsis, severe sepsis, and septic shock. It provides statistics on the incidence and mortality of these conditions. It also describes the pathophysiology of sepsis, including the roles of inflammation, coagulation abnormalities, and hemodynamic changes. Potential mediators such as cytokines, nitric oxide, and endotoxin are examined in the development of septic shock.
Surviving Sepsis Guidelines Updated
The document summarizes updated guidelines from the 41th Society of Critical Care Medicine Meeting for treating sepsis. Key changes include recommending crystalloids like saline for initial fluid resuscitation; using norepinephrine as the first choice vasopressor; considering corticosteroids for refractory shock; using higher PEEP and recruitment maneuvers for ARDS; and considering procalcitonin to determine if antibiotics can be stopped. The Surviving Sepsis guidelines were previously criticized for being funded primarily by Eli Lilly without disclosure.
Severe sepsis and septic shock :evaluation and management
Sepsis and septic shock are life-threatening medical emergencies caused by dysregulated host response to infection leading to organ dysfunction. Management involves immediate evaluation and treatment, initial fluid resuscitation, early goal directed therapy including antibiotics and source control. Vasopressors, corticosteroids, glucose control, ventilation and DVT prophylaxis are also important supportive therapies to treat sepsis and prevent complications. The goal is to treat the infection and reverse the associated organ dysfunction.
Septic shock
Septic shock is a life-threatening condition that arises when sepsis leads to dangerously low blood pressure and problems in organ function. It results from an infection that causes changes throughout the body. Early recognition and treatment are important, including administering antibiotics within an hour, aggressive fluid resuscitation, and monitoring for organ dysfunction. Goals of management are restoring blood pressure, reversing signs of low perfusion, and treating the underlying infection while avoiding additional organ injury.
Sepsis 2017
The document discusses definitions, epidemiology, etiology, risk factors, and scoring systems related to sepsis. It defines sepsis as a life-threatening organ dysfunction caused by a dysregulated response to infection. Sepsis exists on a continuum of severity, ranging from infection to septic shock, which can lead to multiple organ dysfunction syndrome and death. The Sequential Organ Failure Assessment (SOFA) score and quick SOFA (qSOFA) score are used to assess organ dysfunction and predict mortality in sepsis patients.
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Sepsis In critical care 2019 final
This document discusses definitions, diagnosis, and management of sepsis. It covers:
- The history and updates of sepsis definitions from 1991 to the current Sepsis-3 criteria in 2016. Sepsis-3 aims to identify sicker patients but relies on subjective criteria.
- Guidelines for sepsis management, including initial resuscitation bundles from the Surviving Sepsis Campaign and controversies around early goal-directed therapy. Personalized approaches are now recommended.
- Ongoing research on various sepsis treatments, including fluids, vasopressors, steroids, antibiotics, and other emerging therapies, with mixed evidence on best practices. Rapid treatment remains important but a personalized approach is needed.
Sepsis and septic shock guidelines 2021. part 1
1. Sepsis is a critical imbalance between oxygen supply and demand that can affect any system. Serum lactate levels rise in response to tissue hypoxia and higher levels correlate with poorer outcomes.
2. Guidelines recommend screening high-risk patients for sepsis and using standard treatment protocols. Blood lactate should be measured in suspected cases and treatment begun immediately.
3. Fluid resuscitation of at least 30mL/kg should begin within 3 hours, guided by dynamic measures over static parameters alone. Antimicrobial therapy should also begin immediately or within 1-3 hours depending on risk level and presence of shock.
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- Sepsis is a systemic inflammatory response caused by infection that can progress to severe sepsis and septic shock. Severe sepsis is defined as sepsis with organ dysfunction, while septic shock involves hypotension refractory to fluid resuscitation along with lactate levels over 2 mmol/L despite fluid resuscitation.
- The pathophysiology involves an initial infection that triggers a systemic inflammatory response and release of cytokines and mediators, leading to endothelial damage, coagulation abnormalities, hypotension, and ultimately multiple organ dysfunction if not treated.
- Treatment involves early goal-directed therapy within 3-6 hours including antibiotics, fluid resuscitation, vasopressors, inotropes, and measures to optimize
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This document discusses shock, which is a profound hemodynamic and metabolic disturbance characterized by failure of the circulatory system to maintain adequate organ perfusion. There are four main types of shock: cardiogenic, hypovolemic, distributive, and obstructive. The document outlines the etiology, pathophysiology, clinical presentation, diagnostic evaluation, and management of each type of shock. It emphasizes the importance of early goal-directed therapy and treatment of the underlying cause of shock to increase cardiac output and tissue perfusion in order to prevent multiple organ dysfunction.
Management of shock
1. Shock is characterized by inadequate oxygen delivery to tissues due to a mismatch between supply and demand. Compensatory mechanisms include increased heart rate and vascular tone, but signs include tachycardia, pale skin, prolonged capillary refill time, and hypotension.
2. Shock is classified based on severity (compensated vs. hypotensive) and etiology (hypovolemic, distributive, cardiogenic, obstructive). Management involves rapid fluid resuscitation and treatment of the underlying cause.
3. Hemorrhagic shock results from blood loss that depletes circulating volume. Early identification, airway control, fluid resuscitation, and source control are crucial, as is following
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Sepsis resuscitation bundle
Sepsis resuscitation bundle aims to decrease mortality from severe sepsis through education and implementation of evidence-based care bundles. It defines sepsis, SIRS, and types of sepsis. The sepsis resuscitation bundle outlines goals to measure lactate, obtain blood cultures, administer antibiotics within 3 hours, deliver 20mL/kg fluids for hypotension and lactate over 4 mmol/L, consider urinary catheter, and achieve CVP of 8 mmHg and ScvO2 of 70% if hypotension persists despite fluids. The progression of sepsis without treatment can lead to further decrease in oxygenation, lower blood pressure, and death.
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- Common infectious organisms include gram-positive bacteria and opportunistic fungi/viruses in immunocompromised patients. Culture-negative sepsis occurs in around half of cases.
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- Management
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Diabetic ketoacidosis is a medical emergency caused by a lack of insulin and results in hyperglycemia, ketone production, and metabolic acidosis. It commonly occurs in people with type 1 diabetes but is increasingly seen in type 2 diabetes as well. Symptoms include thirst, frequent urination, nausea, vomiting, abdominal pain, and a fruity odor on the breath. Treatment involves intravenous fluids, insulin therapy, electrolyte replacement, and identifying and treating any underlying precipitating illnesses. Complications can include cerebral edema, hypoglycemia, and circulatory collapse if treatment is delayed.
Pediatric_Shock.pptx
This document discusses the stages and types of shock. It begins by outlining the stages of shock as compensated, uncompensated, and irreversible. It then defines the main types of shock as hypovolemic, distributive, cardiogenic, and obstructive. For each type of shock, the document provides the etiology, clinical presentation, differentiation from other types, and general management approach. It particularly focuses on hypovolemic/hemorrhagic, cardiogenic, and septic shock, outlining their specific therapies which include fluid resuscitation, vasopressors, antibiotics, and other targeted interventions.
Sepsis & septic shock an updated management
1) Sepsis and septic shock are systemic inflammatory responses to infection that can lead to organ dysfunction and death. The management involves recognizing the condition, administering antibiotics and fluids, controlling the infection source, and providing supportive organ care.
2) Diagnostic criteria include signs of infection along with dysregulated inflammatory response and organ dysfunction. Management goals within 3-6 hours include antibiotics, fluid resuscitation, lactate measurement, vasopressors for hypotension, and in some cases steroids and glucose control.
3) Common infection sites include the lungs, urinary tract, abdomen, and intravenous lines. Antibiotics should have appropriate spectrum and be given quickly based on likely pathogens. Other supportive therapies
Shock
This document discusses different types of shock including hypovolemic, septic, cardiogenic, neurogenic, and anaphylactic shock. It provides details on the definition, pathophysiology, clinical presentation, risk factors, and management of each type. For hypovolemic shock, it further discusses classification, fluid resuscitation, indicators of successful resuscitation, and choice of crystalloid versus colloid fluids. Septic shock is emphasized as an important type that can lead to multiple organ failure.
02 shock
1) Shock is defined as inadequate tissue perfusion resulting from low blood pressure and abnormal cellular metabolism. The main types of shock are hypovolemic, distributive, and cardiogenic.
2) Hypovolemic shock occurs when intravascular volume is decreased, such as from blood loss, and requires fluid resuscitation. Septic shock, a form of distributive shock, involves infection and organ dysfunction and responds to antibiotics, fluids, and vasopressors.
3) Cardiogenic shock results from heart failure or damage and may be caused by myocardial infarction. It requires hemodynamic support through medications like dopamine or norepinephrine while the underlying cardiac issue is addressed.
Shock
1) Shock is defined as inadequate tissue perfusion resulting from low blood pressure and abnormal cellular metabolism. The main types of shock are hypovolemic, distributive, and cardiogenic.
2) Hypovolemic shock occurs when intravascular volume is decreased, such as from blood loss, and requires fluid resuscitation. Septic shock, a form of distributive shock, involves infection and organ dysfunction and responds to antibiotics, fluids, and vasopressors.
3) Cardiogenic shock results from heart failure or damage and presents with low output and adequate fluid levels. It may be treated with inotropes, vasopressors, and procedures like LVAD or transplant
Obstetric shock.PDF
Obstetric shock is caused by circulatory inadequacy resulting in poor tissue perfusion and cellular hypoxia. There are four phases of general changes in shock - the first two are reversible with treatment, the third is possibly reversible, and the fourth is irreversible and involves multiple organ failure. Management of shock involves stopping bleeding, volume resuscitation, oxygen supplementation, antibiotics for infection, vasopressors, and treating underlying causes.
Sepsis 05 12 definitief
1) Sepsis is a systemic inflammatory response to infection that can lead to organ dysfunction. It ranges from sepsis to severe sepsis with organ dysfunction to septic shock with hypotension.
2) Early goal directed therapy aims to optimize oxygen delivery through fluid resuscitation, vasopressors if needed, and blood transfusion to maintain certain goals such as a central venous pressure of 8-12 mmHg and central venous oxygen saturation above 70% within 6 hours.
3) Early goal directed therapy within 6 hours that includes early antibiotics, fluid resuscitation, and maintaining blood pressure and oxygen delivery goals can significantly reduce mortality from sepsis.
Similar to Sepsis and septic shock guidelines (20)
Sepsis in surgical patients and its biomarkers.pptx
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This document provides guidelines for moderate sedation/analgesia (conscious sedation). It defines levels of sedation from minimal to general anesthesia. Moderate sedation involves patients responding purposefully to verbal commands with spontaneous breathing. The guidelines discuss patient evaluation, monitoring, personnel, equipment, drugs and discharge criteria for providing moderate sedation. Proper patient screening, credentialed practitioners and personnel, appropriate facilities and emergency equipment are emphasized to minimize risks while allowing benefits of sedation for certain medical procedures.
fatal asthma.pptx
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive function. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Updated algorithm of ER – ICU - In - patients guidelines.pptx
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Blood Bank Lecture .pptx
Blood units are transported from the central blood bank to the blood bank at BB Meegat General Hospital. Upon receipt, staff must monitor and record the temperature of transport containers to ensure blood products are within specified temperature ranges. Staff also inspect each blood unit, checking for hemolysis, leakage, damage, and verifying ABO and Rh typing. Units are then organized by blood type and labeled as ready for cross-match or reserved. Daily preservation tasks include temperature monitoring, checking expiration dates, and inventory levels. Blood is then delivered to hospital departments as needed upon receiving transfusion request forms and completing cross-match details.
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Post covid-19 syndrome, also known as long covid, refers to symptoms that can persist for weeks or months after recovery from the initial acute illness. While people are not infectious during this time, there is no agreed upon definition. A wide range of long-term symptoms have been reported, including fatigue, chest pain, muscle pain, loss of smell, and depression. Certain groups, such as older individuals, those who are obese, and people with diabetes or lung/kidney disease, appear to be at higher risk of developing long-term effects from covid-19.
Sepsis hemodynamic update part two
Dr. Mohammed Abdelaziz Salim
ICU physician
Meeqat General Hospital
sepsis SSC 2021 Updates Ventilation and additional therapy
This document discusses ventilation strategies and additional therapies for sepsis patients with respiratory failure. It covers conservative oxygen targets, types of respiratory failure, benefits of non-invasive ventilation (NIV) and positive airway pressure (PAP), and risks of NIV. The Berlin definition for acute respiratory distress syndrome (ARDS) severity is also presented. Recommendations are provided for mechanical ventilation settings and various treatments for sepsis patients.
Sepsis scoring
This document discusses sepsis scoring systems. It describes the historical definitions and consensus guidelines for sepsis from 1991 to 2016. It also discusses the Surviving Sepsis Campaign from 2004 to 2008. The document compares different scoring systems for sepsis like SIRS, SOFA, qSOFA, and MEWS and explains which are best for identifying sepsis in ICU versus non-ICU patients. It outlines the pathogens commonly associated with sepsis and trends in incidence and mortality.
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Medication error, nursing responsibility
This document defines medication error and outlines procedures for reporting medication errors. It also lists common types of medication errors including prescribing errors, omission errors, wrong time errors, and improper dose errors. Causes of errors include look-alike and sound-alike drug names, illegible handwriting, and unapproved abbreviations. Nursing responsibilities in preventing errors and standard precautions are discussed.
Continuous renal replacement therapy crrt
CRRT is a continuous renal replacement therapy that provides a gentler form of dialysis for critically ill patients. It works through slow, continuous removal of waste and fluid over multiple days rather than the typical 4 hour sessions of hemodialysis. This puts less stress on the heart. CRRT can be delivered through various modes including continuous venovenous hemofiltration, hemodialysis, or hemodiafiltration that utilize diffusion, convection, or both to clean the blood. Anticoagulation is required to prevent clotting of the dialysis circuit and can include regional citrate or low-dose heparin.
Deep venous thrombosis dvt
Deep vein thrombosis (DVT) is a blood clot that forms in the deep veins, usually in the legs. Virchow's triad of venous stasis, hypercoagulability, and endothelial injury can lead to thrombus formation. Risk factors include age, immobilization, surgery, cancer, and genetic factors. Patients may experience pain, swelling, warmth, and tenderness. Diagnosis involves a Wells score, D-dimer test, ultrasound or venography. Treatment is anticoagulation with heparin, low molecular weight heparin, fondaparinux, or warfarin to prevent pulmonary embolism. Long-term anticoagulation and compression stockings can help prevent
Bed sore management
This document discusses bed sore management and prevention. It defines bed sores as injuries to the skin and underlying tissues caused by prolonged unreleived pressure. Risk factors include advanced age, malnutrition, physical disability, and chronic illness. Bed sores are staged from Stage 1 involving changes in skin color to Stage 4 involving full thickness tissue loss reaching muscle, bone and tendon. Treatment involves surgical procedures like debridement, dressings, antibiotics, regular posture changes, diet, and hygiene to prevent further complications. The nursing perspective focuses on assessing risk factors, inspecting the skin and environment, staging any sores present, and ensuring regular care and prevention measures.
Chest intubation indications,precautions and management
Chest tube insertion or thoracostomy is a life-saving procedure where a plastic tube is inserted into the pleural cavity to drain fluid, air, or both. It can be performed at the bedside, and every surgical/ER resident is expected to be trained and able to perform it. The document provides details on indications for the procedure, equipment needed, patient positioning, steps for insertion, post-procedure care and monitoring, potential complications, and criteria for tube removal.
Portable ventilator
MR. MOHAMMAD TALAL AL JOHANY
RESPIRATORY THERAPIST
Meqaat Hospital Madina
POST TEST
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Covid19 corona management -كوفيد19
OVID-19 Management experience
What we learned from bedside experience in COVID-19 treatment
Dr. Essam A. Salem, ICU Registrar, Meeqat GENERAL.HOSPITAL, Head OF ICU Unit Meeqat General Hospital
Sedation
Hassan Mohamed Ali
Associate professor of anesthesia and pain management, Anesthesia department, Cairo University.
MB.B.ch, M Sc, M.D, FCAI, DESA
Meeqat General Hospital, Madinah Munawarah
Conscious sedation course
This document provides guidelines for moderate sedation/analgesia (conscious sedation). It defines the different levels of sedation from minimal to general anesthesia. Moderate sedation is described as a drug-induced depression where patients can respond to commands. It outlines safety procedures for patient evaluation, monitoring during procedures, qualifications of medical personnel, facilities requirements, and discharge criteria. The goal is to allow clinicians to provide sedation benefits to patients safely by minimizing risks.
Medical permission for patient
lecture By Mr Rayed Alarwi
Meeqat General Hospital Complex ,Madina , KSA
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Sepsis and septic shock guidelines
- 8. Sepsis : Is a clinical syndrome of life- threatening organ dysfunction caused by a dysregulated response to infection
- 10. :Septic shocks Is a subset of sepsis with significantly increased mortality due to severe abnormalities of circulation andor cellular metabolism Involves persistent hypotension (defined as the need for vasopressors to maintain mean arterial pressure≤ 65 mm Hg , and a serum lactate level 2 mmol/L despite adequate volume resuscitation <
- 13. Etiology : Predisposing factors include: . Diabetes mellitus . Cirrhosis . Leukopenia . Leukopenia . Invasive
- 15. Pathophysiology : Initially , arteries and arterioles dilate , decreasing peripheral arterial resistance ; cardiac output typically increases . This stage has been referred to as warm shock Even in the stage of increased cardiac output ,vasoactive mediators cause blood flow to bypass capillary exchange vessels ( a distributive defect ) Coagulopathy may develop because of intravascular coagulation with consumption of major clotting factors , excessive fibrinolysis in reaction thereto , and more often a combination of both .
- 18. Signs and symptoms : Sepsis: . Temp : >38.3 C . Heart rate > 90 beats/minute .respiratory rate : > 20 breath/minute . Diaphoresis . WBC > 15000 UL , <4000 , or 10% bands Septic shock: Sepsis sign+ . Confusion . Decrease aletrness . Dyspnea . Warm skin cool and pale extremeties ( later sign ) . Peripheral cyanosis and mottling. . oliguria
- 22. . Perfusion restored with IV fluids and sometimes vasopressors . O2 support . Broad-spectrum antibiotics . Source control . Supportive measures ( eg, corticosteroids , insulin)
- 23. Patients with septic shock should be treated in an ICU . The following should be monitored hourly : . CVP , PAOP , or ScvO2 . pulse oximetry . ABGs . Blood glucose , lactate , and electrolyte levels . Urine output , a good indicator of renal perfusion
- 25. Perfusion restoration : . Target ScvO2 is 70% . Target CVP reaches 8 mmHg -12 mmHg ( 10 cm H2O ) for non ventilated patient . . Norepinephrine or vasopressin – to maintain MAP 60 mmHg . Correction of albumine level ≤ ≤
- 28. Other supportive measures : . Normalization of glucose – IV infusion (1-4 units/hr) to maintain glucose between 110 – 180 mg/dl . See glucose control protocol in ICU . Corticoisteroid therapy – hydrocortisone 50 mg IV q 6 h (or 100 mg q 8 h) . DVT prophylaxis . PUD prophylaxis . Sedation in ICU . Delirium management
- 30. Key points : . Sepsis and septic shocks are increasingly severe clinical syndromes of life-threatening organ dysfunction caused by a dysregulated response to infection . An important component is critical reduction in tissue perfusion , which can lead to acute failure of multiple organs , including the lungs , kidneys , and liver
- 31. . Early recognition and treatment is the key to improved survival . Resuscitate with IV fluids and sometimes vasopressors titrated to optimize central venous oxygen saturation ( ScvO2) and preload , and lower serum lactate levels
- 32. . Control the source of infection by removing catheters , tubes , and infected and/or necrotic tissue and by draining abscesses . Give empiric broad-spectrum antibiotics directed at most likely organisms and switch quickly to more specific drugs based on culture and sensitivity results Correction of serum albumine