This document provides an overview of suspended animation and cryonics. It discusses the history and concepts of suspended animation, how cryonics works by slowing life processes at low temperatures without death, and recent developments using hydrogen sulfide to induce reversible hibernation. The document outlines the process of cryopreservation where patients are declared legally dead, their bodies are preserved and cooled, and then stored in liquid nitrogen tanks with the hope that future medical advances may be able to revive them. It explores related terms, obstacles, and the future potential scope of suspended animation and cryonics.

1. Mahesh Patil
M130379me

2.  What is suspended animation?
It is the slowing of life processes by external
means without termination.

3. Scope of presentation
 Introduction
 History
 Suspended animation Cryonics
 Related terms and concepts
 How it is done?
 Recent developments
 Obstacles
 future scope

5.  Suspended : Caused to stop for a while
 Animation : to give movement ; to give life
De-animate
Suspend
Re-animate

6. Some interesting terms
 Cryonics
 Cryopreservation ( Cryoconservation )
 Cryoprotectants (anti-freeze agent)
 Definition of death legally dead!
 Hibernation
 Vitrification Glass transition temperature
 Induced hypothermia
 Role of H2S and comparison with H2O

7. Cryonics
 Low temperature preservation
 hope of future healing and cure
 First proposed in 1962
 270 people have gone under cryopreservation
 Stopping of enzymatic or chemical activity
 Coating the material to be frozen with cryoprotectants

8.  Information-theoretic death Vs clinical death
destruction of the information within a human brain
to such an extent that recovery of the original person
is theoretically impossible by any physical means
 Hypothermia: metabolic rate maintainace.

9. Vitrification
 Amorphous substances
 Transformation of substance into glass
 Glass transition temperature
 Removal of water
 Sharp edge action

10. Need of vitrification
 Removal of water
 Injecting cryoprotectants ( gycerol based)
 Sharp edge action
 Volume expansion of during solidification

11. How it is done?!!
 Join any cryonics facility Be a member
 When your heart stops pronounced legally dead!
 Emergency response team
 Body in packed with ice
 Injection of heparin (anticoagulant): to prevent
clotting
 Transport Vitrification (Cryoprotectant)
 Cooled using dry ice ( till -130 Celsius )
 Immersion in liquid Nitrogen ( -196 Celsius )

12.  Preservation
tank

13. Recent developments
 Role of H2S
binds to cytochrome oxidase ( mitochondria )
stops oxygen to bind
slowdown of metabolism
hibernation
 How hibernation is related?
 Example of power and lamp

14.  Experiment in 2005 on mice:
 low dosage of H2S ( 81 ppm )
 breathing rate : 120 beats/min 10 beats/min
body temperature: 37 °C to 2 °C above ambient
cold blooded (poikilotherm)

15.  Future scope
 Benefits: medical, space and many more

16. Referances
 Contributions of Mark Roth ( University of
Washington )
 Alcor Life Extension Foundation: Cryonics
 Advances in human cryopreservation, 2007, Florida
 Internet