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BY
Dr.Nafeeya
1st yr pg
Over view
 Definition
 Risk factors
 Pathogenesis
 Signs and symptoms
 Diagnosis
 Treatment
 Prevention
 Medicolegal importance
Definition
 Acute decompression syndrome (Caisson’s disease)
is an acute neurological emergency in divers.
 Also known as divers disease, bends,staggers,aeroembolic.
 Decompression sickness is a disorder in which nitrogen dissolved in the
blood and tissues by high pressure forms bubbles .
 It occurs most frequently during deep sea diving or flying in a non
pressurized aircraft or underwater construction worker.
Risk Factors
 Alcohol excess
 Cardiac defects-patent foramen ovale,ASD
 Cold water
 Dehydration
 Exertion
 Flying after diving
 Fatigue
 Hypoxia
 Increased pressure
 Length of time spent in pressurized environment
 Medications like-antihistamines,narcotics
 Obesity
 Older age
 Rapid ascent
 Effects of high partial pressure:
 At 100 feet –increased pressure is 4 times greater than surface.
 At 120 feet-mild narcosis will appears- lose his or her self care
 At 150-200 feet-drowsy
 At 200-250-strength decreasing significantly and divers feel clumsy
to perform the work
 Beyond 250 feet-divers almost useless as a result of nitrogen narcosis
 Henry's law is one of the gas laws states that: at
a constant temperature, the amount of a given gas
that dissolves in a given type and volume of liquid is
directly proportional to the partial pressure of that gas
in equilibrium with that liquid.

P=KH C
P-PARTIAL
PRESSURE OF
THE GAS IN
THE ATOMP
PRESSURE.
C-CONC OF
DISSSOLVED
GASES
Pathogenesis
 It is a particular form of gas embolism which occurs when indiviuals
are exposed to sudden lowering of pressure .
 When air is breathed under high pressure- increased amount of gas
become dissolved in the blood
 If the divers ascents suddenly ,bubbles of nitrogen gets formed.
 It causes –
 Bends-joints and skeletal pain
 Chokes-breathing problem
 Staggers-neurological problems
Symptoms – 1-6 hours
 Dizziness
 Double vision
 Headache
 Trouble to speak
 Pain in legs-joint pain
 Itching and rashes
Serious And Life-threatening Symptoms:
affecting the brain, spinal cord, inner ear,
and/or lung
Mild Symptoms: Arthralgia, Skin
Marbling, Small Patchy
Hemorrhages, And Lymphatic
Obstruction.
Frequency & onset
Symptoms Frequency
Local Joint Pain 89%
Arm Symptoms 70%
Leg Symptoms 30%
Dizziness 5.3%
Paralysis 2.3%
Shortness Of Breath 1.6%
Extreme Fatigue 1.3%
Collapse /unconscious 0.5%
Time to
onset
% of cases
Within 1
hour
42%
Within 3
hours
60%
Within 8
hours
83%
Within 24
hours
98%
Within 48
hours
100%
Diagnosis
1)X-ray and CT scan of whole body
2)Suspected venous embolism:
a)Abdomen opened first
b)Opening of the chest
c)PM demonstration of venous
embolism
d)Source of air - Air in SVC(stab wounds
of neck)
e)Composition of air - >95% nitrogen-
nitrogen narcosis
Treatment
 100% Hyperbaric oxygen
therapy followed by
 Recompression in a
hyperbaric chamber.
 Platelet inhibitors
 Anti-inflammatory drugs are
also useful.
Prevention
 To prevent the excess formation of bubbles leading to decompression
sickness, divers limit their ascent rate
 Dive and rise slowly in the water, and don't stay at your deepest depth
longer than recommended.
 Do not fly within 24 hours after diving.
 Don't drink alcohol before diving.
 Avoid hot tubs or hot baths after diving.
 Make sure you are well hydrated, well rested and prepared before you
scuba dive.
Region Autopsy findings
External examination cyanosis, cherry red coloration,marbling ,facial
edema,froth in mouth and nose,mottled pallor of
tongue ,abrasions ,contusions ..
Head and neck #,gas bubbles in cerebral arteries,vessels,
SDH,SAH,focal hge,cerebral edema
Eyes and ears Rupture of tympanic membrane,gas in retinal
vessels
Chest ,tracheobronchial tree,and lungs Foam,aspirated vomit,pneumothorax,pulmonary
edema,petechial hemorrhage,nitrogen bubbles in
pericapillary pulmonary arteries,fat emboli.
Blood from heart Air embolism,alcohol intoxication,CO .
Heart Air embolism ,IHD
Other organs Fatty change liver,infarction in many organs
Spinal cord Nitrogen bubbles in spinal arteries
Bones and joints Dysbaric osteonecrosis
PM DEMONSTRATION
1) Air in right ventricle
Sternum removed
Vessels clamped
Pericardium opened
Beaded appearance
Coronaries incised
2)Minus plunger
3)Pyrogallol test
AIR EMBOLISM
Pyrogallol Test
 RAPID AUTOPSY TEST
 Principle
1)putrifactive gases will not contain any o2
2)Alkaline solution turns purple
 Procedure
1)4ml freshly prepared 2%pyrogallol solution-2
syringes
2)1st syringe-add 4 drops of 0.5M NaOH – RV –
aspirate – seal -
shake – turns purple
3)2nd syringe – as control - turn brown in all cases
MEDICOLEGAL IMPORTANCE:
 Underwater Crime
 Scuba Deaths
 Underwater Disasters
 Underwater photograpny
 Recreational Diving Fatalities
 Forensic Biology
 Education Archives
 Cave Divers Unlock Mysteries
 Suicidal Inhalation
References
 Anil agarwal text book of forensic medicine
 Knights –forensic pathology
 Narayana reddy textbook of forensic medicine
 Dikishit textbook of forensic medicine
 Gautam Biswas-Review of forensic medicine and toxicology
 International Journal of Advanced Research (2016), Volume 4,
Issue 2, 25-30/6https://
 Journals.sagepub.com/doi/10.1177/0025817217734481
 July 2013 Journal of Forensic Sciences 58(5)
DOI: 10.1111/15564029.12239 Source PubMed



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caissons disease

  • 2. Over view  Definition  Risk factors  Pathogenesis  Signs and symptoms  Diagnosis  Treatment  Prevention  Medicolegal importance
  • 3. Definition  Acute decompression syndrome (Caisson’s disease) is an acute neurological emergency in divers.  Also known as divers disease, bends,staggers,aeroembolic.  Decompression sickness is a disorder in which nitrogen dissolved in the blood and tissues by high pressure forms bubbles .  It occurs most frequently during deep sea diving or flying in a non pressurized aircraft or underwater construction worker.
  • 4.
  • 5. Risk Factors  Alcohol excess  Cardiac defects-patent foramen ovale,ASD  Cold water  Dehydration  Exertion  Flying after diving  Fatigue  Hypoxia  Increased pressure  Length of time spent in pressurized environment  Medications like-antihistamines,narcotics  Obesity  Older age  Rapid ascent
  • 6.  Effects of high partial pressure:  At 100 feet –increased pressure is 4 times greater than surface.  At 120 feet-mild narcosis will appears- lose his or her self care  At 150-200 feet-drowsy  At 200-250-strength decreasing significantly and divers feel clumsy to perform the work  Beyond 250 feet-divers almost useless as a result of nitrogen narcosis
  • 7.  Henry's law is one of the gas laws states that: at a constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid.  P=KH C P-PARTIAL PRESSURE OF THE GAS IN THE ATOMP PRESSURE. C-CONC OF DISSSOLVED GASES
  • 8. Pathogenesis  It is a particular form of gas embolism which occurs when indiviuals are exposed to sudden lowering of pressure .  When air is breathed under high pressure- increased amount of gas become dissolved in the blood  If the divers ascents suddenly ,bubbles of nitrogen gets formed.  It causes –  Bends-joints and skeletal pain  Chokes-breathing problem  Staggers-neurological problems
  • 9. Symptoms – 1-6 hours  Dizziness  Double vision  Headache  Trouble to speak  Pain in legs-joint pain  Itching and rashes Serious And Life-threatening Symptoms: affecting the brain, spinal cord, inner ear, and/or lung Mild Symptoms: Arthralgia, Skin Marbling, Small Patchy Hemorrhages, And Lymphatic Obstruction.
  • 10. Frequency & onset Symptoms Frequency Local Joint Pain 89% Arm Symptoms 70% Leg Symptoms 30% Dizziness 5.3% Paralysis 2.3% Shortness Of Breath 1.6% Extreme Fatigue 1.3% Collapse /unconscious 0.5% Time to onset % of cases Within 1 hour 42% Within 3 hours 60% Within 8 hours 83% Within 24 hours 98% Within 48 hours 100%
  • 11. Diagnosis 1)X-ray and CT scan of whole body 2)Suspected venous embolism: a)Abdomen opened first b)Opening of the chest c)PM demonstration of venous embolism d)Source of air - Air in SVC(stab wounds of neck) e)Composition of air - >95% nitrogen- nitrogen narcosis
  • 12.
  • 13.
  • 14. Treatment  100% Hyperbaric oxygen therapy followed by  Recompression in a hyperbaric chamber.  Platelet inhibitors  Anti-inflammatory drugs are also useful.
  • 15. Prevention  To prevent the excess formation of bubbles leading to decompression sickness, divers limit their ascent rate  Dive and rise slowly in the water, and don't stay at your deepest depth longer than recommended.  Do not fly within 24 hours after diving.  Don't drink alcohol before diving.  Avoid hot tubs or hot baths after diving.  Make sure you are well hydrated, well rested and prepared before you scuba dive.
  • 16. Region Autopsy findings External examination cyanosis, cherry red coloration,marbling ,facial edema,froth in mouth and nose,mottled pallor of tongue ,abrasions ,contusions .. Head and neck #,gas bubbles in cerebral arteries,vessels, SDH,SAH,focal hge,cerebral edema Eyes and ears Rupture of tympanic membrane,gas in retinal vessels Chest ,tracheobronchial tree,and lungs Foam,aspirated vomit,pneumothorax,pulmonary edema,petechial hemorrhage,nitrogen bubbles in pericapillary pulmonary arteries,fat emboli. Blood from heart Air embolism,alcohol intoxication,CO . Heart Air embolism ,IHD Other organs Fatty change liver,infarction in many organs Spinal cord Nitrogen bubbles in spinal arteries Bones and joints Dysbaric osteonecrosis
  • 17.
  • 18. PM DEMONSTRATION 1) Air in right ventricle Sternum removed Vessels clamped Pericardium opened Beaded appearance Coronaries incised 2)Minus plunger 3)Pyrogallol test AIR EMBOLISM
  • 19. Pyrogallol Test  RAPID AUTOPSY TEST  Principle 1)putrifactive gases will not contain any o2 2)Alkaline solution turns purple  Procedure 1)4ml freshly prepared 2%pyrogallol solution-2 syringes 2)1st syringe-add 4 drops of 0.5M NaOH – RV – aspirate – seal - shake – turns purple 3)2nd syringe – as control - turn brown in all cases
  • 20. MEDICOLEGAL IMPORTANCE:  Underwater Crime  Scuba Deaths  Underwater Disasters  Underwater photograpny  Recreational Diving Fatalities  Forensic Biology  Education Archives  Cave Divers Unlock Mysteries  Suicidal Inhalation
  • 21. References  Anil agarwal text book of forensic medicine  Knights –forensic pathology  Narayana reddy textbook of forensic medicine  Dikishit textbook of forensic medicine  Gautam Biswas-Review of forensic medicine and toxicology  International Journal of Advanced Research (2016), Volume 4, Issue 2, 25-30/6https://  Journals.sagepub.com/doi/10.1177/0025817217734481  July 2013 Journal of Forensic Sciences 58(5) DOI: 10.1111/15564029.12239 Source PubMed  