Presented By- Dr. Hardik Jain, Co-Authors- Dr. Mrunal Patil, Dr. Dhiraj Balwir( Disclosure: Author Has No Financial Interest ), Dr. Vasantrao Pawar Medical College, Nashik
This document discusses surgical induced astigmatism following cataract surgery. It notes that astigmatism has a significant impact on vision and is influenced by surgical technique and incision size and type. Various factors can induce astigmatism including incision location and size, suture type and placement, and wound compression or gape. Evaluating astigmatism involves tools like retinoscopy, keratometry and corneal topography. Managing astigmatism may involve selective suture removal to reduce cylindrical error over time.
Keratoconus is a degenerative eye condition where the cornea thins and changes shape, causing vision problems. The cause is unknown but risk factors include eye rubbing and genetics. Symptoms include progressively worsening vision not fully corrected by glasses. Diagnosis involves examining the cornea shape using keratometry and topography to detect thinning, steepening, and irregular astigmatism. Mild cases may need no treatment, while progressive cases can be managed with contact lenses or corneal cross-linking depending on severity.
Corneal dystrophy is a group of inherited bilateral corneal conditions characterized by progressive corneal opacity. There are several classifications of corneal dystrophy based on the layer of the cornea affected, including epithelial dystrophy affecting the epithelium and basement membrane, Bowman's layer dystrophy, stromal dystrophy affecting the stroma, and Descemet's membrane and endothelial dystrophy affecting the inner layers. Diagnosis involves slit lamp examination to determine the opacity pattern, location, and characteristics in direct and retroillumination. Treatment depends on the severity and type but may include lubricants, therapeutic contact lenses, corneal transplantation, or newer procedures like DSAEK.
This document provides an overview of different types of corneal dystrophies, including their classification, clinical features, histopathology, and management. It discusses epithelial and subepithelial dystrophies, corneal dystrophies of Bowman's layer, stromal corneal dystrophies, and Descemet membrane and endothelial dystrophies. The key points are that corneal dystrophies are inherited, bilateral, and slowly progressive disorders that begin early in life and are characterized by corneal opacification without relationship to environmental factors. Diagnosis involves classification based on the anatomical layer affected and treatment typically involves managing symptoms although surgery may be needed if vision is impaired.
Serous choroidal detachment occurs when fluid accumulates between the choroid and sclera, lifting the choroid. It is often related to low intraocular pressure after surgery or trauma. Hemorrhagic choroidal detachment results from rupture of short posterior ciliary arteries due to trauma, surgery, or increased pressure. Ultrasound shows a smooth dome-shaped elevation and OCT may show retinal pigment epithelium thickening. Management includes cycloplegia, corticosteroids, increasing intraocular pressure, and sometimes choroidal drainage surgery. Prognosis depends on extent of detachment and hemorrhage, with limited detachments having better outcomes.
This document discusses using optical coherence tomography (OCT) to analyze the macula, retinal nerve fiber layer (RNFL), and optic nerve head in patients with glaucoma or suspected glaucoma. It describes how OCT can measure macular thickness, RNFL thickness, and optic disc parameters. Five case studies are presented showing how structural changes seen on OCT correlate with functional defects on visual field tests or clinical findings. The document concludes by mentioning Doppler OCT may help understand the role of blood flow in glaucoma and other optic neuropathies.
Gonioscopy: gonioscopic lenses, principle and clinical aspectsDr Samarth Mishra
This document discusses gonioscopy, which is used to examine the anterior chamber angle. It begins by explaining that the angle cannot be viewed directly due to total internal reflection at the cornea. Gonioscopic lenses eliminate this effect by matching the cornea's refractive index. There are two main types of lenses - indirect lenses use mirrors and direct lenses refract light. The document then describes various gonioscopic lenses and techniques like indentation gonioscopy. It outlines the clinical uses of gonioscopy and provides examples of gonioscopic findings. In summary, the document provides an in-depth overview of gonioscopy equipment, techniques, and applications.
This document summarizes information about Nd:YAG laser capsulotomy procedures. It discusses the laser used, how it works, preoperative assessment, procedure goals and techniques, potential complications, and ways to manage issues like capsulorrhexis contracture and retained lens cortex. The key points are that Nd:YAG laser capsulotomy can treat posterior capsule opacification, careful preoperative evaluation is important, the goal is to create capsulotomy flaps in the periphery to avoid fragments, and complications may include elevated pressure, inflammation, or retinal issues if not performed properly.
This document discusses surgical induced astigmatism following cataract surgery. It notes that astigmatism has a significant impact on vision and is influenced by surgical technique and incision size and type. Various factors can induce astigmatism including incision location and size, suture type and placement, and wound compression or gape. Evaluating astigmatism involves tools like retinoscopy, keratometry and corneal topography. Managing astigmatism may involve selective suture removal to reduce cylindrical error over time.
Keratoconus is a degenerative eye condition where the cornea thins and changes shape, causing vision problems. The cause is unknown but risk factors include eye rubbing and genetics. Symptoms include progressively worsening vision not fully corrected by glasses. Diagnosis involves examining the cornea shape using keratometry and topography to detect thinning, steepening, and irregular astigmatism. Mild cases may need no treatment, while progressive cases can be managed with contact lenses or corneal cross-linking depending on severity.
Corneal dystrophy is a group of inherited bilateral corneal conditions characterized by progressive corneal opacity. There are several classifications of corneal dystrophy based on the layer of the cornea affected, including epithelial dystrophy affecting the epithelium and basement membrane, Bowman's layer dystrophy, stromal dystrophy affecting the stroma, and Descemet's membrane and endothelial dystrophy affecting the inner layers. Diagnosis involves slit lamp examination to determine the opacity pattern, location, and characteristics in direct and retroillumination. Treatment depends on the severity and type but may include lubricants, therapeutic contact lenses, corneal transplantation, or newer procedures like DSAEK.
This document provides an overview of different types of corneal dystrophies, including their classification, clinical features, histopathology, and management. It discusses epithelial and subepithelial dystrophies, corneal dystrophies of Bowman's layer, stromal corneal dystrophies, and Descemet membrane and endothelial dystrophies. The key points are that corneal dystrophies are inherited, bilateral, and slowly progressive disorders that begin early in life and are characterized by corneal opacification without relationship to environmental factors. Diagnosis involves classification based on the anatomical layer affected and treatment typically involves managing symptoms although surgery may be needed if vision is impaired.
Serous choroidal detachment occurs when fluid accumulates between the choroid and sclera, lifting the choroid. It is often related to low intraocular pressure after surgery or trauma. Hemorrhagic choroidal detachment results from rupture of short posterior ciliary arteries due to trauma, surgery, or increased pressure. Ultrasound shows a smooth dome-shaped elevation and OCT may show retinal pigment epithelium thickening. Management includes cycloplegia, corticosteroids, increasing intraocular pressure, and sometimes choroidal drainage surgery. Prognosis depends on extent of detachment and hemorrhage, with limited detachments having better outcomes.
This document discusses using optical coherence tomography (OCT) to analyze the macula, retinal nerve fiber layer (RNFL), and optic nerve head in patients with glaucoma or suspected glaucoma. It describes how OCT can measure macular thickness, RNFL thickness, and optic disc parameters. Five case studies are presented showing how structural changes seen on OCT correlate with functional defects on visual field tests or clinical findings. The document concludes by mentioning Doppler OCT may help understand the role of blood flow in glaucoma and other optic neuropathies.
Gonioscopy: gonioscopic lenses, principle and clinical aspectsDr Samarth Mishra
This document discusses gonioscopy, which is used to examine the anterior chamber angle. It begins by explaining that the angle cannot be viewed directly due to total internal reflection at the cornea. Gonioscopic lenses eliminate this effect by matching the cornea's refractive index. There are two main types of lenses - indirect lenses use mirrors and direct lenses refract light. The document then describes various gonioscopic lenses and techniques like indentation gonioscopy. It outlines the clinical uses of gonioscopy and provides examples of gonioscopic findings. In summary, the document provides an in-depth overview of gonioscopy equipment, techniques, and applications.
This document summarizes information about Nd:YAG laser capsulotomy procedures. It discusses the laser used, how it works, preoperative assessment, procedure goals and techniques, potential complications, and ways to manage issues like capsulorrhexis contracture and retained lens cortex. The key points are that Nd:YAG laser capsulotomy can treat posterior capsule opacification, careful preoperative evaluation is important, the goal is to create capsulotomy flaps in the periphery to avoid fragments, and complications may include elevated pressure, inflammation, or retinal issues if not performed properly.
This document provides information about ectopia lentis, or displacement of the crystalline lens. It begins with classifications of ectopia lentis based on location and etiology. Congenital causes like Marfan syndrome and homocystinuria are described. Presentation, examination findings, complications, workup, and management approaches are outlined. Surgical techniques depend on degree and location of lens subluxation/dislocation and may involve lens removal with or without intraocular lens implantation. Management of subluxated lenses in children poses additional challenges due to risk of complications with contact lenses or suture-fixated intraocular lenses.
This document discusses various methods for assessing the anterior chamber angle, including subjective tests like the oblique flashlight test and Van Herrick's technique, as well as objective tests like gonioscopy, ultrasound biomicroscopy (UBM), and anterior segment optical coherence tomography (AS-OCT). Gonioscopy is considered the reference standard but can be subjective, while UBM and AS-OCT provide high resolution cross-sectional images of the angle but have limitations like requiring specialized equipment. No single test is perfect, and gonioscopy remains essential for glaucoma evaluation and management despite advances in imaging technology.
The document provides information on axial length measurement techniques using ultrasound (A-scan) biometry. It discusses average axial lengths, accuracy of measurements, examination procedure, potential sources of error for different techniques, instrument settings, and special measurement considerations. Key points include:
- The average axial length of a normal eye is 23.06mm, ranging mostly from 22-24.5mm.
- Accuracy of A-scan ultrasound is ±0.1mm. Differences between eyes should be ≤0.3mm.
- Potential sources of error include corneal compression, fluid excess, misalignment, inappropriate eye type settings.
- Gates, gain, and eye type settings impact accuracy and must be optimized.
- Special
Multifocal IOLs provide both near and distance vision without glasses by utilizing concentric zones of different optical powers (refractive MFIOLs) or diffractive properties to split light between two focal points. While eliminating need for glasses, they can cause visual side effects like glare and reduced contrast sensitivity. Careful patient selection and counseling, accurate biometry and surgical technique are important for successful multifocal IOL implantation outcomes.
This document provides information about cone and rod dystrophy (CORD), including its genetics, clinical presentation, classification, and mechanisms. It discusses how CORD is a genetically heterogeneous group of inherited retinal dystrophies involving both cone and rod photoreceptors. The document outlines the typical stages and symptoms of CORD and compares it to other conditions like achromatopsia. It also describes syndromic forms of CORD and provides a classification system for CORD based on genetics.
This document discusses non-penetrating glaucoma surgery techniques that facilitate the drainage of aqueous humor through the trabecular meshwork and Schlemm's canal without opening the anterior chamber. It describes several procedures including deep sclerectomy, viscocanalostomy, canaloplasty, ab-externo trabeculectomy, and laser trabecular ablation. The goal is to bypass the highest resistance point to outflow in the juxtacanalicular meshwork. Advantages include lower risks of complications like hypotony compared to penetrating surgeries. Indications and contraindications are provided for various non-penetrating glaucoma procedures.
This document discusses choroidal coloboma, beginning with definitions and epidemiology. It describes the embryonic development of the eye and how failure of fusion of the embryonic fissure can result in coloboma. Types of coloboma are classified based on location and presence of other anomalies. Complications like retinal detachment are discussed. Management of cataracts and other ocular issues in the context of coloboma are covered. The prognosis depends on factors like presence of microphthalmos, corneal diameter, and type and timing of surgery.
This document discusses transpupillary thermotherapy (TTT), a technique that uses low-level heat delivered through the pupil to treat conditions like choroidal neovascularization (CNV), choroidal melanoma, and retinoblastoma. TTT works by inducing tumor necrosis or occlusion of neovascular vessels via localized hyperthermia above 42°C. The document outlines the laser parameters used to treat CNV via TTT, noting that a pilot study found 19% of patients experienced improved vision, 56% had no change, and 25% had declining vision, while 94% saw reduced exudation. TTT is currently being used and studied as a treatment for several ocular diseases.
This document discusses the embryology and anatomy of the cornea. It describes how the cornea develops from surface ectoderm in the 4th-5th week of gestation, with mesenchymal cells forming the stroma and endothelium. The cornea continues developing through the fetal period, with layers such as Bowman's membrane forming between 12-26 weeks. The document also discusses the cellular components, functions, and common congenital anomalies of the cornea, including microcornea, megalocornea, cornea plana, keratoconus, and others.
Ultrasound biomicroscopy (UBM) provides high-resolution imaging of ocular structures in the anterior segment of the eye using 50 MHz ultrasound. UBM allows visualization of tissues like the ciliary body and zonules that are not visible by slit lamp examination. UBM can be used to qualitatively and quantitatively evaluate the anterior segment structures and has applications in diagnosing and monitoring conditions like glaucoma, corneal diseases, tumors, and intraocular lenses. While UBM provides excellent detail, it has limitations including only being able to image about 5mm into the eye and requiring contact with the eye, unlike anterior segment OCT which is non-contact.
Update knowledge about Muntifocal IOL made by Asaduzzaman
Working as Associate Optometrist in Ispahani Islamia Eye Institute &Hospita, Dhaka 1215
Email:asad.optom92@yaho. com
This document discusses the evaluation of ptosis, or drooping of the eyelids. It begins by defining ptosis and distinguishing between true and pseudo ptosis. True ptosis is classified as acquired or congenital, with acquired further divided into neurogenic, myogenic, aponeurotic, and mechanical types. The evaluation of ptosis involves a thorough history, measurement of margin-reflex distance, palpebral fissure height, levator function, and upper lid crease. Additional tests include assessing for fatigability, Cogan's twitch sign, and jaw winking phenomenon. Confirmatory tests include the ice test and edrophonium (Tensilon) test. Treatment options mentioned include eyelid
To know Humphrey visual field analyser
To know about various types of perimetry
To identify field defect
To recognize that field defect is due to glaucoma or neurological lesion
To know that field defect is progressive or not
Interpretation of HVFA
This document discusses the morphological changes that occur in the optic nerve head and retinal nerve fiber layer in glaucoma. It describes the various patterns of glaucomatous optic nerve damage including focal notching, concentric cupping, saucerization, and advanced cupping. Features that indicate glaucomatous damage include neuroretinal rim thinning, disc hemorrhages, and changes in the retinal vasculature around the optic disc. Evaluation of the optic nerve head is important for early detection of glaucoma before visual field loss occurs.
Pigmentary glaucoma - Dr Shylesh B DabkeShylesh Dabke
Pigment Dispersion Syndrome (PDS) involves abnormal amounts of pigment released from the iris that deposit throughout the eye. It can sometimes progress to Pigmentary Glaucoma (PG). PDS is more common in young, white, myopic males and has genetic links. Theories for its pathogenesis include mechanical abrasion between the iris and lens zonules or abnormal iris cell degeneration. Over time, PDS can cause increased eye pressure and vision loss from PG if not properly treated with medications, laser procedures, or surgery.
This document discusses Duane retraction syndrome, an ocular motility disorder characterized by defective horizontal eye movement and narrowing of the eyelid when the eye adducts. It is usually unilateral and sporadic, though some familial cases are due to mutations in the CHN1 gene. There are four types described based on limitations of adduction and abduction. Duane syndrome can occur with other syndromes and limb abnormalities. Clinical features and differential diagnosis are provided. Surgical treatment depends on the type of strabismus and may include recession or resection of extraocular muscles.
An epiretinal membrane is an avascular fibrocellular membrane that grows on the inner surface of the retina, causing macular dysfunction. It consists of various cell types and collagen. Symptoms include blurry vision and metamorphopsia. Observation is usually sufficient for mild cases, but surgery is recommended for significant vision loss or distortion. Peeling the membrane improves vision in most cases, though cataracts are a common complication. Prognosis is better when pre-op vision is good and the duration of symptoms is short.
IOL power calculation is challenging in eyes with prior refractive surgery or other special situations. In eyes with prior radial keratotomy, standard keratometry overestimates corneal power due to flattening outside the central optical zone. Multiple methods of IOL power calculation should be used, including topography to measure the flattest central corneal power. A study comparing methods in eyes with prior RK found IOL power calculation using topographic keratometry was least accurate compared to formulas from the ESCRS calculator. No single method provided reliable results, highlighting the difficulty in IOL power calculation for eyes with prior refractive surgery.
Keratoconus is a non-inflammatory thinning of the cornea that causes it to take on a conical shape. It typically develops in adolescence and causes vision impairment due to irregular astigmatism. It is classified into four stages based on refractive error, corneal thickness and shape. While the exact cause is unknown, theories include genetic and enzymatic factors. It is often associated with eye rubbing and connective tissue disorders. Clinical features include corneal thinning, Fleischer's ring, Munson's sign, and scarring in advanced cases. Diagnosis involves topography, pachymetry and biomicroscopy to detect corneal shape changes.
This document provides an overview of Acute Retinal Necrosis Syndrome (ARN), a rare but potentially blinding condition caused by herpes viruses like varicella zoster virus and herpes simplex virus. It discusses the clinical presentation, course, risk factors, diagnosis, differential diagnosis and treatment of ARN. Key points include:
1) ARN causes necrotizing retinitis and vasculitis that can lead to retinal detachment if left untreated.
2) It is typically treated with high-dose intravenous antiviral medications like acyclovir followed by long-term oral antivirals to prevent involvement of the second eye.
3) Prognosis is poor if
Optics for Post Graduate Ophthalmology Cairo universityYasser Saif
This document provides information about an ophthalmology postgraduate program. It lists Prof Dr Sayed S E H Saif as the expert leading the program, noting that he is an ex-Dean of NILE university and a professor of ophthalmology at Cairo University.
Ectopia lentis refers to displacement of the lens from its normal position. It can be acquired through trauma or tumors, or inherited through isolated familial forms or associated with systemic syndromes like Marfan syndrome, Weill-Marchesani syndrome, and Homocystinuria. Treatment options depend on the cause and symptoms but may include spectacle correction, laser zonulysis to displace the lens, or surgical removal of the lens.
This document provides information about ectopia lentis, or displacement of the crystalline lens. It begins with classifications of ectopia lentis based on location and etiology. Congenital causes like Marfan syndrome and homocystinuria are described. Presentation, examination findings, complications, workup, and management approaches are outlined. Surgical techniques depend on degree and location of lens subluxation/dislocation and may involve lens removal with or without intraocular lens implantation. Management of subluxated lenses in children poses additional challenges due to risk of complications with contact lenses or suture-fixated intraocular lenses.
This document discusses various methods for assessing the anterior chamber angle, including subjective tests like the oblique flashlight test and Van Herrick's technique, as well as objective tests like gonioscopy, ultrasound biomicroscopy (UBM), and anterior segment optical coherence tomography (AS-OCT). Gonioscopy is considered the reference standard but can be subjective, while UBM and AS-OCT provide high resolution cross-sectional images of the angle but have limitations like requiring specialized equipment. No single test is perfect, and gonioscopy remains essential for glaucoma evaluation and management despite advances in imaging technology.
The document provides information on axial length measurement techniques using ultrasound (A-scan) biometry. It discusses average axial lengths, accuracy of measurements, examination procedure, potential sources of error for different techniques, instrument settings, and special measurement considerations. Key points include:
- The average axial length of a normal eye is 23.06mm, ranging mostly from 22-24.5mm.
- Accuracy of A-scan ultrasound is ±0.1mm. Differences between eyes should be ≤0.3mm.
- Potential sources of error include corneal compression, fluid excess, misalignment, inappropriate eye type settings.
- Gates, gain, and eye type settings impact accuracy and must be optimized.
- Special
Multifocal IOLs provide both near and distance vision without glasses by utilizing concentric zones of different optical powers (refractive MFIOLs) or diffractive properties to split light between two focal points. While eliminating need for glasses, they can cause visual side effects like glare and reduced contrast sensitivity. Careful patient selection and counseling, accurate biometry and surgical technique are important for successful multifocal IOL implantation outcomes.
This document provides information about cone and rod dystrophy (CORD), including its genetics, clinical presentation, classification, and mechanisms. It discusses how CORD is a genetically heterogeneous group of inherited retinal dystrophies involving both cone and rod photoreceptors. The document outlines the typical stages and symptoms of CORD and compares it to other conditions like achromatopsia. It also describes syndromic forms of CORD and provides a classification system for CORD based on genetics.
This document discusses non-penetrating glaucoma surgery techniques that facilitate the drainage of aqueous humor through the trabecular meshwork and Schlemm's canal without opening the anterior chamber. It describes several procedures including deep sclerectomy, viscocanalostomy, canaloplasty, ab-externo trabeculectomy, and laser trabecular ablation. The goal is to bypass the highest resistance point to outflow in the juxtacanalicular meshwork. Advantages include lower risks of complications like hypotony compared to penetrating surgeries. Indications and contraindications are provided for various non-penetrating glaucoma procedures.
This document discusses choroidal coloboma, beginning with definitions and epidemiology. It describes the embryonic development of the eye and how failure of fusion of the embryonic fissure can result in coloboma. Types of coloboma are classified based on location and presence of other anomalies. Complications like retinal detachment are discussed. Management of cataracts and other ocular issues in the context of coloboma are covered. The prognosis depends on factors like presence of microphthalmos, corneal diameter, and type and timing of surgery.
This document discusses transpupillary thermotherapy (TTT), a technique that uses low-level heat delivered through the pupil to treat conditions like choroidal neovascularization (CNV), choroidal melanoma, and retinoblastoma. TTT works by inducing tumor necrosis or occlusion of neovascular vessels via localized hyperthermia above 42°C. The document outlines the laser parameters used to treat CNV via TTT, noting that a pilot study found 19% of patients experienced improved vision, 56% had no change, and 25% had declining vision, while 94% saw reduced exudation. TTT is currently being used and studied as a treatment for several ocular diseases.
This document discusses the embryology and anatomy of the cornea. It describes how the cornea develops from surface ectoderm in the 4th-5th week of gestation, with mesenchymal cells forming the stroma and endothelium. The cornea continues developing through the fetal period, with layers such as Bowman's membrane forming between 12-26 weeks. The document also discusses the cellular components, functions, and common congenital anomalies of the cornea, including microcornea, megalocornea, cornea plana, keratoconus, and others.
Ultrasound biomicroscopy (UBM) provides high-resolution imaging of ocular structures in the anterior segment of the eye using 50 MHz ultrasound. UBM allows visualization of tissues like the ciliary body and zonules that are not visible by slit lamp examination. UBM can be used to qualitatively and quantitatively evaluate the anterior segment structures and has applications in diagnosing and monitoring conditions like glaucoma, corneal diseases, tumors, and intraocular lenses. While UBM provides excellent detail, it has limitations including only being able to image about 5mm into the eye and requiring contact with the eye, unlike anterior segment OCT which is non-contact.
Update knowledge about Muntifocal IOL made by Asaduzzaman
Working as Associate Optometrist in Ispahani Islamia Eye Institute &Hospita, Dhaka 1215
Email:asad.optom92@yaho. com
This document discusses the evaluation of ptosis, or drooping of the eyelids. It begins by defining ptosis and distinguishing between true and pseudo ptosis. True ptosis is classified as acquired or congenital, with acquired further divided into neurogenic, myogenic, aponeurotic, and mechanical types. The evaluation of ptosis involves a thorough history, measurement of margin-reflex distance, palpebral fissure height, levator function, and upper lid crease. Additional tests include assessing for fatigability, Cogan's twitch sign, and jaw winking phenomenon. Confirmatory tests include the ice test and edrophonium (Tensilon) test. Treatment options mentioned include eyelid
To know Humphrey visual field analyser
To know about various types of perimetry
To identify field defect
To recognize that field defect is due to glaucoma or neurological lesion
To know that field defect is progressive or not
Interpretation of HVFA
This document discusses the morphological changes that occur in the optic nerve head and retinal nerve fiber layer in glaucoma. It describes the various patterns of glaucomatous optic nerve damage including focal notching, concentric cupping, saucerization, and advanced cupping. Features that indicate glaucomatous damage include neuroretinal rim thinning, disc hemorrhages, and changes in the retinal vasculature around the optic disc. Evaluation of the optic nerve head is important for early detection of glaucoma before visual field loss occurs.
Pigmentary glaucoma - Dr Shylesh B DabkeShylesh Dabke
Pigment Dispersion Syndrome (PDS) involves abnormal amounts of pigment released from the iris that deposit throughout the eye. It can sometimes progress to Pigmentary Glaucoma (PG). PDS is more common in young, white, myopic males and has genetic links. Theories for its pathogenesis include mechanical abrasion between the iris and lens zonules or abnormal iris cell degeneration. Over time, PDS can cause increased eye pressure and vision loss from PG if not properly treated with medications, laser procedures, or surgery.
This document discusses Duane retraction syndrome, an ocular motility disorder characterized by defective horizontal eye movement and narrowing of the eyelid when the eye adducts. It is usually unilateral and sporadic, though some familial cases are due to mutations in the CHN1 gene. There are four types described based on limitations of adduction and abduction. Duane syndrome can occur with other syndromes and limb abnormalities. Clinical features and differential diagnosis are provided. Surgical treatment depends on the type of strabismus and may include recession or resection of extraocular muscles.
An epiretinal membrane is an avascular fibrocellular membrane that grows on the inner surface of the retina, causing macular dysfunction. It consists of various cell types and collagen. Symptoms include blurry vision and metamorphopsia. Observation is usually sufficient for mild cases, but surgery is recommended for significant vision loss or distortion. Peeling the membrane improves vision in most cases, though cataracts are a common complication. Prognosis is better when pre-op vision is good and the duration of symptoms is short.
IOL power calculation is challenging in eyes with prior refractive surgery or other special situations. In eyes with prior radial keratotomy, standard keratometry overestimates corneal power due to flattening outside the central optical zone. Multiple methods of IOL power calculation should be used, including topography to measure the flattest central corneal power. A study comparing methods in eyes with prior RK found IOL power calculation using topographic keratometry was least accurate compared to formulas from the ESCRS calculator. No single method provided reliable results, highlighting the difficulty in IOL power calculation for eyes with prior refractive surgery.
Keratoconus is a non-inflammatory thinning of the cornea that causes it to take on a conical shape. It typically develops in adolescence and causes vision impairment due to irregular astigmatism. It is classified into four stages based on refractive error, corneal thickness and shape. While the exact cause is unknown, theories include genetic and enzymatic factors. It is often associated with eye rubbing and connective tissue disorders. Clinical features include corneal thinning, Fleischer's ring, Munson's sign, and scarring in advanced cases. Diagnosis involves topography, pachymetry and biomicroscopy to detect corneal shape changes.
This document provides an overview of Acute Retinal Necrosis Syndrome (ARN), a rare but potentially blinding condition caused by herpes viruses like varicella zoster virus and herpes simplex virus. It discusses the clinical presentation, course, risk factors, diagnosis, differential diagnosis and treatment of ARN. Key points include:
1) ARN causes necrotizing retinitis and vasculitis that can lead to retinal detachment if left untreated.
2) It is typically treated with high-dose intravenous antiviral medications like acyclovir followed by long-term oral antivirals to prevent involvement of the second eye.
3) Prognosis is poor if
Optics for Post Graduate Ophthalmology Cairo universityYasser Saif
This document provides information about an ophthalmology postgraduate program. It lists Prof Dr Sayed S E H Saif as the expert leading the program, noting that he is an ex-Dean of NILE university and a professor of ophthalmology at Cairo University.
Ectopia lentis refers to displacement of the lens from its normal position. It can be acquired through trauma or tumors, or inherited through isolated familial forms or associated with systemic syndromes like Marfan syndrome, Weill-Marchesani syndrome, and Homocystinuria. Treatment options depend on the cause and symptoms but may include spectacle correction, laser zonulysis to displace the lens, or surgical removal of the lens.
Hyphema refers to blood in the anterior chamber of the eye. It is typically caused by trauma that tears blood vessels in the iris, ciliary body, or trabecular meshwork. Hyphemas are classified based on their etiology (cause), amount of bleeding, and location in the eye. Treatment involves resting the eye, using cycloplegic eye drops to prevent inflammation, and occasionally surgically removing blood if it causes increased pressure or vision loss. The prognosis is generally good if the hyphema involves less than half the anterior chamber, but can be poorer for larger bleeds.
This document provides an overview of eye anatomy and physiology as well as clinical assessment of the eye. It discusses the anatomy of the eyelids, muscles, nerves, and retina. It describes types of eye movements including saccades, smooth pursuit, and convergence. Reflexes like the light and accommodation reflex are also covered. The document outlines how to examine the eyes, eyelids, conjunctiva, visual acuity, fields, movements, and pupils. Causes and features of cranial nerve palsies are summarized.
It is a brief description of the Neurofibromatosis genetic disorder.
The content include:
*Definition of Neurofibromatosis
*Symptoms of Neurofibromatosis
*Causes & Risk factors
*Complications
*Tests and diagnosis
*Treatments
References:
Robbins Basic Pathology, 9th Edition.
Medical Genetics, 4th Edition.
Myoclinic.
This document discusses the anatomy and innervation of the extraocular muscles, as well as some common pediatric ophthalmological conditions. It describes the origins and insertions of the six extraocular muscles, and provides their actions and nerve supply. It then covers topics such as cranial nerve palsies, examining visual acuity in children, amblyopia, squints, leucocoria, retinopathy of prematurity, congenital defects, and infections.
This document provides an overview of neuro-ophthalmology and discusses various topics including vision loss, visual field defects, diplopia, supranuclear ocular motility disorders, and abnormal eye movements. It defines neuro-ophthalmology as diseases of the eye and related neurological structures. It describes the anatomy and pathways involved in various eye movements like saccades, smooth pursuit, and vestibulo-ocular reflex. It also discusses lesions that can cause abnormalities in these eye movements.
The most common presenting complaint of Ophthalmology in Emergency dept. is Foreign body sensation, so just to recall the basics of Ophthalm in ED, read the following PPT.
The document discusses refractive surgeries and provides details on LASIK (Laser-Assisted In Situ Keratomileusis) specifically. It summarizes that LASIK combines lamellar corneal surgery using a microkeratome to create a corneal flap with excimer laser ablation of corneal stroma beneath the flap. The procedure involves creating a corneal flap using a microkeratome, ablating the stroma with an excimer laser according to a calculated profile, and repositioning the flap. Complications are minimized as the flap protects underlying tissues from the laser.
This document summarizes different types of corneal refractive surgery procedures. It describes the anatomy and physiology of the cornea, including its layers and shape. It then discusses various laser eye surgery procedures like LASIK, PRK, LASEK, Epi-LASIK, and intrastromal corneal ring implants. For each procedure, it provides a brief overview and lists the advantages and disadvantages. The goal of these surgeries is to correct refractive errors like myopia, hyperopia, and astigmatism by reshaping the cornea through ablation or incisions.
Ocular manifestations of systemic diseaseRiyad Banayot
The document discusses various ocular manifestations of systemic diseases. It covers categories of systemic diseases that can affect the eyes such as congenital, vascular, endocrine/metabolic, autoimmune, infectious, and neoplastic diseases. It provides details on eye examinations and discusses specific diseases like diabetes mellitus, hypertension, migraines, and various blood disorders; explaining their effects on the eyes including retinopathy, vascular changes, and vision loss. Diabetes is highlighted as the most common cause of blindness, with details on proliferative and non-proliferative retinopathy.
This document provides an overview of ocular pharmacology, including drug delivery methods to the eyes, factors influencing drug penetration, and common drug classes used for ocular conditions. Topical drops, ointments, and periocular injections are described as local delivery methods. Systemic administration through oral or intravenous routes is also discussed. Common drug classes covered include antibiotics, antivirals, antifungals, glaucoma medications, anti-inflammatories, and diagnostic agents. Side effects and indications for various drugs are highlighted.
This document summarizes various optic nerve head (ONH) abnormalities, causes of ONH swelling, and lesions that can occur at the chiasm and retrochiasmally. It describes conditions such as optic disc coloboma, tilted disc, myelinated nerve fibers, optic disc drusen, papilledema, anterior ischemic optic neuropathy, pituitary tumors, meningiomas, craniopharyngiomas, aneurysms, and gliomas; and how these present with features like visual field defects, optic atrophy, and visual loss. Lesions are discussed based on their location in the optic nerve, chiasm, optic tract, lateral geniculate nucleus, temporal lobe, parietal lobe, and occ
Retinal vasculitis is an inflammatory eye disease involving the retinal vessels that can occur due to infectious, neoplastic, or systemic inflammatory disorders. It is detected clinically using fundus fluorescein angiography. It can lead to leakage and exudation from affected vessels, as well as occlusion causing cotton-wool spots, edema, hemorrhages, and retinal infarction. Late sequelae include vitreous hemorrhage, tractional retinal detachment, neovascular glaucoma, and rubeosis iridis. Retinopathy of prematurity is a disease affecting the retinas of premature infants that ranges from mild cases to severe cases causing bilateral blindness. It results from an initial vasocon
Sympathetic Ophthalmitis With Subretinal Fibrosis, An Uncommon PresentationDr. Jagannath Boramani
Presented by- Dr. Saurabh Dhewale, Co-authors- Dr. Ajit Khune, Dr. Dhiraj Balwir ( Disclosure: Author has no financial interest ) Dr. Vasantrao Pawar Medical College, Nashik
A 44-year-old woman presented with sudden vision loss and headache in her right eye. She had a history of multiple sclerosis but examination revealed occlusive retinal arteritis. Testing found she was HLA-B51 positive, leading to a diagnosis of possible Behcet's disease. She was treated with intravenous steroids followed by oral steroids, resulting in resolution of inflammation and visual recovery. Behcet's disease is a multisystem vasculitis characterized by recurrent oral and genital ulcers that can cause ocular inflammation including retinal vasculitis.
- Orbital cellulitis is a serious infection of the orbital tissues that does not involve the globe itself. It is most commonly caused by bacterial infection spreading from the paranasal sinuses.
- Physical examination includes assessing vision, eye movements, proptosis, pupil function, and examining the orbit, eyelids and anterior/posterior segments for signs of infection or complications.
- Early diagnosis and treatment with intravenous antibiotics is important to prevent vision loss or life-threatening intracranial infections.
Polypoidal choroidal vasculopathy (PCV) is a type of macular degeneration characterized by abnormal choroidal blood vessels that bulge outward forming polyp-like structures. It shares similarities with neovascular age-related macular degeneration but may have distinct pathogenesis involving disruption of choroidal vascular smooth muscle cells. PCV predominantly affects Asians and is a leading cause of vision loss in this population. Diagnosis is made using indocyanine green angiography which clearly visualizes the abnormal polypoidal choroidal vessels. Treatment options include laser photocoagulation, photodynamic therapy, anti-VEGF drugs, and combinations with the goal of resolving fluid, hemorrhage and regressing the poly
Background: Idiopathic Macular Telangiectasia type 2 (IMT2) is a relatively uncommon clinical condition with an estimated prevalence of 1% within the general population. This condition can be challenging to precisely identify in early stages but advancements in clinical imaging to include fl uorescein angiography and Optical Coherence Tomography Angiography (OCTA) can allow for timely diagnosis and prompt intervention that may leads to improved long-term clinical outcomes. Emerging literature has recognized the role of Macular
Pigment (MP) in IMT2 in terms of Henle fi ber layer deposition mechanisms and potential mitigation of infl ammatory and oxidative stress. Primary care optometrists are in a unique position to facilitate early detection and manage through close evaluation and individualized lutein supplementation
This document provides information on peripheral ulcerative keratitis (PUK), including its causes, pathogenesis, clinical presentation, diagnosis, and treatment. PUK can be caused by infectious, autoimmune, or inflammatory processes that lead to corneal melting and ulceration. It is characterized by sloughing of the corneal epithelium and keratolysis. Diagnostic testing aims to identify any underlying infectious, autoimmune, or inflammatory conditions. Treatment involves topical corticosteroids, conjunctival resection, systemic immunosuppression, and additional surgeries depending on severity and etiology. Mooren's ulcer is a rare type of PUK that is typically unilateral and responsive to local therapies.
Central retinal vein occlusion occurs when the central retinal vein becomes blocked, disrupting blood flow out of the retina. It can be caused by physical blockage at the lamina cribrosa or hemodynamic factors that obstruct blood flow. Histopathology shows occlusion at or behind the lamina cribrosa. Risk factors include hypertension, diabetes, glaucoma, and low physical activity. Investigations may include blood tests, imaging like fluorescein angiography, and screening for thrombophilias in younger patients. Features include retinal hemorrhages, edema, and delayed venous filling on angiography. Prognosis is generally poor for ischemic cases due to vision loss from macular edema, nonperfusion, and neovascular
Retinal arterial obstructions can manifest as central retinal artery obstruction (most common), branch retinal artery obstruction, or chorioretinal artery obstruction. The document discusses the history, etiology, clinical features, investigations, management, and prognosis of these conditions. Common causes include emboli (cholesterol, calcific), atherosclerosis, hypertension, and giant cell arteritis. Clinical features include sudden visual loss, afferent pupillary defect, and pale retina. Investigations include fluorescein angiography and ultrasound. Management involves ocular massage, oxygen, fibrinolytics, and treating underlying conditions. Prognosis depends on location and severity of obstruction.
Retinal arterial obstructions can manifest as central retinal artery obstruction (most common), branch retinal artery obstruction, or chorioretinal artery obstruction. The document discusses the history, etiology, clinical features, investigations, management, and prognosis of these conditions. Common causes include emboli (cholesterol, calcific), atherosclerosis, hypertension, and diabetes. Clinical features may include sudden visual loss, afferent pupillary defect, pale retina, and cherry red spot. Investigations include fluorescein angiography and ultrasound. Management involves ocular massage, oxygen, fibrinolytics, and treating underlying conditions. Prognosis depends on location and severity of obstruction.
This document presents a case report of a 55-year-old man who presented with sudden vision loss in his right eye. On examination, he was found to have signs consistent with central retinal artery occlusion (CRAO), including a cherry red spot and attenuated retinal arterioles. The patient had risk factors of hypertension and smoking. He was informed that the visual prognosis is generally poor for CRAO presenting more than 48 hours after onset. He was referred to a cardiologist given the risk of life-threatening cardiac complications associated with CRAO. The document then reviews the epidemiology, causes, clinical features, investigations, and management approaches for CRAO, emphasizing the importance of prompt referral for evaluation of underlying cardiac conditions
Central serous retinopathy (CSR) is characterized by a serous retinal detachment in the macula due to leakage of fluid from the choroidal vasculature through the retinal pigment epithelium. It typically affects men in their 40s and 50s and can be associated with stress, corticosteroid use, hypertension, and type A personality. While often self-limiting, CSR can become chronic and cause long-lasting visual impairment without treatment. Management options include observation, stress reduction, oral medications like acetazolamide or ketoconazole to lower cortisol levels, and photodynamic therapy for severe or chronic cases.
Pachychoroid spectrum of disease now also include central serous chorioretinopathy. The presentation include history, pathogenesis, clinical features, diffrential and treatment of CSCR
Cscr ( central serous chorioretinopathy )Vinitkumar MJ
Central serous chorioretinopathy (CSCR) is characterized by spontaneous serous detachment of the neurosensory retina in the macular region. It typically affects young to middle-aged males and is associated with type A personality and steroid use. The leading pathogenesis theory is choroidal vascular hyperpermeability causing a breach in the outer blood-retinal barrier and leakage of fluid. On examination, CSCR presents as mild macular elevation with or without retinal pigment epithelium detachment. It usually resolves spontaneously but can recur in 30-50% of cases.
Cystoid macular edema (CME) refers to fluid collection in the macula and is a complication of ocular surgery,
This document provides an overview of optic neuritis, including its:
- Anatomy of the optic nerve and its coverings.
- Microscopy and physiology of the optic nerve.
- Blood supply to the optic nerve.
- Parts of the optic nerve from intracanalicular to intracranial segments.
- Clinical features, signs, investigations, and treatment of optic neuritis, including results from the Optic Neuritis Treatment Trial.
case report.This is a 60 years old female patient, a known Glaucoma patient:pptxfajrimohammed
The document discusses various causes of unilateral acute granulomatous anterior uvitis with high intraocular pressure (IOP). It describes conditions like glaucomatocyclitic crisis, Fuchs heterochromic iridocyclitis, herpes zoster or simplex-associated uveitis, phacolytic and phacoantigenic glaucoma, and ciliary body inflammation and rotation with angle closure glaucoma that can lead to these symptoms. It also discusses evaluating and managing patients with uveitis and elevated pressure, including recognizing underlying syndromes, controlling IOP and inflammation, and addressing specific conditions like Fuchs heterochromic iridocyclitis and herpetic uveitis.
Leukocoria ( or white pupillary reflex) is an abnormal white reflection from the eye.
Leukocoria is a medical sign for a number of several conditions.
- this presentation at annual conference of the Ophthalmic department, faculty of medicine - Al-Azhar University in association with DOS & EOS Cairo, Egypt January 2017
Urrets-Zavalia Syndrome (UZS) is characterized by a fixed, dilated pupil following penetrating keratoplasty (PKP) for keratoconus. The syndrome was first described in 1963 and is thought to be caused by iris ischemia and acute rise in intraocular pressure during or after surgery. Risk factors include the use of mydriatic agents, elevated IOP, presence of keratoconus, and inflammation. Prevention focuses on maintaining a deep anterior chamber and avoiding iris trauma during PKP. Management includes treatments to lower IOP if elevated, with reconstructive surgery if symptoms from the fixed, dilated pupil are present.
Orientation,history taking and examinatio.pptsultanovasits
The document outlines an orientation course for ophthalmology residents that covers various topics including history taking, examination techniques, common diseases and emergencies. It details the objectives of the course, components such as lectures and clinical sessions, assessment methods, recommended textbooks and electronic resources. Key examination techniques discussed include visual acuity testing, external eye examination, motility evaluation, slit lamp biomicroscopy, tonometry and ophthalmoscopy.
A 43-year-old man presented with a corneal thermal injury to his left eye from an incense stick burn 15 days prior. He had high irregular astigmatism of 10.07D initially which regressed over 19 months with topical medications and no refractive correction. The astigmatism reduced to 7.22D after 4 months and 0.81D after 19 months with improvement in visual acuity. Corneal thermal injuries can cause significant irregular astigmatism due to localized collagen shrinkage, but spontaneous regression is likely over time with conservative management.
(1) Topical cyclosporine 0.1% was evaluated in a prospective clinical trial for the treatment of vernal catarrh. (2) 24 patients with mild, moderate, or severe vernal catarrh were treated with topical cyclosporine 0.1% 4 times daily for 3 months and evaluated after 7 days, 1 month, and 3 months. (3) Statistically significant improvement was seen in symptoms and signs for mild and moderate cases, but not for severe cases, suggesting topical cyclosporine 0.1% is an effective and safe treatment for mild to moderate vernal catarrh.
This document reports on a case study of an 8-year-old male child diagnosed with Goldenhar syndrome. Goldenhar syndrome is a rare birth defect affecting the development of structures derived from the first and second branchial arches. The child presented with a dermolipoma (fatty growth) in his right eye, preauricular tags on both ears, and facial asymmetry. Examination found no other abnormalities. The dermolipoma was excised and the case highlights the need for multidisciplinary care of patients with Goldenhar syndrome to monitor development.
Corneal Perforation After Topical Nepafenac Eyedrops In A Case Of Ocular Surf...Dr. Jagannath Boramani
This case report describes a 58-year-old female who developed a corneal perforation in her right eye after using Nepafenac eyedrops for 15 days to treat irritation. She had meibomian gland dysfunction and a compromised ocular surface. Topical NSAIDs like Nepafenac can cause corneal melting, especially in patients with underlying ocular surface disease. Timely treatment with antibiotics, lubricants, and a tissue adhesive helped restore the ocular surface and improve vision. Topical NSAIDs require caution and close monitoring in patients with compromised ocular surfaces due to the risk of corneal melting and perforation.
Patient Compliance To Treatment In The Management Of Glaucoma And Factors Aff...Dr. Jagannath Boramani
This document discusses a study examining patient compliance with glaucoma treatment and factors affecting compliance. The study aims to prospectively analyze at least 100 glaucoma patients to assess compliance and its determinants. So far 15 patients have been enrolled, with poor overall compliance observed. Majority of noncompliant patients had low socioeconomic status and education. The study recommends various local and general measures to improve compliance, such as educational materials, family involvement, and assistance programs.
Monocular Elevation Deficit With Pellucid Marginal Degeneration: A Case ReportDr. Jagannath Boramani
This case report discusses a 20-year-old male with right-sided ptosis, hypotropia, and poor elevation in all gazes of the right eye (monocular elevation deficit) who was also found to have pellucid marginal degeneration. Examination found severe right-sided congenital ptosis with Marcus-Gunn jaw winking phenomenon and poor Bell's phenomenon. The patient underwent right eye inferior rectus recession and Knapp's procedure with Foster augmentation to address the monocular elevation deficit. Topography was performed pre and post-operatively. The association between monocular elevation deficit and pellucid marginal degeneration has not been previously reported. Further follow up is needed to evaluate the potential association and et
Oct : Noninvasive Method To Monitor Effectivity Of Chemotherapy In Lung Car...Dr. Jagannath Boramani
Dr. Prajakta Patil(Fellow), Dr. Sarvesh Tiwari(Consultant), Dr. Gaurav Shah(Honorary Consultant), Dr. Anand Subramanyam (Head Of The Department), K. B. H. Bachooali Ophthalmic And Ent Hospital,Parel,Mumbai
Surgical Excision Of Limbal Squamous Cell Carcinoma With Cryotherapy And Mito...Dr. Jagannath Boramani
This case report describes the surgical excision of a squamous cell carcinoma located at the limbus of a patient's right eye, along with cryotherapy and topical Mitomycin-C to prevent recurrence. A 40-year old male presented with a reddish, irregular limbal mass in his right eye. The mass was excised locally under anesthesia along with cryotherapy. Topical Mitomycin-C drops were administered post-operatively to prevent recurrence, which was successful. Wide excision along with cryotherapy and Mitomycin-C is an effective treatment for limbal squamous cell carcinoma to cure the cancer and prevent recurrence.
Retinal Thickness In Macular Region Of High Myopic Eyes Using Sd-OctDr. Jagannath Boramani
The document summarizes a study that used spectral domain optical coherence tomography (SD-OCT) to measure retinal thickness in the macular region of eyes with different degrees of myopia. The study found that as the degree of myopia and axial length increased, average foveal thickness increased while inner and outer macular thickness decreased. It also found that females had thicker average foveal thickness but thinner overall macular thickness compared to males. The study provides quantitative data on changes in macular thickness correlated with myopia severity, which can help define clinical features of high myopia and develop reliable follow-up methods.
A Rare Case Of Giant Molluscum Contagiosum Lesion Presenting As Lid Tumor In ...Dr. Jagannath Boramani
A 35-year-old male presented with a large, solitary mass on his right upper eyelid that had been gradually growing over the past year. Examination revealed a 1.3 x 1.2 x 0.4 cm firm mass. The mass was excised and found to have a unusual "brain-like" appearance with multiple lobes and folds. Histopathological examination surprisingly identified the mass as a giant molluscum contagiosum lesion. This was an unusual presentation as molluscum lesions typically appear as multiple small umbilicated papules and rarely present as a solitary giant lesion in immunocompetent adults. To the authors' knowledge, this was the first reported case of such a large, solitary
A Case Of Mac Tel 2 With An Unusual Sub Macular Vitelliform LesionDr. Jagannath Boramani
This document summarizes a case study of a patient with macular telangiectasia (Mac Tel 2) who presented with an unusual submacular vitelliform lesion in one eye. On examination, the right eye showed a yellow submacular lesion on fundus exam and OCT, while the left eye showed features more consistent with Mac Tel 2 including RPE depigmentation and telangiectasia. Over three years, the lesion in the right eye remained stable while the left eye showed progression of Mac Tel 2 features. The authors discuss how this type of subretinal lesion has been observed in Mac Tel 2 and can mimic other conditions like adult-onset foveomacular dystrophy, but in this case did not
This document describes a case report of a 7-year-old girl who presented with orbital hemorrhage following minor head trauma. She had swelling, redness and diminished vision in her right eye 4 days after a fall from bed. Examination found proptosis and restricted eye movement in the right eye. Imaging with B-scan and CT scan confirmed orbital hemorrhage. She was treated conservatively with antibiotics and serratiopeptidase and showed improvement over 10 days with resolution of symptoms. The report discusses that orbital hemorrhage from minor trauma or spontaneously is rare and often resolves without intervention.
A 50-year-old male presented with decreased vision in his right eye for 4 hours. He was diagnosed with a branch retinal artery occlusion (BRAO) based on findings of an embolus blocking the filling of the artery. The patient underwent anterior chamber paracentesis, which caused the embolus to dislodge and the artery to immediately refill. Paracentesis allows for decompression of the anterior chamber to increase retinal perfusion pressure and improve the visual prognosis in BRAOs.
A 25-year-old male presented with injuries to his left eye caused by an iron rod, including a laceration to the lower eyelid involving the lacrimal canal, a tear in the conjunctiva, and a ruptured inferior rectus muscle. The patient underwent successful repair of the eyelid, lacrimal canal using a Teflon sleeve, and inferior rectus muscle during a single procedure. Post-operatively, the patient was treated with antibiotics and steroids and recovered full movement and orthophoria in the injured eye. The case report discusses that while lid lacerations and lacrimal canal injuries are commonly reported together, a case involving injury to the eyelid, lacrimal canal
Cyclothymia Test: Diagnosing, Symptoms, Treatment, and Impact | The Lifescien...The Lifesciences Magazine
The cyclothymia test is a pivotal tool in the diagnostic process. It helps clinicians assess the presence and severity of symptoms associated with cyclothymia.
Dr. Sherman Lai, MD — Guelph's Dedicated Medical ProfessionalSherman Lai Guelph
Guelph native Dr. Sherman Lai, MD, is a committed medical practitioner renowned for his thorough medical knowledge and caring patient care. Dr. Lai guarantees that every patient receives the best possible medical care and assistance that is customized to meet their specific needs. She has years of experience and is dedicated to providing individualized health solutions.
About CentiUP - Introduction and Products.pdfCentiUP
A heightened child formula, with the trio of Nano Calcium, HMO, and DHA mixed in the golden ratio, combined with NANO technology to help nourish the body deeply and comprehensively, helps children increase height, boost brain power, and improve the immune system and overall well-being.
Health Tech Market Intelligence Prelim Questions -Gokul Rangarajan
The Ultimate Guide to Setting up Market Research in Health Tech part -1
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
This lays foundation of scoping research project what are the
Before embarking on a research project, especially one aimed at scoping and defining parameters like the one described for health tech IT, several crucial considerations should be addressed. Here’s a comprehensive guide covering key aspects to ensure a well-structured and successful research initiative:
1. Define Research Objectives and Scope
Clear Objectives: Define specific goals such as understanding market needs, identifying new opportunities, assessing risks, or refining pricing strategies.
Scope Definition: Clearly outline the boundaries of the research in terms of geographical focus, target demographics (e.g., age, socio-economic status), and industry sectors (e.g., healthcare IT).
3. Review Existing Literature and Resources
Literature Review: Conduct a thorough review of existing research, market reports, and relevant literature to build foundational knowledge.
Gap Analysis: Identify gaps in existing knowledge or areas where further exploration is needed.
4. Select Research Methodology and Tools
Methodological Approach: Choose appropriate research methods such as surveys, interviews, focus groups, or data analytics.
Tools and Resources: Select tools like Google Forms for surveys, analytics platforms (e.g., SimilarWeb, Statista), and expert consultations.
5. Ethical Considerations and Compliance
Ethical Approval: Ensure compliance with ethical guidelines for research involving human subjects.
Data Privacy: Implement measures to protect participant confidentiality and adhere to data protection regulations (e.g., GDPR, HIPAA).
6. Budget and Resource Allocation
Resource Planning: Allocate resources including time, budget, and personnel required for each phase of the research.
Contingency Planning: Anticipate and plan for unforeseen challenges or adjustments to the research plan.
7. Develop Research Instruments
Survey Design: Create well-structured surveys using tools like Google Forms to gather quantitative data.
Interview and Focus Group Guides: Prepare detailed scripts and discussion points for qualitative data collection.
8. Sampling Strategy
Sampling Design: Define the sampling frame, size, and method (e.g., random sampling, stratified sampling) to ensure representation of target demographics.
Participant Recruitment: Plan recruitment strategies to reach and engage the intended participant groups effectively.
9. Data Collection and Analysis Plan
Data Collection: Implement methods for data gathering, ensuring consistency and validity.
Analysis Techniques: Decide on analytical approaches (e.g., statistical
The Ultimate Guide in Setting Up Market Research System in Health-TechGokul Rangarajan
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
"Market Research it too text-booky, I am in the market for a decade, I am living research book" this is what the founder I met on the event claimed, few of my colleagues rolled their eyes. Its true that one cannot over look the real life experience, but one cannot out beat structured gold mine of market research.
Many 0 to 1 startup founders often overlook market research, but this critical step can make or break a venture, especially in health tech.
But Why do they skip it?
Limited resources—time, money, and manpower—are common culprits.
"In fact, a survey by CB Insights found that 42% of startups fail due to no market need, which is like building a spaceship to Mars only to realise you forgot the fuel."
Sudharsan Srinivasan
Operational Partner Pitchworks VC Studio
Overconfidence in their product’s success leads founders to assume it will naturally find its market, especially in health tech where patient needs, entire system issues and regulatory requirements are as complex as trying to perform brain surgery with a butter knife. Additionally, the pressure to launch quickly and the belief in their own intuition further contribute to this oversight. Yet, thorough market research in health tech could be the key to transforming a startup's vision into a life-saving reality, instead of a medical mishap waiting to happen.
Example of Market Research working
Innovaccer, founded by Abhinav Shashank in 2014, focuses on improving healthcare delivery through data-driven insights and interoperability solutions. Before launching their platform, Innovaccer conducted extensive market research to understand the challenges faced by healthcare organizations and the potential for innovation in healthcare IT.
Identifying Pain Points: Innovaccer surveyed healthcare providers to understand their difficulties with data integration, care coordination, and patient engagement. They found widespread frustration with siloed systems and inefficient workflows.
Competitive Analysis: Analyzed competitors offering similar solutions in healthcare analytics and interoperability. Identified gaps in comprehensive data aggregation, real-time analytics, and actionable insights.
Regulatory Compliance: Ensured their platform complied with HIPAA and other healthcare data privacy regulations. This compliance was crucial to gaining trust from healthcare providers wary of data security issues.
Customer Validation: Conducted pilot programs with several healthcare organizations to validate the platform's effectiveness in improving care outcomes and operational efficiency. Gathered feedback to refine features and user interface.
2024 Media Preferences of Older Adults: Consumer Survey and Marketing Implica...Media Logic
When it comes to creating marketing strategies that target older adults, it is crucial to have insight into their media habits and preferences. Understanding how older adults consume and use media is key to creating acquisition and retention strategies. We recently conducted our seventh annual survey to gain insight into the media preferences of older adults in 2024. Here are the survey responses and marketing implications that stood out to us.
1. PURTSCHER-LIKE RETINOPATHY
Presented by- Dr Hardik Jain
Co-authors- Dr Mrunal Patil
Dr Dhiraj Balwir
( Disclosure: Author has no financial interest )
Dr Vasantrao Pawar Medical College, Nashik
2. INTRODUCTION
• Purtscher’s retinopathy or angiopathia retinae
traumatica was first described in 1910, by Otmar
Purtscher, an Austrian ophthalmologist, in a middle-
aged man who complained about bilateral vision loss
some hours after a severe head trauma.
• The ophthalmoscopic examination revealed multiple
areas of retinal whitening (Purtscher flecken) with
intraretinal hemorrhages confined to the posterior
pole in both eyes.
• Despite the gravity of vision loss, the patient recovered
his visual acuity without specific treatment.
3. • After its original description, this typical fundus
appearance was also observed in severe but non-
traumatic conditions such as acute pancreatitis,
amniotic fluid embolism, and collagen-vascular
disorders and was designated as Purtscher like
retinopathy.
• Some authors estimated an incidence of 0.24 cases per
million per year (including Purtscher and Purtscher-like
retinopathy), but it is possible that this number can be
higher due to some asymptomatic cases. However, it is
still considered a rare condition.
4. • PURPOSE:
To report Purtscher-like retinopathy which is a
rare and severe angiopathy found in
conditions such as acute pancreatitis.
• DESIGN:
A case report.
5. MATERIALS & METHODS
- A 53-year-old man with multiple cardiovascular risk
factors(diabetes, arterial hypertension,
dyslipidemia, and obesity) was admitted to the
emergency department with jaundice, nausea,
choluria, and itch present for three weeks.
Abdominal pain and fever were not present.
- Physical examination revealed jaundice with scleral
icterus.
6. • Further investigation was performed and magnetic
resonance cholangiopancreatography suggested the
presence of a Klatskin tumour (a hilar
cholangiocarcinoma) causing a principal bile duct
stenosis.
• Secondary severe pancreatitis developed and by that
time, the patient reported bilateral progressive visual
loss and floaters.
• The ophthalmologic evaluation revealed a best
corrected visual acuity (BCVA) with Snellen chart of
6/12 in the right eye (RE) and 6/24 in the left eye (LE).
7. • Biomicroscopy of the anterior segment showed scleral
icterus without rubeosis iridis.
• Mydriatic fundoscopy revealed peripapillary cotton-
wool spots, optic disc edema, and RPE hypo- and
hyperpigmentation in the middle peripheral retina of
both eyes. An intraretinal hemorrhage in the left
inferior temporal arcade was also seen. Signs of
macular edema were not present.
• Due to the patient’s severe renal compromise, it was
not possible to perform a fluorescein angiography;
instead, retinography was carried out at first
ophthalmologic evaluation.
8. RE showing peri-papilllary cotton wool spots and disc oedema
LE showing peripapillary cotton-wool spots, optic disc
edema, and an intraretinal hemorrhage in the left inferior
temporal arcade.
9. DISCUSSION
• Purtscher-like retinopathy associated with acute
pancreatitis was first described in 1975 by Inkeles and
Walsh.
• Its development is independent of the severity of
pancreatitis, and it has a wide range of manifestations
and requires a close follow-up.
• Purtscher-like retinopathy is a rare and severe
angiopathy that begins within some hours to some
days after the onset of the systemic disease and is
characterized by confluent cotton-wool spots in the
posterior pole, few intraretinal hemorrhages, and
Purtscher flecken in the acute phase.
10. • Purtscher flecken are polygonal areas of whitening in
the inner retina between the retinal arterioles and
venules with a characteristic clear zone between the
affected retina and an adjacent arteriole, extending for
an average of 50 𝜇 on either side of retinal arteries and
precapillary arterioles.
• Optic disc swelling as well as retinal edema and
pseudo-cherry spot (if macula is affected) can also be
observed in the initial phase but are less common.
• The diagnosis is clinical with sudden loss of visual
acuity associated with typical fundus appearance in the
context of a systemic illness such as acute pancreatitis
or long bone fracture.
11. CONCLUSION
• Purtscher-like retinopathy should not be neglected in
complex clinical contexts. Its unclear pathophysiology
determines an uncertain treatment strategy, but a
meticulous follow-up is compulsory in order to avoid
its severe complications.
12. REFERENCES
[1] O. Purtscher, “Noch unbekannte befunde nach schadeltrauma,” Ber Zusammenkunft Dtsch
Ophthalmol Ges Journal, vol. 36, pp. 294–301, 1910.
[2] A. Agrawal and M. A. McKibbin, “Purtscher’s and Purtscherlike retinopathies: a review,” Survey of
Ophthalmology, vol. 51, no. 2, pp. 129–136, 2006.
[3] H. A. G. deMedeiros, J.E.G. deMedeiros, L. C. Caliari, and J. F. da Silva, “Purtscher’s and Purtscher-like
retinopathies,” Revista Brasileira de Oftalmologia, vol. 68, no. 2, pp. 114–119, 2009.
[4] E. L´opez-Tiz´on, C. Reinoso-Montalvo, E. Menc´ıa-Guti´errez, and E. Guti´errez-D´ıaz, “Acute
pancreatitis presenting as sudden blindness,” Archivos de la Sociedad Espanola de Oftalmologia,
vol. 81, no. 3, pp. 161–164, 2006.
[5] A. Agrawal and M. McKibbin, “Purtscher’s retinopathy: epidemiology, clinical features and outcome,”
British Journal of Ophthalmology, vol. 91, no. 11, pp. 1456–1459, 2007.
[6] D. M. Inkeles and J. B.Walsh, “Retinal fat emboli as a sequela to acute pancreatitis,” American Journal
of Ophthalmology, vol. 80, no. 5, pp. 935–938, 1975.
[7] C. R. L. Carrera, L. M. Pierre, F. M. C. Medina, and P. T. P. Pierre-Filho, “Purtscher-like retinopathy
associated with acute pancreatitis,” Sao Paulo Medical Journal, vol. 123, no. 6, pp. 289– 291, 2005.
[8] J. P. Pina, K. Ssi-Yan-Kai, I. de Monchy, B. Charpentier, H. Offret, and M. Labetoulle, “Purtscher-like
retinopathy: case report and review of the literature,” Journal Franc¸ais d’Ophtalmologie, vol. 31,
no. 6, pp. 609–613, 2008.
[9] M. C. Kincaid, W. R. Green, D. L. Knox, and C. Mohler, “A clinicopathological case report of
retinopathy of pancreatitis,” British Journal of Ophthalmology, vol. 66, no. 4, pp. 219–226, 1982.