Perthes disease is a rare childhood condition that affects the hip. It occurs when the blood supply to the rounded head of the femur (thighbone) is temporarily disrupted. Without an adequate blood supply, the bone cells die, a process called avascular necrosis.
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Avascular necrosis (AVN) of the femoral head is a pathologic process that results from interruption of blood supply to the bone. AVN of the hip is poorly understood, but this process is the final common pathway of traumatic or nontraumatic factors that compromise the already precarious circulation of the femoral head. Femoral head ischemia results in the death of marrow and osteocytes and usually results in the collapse of the necrotic segment
Tendoachilles rupture and its managementRohan Vakta
Achilles tendon is the strongest tendon of body. There are many causes of its rupture. It can be acute or chronic rupture. Management of chronic rupture by semitendinosus tendon is mentioned here.
Avascular necrosis (AVN) of the femoral head is a pathologic process that results from interruption of blood supply to the bone. AVN of the hip is poorly understood, but this process is the final common pathway of traumatic or nontraumatic factors that compromise the already precarious circulation of the femoral head. Femoral head ischemia results in the death of marrow and osteocytes and usually results in the collapse of the necrotic segment
LCPD or Perthes disease - idiopathic avascular necrosis of femoral head, characterized mainly in child age 4-7 years - with a feature of limping and pain in the hip or groin
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2. Perthes Disease
• Also known as-
o Legg-Calve-Perthes disease.
o Calve Perthes disease.
o Avascular necrosis.
o Coxa plana
o Pseudocoxalgia
• It is an osteochondritis of the epiphysis of the femoral head.
• In this disease the femoral head become partly or wholly avascular and
deformed.
3. Epidemiology
• Legg-Calve-Perthes disease is the
most common hip disease that
afflicts school-age children.
• The disorder was described by three
independent authors in 1910.
• Arthur Legg
• Jacques Calve
• Georg Perthes
• They might have surprised to see(if
alive)how much and how little have
changed in 100 years
Legg Calve
4. What is Perthes Disease ?
• Perthes disease is a childhood disorder which affects
the head of the femur.
• It is a vascular problem affect 1 in 10000 child (4 in
10000 in India)
• In Perthes disease the blood supply to the growth
plate of the bone at the end of the femur becomes
inadequate.
• As a result the bone softens and breaks down due to
avascular necrosis.
5. Incidence
• Legg-Calve-Perthes disease generally occurs in children between 4 to 8
years of age.
• With males being affected about four to five times more frequently than
females.
• It is a unilateral in 90 percent of patients, while the other 10 percent of
patients have bilateral hip.
• Rates as low as 3.8 per 100,000 have been reported in Korea, and very
similar rates of 4.4 per 100,000 have been identified in Southern India.
7. Vascular Phenomena
• Up to the age of 4 months, the femoral head is supplied by -
1) Metaphyseal vessels which penetrate the growth disc
2) Lateral epiphyseal vessels running in the retinacula and
3) Scanty vessels in the ligamentum teres
• The metaphyseal blood supply -
1) Gradually declines until, by the age of 4 years.
2) It has virtually disappeared; by the age of 7 years.
3) However, the vessels in the ligamentum teres have developed.
• Between 4 and 7 years of age the femoral head may depend for its blood
supply and venous drainage almost entirely on the Lateral Epiphyseal
Vessels whose situation in the retinacula makes them susceptible to
stretching and pressure from an effusion.
8. Pathophysiology
• Another factor which needs to be taken into account Is that the vascular
sinusoids which nourish the marrow and bone cells ,unlike arterial
capillaries, have no adventitial layer and their patency is determined by the
volume and pressure of the surrounding marrow tissue ,which itself is
encased in unyielding bone.
• The system functions essentially as a closed compartment within which one
element can expand the presser(marrow presser)
9. Bones Vulnerable to Ischemia
• Sites which are vulnerable to ischemic necrosis are-
1. Femoral Head,
2. Femoral Condyles
3. Head of the Humerus
4. Capitulum
5. Proximal Part of Scaphoid
6. Talus.
10. Pathology
• Once a critical portion of blood flow to the femoral head has been
compromised.
• The femoral head will begin to take on a pathologic shape leading to -
• Flatening
• Fragmentation
• Collapse
Flatening Fragmentation Collapse Collapse
11. Etiology
• It is not clear why this blood vessel
problem occurs in the femoral head.
• Factors which has been implicated are -
1) Heredity
2) Trauma
3) Endocrine
4) Inflammatory
5) Nutritional
6) Altered circulatory hemodynamic
Bilateral -15% Cases
Unilateral - 80% Cases
12. Clinical Features
• It occur commonly in boys of age group from 5 to 10 years.
• The signs and symptoms of -Perthes disease can be rather slow and may not be
immediately recognized by parents or by treating doctor.
• They may simply perceive a slightly abnormal gait
• Since there is no complaint of pain, little attention on may be paid to it.
• If hip/knee/groin pain is present, it may worsen towards the end of a strenuous day
and is often relieved by rest.
• Gait pattern disturbed-limp
• Often present with a Trendelenburg gait, ( abductor lurch.)
• ROM diminished-- loss of abduction and internal rotation.
13. Clinical Feature
• Symptoms -
1) Hip, knee or groin pain,
exacerbated by hip/leg
movement, especially internal hip
rotation .
2) Hip pain radiating to knee.
3) There may limping and stiffness.
4) Reduced range of motion –
i. Abduction and
ii. Internal rotation
iii. Patient presents with a limp.
5) Pain is usually mild.
• Signs -
1) Wasting of the muscles in the
upper thigh.
2) Shortening of the leg
3) Stiffness of the Hip
4) Difficulty in Squatting
PAIN IN KNEE- SHOULD BE CONSIDERED AS HIP IN CHILDREN UNLESS OTHERWISE PROVED
14. Stages of Perthes Disease
• Necrosis: Initial period of ischemia/loss of blood supply to femoral head.
• Fragmentation: Re-absorption of bone with femoral head collapse.
• Re-ossification: New bone re-grows to reshape the femoral head.
• Remodeling: Femoral head reshapes itself into normal spherical shape.
15. Diagnosis
• X-rays of the hip
• Finding
1) Femoral head broken or damaged.
2) Collapse and sclerosis of epiphysis
of femoral head.
3) Hip joint space increase.
4) Flattened femoral head(Typical).
• Bone Scan
• Done for confirmation of Perthes
Disease , when X-ray picture is normal.
• MRI
• Use to asses the extent of damage.
16. Differential Diagnosis
• The irritable hip of early Perthes’ disease must be differentiated from
other causes of irritability -
1) Morquio’s disease
2) Cretinism
3) Multiple epiphyseal dysplasia
4) Sickle-cell disease
5) Gaucher’s disease (may resemble Perthes’ disease radiologically, especially if they
are bilateral; however, in bilateral Perthes’ disease the two sides are likely to be
at different stages. )
• In Old Perthes deformities’ in adults, in the 10 per cent of cases with
bilateral involvement, may resemble those of certain bone dysplasias,
especially multiple epiphyseal dysplasia.
17. What is the Treatment for Perthes Disease ?
• The overall goal of treatment is -
1) To reduce hip irritability and pain
2) Restore and maintain hip mobility
3) To prevent the femoral head from extruding or collapsing
4) To regain a spherical shape of the femoral head
• It can be achieved by-
• Conservative (or)
• Operative Method
18. Conservative Treatment
• Observation
• Physical
• Therapy/Traction to improve range of motion
• Splints and abduction. Cast in internal rotation
Ptrei Cast
19. Treatment Related to Age
• Children under 6 years
• No specific form of treatment has much influence on the outcome. Symptomatic
treatment, including activity modification.
• Bone age at or below 6 years
• Lateral pillar group A and B (or Catterall stage I and II) – symptomatic treatment.
• Lateral pillar group C (or Catterall stage III and IV)– abduction brace.
• Bone age over 6 years
• Lateral pillar group A and B (Catterall stage I and II) – abduction brace or
osteotomy.
• Lateral pillar group C (Catterall stage III and IV) – outcome probably unaffected by
treatment, but some would operate.
• Children 9 years and older
• Operative containment is the treatment of choice.
23. Prognostic Feature
• The outlook for children with Perthes’ disease, as a group, is well
summarized by Herring (1994):
• A small % of patients have a very difficult course, with recurrent loss of motion,
pain, and an eventual poor outcome.
• However, most children have moderate problems in the active phase of the
disease and then improve steadily, leading to satisfactory outcome.’