This presentation taking about what is called QUANTUM DOTs and its application as pH Probes for Study of the Enzyme Kinetics.
Ala' Naimat - Universidad de Santiago de Compostela - Spain
This includes what is Quantum Dots and their properties ,types of synthesis methods of nano materials such as top down, bottom up etc.It includes few things about Carbon Quantum Dots.
Quantum dots are semiconductor nanoparticles that confine electrons and holes in all three dimensions. They are made using different methods like lithography, colloidal synthesis, or epitaxy. Quantum dots have discrete energy levels that depend on their size and shape. They have potential applications in solar cells, LEDs, bioimaging, drug delivery, and anti-counterfeiting due to their tunable light emission properties.
This presentation discusses quantum dots, which are nanoparticles that exhibit quantum confinement. Quantum dots are usually made of semiconductors and their optical and electrical properties depend on their size due to quantum confinement effects. They can be made through lithography, colloidal synthesis, or epitaxial growth methods. The presenter notes that quantum dots made of heavy metals like cadmium may not be commercially viable due to legislation, so silicon quantum dots are being researched as a non-toxic alternative. Potential applications of quantum dots include solar cells, biosensing, LEDs, displays, and lasers due to their size-dependent properties.
Quantum dots are semiconductor nanocrystals that exhibit size-dependent optical and electrical properties due to quantum confinement effects. Their bandgap increases as size decreases, causing emitted light to shift to higher energies (blueshift). They are fabricated using lithography, colloidal synthesis, or epitaxy. Potential applications include use in QLED displays for televisions and phones (offering higher brightness and efficiency than OLEDs), solar cells, medical imaging to detect diseases, and programmable matter that can change properties in response to electron manipulation.
Quantum dots can be made through lithography, colloidal synthesis, or epitaxy. Lithography uses a polymer mask and electron beam to pattern metal layers on quantum wells. Colloidal synthesis immerses semiconductor microcrystals in glass to form nearly equal sized microcrystals. Epitaxy involves growing smaller bandgap semiconductors on larger bandgap compounds, restricting growth with a mask to form quantum dots. Potential applications of quantum dots include computing, LEDs, photovoltaics, medical imaging, cell imaging, cancer detection and targeted drug delivery.
Quantum dots are nanocrystalline semiconductor particles between 1-10 nm in size that display quantized energy levels. Their spectral properties depend on their size - smaller quantum dots emit higher energy light while larger ones emit lower energy. This allows using quantum dots of different sizes to produce a range of colors. Potential applications of quantum dots include use in TV and display technologies due to their pure colors and long lifetimes. Quantum dots are also being explored for biological and chemical applications such as cancer treatment where they can target organs more precisely than conventional drugs.
This includes what is Quantum Dots and their properties ,types of synthesis methods of nano materials such as top down, bottom up etc.It includes few things about Carbon Quantum Dots.
Quantum dots are semiconductor nanoparticles that confine electrons and holes in all three dimensions. They are made using different methods like lithography, colloidal synthesis, or epitaxy. Quantum dots have discrete energy levels that depend on their size and shape. They have potential applications in solar cells, LEDs, bioimaging, drug delivery, and anti-counterfeiting due to their tunable light emission properties.
This presentation discusses quantum dots, which are nanoparticles that exhibit quantum confinement. Quantum dots are usually made of semiconductors and their optical and electrical properties depend on their size due to quantum confinement effects. They can be made through lithography, colloidal synthesis, or epitaxial growth methods. The presenter notes that quantum dots made of heavy metals like cadmium may not be commercially viable due to legislation, so silicon quantum dots are being researched as a non-toxic alternative. Potential applications of quantum dots include solar cells, biosensing, LEDs, displays, and lasers due to their size-dependent properties.
Quantum dots are semiconductor nanocrystals that exhibit size-dependent optical and electrical properties due to quantum confinement effects. Their bandgap increases as size decreases, causing emitted light to shift to higher energies (blueshift). They are fabricated using lithography, colloidal synthesis, or epitaxy. Potential applications include use in QLED displays for televisions and phones (offering higher brightness and efficiency than OLEDs), solar cells, medical imaging to detect diseases, and programmable matter that can change properties in response to electron manipulation.
Quantum dots can be made through lithography, colloidal synthesis, or epitaxy. Lithography uses a polymer mask and electron beam to pattern metal layers on quantum wells. Colloidal synthesis immerses semiconductor microcrystals in glass to form nearly equal sized microcrystals. Epitaxy involves growing smaller bandgap semiconductors on larger bandgap compounds, restricting growth with a mask to form quantum dots. Potential applications of quantum dots include computing, LEDs, photovoltaics, medical imaging, cell imaging, cancer detection and targeted drug delivery.
Quantum dots are nanocrystalline semiconductor particles between 1-10 nm in size that display quantized energy levels. Their spectral properties depend on their size - smaller quantum dots emit higher energy light while larger ones emit lower energy. This allows using quantum dots of different sizes to produce a range of colors. Potential applications of quantum dots include use in TV and display technologies due to their pure colors and long lifetimes. Quantum dots are also being explored for biological and chemical applications such as cancer treatment where they can target organs more precisely than conventional drugs.
Quantum dots are nanocrystals made of semiconductor materials that are small enough to exhibit quantum mechanical properties. They have potential applications in biology, computing, solar cells, and more. Specifically, carbon quantum dots are a new class of fluorescent carbon nanomaterials that have attractive properties such as high stability, good conductivity, low toxicity, and environmental friendliness. They show potential for uses such as biological tagging, labeling, imaging, and photocatalysis. Research is ongoing to further develop quantum dot applications in areas like solid-state quantum computing, solar cells, and biomedical uses.
This document discusses nanobiotechnology and the functionalization of enzymes. It describes various types of nanomaterials like carbon nanotubes, quantum dots, and dendrimers that can be used as matrices for enzyme immobilization. Methods of immobilizing enzymes on nanomaterials include electrostatic adsorption, covalent attachment, conjugation using protein affinity, and direct conjugation. Immobilizing enzymes provides benefits like increased stability but can introduce mass transfer limitations. Overall, nanomaterials provide a high surface area support for immobilizing enzymes with various applications.
This presentation is a simple explain of Bionanoimaging which introduce this area completely. You can use this PPTx File to present in your class and seminars as well. I prepare this file to present in Tabriz University of Medical Sciences when I was a MSc Medical Nanotechnology student. It will be useful for you too.
This document provides an introduction to quantum dots. It discusses that quantum dots are nanocrystals that behave like single atoms due to their small size on the nanometer scale. Their optical properties, such as emission wavelength, can be tuned by varying their size. Common quantum dot materials include CdS, CdSe, and PbS. The document also explains that quantum confinement results in an increased bandgap as particle size decreases due to spatial confinement of electron-hole pairs. Finally, it briefly outlines some applications of quantum dots such as in solar cells, LEDs, displays, and biological imaging.
E = g lk+ 2
+ − − +
r m 0 m 0 4 ε 0 h ( ε 0 2 e 0 m 0
8 em hm πεr 2 2ε ) m m hm
Brus, L. E. J. Phys. Chem. 1986, 90, 2555
Semiconductor quantum dots are nanocrystals made of semiconductor materials such as CdSe, ZnSe, ZnS, and ZnO. They exhibit size-dependent optical and electronic properties due to
Quantum dots are nanometer-scale semiconductor crystals composed of groups II-VI or III-V elements. They are defined as particles smaller than the exciton Bohr radius, where excitons are confined in all three dimensions. Quantum dots were discovered in the 1980s during research in glass matrices and colloidal solutions. The size, energy levels, and emission color of quantum dots can be precisely controlled, and the absorption and emission wavelengths depend on dot size. Larger dots have longer wavelengths and lower frequencies than smaller dots.
Quantum dots are semiconductor nanoparticles that exhibit quantum confinement effects due to their small size. They can be made through various methods like colloidal synthesis or electron beam lithography. Their optical properties depend on size, with smaller quantum dots emitting higher energy light. Potential applications include uses in computing, biology, photovoltaics, and light emitting devices.
The document discusses nanotechnology and its applications. It begins with definitions of nanotechnology as the study and use of structures between 1 and 100 nanometers in size. It then describes several methods for characterizing and synthesizing nanocrystals, including physical methods like inert gas condensation and chemical methods like metal nanocrystal synthesis via reduction. Finally, it outlines some applications of nanotechnology such as in medicine, biotechnology, energy, and industry.
This document discusses various approaches for synthesizing nanomaterials, dividing them into top-down and bottom-up categories. Top-down approaches begin with bulk materials and make them smaller, such as through mechanical milling, lithography, sputtering, laser ablation, and electrospinning. Bottom-up approaches build up nanomaterials from molecular components. Common top-down techniques include mechanical milling of materials down to the nanoscale, electrospinning to produce nanofibers, and lithography which uses focused beams of light or electrons to construct nanostructures.
The document discusses various applications of nanotechnology across different fields such as medicine, electronics, environment, fashion, agriculture, food, construction, and daily life. Some key applications mentioned include using nanoparticles for targeted drug delivery in cancer treatment, developing flexible electronics, water purification, antibacterial textiles, increasing crop yields, food preservation, and construction materials. The conclusion states that nanotechnology is a rapidly growing field that could have both benefits and risks but will likely play an important role in the future if developed sustainably.
This document discusses quantum dots, which are semiconductors on the nanometer scale that obey the principle of quantum confinement. The energy band gap of quantum dots determines the wavelength of light they can absorb and emit, and this wavelength depends on the size of the dot. Solutions containing quantum dots of different sizes appear different colors because the particles absorb and emit light within the visible spectrum. Potential applications of quantum dots include improving solar cells, use in televisions, and medical imaging.
- Quantum dots are semiconductor nanoparticles that exhibit unique optical and electronic properties due to their small size (around 4 million dots fit in a 2cm area).
- Current research is investigating applications for quantum dots in areas like displays, solar cells, computer storage, and programmable matter. Quantum dot displays could produce richer colors than LCDs and be integrated into flexible or multi-purpose screens. Quantum dot solar cells may lead to higher efficiency photovoltaics.
- The future potential applications of quantum dots include foldable or color-changing screens, invisible solar coatings, vastly increased computer storage capacity, and materials with customizable properties through electron manipulation at the quantum level.
This presentation contains a basic introduction to quantum dots,their discovery, properties, applications,advantages,limitations and future prospects.It also contains a brief overview of experimental work carried out and results obtained during my summer term project.
Nanoparticles for magnetic resonance imagingAlex Chris
This document discusses the use of various types of nanoparticles for molecular imaging applications such as magnetic resonance imaging (MRI) and computer tomography (CT). It describes how gold nanoparticles, quantum dots, iron oxide nanoparticles, carbon nanotubes, dendrimers, and other nanoparticles are being investigated and developed as contrast agents for molecular imaging due to their tunable properties and potential for functionalization and targeted delivery. For example, one study demonstrated how antibody-conjugated gold nanorods could selectively target and image squamous cell carcinoma tumors using CT. Overall, the controlled properties of engineered nanoparticles show promise for improving molecular imaging techniques.
It has been almost decades since the “war on cancer” was declared. It is now generally
believed that personalized medicine is the future for cancer patient management.
Possessing unprecedented potential for early detection, accurate diagnosis, and
personalized treatment of cancer, nanoparticles have been extensively studied over the last
decade. In this report, I will try to summarize the current state-of-the-art nanoparticles in
biomedical applications targeting cancer. Multi- functionality nanoparticle-based agents.
Targeting ligands, imaging labels, therapeutic Drugs, and other. And the Role of Chemical
Engineers in this field and the promise that it holds for future.
Carbon nanotubes are allotropes of carbon that exist as cylindrical structures with a high length-to-diameter ratio. They can be single-walled or multi-walled depending on the number of concentric cylinders. Carbon nanotubes have extraordinary properties including high strength, stiffness, thermal conductivity, and electrical conductivity. Due to these properties, carbon nanotubes show promise for applications in electronics, hydrogen storage, solar cells, biosensors, drug delivery, and more.
This document summarizes an outline for a presentation on optical imaging probes by Dr. Chalermchai Pilapong. It discusses various types of probes including organic molecules, metal complexes, and inorganic nanocrystals. For organic molecules, it focuses on small fluorescent dyes and strategies to improve their properties. Metal complexes discussed make use of phosphorescence rather than fluorescence. Inorganic probes highlighted are quantum dots and metal nanoclusters, which offer size-tunable optical properties and potential for multi-functionalization. The document provides examples of targeting and biomedical applications for each type of probe.
The interaction of QDs with RAW264.7 cells_ nanoparticle quantification, upta...Olga Gladkovskaya
This document summarizes a study that investigated the interaction of quantum dots (QDs) with RAW264.7 macrophage cells. Specifically, it quantified QD uptake kinetics over time using flow cytometry, studied the effect on cell function and viability, and examined immune responses. Small, green-emitting CdTe QDs with diameters of 2.1 nm were incubated with RAW264.7 cells. Uptake kinetics were quantified and optimal parameters like concentration and exposure time were identified. Cell viability, intracellular fluorescence, and inflammatory marker expression were analyzed at 12 and 24 hours. The QDs were quickly ingested and accumulated in cells, making them suitable for short-term assays, though longer term effects require further study.
Quantum dots are nanocrystals made of semiconductor materials that are small enough to exhibit quantum mechanical properties. They have potential applications in biology, computing, solar cells, and more. Specifically, carbon quantum dots are a new class of fluorescent carbon nanomaterials that have attractive properties such as high stability, good conductivity, low toxicity, and environmental friendliness. They show potential for uses such as biological tagging, labeling, imaging, and photocatalysis. Research is ongoing to further develop quantum dot applications in areas like solid-state quantum computing, solar cells, and biomedical uses.
This document discusses nanobiotechnology and the functionalization of enzymes. It describes various types of nanomaterials like carbon nanotubes, quantum dots, and dendrimers that can be used as matrices for enzyme immobilization. Methods of immobilizing enzymes on nanomaterials include electrostatic adsorption, covalent attachment, conjugation using protein affinity, and direct conjugation. Immobilizing enzymes provides benefits like increased stability but can introduce mass transfer limitations. Overall, nanomaterials provide a high surface area support for immobilizing enzymes with various applications.
This presentation is a simple explain of Bionanoimaging which introduce this area completely. You can use this PPTx File to present in your class and seminars as well. I prepare this file to present in Tabriz University of Medical Sciences when I was a MSc Medical Nanotechnology student. It will be useful for you too.
This document provides an introduction to quantum dots. It discusses that quantum dots are nanocrystals that behave like single atoms due to their small size on the nanometer scale. Their optical properties, such as emission wavelength, can be tuned by varying their size. Common quantum dot materials include CdS, CdSe, and PbS. The document also explains that quantum confinement results in an increased bandgap as particle size decreases due to spatial confinement of electron-hole pairs. Finally, it briefly outlines some applications of quantum dots such as in solar cells, LEDs, displays, and biological imaging.
E = g lk+ 2
+ − − +
r m 0 m 0 4 ε 0 h ( ε 0 2 e 0 m 0
8 em hm πεr 2 2ε ) m m hm
Brus, L. E. J. Phys. Chem. 1986, 90, 2555
Semiconductor quantum dots are nanocrystals made of semiconductor materials such as CdSe, ZnSe, ZnS, and ZnO. They exhibit size-dependent optical and electronic properties due to
Quantum dots are nanometer-scale semiconductor crystals composed of groups II-VI or III-V elements. They are defined as particles smaller than the exciton Bohr radius, where excitons are confined in all three dimensions. Quantum dots were discovered in the 1980s during research in glass matrices and colloidal solutions. The size, energy levels, and emission color of quantum dots can be precisely controlled, and the absorption and emission wavelengths depend on dot size. Larger dots have longer wavelengths and lower frequencies than smaller dots.
Quantum dots are semiconductor nanoparticles that exhibit quantum confinement effects due to their small size. They can be made through various methods like colloidal synthesis or electron beam lithography. Their optical properties depend on size, with smaller quantum dots emitting higher energy light. Potential applications include uses in computing, biology, photovoltaics, and light emitting devices.
The document discusses nanotechnology and its applications. It begins with definitions of nanotechnology as the study and use of structures between 1 and 100 nanometers in size. It then describes several methods for characterizing and synthesizing nanocrystals, including physical methods like inert gas condensation and chemical methods like metal nanocrystal synthesis via reduction. Finally, it outlines some applications of nanotechnology such as in medicine, biotechnology, energy, and industry.
This document discusses various approaches for synthesizing nanomaterials, dividing them into top-down and bottom-up categories. Top-down approaches begin with bulk materials and make them smaller, such as through mechanical milling, lithography, sputtering, laser ablation, and electrospinning. Bottom-up approaches build up nanomaterials from molecular components. Common top-down techniques include mechanical milling of materials down to the nanoscale, electrospinning to produce nanofibers, and lithography which uses focused beams of light or electrons to construct nanostructures.
The document discusses various applications of nanotechnology across different fields such as medicine, electronics, environment, fashion, agriculture, food, construction, and daily life. Some key applications mentioned include using nanoparticles for targeted drug delivery in cancer treatment, developing flexible electronics, water purification, antibacterial textiles, increasing crop yields, food preservation, and construction materials. The conclusion states that nanotechnology is a rapidly growing field that could have both benefits and risks but will likely play an important role in the future if developed sustainably.
This document discusses quantum dots, which are semiconductors on the nanometer scale that obey the principle of quantum confinement. The energy band gap of quantum dots determines the wavelength of light they can absorb and emit, and this wavelength depends on the size of the dot. Solutions containing quantum dots of different sizes appear different colors because the particles absorb and emit light within the visible spectrum. Potential applications of quantum dots include improving solar cells, use in televisions, and medical imaging.
- Quantum dots are semiconductor nanoparticles that exhibit unique optical and electronic properties due to their small size (around 4 million dots fit in a 2cm area).
- Current research is investigating applications for quantum dots in areas like displays, solar cells, computer storage, and programmable matter. Quantum dot displays could produce richer colors than LCDs and be integrated into flexible or multi-purpose screens. Quantum dot solar cells may lead to higher efficiency photovoltaics.
- The future potential applications of quantum dots include foldable or color-changing screens, invisible solar coatings, vastly increased computer storage capacity, and materials with customizable properties through electron manipulation at the quantum level.
This presentation contains a basic introduction to quantum dots,their discovery, properties, applications,advantages,limitations and future prospects.It also contains a brief overview of experimental work carried out and results obtained during my summer term project.
Nanoparticles for magnetic resonance imagingAlex Chris
This document discusses the use of various types of nanoparticles for molecular imaging applications such as magnetic resonance imaging (MRI) and computer tomography (CT). It describes how gold nanoparticles, quantum dots, iron oxide nanoparticles, carbon nanotubes, dendrimers, and other nanoparticles are being investigated and developed as contrast agents for molecular imaging due to their tunable properties and potential for functionalization and targeted delivery. For example, one study demonstrated how antibody-conjugated gold nanorods could selectively target and image squamous cell carcinoma tumors using CT. Overall, the controlled properties of engineered nanoparticles show promise for improving molecular imaging techniques.
It has been almost decades since the “war on cancer” was declared. It is now generally
believed that personalized medicine is the future for cancer patient management.
Possessing unprecedented potential for early detection, accurate diagnosis, and
personalized treatment of cancer, nanoparticles have been extensively studied over the last
decade. In this report, I will try to summarize the current state-of-the-art nanoparticles in
biomedical applications targeting cancer. Multi- functionality nanoparticle-based agents.
Targeting ligands, imaging labels, therapeutic Drugs, and other. And the Role of Chemical
Engineers in this field and the promise that it holds for future.
Carbon nanotubes are allotropes of carbon that exist as cylindrical structures with a high length-to-diameter ratio. They can be single-walled or multi-walled depending on the number of concentric cylinders. Carbon nanotubes have extraordinary properties including high strength, stiffness, thermal conductivity, and electrical conductivity. Due to these properties, carbon nanotubes show promise for applications in electronics, hydrogen storage, solar cells, biosensors, drug delivery, and more.
This document summarizes an outline for a presentation on optical imaging probes by Dr. Chalermchai Pilapong. It discusses various types of probes including organic molecules, metal complexes, and inorganic nanocrystals. For organic molecules, it focuses on small fluorescent dyes and strategies to improve their properties. Metal complexes discussed make use of phosphorescence rather than fluorescence. Inorganic probes highlighted are quantum dots and metal nanoclusters, which offer size-tunable optical properties and potential for multi-functionalization. The document provides examples of targeting and biomedical applications for each type of probe.
The interaction of QDs with RAW264.7 cells_ nanoparticle quantification, upta...Olga Gladkovskaya
This document summarizes a study that investigated the interaction of quantum dots (QDs) with RAW264.7 macrophage cells. Specifically, it quantified QD uptake kinetics over time using flow cytometry, studied the effect on cell function and viability, and examined immune responses. Small, green-emitting CdTe QDs with diameters of 2.1 nm were incubated with RAW264.7 cells. Uptake kinetics were quantified and optimal parameters like concentration and exposure time were identified. Cell viability, intracellular fluorescence, and inflammatory marker expression were analyzed at 12 and 24 hours. The QDs were quickly ingested and accumulated in cells, making them suitable for short-term assays, though longer term effects require further study.
This document describes the design and testing of a fiber optic probe to measure metabolic properties of human carotid plaque. The probe was designed to interrogate a small tissue volume (<1 mm3) and determine pH and lactate concentration in vitro. Monte Carlo simulations were used to optimize probe geometry for depth penetration. Several probe designs were tested and a final probe with a 50 micron source-receiver separation was chosen. Human carotid plaques were studied in vitro to validate experimental stability over 4 hours. The probe and experimental methods achieved the stability criteria of less than 0.03 pH change and 0.4°C temperature change per hour, demonstrating feasibility for optical spectroscopy of plaque metabolism.
This document describes the design and testing of a fiber optic probe to measure metabolic properties of human carotid plaque. The probe was designed to interrogate a small tissue volume (<1 mm3) and determine pH and lactate concentration in vitro. Monte Carlo simulations were used to model light propagation in tissue and optimize probe geometry. Several probe designs were tested and a final probe with a 50 micron source-receiver separation was chosen. Human carotid plaques were studied in vitro to validate experimental stability over 4 hours. The probe and experimental methods achieved the stability criteria of less than 0.03 pH change and 0.4°C temperature change per hour, demonstrating feasibility for optical determination of metabolic status in vulnerable plaque.
151 performance of a localized fiber opticSHAPE Society
This document describes the design and testing of a fiber optic probe to measure metabolic markers in human carotid plaque tissue samples in vitro. The probe was designed to interrogate a small volume of tissue (~1 mm3) and measure tissue lactate concentration and pH. Human plaque samples were collected and studied in a controlled in vitro setup to validate experimental stability over time. Optical absorption spectra were collected from plaque samples and related to reference measurements of lactate concentration and pH through multivariate calibration models, achieving accurate predictions. The fiber optic probe design and in vitro experimental methods were able to precisely measure metabolic markers for characterization of plaque vulnerability.
— CdTe quantum dots (QDs)/Poly (diallyldimethylammonium chloride) (PDDA) multilayer films (QDMF) have been self-assembled by layer-by-layer (LBL) technique. CdTe quantum dots (QDs) were synthesized by using Te, NaBH 4 , and CdCl 2 as precursors and mercaptopropionic acid (MPA) as stabilizer. The as-prepared composites were characterized by transmission electron microscope (TEM), Fourier transform infrared spectroscopy (FTIR), UV-vis adsorption spectrum(UV-vis), and Fluorescence spectrum(FS), respectively. It was shown that the self-assembled QDMF in this study could be used as gaseous sensors for detecting organic gases, such as ammonia, acetone, methanol and formaldehyde. The quenching mechanism of CdTe QDs multilayer films by formaldehyde was studied in detail and The detection limit was 10-236ppm.
Analytical Method Development and Validation of Prednisolone Sodium Phosphate...iosrjce
IOSR Journal of Pharmacy and Biological Sciences(IOSR-JPBS) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of Pharmacy and Biological Science. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Pharmacy and Biological Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
An introduction to the use of ICP-MS in the clinical setting, that goes on to describe some potential new application areas for advanced instrumentation such as HPLC-ICP-MS, laser ablation-ICP-MS and immuno-tagging-ICP-MS for the measurement of biomolecules.
FIBER OPTIC AIDED SPECTROPHOTOMETRIC DETERMINATION OF GADOLINIUM IN FBR REPRO...ijac123
This document describes the development of a new spectrophotometric method for determining gadolinium concentration using Alizarin Red S as the complexing agent. Key findings include:
1) Gadolinium forms a stable complex with Alizarin Red S at pH 4.6-4.8 that has maximum absorbance at 530 nm.
2) Beer's law is followed in the concentration range of 1-14 μg/mL of gadolinium.
3) The method allows for detection of gadolinium down to 0.264 μg/mL with good precision.
4) The method is proposed for determining gadolinium concentration during solvent extraction studies of gadolinium removal from nuclear
The document discusses various applications of nanotechnology in microbiology. It begins by defining nanotechnology as the manipulation of matter at the nanoscale of 1 to 100 nm. Some key applications discussed include using quantum dots for pathogen detection through fluorescence, using gold and silver nanoparticles in assays like sol particle immunoassays, and using magnetic nanoparticles in detection methods like magnetic relaxation switches that can detect as few as 5 viral particles. The document also discusses nanoparticle-based methods that enable faster, more sensitive detection of pathogens without sample preparation.
The study examines the toxicity and effects on gene expression of cadmium-based quantum dots in buffalo rat liver cells. Cadmium telluride quantum dots were synthesized using a one-pot method and their toxicity was analyzed using cell viability, cytotoxicity, and gene expression assays. The quantum dots showed significant toxicity to the cells. While concentrations were unknown due to issues determining true solution concentrations, cell viability decreased with increasing quantum dot exposure. RNA extractions were successful and yielded high quality RNA for future gene expression analysis. Further work will optimize the quantum dot synthesis to reduce cytotoxicity and determine effects on specific genes using real-time PCR.
1) Biosensors use immobilized biomolecules like enzymes to detect analytes through optical signals. Stability of immobilized biomolecules is challenging.
2) There are two main types of optical biosensors - those relying on intrinsic optical property changes of biomolecules, and those using optical labels attached to biomolecules.
3) Enzymatic biosensors are highly specific. Glucose biosensors detect glucose concentration through measuring products of the glucose oxidase-catalyzed reaction like hydrogen peroxide or oxygen consumption.
Recombinant antibody mediated delivery of organelle-specific DNA pH sensors a...saheli halder
This document describes the development of a new family of DNA pH sensors that can be targeted to specific intracellular locations using recombinant antibodies. The sensors incorporate a "handle" domain that binds recombinant antibodies identified through a phage display screen. One such antibody is fused to the membrane protein furin, allowing the sensors to be ferried along the furin endocytic pathway inside living cells. By changing the sequence of the pH sensitive domain, sensors were created that span pH ranges from 4 to 7.6. When targeted to cells expressing the antibody-furin chimera, the sensors map the spatiotemporal pH changes within intracellular compartments during furin trafficking. This targeting technique provides a generalizable strategy for delivering DNA nanode
Solid phase extraction is the very popular technique currently available for rapid and selective sample preparation. The versatility of SPE allows use of this technique for many purposes, such as purification, trace enrichment, desalting, and class fractionation and etc.
Quantum dots and application in medical sciencekeyhan *
applications of quantum dots in medicine
Pharmacy and pharmacology
Bioimaiging (in vitro labelling , in vivo imaging)
Tumor & cancer target
Pathogen and toxin detection
Photothermal therapy (PTT)
photodynamic therapy (PDT)
Targeted surgery
Immunoassay
DNA analysis
biological monitoring
drug discovery
Nanoparticles have various applications in modern separation science techniques. They can be used in liquid chromatography, gas chromatography, capillary electrophoresis, microchip electrophoresis, and ion chromatography. Nanoparticles are relatively easy to synthesize and functionalize, and have large surface area to volume ratios ideal for separations. Common nanoparticles used include gold nanoparticles, silica nanoparticles, and magnetic nanoparticles. They have been shown to improve separation efficiency, selectivity, and resolution compared to conventional separation methods. However, while successful in research, nanoparticle-based separations have not been widely adopted in industrial settings.
The document summarizes research on synthesizing phenazine ligands through metal templation. Key points:
1) Phenazine ligands like phendione, DPQ and DPPZ were synthesized through both literature methods and metal templation with cobalt. Metal templation produced higher yields for DPQ and lower impurities for all ligands.
2) PDT was successfully synthesized through cobalt templation for the first time, in just one hour compared to 20 hours for literature methods.
3) The metal templation method overcomes difficult syntheses and is an excellent approach for synthesizing ligands like PDT. Future work will aim to increase PDT yield and purity.
Measuring pKas, logP and Solubility by Automated titrationJon Mole
Presentation by Sirius Analytical covering measurement of pKa, LogP, LogD, Solubility, Supersaturation and precipitation kinetics.
For more details visit www.sirius-analytical.com
How Barcodes Can Be Leveraged Within Odoo 17Celine George
In this presentation, we will explore how barcodes can be leveraged within Odoo 17 to streamline our manufacturing processes. We will cover the configuration steps, how to utilize barcodes in different manufacturing scenarios, and the overall benefits of implementing this technology.
Chapter wise All Notes of First year Basic Civil Engineering.pptxDenish Jangid
Chapter wise All Notes of First year Basic Civil Engineering
Syllabus
Chapter-1
Introduction to objective, scope and outcome the subject
Chapter 2
Introduction: Scope and Specialization of Civil Engineering, Role of civil Engineer in Society, Impact of infrastructural development on economy of country.
Chapter 3
Surveying: Object Principles & Types of Surveying; Site Plans, Plans & Maps; Scales & Unit of different Measurements.
Linear Measurements: Instruments used. Linear Measurement by Tape, Ranging out Survey Lines and overcoming Obstructions; Measurements on sloping ground; Tape corrections, conventional symbols. Angular Measurements: Instruments used; Introduction to Compass Surveying, Bearings and Longitude & Latitude of a Line, Introduction to total station.
Levelling: Instrument used Object of levelling, Methods of levelling in brief, and Contour maps.
Chapter 4
Buildings: Selection of site for Buildings, Layout of Building Plan, Types of buildings, Plinth area, carpet area, floor space index, Introduction to building byelaws, concept of sun light & ventilation. Components of Buildings & their functions, Basic concept of R.C.C., Introduction to types of foundation
Chapter 5
Transportation: Introduction to Transportation Engineering; Traffic and Road Safety: Types and Characteristics of Various Modes of Transportation; Various Road Traffic Signs, Causes of Accidents and Road Safety Measures.
Chapter 6
Environmental Engineering: Environmental Pollution, Environmental Acts and Regulations, Functional Concepts of Ecology, Basics of Species, Biodiversity, Ecosystem, Hydrological Cycle; Chemical Cycles: Carbon, Nitrogen & Phosphorus; Energy Flow in Ecosystems.
Water Pollution: Water Quality standards, Introduction to Treatment & Disposal of Waste Water. Reuse and Saving of Water, Rain Water Harvesting. Solid Waste Management: Classification of Solid Waste, Collection, Transportation and Disposal of Solid. Recycling of Solid Waste: Energy Recovery, Sanitary Landfill, On-Site Sanitation. Air & Noise Pollution: Primary and Secondary air pollutants, Harmful effects of Air Pollution, Control of Air Pollution. . Noise Pollution Harmful Effects of noise pollution, control of noise pollution, Global warming & Climate Change, Ozone depletion, Greenhouse effect
Text Books:
1. Palancharmy, Basic Civil Engineering, McGraw Hill publishers.
2. Satheesh Gopi, Basic Civil Engineering, Pearson Publishers.
3. Ketki Rangwala Dalal, Essentials of Civil Engineering, Charotar Publishing House.
4. BCP, Surveying volume 1
This document provides an overview of wound healing, its functions, stages, mechanisms, factors affecting it, and complications.
A wound is a break in the integrity of the skin or tissues, which may be associated with disruption of the structure and function.
Healing is the body’s response to injury in an attempt to restore normal structure and functions.
Healing can occur in two ways: Regeneration and Repair
There are 4 phases of wound healing: hemostasis, inflammation, proliferation, and remodeling. This document also describes the mechanism of wound healing. Factors that affect healing include infection, uncontrolled diabetes, poor nutrition, age, anemia, the presence of foreign bodies, etc.
Complications of wound healing like infection, hyperpigmentation of scar, contractures, and keloid formation.
Philippine Edukasyong Pantahanan at Pangkabuhayan (EPP) CurriculumMJDuyan
(𝐓𝐋𝐄 𝟏𝟎𝟎) (𝐋𝐞𝐬𝐬𝐨𝐧 𝟏)-𝐏𝐫𝐞𝐥𝐢𝐦𝐬
𝐃𝐢𝐬𝐜𝐮𝐬𝐬 𝐭𝐡𝐞 𝐄𝐏𝐏 𝐂𝐮𝐫𝐫𝐢𝐜𝐮𝐥𝐮𝐦 𝐢𝐧 𝐭𝐡𝐞 𝐏𝐡𝐢𝐥𝐢𝐩𝐩𝐢𝐧𝐞𝐬:
- Understand the goals and objectives of the Edukasyong Pantahanan at Pangkabuhayan (EPP) curriculum, recognizing its importance in fostering practical life skills and values among students. Students will also be able to identify the key components and subjects covered, such as agriculture, home economics, industrial arts, and information and communication technology.
𝐄𝐱𝐩𝐥𝐚𝐢𝐧 𝐭𝐡𝐞 𝐍𝐚𝐭𝐮𝐫𝐞 𝐚𝐧𝐝 𝐒𝐜𝐨𝐩𝐞 𝐨𝐟 𝐚𝐧 𝐄𝐧𝐭𝐫𝐞𝐩𝐫𝐞𝐧𝐞𝐮𝐫:
-Define entrepreneurship, distinguishing it from general business activities by emphasizing its focus on innovation, risk-taking, and value creation. Students will describe the characteristics and traits of successful entrepreneurs, including their roles and responsibilities, and discuss the broader economic and social impacts of entrepreneurial activities on both local and global scales.
Temple of Asclepius in Thrace. Excavation resultsKrassimira Luka
The temple and the sanctuary around were dedicated to Asklepios Zmidrenus. This name has been known since 1875 when an inscription dedicated to him was discovered in Rome. The inscription is dated in 227 AD and was left by soldiers originating from the city of Philippopolis (modern Plovdiv).
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إضغ بين إيديكم من أقوى الملازم التي صممتها
ملزمة تشريح الجهاز الهيكلي (نظري 3)
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تتميز هذهِ الملزمة بعِدة مُميزات :
1- مُترجمة ترجمة تُناسب جميع المستويات
2- تحتوي على 78 رسم توضيحي لكل كلمة موجودة بالملزمة (لكل كلمة !!!!)
#فهم_ماكو_درخ
3- دقة الكتابة والصور عالية جداً جداً جداً
4- هُنالك بعض المعلومات تم توضيحها بشكل تفصيلي جداً (تُعتبر لدى الطالب أو الطالبة بإنها معلومات مُبهمة ومع ذلك تم توضيح هذهِ المعلومات المُبهمة بشكل تفصيلي جداً
5- الملزمة تشرح نفسها ب نفسها بس تكلك تعال اقراني
6- تحتوي الملزمة في اول سلايد على خارطة تتضمن جميع تفرُعات معلومات الجهاز الهيكلي المذكورة في هذهِ الملزمة
واخيراً هذهِ الملزمة حلالٌ عليكم وإتمنى منكم إن تدعولي بالخير والصحة والعافية فقط
كل التوفيق زملائي وزميلاتي ، زميلكم محمد الذهبي 💊💊
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Juneteenth Freedom Day 2024 David Douglas School District
Quantum dots
1. الرحيم الرحمن هللا بسم
Profundización en Química Analítica
Quantum Dots as pH Probes for Study of the Enzyme Kinetics
Ala’ Salem Alnaimat
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2. Outlines: Introduction
- What is Quantum Dots (QDs)?
- Properties of QDs
- Applications of QDs
Objective
Advantages & Disadvantages
Methodology
Results
conclusions
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3. Introduction
What is Quantum Dots (QDs)?
QDs are luminescent semiconductor nanocrystals of an approximately 2–100 nm
( 10-50 atoms) in diameter.
Properties of QDs:
1- high brightness due to the extinction coefficient
2- broad absorption characteristics and a narrow band width in emission spectra.
3- Longer fluorescence lifetime ranging from 10 - 40 ns compared to the organic dyes.
The Quantum Dot
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4. Applications of QDs:
Computing : increase the performance
and storage of computers
Biology: Cell labelling, cancer therapy, and
lymphocyte immunology
Light emitting devices (LOD): displays industry
Photovoltaic devices: increase the efficiency and reduce
the cost of today's typical silicon Photovoltaic cells.
Security Tags: can be detected using the night-vision goggles
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5. Advantages & Disadvantages of QDs
Advantages: water soluble substances. Compared with the
traditional analytical methods based organic dyes using QDs
as pH probes was found to be a convenient, rapid and specific
method for the kinetics studies.
Disadvantages: QDs may be toxic according to its composition
which includes some heavy metals, and also the degradation of
QDs is still unknown specially inside the living organism.
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6. Objective
QDs were used as pH probe for a reaction kinetic study of the hydrolysis
of glycidyl butyrate catalyzed by porcine pancreatic lipase (PPL)
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8. Results
The fluorescence intensity of ZnS QDs linearly decreases with time increasing, which
indicates that QDs can be successfully used as pH probes for enzyme reaction kinetic
study.Time ( a-j): 1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 min
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9. The effect of The emission spectra
of ZnS QDs to different additives.
(a) Ultra pure water; (b) methanol;
(c) PPL; (d) glycidyl butyrate;
(e) glycidol.on the fluorescence
intensity of QDs is investigated
No significant influence of
all these materials on the
fluorescence intensity of QDs
is observed.
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10. conclusions
• The proposed method was found to improve stability,
sensitivity and a monitoring range for determination proton
concentration as compared to the methods based on the organic
dyes.
References:
• Dudu Wua, Zhi Chenb “ZnS quantum dots as pH probes for study of enzyme
reaction kinetics” Enzyme and Microbial Technology 51 (2012) 47– 52.
• Tan Jun, Wang Bochu, Zhu Liancai “ Quantum Dots: A novel tool to discovery”
Pakistan Journal of Biological Science. 9 (5) 917- 922, 2006
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