1) King Charles V abdicated parts of his empire to his son Philip II in 1554-1556, including Spain and the Netherlands but not the German Empire, which passed to Ferdinand.
2) Philip II became king of Portugal in 1580 after the death of King Sebastian I left the throne disputed.
3) Philip II ruled over a vast global Spanish Empire but faced ongoing conflicts including wars against Protestants, Muslims, England, and France throughout his reign from 1556 to 1598.