Defined as fracture occurring at or proximal to the surgical neck
It is the commonest fracture affecting the shoulder girdle in adults.
Proximal humeral fracture 80% of all humeral fractures.
In pts above the age of 65 years, proximal humeral fractures are the 2nd most frequent upper extremity fractures
ANATOMY -
The proximal humerus is retroverted 35 to 40 degrees relative to the epicondylar axis.
Most common is fall onto outstretched upper extremity from a standing height, in older & osteoporotic woman.
Younger pts present following high energy trauma with significant soft tissue injury.
Less common with excessive shoulder abduction, direct trauma, electric shock and seizures r seizures
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
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As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
1. Presenter: Dr Darshan K S
II year orthopaedic resident
Moderator: Dr Shekar V
Associate professor of orthopaedics
2. Defined as fracture occurring at or
proximal to surgical neck
It is the commonest fracture affecting
shoulder girdle in adults.
Proximal humeral fracture 80% of all
humeral fractures.
In pts above the age of 65 years proximal
humeral fractures are the 2nd most frequent
upper extremity fractures.
DEFINITION
6. • The ascending branch of the
anterior circumflex humeral
artery has been considered to
provide most of the blood flow
to the articular segment.
• Several studies have shown
branches from PCHA to the
posteromedial head to be
equally important.
• Arcuate artery of Liang –
supplies Humeral head.
• If the medial calcar of the
humerus is spared by the
fracture, the vessel is spared.
9. Most common is fall onto outstretched upper
extremity from a standing height, in older &
osteoporotic woman.
Younger pts present following high energy
trauma with significant soft tissue injury.
Less common with excessive shoulder
abduction, direct trauma, electric shock and
seizures r seizures.
10.
11. Four osseous segments in proximal
humerus are:
Humeral head
Lesser tuberosity
Greater tuberosity
Humeral shaft
13. Greater tuberosity is
displaced by
supraspinatus,
infraspinatus and teres
minor.
Lesser tuberosity is
displaced by
subscapularis.
Humeral shaft displaced by
pectoralis major.
Deltoid insertion
causes abduction of
proximal fragment.
14. THE PROXIMAL HUMERUS CAN
FRACTURE AS A
CONSEQUENCE OF 3 MAIN
LOADING MODES:
Compressive loading of the glenoid
onto the humeral head.
Bending forces at the surgical neck.
Tension forces of the rotator cuff at the
greater & lesser tuberosities.
15. • The majority of proximal humeral
fracture occur as isolated injuries.
• In polytrauma pts, proximal humeral
fracture frequently exhibit comminution
extending into the humeral shaft.
• In the presence of fracture dislocations,
glenoid rim and neck fracture and
avulsion fracture of the coracoid may
occur.
16. AXILLARY NERVE (58%)
SUPRASCAPULAR NERVE (48%)
Combined neurologic lesions being
frequent.
Nerve Injuries associated
VASCULAR INJURY :
-5-6% of the cases are associated
with AXILLARY ARTERY injury.
17. The association of rotator cuff
tears has been found to
increase with age.
Full-thickness tears have been
found in only 6% of proximal
humerus pts under 60 years of
age compared to 30% in those
pts above 60 years of age.
ASSOCIATED SOFT TISSUE
INJURIES
18. ATTITUDE : Pts typically present with upper
extremity held closely to chest by
contralateral hand, pain, swelling &
tenderness.
Ecchymosis may or may not be.
Neurovascular exmn. is essential. Axillary
nerve and suprascapular nerve function.
It is assessed by presence of
sensation on lateral aspect of proximal arm
overlying deltoid.(REGIMENT BADGE
SIGN)
20. Most commonly used classification is
Neer’s classification.
Useful in guiding treatment.
Based on four part anatomy of proximal
humerus.
21. It is a Refinement of Codman’s
System,incorporates the concept of
displacement and vascular isolation
of the articular segment and relates
theanatomy and biomechanical
forces resulting in the displacement
of fragments to diagnosis and
treatment
22. Criteria for displacement.
Greater than 1cm of seperation of a part or
Angulation of 45 degrees.
Osteonecrosis is most likely after displaced
four part fractures.
27. NEER LATERAL Y VIEW
OF SHOULDER.
Neer view-Scapula is imaged perpendicular
to Grashey view.
28. AXILLARY VIEWOF SHOULDER.
Axillary view-Arm in neutral rotation
and abducted as much as possible, with
the patient. supine and X-ray beam
projected from axilla
29.
30. CT of proximal humeral
fracture is helpful in
providing further
understanding of fracture
configuration.
Axial images can
confirm displacement of
the lesser and greater
tuberosity fragments in
the transverse plane.
LT
GT
31. Sagittal images help in
determining a flexion or extension
deformity of the proximal humerus
with regard to the shaft.
Coronal images give more detail
about the alignment of the humeral
head & assessment of comminution
at the level of the humeral calcar,
the integrity of the inferomedial
hinge, and extent of metaphyseal
fracture extension.
35. Fracture stability can be
assessed both
radiographically and
clinically.
Radiographically, stable
fractures exhibit impaction or
interdigitation between bone
fragments
36. • Clinically, fracture stability may be
assessed by palpating the
proximal humerus just distal to
the acromion with one hand,
while rotating the arm at the
elbow with the other. If the
proximal humerus is felt to move
as a unit with the distal segment,
the fracture is considered stable
• Gilchrist or Velpeau
type shoulder
immobilizer used.
38. • At 2 weeks passive ROM exercises
of the shoulder.
• Duration of Immobilization should be
as short as possible, and as long as
necessary.
• Resistance exercises can generally
begin at 6 weeks.
• Isometric exercises may help
maintain strength during the first 6
weeks.
39. At 3 or 4 weeks
radiographs are taken
& gentle assistive
exercises (pulley
elevation, external
rotation with a stick,
extension with a stick)
are begun.
At 6 weeks, rapid
progression to terminal
stretches and light
resistive exercises is
started
Editor's Notes
During fracture most of the times pcha gives blood supply