Colophony, also known as rosin, is obtained from the distillation residue of pine resin from species of pine trees. It is produced in North America, Northern Europe, Pakistan, and India. Colophony is a pale yellow to brown solid that is insoluble in water but soluble in alcohol, chloroform, ether, and acetic acid. Its major constituent is abietic acid, it has a melting point between 75-85°C, and can be identified through chemical tests involving acetic anhydride and sulfuric acid or copper acetate. Colophony has pharmaceutical uses as a diuretic and in ointments and plasters, and industrial uses in varnishes, soaps,

1. PRESENTATIONONCOLOPHONY
BIPLOB DEY
B.Pharm (2015-19)
Dev Bhoomi Institute of Pharmacy & Research
Dehradun,Uttarakhand
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2.  Rosin
 Rosina
 Colophonium
 Amber-resin
 Pine-resin
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3. Biological Source
• It is mainly obtained from the species of pinus
belonging to the family Pinaceae
• Plant crude oleo resin
Distillation
Oil of
turpentine
Residue
(COLOPHONY)
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4. Geographical Source
Its prepared in North America,
Northen Europe, Pakistan and India.
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5. •Colour- Pale yellow to yellowish brown
•Odour- Faint & characterstic
•Shape and size - It occurs in the form of angular,
translucent, masses of various sizes .
•Taste- characterstic
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6. Insoluble in water
BUT
Soluble in alcohol, chloroform,
ether ,acetic acid and many
volatile and fixed oil
Solubility
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7.  Melting point- 750C-850C
 Acid value- 130 to 180
 Saponification value- 188 to 192
 Ash value- Not more than 0.125%
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8. Chemical constituent
 Major constituent of the colophony is
Abietic acid (Resin acid) about 90%
or vary on the basis of source and
storage condition.
 The colophony also contain 0.5 %
volatile oil,pimeric acid and Sapinic
acid.
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9. Test 1:- 1 gm of colophony
Dissolve in 10 ml of acetic anhydride by gentle heat
Add a drop of conc. Sulphuric acid
Bright red color changing to violet
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10. Test 2:-
Dissolve colophony in light petroleum ether
Make double with dilute solution copper acetate
Petroleum layer takes emerald green color
(Due to copper salt of abietic acid)
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11. Uses
1. Pharmaceutical Uses-
 As a diuretic
 It is also used in the preparation of some types
of Ointments.
 It is ingredient of certain plaster masses
2. Industrial Uses-
 Preparation of varnishes
 Soaps , Printing inks.
 Soldering compound and as a pressure
sensitive adhesive.
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12. Storage
• Well closed and well filled container .
• Away from light and Cool place.
• In the powder form it gets oxidized quickly and losses its solubility
in light petroleum.
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13. Adulterants:-
• Colophony is adulterated with black resin
or apic resin.
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14. THANK YOU
FOR LISTENING
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15. QUESTION• m
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