The Ottoman Empire ruled a large portion of the Middle East and Eastern Europe for over 600 years, beginning in 1299. In 1453, Mehmet II captured Constantinople, establishing Istanbul as the new capital and greatly expanding Ottoman power. However, over time the empire began to decline due to factors such as weak sultans, corruption, and loss of territory to European powers. By the late 1600s the once powerful empire had ceased expanding and faced economic challenges, leading to its eventual dissolution in 1923 with the founding of the modern Republic of Turkey.