The document discusses several key properties of electromagnetic waves including polarization, interference, diffraction, dispersion, reflection, and refraction. It provides definitions and examples of each property. Specifically, it defines polarization as parallel or non-parallel vibration of light waves, and describes how polarization filters work. It also discusses the conditions needed for interference and defines constructive and destructive interference. Diffraction is defined as the bending of waves around obstacles. Dispersion is the separation of visible light into different colors.
Lacrimal function tests evaluate the tear drainage system and tear production. The tests described include sac syringing to check for obstructions, Jones dye tests 1 and 2 to locate partial blockages, and Schirmer tests 1 and 2 and tear film breakup time to assess tear production and dry eye. These tests are used to diagnose conditions such as epiphora (excess tearing) or dry eye that could be caused by issues with the lacrimal gland or lacrimal drainage system.
- A schematic eye is a mathematical model that represents the basic optical features of the real eye by using spherical surfaces and constant refractive indices.
- The first schematic eyes were developed in the 17th-19th centuries by scientists like Huygens, Smith, Le Grand, and Listing. Gullstrand further improved the model with four lens surfaces and refractive index gradients.
- Modern schematic eyes like Gullstrand's simplified model with three surfaces are commonly used for calculations involving refraction, image size and location, and the effects of refractive errors. While approximations, schematic eyes provide a framework for understanding ocular optics.
1. Light is an electromagnetic radiation that exhibits both wave-like and particle-like properties. As a wave, it can undergo phenomena such as interference, diffraction, and polarization. As a particle, it demonstrates properties like the photoelectric effect.
2. Light interacts with matter in several ways including absorption, transmission, reflection, and scattering. Scattering of light in the eye causes issues like glare and reduces retinal image contrast.
3. Lasers utilize the particle and wave properties of light to perform functions like photocoagulation, photoablation, and photodisruption in ophthalmic procedures and treatments. Precise delivery of laser energy allows for applications in retinal photocoagulation and refractive surgery.
Laser is an acronym for Light Amplification by Stimulated Emission of Radiation.
Ophthalmology is the first medical specialty to incorporate the use of lasers. Since its first use, lasers have been modified and adapted to different uses
The document discusses parameters for analyzing corneal topography scans from the Pentacam. It describes various indices and maps generated by the Pentacam that are used to evaluate corneal shape, thickness, and biomechanical properties. Key parameters include the ISV, IVA, IHA, and IHD indices, BAD-D values, PPI and ART values, and the 13-point algorithm classification. Together these provide a comprehensive overview of corneal shape and help distinguish normal corneas from those with conditions like keratoconus.
Aberrations are defects in an optical system that prevent light from being brought to a single focus. There are two main types: chromatic aberration, caused by the wavelength-dependent refractive index of materials, and monochromatic aberration, caused by flaws in the lens design. Five primary monochromatic aberrations were described by Seidel: spherical aberration, coma, astigmatism, field curvature, and distortion. Spherical aberration occurs when peripheral rays converge at a different point than paraxial rays, degrading image focus. Coma and astigmatism affect image sharpness for off-axis points. Field curvature results in a curved image plane rather than a flat one. Distortion al
Optical coherence tomography (OCT) is a non-invasive imaging technique that uses light to obtain high-resolution cross-sectional images of the retina and anterior segment. OCT of the retina provides images similar to a vertical biopsy under a microscope, with micron-level resolution. Applications of OCT include ophthalmology, dermatology, cardiology, endoscopy, and guided surgery. OCT measures reflected light using interferometry, similar to ultrasound but using light instead of sound. It has much higher resolution than ultrasound. OCT is useful for detailed imaging of the retina and anterior segment, while ultrasound can image deeper structures due to its ability to penetrate tissue.
Keratometry is a technique to measure the curvature of the cornea using a keratometer. A keratometer projects illuminated circles called mires onto the cornea which form reflected images. By measuring the size of the reflected images, the radius of curvature of the cornea can be calculated in two principal meridians. Keratometry is used to measure corneal astigmatism and monitor the shape of the cornea for conditions like keratoconus. Automated keratometers have replaced manual keratometers and can measure corneal curvature more quickly and accurately.
Lacrimal function tests evaluate the tear drainage system and tear production. The tests described include sac syringing to check for obstructions, Jones dye tests 1 and 2 to locate partial blockages, and Schirmer tests 1 and 2 and tear film breakup time to assess tear production and dry eye. These tests are used to diagnose conditions such as epiphora (excess tearing) or dry eye that could be caused by issues with the lacrimal gland or lacrimal drainage system.
- A schematic eye is a mathematical model that represents the basic optical features of the real eye by using spherical surfaces and constant refractive indices.
- The first schematic eyes were developed in the 17th-19th centuries by scientists like Huygens, Smith, Le Grand, and Listing. Gullstrand further improved the model with four lens surfaces and refractive index gradients.
- Modern schematic eyes like Gullstrand's simplified model with three surfaces are commonly used for calculations involving refraction, image size and location, and the effects of refractive errors. While approximations, schematic eyes provide a framework for understanding ocular optics.
1. Light is an electromagnetic radiation that exhibits both wave-like and particle-like properties. As a wave, it can undergo phenomena such as interference, diffraction, and polarization. As a particle, it demonstrates properties like the photoelectric effect.
2. Light interacts with matter in several ways including absorption, transmission, reflection, and scattering. Scattering of light in the eye causes issues like glare and reduces retinal image contrast.
3. Lasers utilize the particle and wave properties of light to perform functions like photocoagulation, photoablation, and photodisruption in ophthalmic procedures and treatments. Precise delivery of laser energy allows for applications in retinal photocoagulation and refractive surgery.
Laser is an acronym for Light Amplification by Stimulated Emission of Radiation.
Ophthalmology is the first medical specialty to incorporate the use of lasers. Since its first use, lasers have been modified and adapted to different uses
The document discusses parameters for analyzing corneal topography scans from the Pentacam. It describes various indices and maps generated by the Pentacam that are used to evaluate corneal shape, thickness, and biomechanical properties. Key parameters include the ISV, IVA, IHA, and IHD indices, BAD-D values, PPI and ART values, and the 13-point algorithm classification. Together these provide a comprehensive overview of corneal shape and help distinguish normal corneas from those with conditions like keratoconus.
Aberrations are defects in an optical system that prevent light from being brought to a single focus. There are two main types: chromatic aberration, caused by the wavelength-dependent refractive index of materials, and monochromatic aberration, caused by flaws in the lens design. Five primary monochromatic aberrations were described by Seidel: spherical aberration, coma, astigmatism, field curvature, and distortion. Spherical aberration occurs when peripheral rays converge at a different point than paraxial rays, degrading image focus. Coma and astigmatism affect image sharpness for off-axis points. Field curvature results in a curved image plane rather than a flat one. Distortion al
Optical coherence tomography (OCT) is a non-invasive imaging technique that uses light to obtain high-resolution cross-sectional images of the retina and anterior segment. OCT of the retina provides images similar to a vertical biopsy under a microscope, with micron-level resolution. Applications of OCT include ophthalmology, dermatology, cardiology, endoscopy, and guided surgery. OCT measures reflected light using interferometry, similar to ultrasound but using light instead of sound. It has much higher resolution than ultrasound. OCT is useful for detailed imaging of the retina and anterior segment, while ultrasound can image deeper structures due to its ability to penetrate tissue.
Keratometry is a technique to measure the curvature of the cornea using a keratometer. A keratometer projects illuminated circles called mires onto the cornea which form reflected images. By measuring the size of the reflected images, the radius of curvature of the cornea can be calculated in two principal meridians. Keratometry is used to measure corneal astigmatism and monitor the shape of the cornea for conditions like keratoconus. Automated keratometers have replaced manual keratometers and can measure corneal curvature more quickly and accurately.
There are four axes of the human eye: the optical axis, visual axis, fixation axis, and pupillary axis. There are also three angles of the eye: angle kappa is formed between the pupillary axis and visual axis, angle alpha is formed between the optical axis and visual axis, and angle gamma is formed between the optical axis and fixation axis.
Corneal degeneration refers to conditions where the normal cells of the cornea undergo degenerative changes due to age or pathology. There are several types of corneal degenerations that can be classified based on location (axial or peripheral) and etiology (age-related or pathological). Common age-related peripheral degenerations seen in elderly individuals include arcus senilis, Vogt's white limbal girdle, and Hassall-Henle bodies. Arcus senilis appears as a grey or white ring around the peripheral cornea and is non-pathological. Vogt's white limbal girdle is similar but can occur in younger people and may be associated with hypercholesterolemia. Hassall-
This document describes various methods of illumination used with a slit lamp to examine different parts of the eye. Diffuse illumination allows for a general survey of the eye while optic section, parallelepiped, and retroillumination techniques are used to view specific structures like the cornea, lens, and vitreous in more detail. Different angles of illumination like tangential, conical beam, and oscillatory help observe surface textures, cells in the aqueous humor, and lens opacities. Precise illumination techniques are crucial for comprehensive eye exams.
Fluorescein angiography involves injecting a fluorescent dye called sodium fluorescein intravenously and using specialized cameras with excitation and barrier filters to take photos of the retina as the dye circulates. It has revolutionized the diagnosis of retinal vascular diseases since the 1960s by allowing visualization of blood flow and detection of leaks. Care must be taken with patients on beta-blockers or with iodine allergies, as rare severe reactions including anaphylaxis can occur.
1. Accommodation is the mechanism by which the eye changes its refractive power to focus on objects at different distances. It occurs when the ciliary muscle contracts, allowing the lens to become more curved and powerful.
2. Accommodation has two components - physical accommodation involving the actual deformation of the lens, and physiological accommodation involving the contractile power of the ciliary muscle. Terminologies like far point, near point, and amplitude of accommodation are used to describe accommodation.
3. Accommodation is assessed using tests like RAF rule, pushup test, and dynamic retinoscopy to measure the near point, amplitude, and accommodative response respectively. Assessment of dynamic accommodation involves testing accommodative facility using
what is Duochrome Test, Why do we take Red and Green color only,
What is the Principal of Duochrome Test, Why Hyperopic Pt sees green better than red and vice versa
Gonioscopy allows visualization of the anterior chamber angle structures. It was coined by Alexios Trantas in 1975 from the Greek words "gonia" meaning angle and "skopein" meaning to view. There are two main types - direct gonioscopy using a Koeppe lens which provides a panoramic view but no magnification, and indirect gonioscopy using a Goldmann lens which provides a segmented view through a mirror with excellent optics and the ability to perform indentation. Gonioscopy is used diagnostically to classify glaucoma and assess angle anatomy and closure risk, and therapeutically for procedures like laser trabeculoplasty.
The retina is the innermost layer of the eye that converts light into neural signals. It contains several layers of tissue and cell types that carry out this visual transduction process. The outermost layer contains pigmented cells, followed by photoreceptor cells (rods and cones), bipolar and ganglion cells that transmit signals to the brain. Within the retina, the macula provides high-acuity central vision and the optic disc is where retinal ganglion cell axons exit as the optic nerve. The retina receives its blood supply from the central retinal artery and precise vascular architecture is important for normal visual function.
The tear film has three layers:
1. A mucin layer secreted by goblet cells that forms a hydrophilic barrier on the cornea.
2. An aqueous layer secreted mainly by the lacrimal gland, containing proteins, electrolytes, and other components.
3. An outer lipid layer secreted by meibomian glands that prevents evaporation and maintains tear film stability.
The tear film is regulated by hormonal and neural pathways and provides nutrients to the cornea, removes waste, lubricates the eye, and protects against infection through its biochemical composition.
The document discusses the optical aberrations present in the normal human eye. It describes mechanisms that decrease aberrations, including the iris cutting peripheral rays, the high refractive index of the lens core, and retinal sensitivity patterns. The primary aberrations discussed are diffraction of light forming an airy disc pattern, spherical aberration bringing peripheral rays to different focal points than para-axial rays, coma aberration forming a comma shape, and chromatic aberration focusing different wavelengths to different depths. Decentering of the lens and oblique aberrations from peripheral vision are also mentioned.
An epiretinal membrane is an avascular fibrocellular membrane that grows on the inner surface of the retina, causing macular dysfunction. It consists of various cell types and collagen. Symptoms include blurry vision and metamorphopsia. Observation is usually sufficient for mild cases, but surgery is recommended for significant vision loss or distortion. Peeling the membrane improves vision in most cases, though cataracts are a common complication. Prognosis is better when pre-op vision is good and the duration of symptoms is short.
This document provides an overview of lasers used in ophthalmology. It discusses the history and physics of lasers, describing key laser characteristics and components. Different types of lasers are outlined, along with factors that determine laser tissue interaction and complications. Applications of lasers in anterior and posterior segment eye diseases are summarized. Delivery systems including slit lamps and scanning laser ophthalmoscopes are also covered, along with safety considerations.
The document summarizes key optical structures and properties of the eye. It describes the cornea as having a convex shape that refracts light and protects the eye. It then discusses the aqueous humor, crystalline lens, and vitreous humor, noting their roles in refraction due to differences in density. Schematic and reduced eye models are presented, including cardinal points and refractive indices. Common refractive errors like myopia and hyperopia are also outlined.
Keratometry is a technique used to measure the radius of curvature of the anterior corneal surface using an instrument called a keratometer. The keratometer utilizes the reflective properties of the cornea to measure the size of an image formed by reflection of an object of known size and position, allowing the radius of curvature to be calculated. Commonly, keratometers either use a fixed doubling system with variable mires or a variable doubling system with fixed mires. Measurements from keratometry are used to fit contact lenses and monitor corneal changes from contact lens wear.
Astigmatic lens used in ophthalmology and eyeRACHANA KAFLE
different types and classifications of astigmatic lens used
availability of astigmatic lens
uses of astigmatic lens
advantages and disadvantages of astigmatic lens
The document describes the components and uses of a trial box, which is a set of lenses, frames, and accessories used to test vision. It contains trial frames that hold spherical, cylindrical, and prismatic lenses in various diopters for refraction testing. Accessories include occluders, filters, charts, and tools like Maddox rods and cross cylinders. The trial box is used for objective and subjective refraction, diagnosing conditions like squint, and assessing binocular vision.
A lens clock is a mechanical device used to measure the curvature and optical power of a lens surface. It has three legs - two outer fixed legs and one inner movable leg. The difference in height between the inner and outer legs corresponds to the curvature of the lens surface. The lens clock converts this curvature measurement into a diopter value, assuming the lens material has a refractive index of 1.523. Rotating the lens clock allows measuring any cylindrical component of the lens. Adding the power readings from the front and back surfaces provides an estimate of the total lens power.
This document discusses various materials used in ophthalmic lenses. It describes the optical, mechanical, electrical, chemical and thermal properties of different lens materials like glass and plastics. Specifically, it provides details on the properties of different types of glass lenses including crown glass, flint glass, barium crown glass, and high index glass. It also discusses plastic lenses and highlights the use of high index lenses for higher prescriptions to reduce lens thickness.
The document discusses various theories of light, including Newton's corpuscular theory, Huygens' wave theory, Maxwell's electromagnetic theory, and Einstein's quantum theory. It also discusses key properties of light such as reflection, refraction, interference, polarization, diffraction, and dispersion. Optical science refers to the study of light and its interactions with matter. Light can be defined as energy that the human eye is sensitive to and exists in the electromagnetic spectrum between X-rays and microwaves.
These lectures has prepared for postgraduate student (Ophthalmology) according to the curriculum of Bangladesh College of Physician and Surgeons (BCPS) and Bangabondhu Sheikh Mujib Medical University (BSMMU) Bangladesh
There are four axes of the human eye: the optical axis, visual axis, fixation axis, and pupillary axis. There are also three angles of the eye: angle kappa is formed between the pupillary axis and visual axis, angle alpha is formed between the optical axis and visual axis, and angle gamma is formed between the optical axis and fixation axis.
Corneal degeneration refers to conditions where the normal cells of the cornea undergo degenerative changes due to age or pathology. There are several types of corneal degenerations that can be classified based on location (axial or peripheral) and etiology (age-related or pathological). Common age-related peripheral degenerations seen in elderly individuals include arcus senilis, Vogt's white limbal girdle, and Hassall-Henle bodies. Arcus senilis appears as a grey or white ring around the peripheral cornea and is non-pathological. Vogt's white limbal girdle is similar but can occur in younger people and may be associated with hypercholesterolemia. Hassall-
This document describes various methods of illumination used with a slit lamp to examine different parts of the eye. Diffuse illumination allows for a general survey of the eye while optic section, parallelepiped, and retroillumination techniques are used to view specific structures like the cornea, lens, and vitreous in more detail. Different angles of illumination like tangential, conical beam, and oscillatory help observe surface textures, cells in the aqueous humor, and lens opacities. Precise illumination techniques are crucial for comprehensive eye exams.
Fluorescein angiography involves injecting a fluorescent dye called sodium fluorescein intravenously and using specialized cameras with excitation and barrier filters to take photos of the retina as the dye circulates. It has revolutionized the diagnosis of retinal vascular diseases since the 1960s by allowing visualization of blood flow and detection of leaks. Care must be taken with patients on beta-blockers or with iodine allergies, as rare severe reactions including anaphylaxis can occur.
1. Accommodation is the mechanism by which the eye changes its refractive power to focus on objects at different distances. It occurs when the ciliary muscle contracts, allowing the lens to become more curved and powerful.
2. Accommodation has two components - physical accommodation involving the actual deformation of the lens, and physiological accommodation involving the contractile power of the ciliary muscle. Terminologies like far point, near point, and amplitude of accommodation are used to describe accommodation.
3. Accommodation is assessed using tests like RAF rule, pushup test, and dynamic retinoscopy to measure the near point, amplitude, and accommodative response respectively. Assessment of dynamic accommodation involves testing accommodative facility using
what is Duochrome Test, Why do we take Red and Green color only,
What is the Principal of Duochrome Test, Why Hyperopic Pt sees green better than red and vice versa
Gonioscopy allows visualization of the anterior chamber angle structures. It was coined by Alexios Trantas in 1975 from the Greek words "gonia" meaning angle and "skopein" meaning to view. There are two main types - direct gonioscopy using a Koeppe lens which provides a panoramic view but no magnification, and indirect gonioscopy using a Goldmann lens which provides a segmented view through a mirror with excellent optics and the ability to perform indentation. Gonioscopy is used diagnostically to classify glaucoma and assess angle anatomy and closure risk, and therapeutically for procedures like laser trabeculoplasty.
The retina is the innermost layer of the eye that converts light into neural signals. It contains several layers of tissue and cell types that carry out this visual transduction process. The outermost layer contains pigmented cells, followed by photoreceptor cells (rods and cones), bipolar and ganglion cells that transmit signals to the brain. Within the retina, the macula provides high-acuity central vision and the optic disc is where retinal ganglion cell axons exit as the optic nerve. The retina receives its blood supply from the central retinal artery and precise vascular architecture is important for normal visual function.
The tear film has three layers:
1. A mucin layer secreted by goblet cells that forms a hydrophilic barrier on the cornea.
2. An aqueous layer secreted mainly by the lacrimal gland, containing proteins, electrolytes, and other components.
3. An outer lipid layer secreted by meibomian glands that prevents evaporation and maintains tear film stability.
The tear film is regulated by hormonal and neural pathways and provides nutrients to the cornea, removes waste, lubricates the eye, and protects against infection through its biochemical composition.
The document discusses the optical aberrations present in the normal human eye. It describes mechanisms that decrease aberrations, including the iris cutting peripheral rays, the high refractive index of the lens core, and retinal sensitivity patterns. The primary aberrations discussed are diffraction of light forming an airy disc pattern, spherical aberration bringing peripheral rays to different focal points than para-axial rays, coma aberration forming a comma shape, and chromatic aberration focusing different wavelengths to different depths. Decentering of the lens and oblique aberrations from peripheral vision are also mentioned.
An epiretinal membrane is an avascular fibrocellular membrane that grows on the inner surface of the retina, causing macular dysfunction. It consists of various cell types and collagen. Symptoms include blurry vision and metamorphopsia. Observation is usually sufficient for mild cases, but surgery is recommended for significant vision loss or distortion. Peeling the membrane improves vision in most cases, though cataracts are a common complication. Prognosis is better when pre-op vision is good and the duration of symptoms is short.
This document provides an overview of lasers used in ophthalmology. It discusses the history and physics of lasers, describing key laser characteristics and components. Different types of lasers are outlined, along with factors that determine laser tissue interaction and complications. Applications of lasers in anterior and posterior segment eye diseases are summarized. Delivery systems including slit lamps and scanning laser ophthalmoscopes are also covered, along with safety considerations.
The document summarizes key optical structures and properties of the eye. It describes the cornea as having a convex shape that refracts light and protects the eye. It then discusses the aqueous humor, crystalline lens, and vitreous humor, noting their roles in refraction due to differences in density. Schematic and reduced eye models are presented, including cardinal points and refractive indices. Common refractive errors like myopia and hyperopia are also outlined.
Keratometry is a technique used to measure the radius of curvature of the anterior corneal surface using an instrument called a keratometer. The keratometer utilizes the reflective properties of the cornea to measure the size of an image formed by reflection of an object of known size and position, allowing the radius of curvature to be calculated. Commonly, keratometers either use a fixed doubling system with variable mires or a variable doubling system with fixed mires. Measurements from keratometry are used to fit contact lenses and monitor corneal changes from contact lens wear.
Astigmatic lens used in ophthalmology and eyeRACHANA KAFLE
different types and classifications of astigmatic lens used
availability of astigmatic lens
uses of astigmatic lens
advantages and disadvantages of astigmatic lens
The document describes the components and uses of a trial box, which is a set of lenses, frames, and accessories used to test vision. It contains trial frames that hold spherical, cylindrical, and prismatic lenses in various diopters for refraction testing. Accessories include occluders, filters, charts, and tools like Maddox rods and cross cylinders. The trial box is used for objective and subjective refraction, diagnosing conditions like squint, and assessing binocular vision.
A lens clock is a mechanical device used to measure the curvature and optical power of a lens surface. It has three legs - two outer fixed legs and one inner movable leg. The difference in height between the inner and outer legs corresponds to the curvature of the lens surface. The lens clock converts this curvature measurement into a diopter value, assuming the lens material has a refractive index of 1.523. Rotating the lens clock allows measuring any cylindrical component of the lens. Adding the power readings from the front and back surfaces provides an estimate of the total lens power.
This document discusses various materials used in ophthalmic lenses. It describes the optical, mechanical, electrical, chemical and thermal properties of different lens materials like glass and plastics. Specifically, it provides details on the properties of different types of glass lenses including crown glass, flint glass, barium crown glass, and high index glass. It also discusses plastic lenses and highlights the use of high index lenses for higher prescriptions to reduce lens thickness.
The document discusses various theories of light, including Newton's corpuscular theory, Huygens' wave theory, Maxwell's electromagnetic theory, and Einstein's quantum theory. It also discusses key properties of light such as reflection, refraction, interference, polarization, diffraction, and dispersion. Optical science refers to the study of light and its interactions with matter. Light can be defined as energy that the human eye is sensitive to and exists in the electromagnetic spectrum between X-rays and microwaves.
These lectures has prepared for postgraduate student (Ophthalmology) according to the curriculum of Bangladesh College of Physician and Surgeons (BCPS) and Bangabondhu Sheikh Mujib Medical University (BSMMU) Bangladesh
Optical Phenomena related to Optometric Optics (Reflection, Refraction, Interference, Diffraction, Polarisation) and also their Optometric Uses or their uses in the Optometry Field
Optical Phenomena related to Optometric Optics (Reflection, Refraction, Interference, Diffraction, Polarisation) and also their Optometric Uses or their uses in the Optometry Field
This document is a 38-page seminar report on spectroscopy submitted by two students, Arpit Modh and Parth Kasodariya. It includes an introduction to spectroscopy, descriptions of various spectroscopy techniques like atomic absorption spectroscopy, infrared absorption spectroscopy, and ultraviolet-visible spectroscopy. The report covers principles, instrumentation, applications, and more for different spectroscopy methods. It aims to provide a basic review of spectroscopy and its uses in various important fields like structure analysis.
IR spectroscopy involves the interaction of infrared radiation with matter. It covers a range of techniques mostly based on absorption spectroscopy to identify chemical substances. The principle is that molecules absorb specific infrared frequencies characteristic of their structure. For instance, the molecule can absorb the energy in incident light, resulting in faster rotation or more pronounced vibration. Instrumentation includes an IR source, sample, detector, and processor to analyze absorbed frequencies. There are two main types of molecular vibrations observed: stretching and bending. Applications include identification of substances, studying reaction progress, and determining molecular structure.
These lectures has prepared for postgraduate student (Ophthalmology) according to the curriculum of Bangladesh College of Physician and Surgeons (BCPS) and Bangabondhu Sheikh Mujib Medical University (BSMMU) Bangladesh
Fourier transform IR (FTIR) machine for textile applicationBahirdar University
This document contains about textile application of FTIR machine which is mainly used for functional group and chemical bond identification of solid as well as liquid materials.
Infrared spectroscopy involves using infrared light to analyze chemical bonding and structure. A Fourier transform infrared spectrometer directs infrared light through a sample, and detects the wavelengths absorbed to produce a spectrum. This spectrum can be analyzed to determine molecular structure based on the vibrational and rotational energies absorbed corresponding to different chemical bonds like C-H, C=O, and N-H. Infrared spectroscopy is widely used for structural analysis in fields like organic chemistry, biology, physics, and engineering.
X-ray diffraction was discovered in 1895 by Wilhelm Röntgen. It involves using x-rays and analyzing the diffraction patterns formed after x-rays interact with the ordered structure of crystals. Bragg's law describes the conditions under which constructive interference of x-rays occurs leading to diffraction. X-ray diffraction is used to determine the atomic and molecular structure of crystals. It has applications in fields like materials science, chemistry, and structural biology.
spectroscopy, classification of spectroscopy, history, UV-VIS spectrophotometer, principle, beer lambert law instrumentation, detector, single beam, double beam in time, double beam in space, application, merits, and demerits
This document provides an introduction to spectroscopic methods of analysis. It defines spectroscopy as the study of interactions between electromagnetic radiation and matter. It describes the wave and particle properties of electromagnetic radiation and defines key terms related to waves like wavelength, frequency, speed of light. It discusses the components of optical instruments for spectroscopy including sources of radiation, wavelength selectors, radiation transducers, and signal processors. It also explains the differences between atomic and molecular transitions and different types of spectra.
Laser light interacts with tissues through thermal, photochemical and ionizing effects. Thermal effects include photocoagulation where laser energy generates heat to denature proteins, photodisruption where high energy causes optical breakdown and vaporization, and photovaporization. Photochemical effects involve photoablation which breaks bonds to vaporize tissue. The specific effect depends on wavelength, pulse duration and tissue absorption properties.
X-ray crystallography uses X-ray diffraction to determine the atomic and molecular structure of crystals. Monochromatic X-rays are generated by a cathode ray tube and directed at a crystalline sample. The regular arrangement of atoms in the crystal causes the X-rays to diffract into specific patterns determined by Bragg's law, providing information about the crystal structure. X-ray diffraction is widely used in fields like biochemistry, materials science, and engineering to study the structure of molecules, crystals, and solid materials.
Here are the answers to your questions:
1. To determine molar absorptivity (ε) and specific absorbtivity (A), measure the absorbance (A) of solutions with known concentrations (c) and pathlengths (l). Molar absorptivity is calculated as ε = A/cl. Specific absorbtivity is calculated as A = εcl.
2. The grating in a spectrophotometer functions to separate polychromatic light into its component wavelengths (monochromatic light). It does this via the principle of diffraction - the grating grooves act like multiple slits that diffract light at different angles depending on the wavelength.
3. The main parts of a mon
This lecture is based on medical students those are preparing for postgraduate degree namely FCPS/MS/MD/ any any subject coz hypertension is a systemic disease and by seeing the ocular fundus we can asses the general condition of blood vessels in major organ.
This lecture is based on post-graduate students of Ophthalmology (DO, DCO, MCPS, FCPS, MS) and optical principle of LASER, construction of laser and laser tissue interaction has cover the lecture
This lecture is based on post-graduate students of Ophthalmology (DO, DCO, MCPS, FCPS, MS) and optical principle of GAT has to know for a student to use the instrument friendly
This lecture is based on post-graduate medical students of all subject those who are students MS/MD/FCPS of different subject on Central Tendency and Dispersion.
A prism is defined as a portion of a refracting medium bordered by two plane surfaces which are inclined at a finite angle. It deviates light toward its base and causes objects to appear displaced toward its apex. Prisms are used diagnostically to measure ocular alignment and fusional reserves, and therapeutically to treat conditions like convergence insufficiency by strengthening the convergence reflex through base-out prism exercises.
The document discusses various topics related to spherical mirrors, including:
1) Spherical mirrors can be concave or convex depending on whether the silvering is on the outside or inside of the curved glass surface.
2) Key parts of spherical mirrors include the pole, center of curvature, radius of curvature, and principal axis.
3) Images formed by a concave mirror depend on the location of the object, which can be divided into five cases based on whether the object is beyond, at, or between the center of curvature and focal point, or at the focal point itself.
4) Depending on the object location, the image characteristics such as position, orientation, size and whether it is real
This is the 5 th lecture on "Research Methodology through zoom. The lecture was based on postgraduate Medical students those are different courses of FCPS/MS/MD/PhD (any Specialty)
This document discusses various conditions that affect the pupil, including Adie's tonic pupil, Argyll Robertson pupils, and pituitary adenomas. Adie's tonic pupil is caused by damage to the ciliary ganglion and results in a dilated, poorly reactive pupil. Argyll Robertson pupils are caused by neurosyphilis and show a dissociation between the light and near reflexes. Pituitary adenomas are tumors of the pituitary gland that can compress the optic chiasm and cause visual field defects such as bitemporal hemianopia. MRI is useful for evaluating these conditions.
Sample and Sampling Technique 3rd LectureAnisur Rahman
Cluster sampling is a sampling technique where the population is divided into naturally occurring groups or clusters, and then a sample of clusters is selected for analysis. The key aspects are that the population is divided into clusters first before sampling, and that sampling is done at the cluster level rather than individually. There are two main types of cluster sampling: one-stage, where all individuals in selected clusters are surveyed; and two-stage, where a random sample of individuals is selected from each cluster. Cluster sampling aims to reduce costs compared to simple random sampling while still achieving representation. However, it can result in larger sampling errors if clusters are not sufficiently heterogeneous.
Light can be defined as energy that the human eye can see. There are three broad subfields of optics: geometrical optics which studies light as rays, physical optics which studies light as waves, and quantum optics which studies light as particles. Geometrical optics includes the laws of reflection and refraction. Physical optics demonstrates that light exhibits wave properties through interference and diffraction. Quantum optics examines light at the quantum scale. Polarization and dispersion are also properties of light discussed in the document. Visual field loss in glaucoma can be detected earlier using blue light stimuli on a yellow background due to the eye's sensitivity to different wavelengths.
The document provides guidelines for writing a thesis protocol, including covering formatting requirements, sections to include such as objectives, methodology, and references, and tips for writing effective introductions, research questions/hypotheses, and objectives. It emphasizes following the guidelines of one's institution and writing concisely, clearly, and with appropriate references. Sample text is provided to demonstrate proper structure and formatting for each section of a thesis protocol.
The document discusses 15 different ophthalmic instruments used in various eye examinations and surgeries. For each instrument, the name, relevant procedure (e.g. cataract surgery), and potential complications are provided. The instruments include the Nettleship punctum dilator, trial frame, Schiotz tonometer, wire vectis, Simcoe cannula, phacoemulsification device, chalazion clamp, chalazion scoop, Barraquer needle holder, evisceration scoop, and instruments used in DCR surgery. Differences between immature and mature cataract and measurement of visual acuity with Snellen's chart are also summarized.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
8 Surprising Reasons To Meditate 40 Minutes A Day That Can Change Your Life.pptxHolistified Wellness
We’re talking about Vedic Meditation, a form of meditation that has been around for at least 5,000 years. Back then, the people who lived in the Indus Valley, now known as India and Pakistan, practised meditation as a fundamental part of daily life. This knowledge that has given us yoga and Ayurveda, was known as Veda, hence the name Vedic. And though there are some written records, the practice has been passed down verbally from generation to generation.
Does Over-Masturbation Contribute to Chronic Prostatitis.pptxwalterHu5
In some case, your chronic prostatitis may be related to over-masturbation. Generally, natural medicine Diuretic and Anti-inflammatory Pill can help mee get a cure.
Hiranandani Hospital in Powai, Mumbai, is a premier healthcare institution that has been serving the community with exceptional medical care since its establishment. As a part of the renowned Hiranandani Group, the hospital is committed to delivering world-class healthcare services across a wide range of specialties, including kidney transplantation. With its state-of-the-art facilities, advanced medical technology, and a team of highly skilled healthcare professionals, Hiranandani Hospital has earned a reputation as a trusted name in the healthcare industry. The hospital's patient-centric approach, coupled with its focus on innovation and excellence, ensures that patients receive the highest standard of care in a compassionate and supportive environment.
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
2. Properties of Electromagnetic waves
Electromagnetic waves share six properties with all
forms of wave motion:
1) Polarization 2)Interference
3) Diffraction 4) Dispersion
5) Reflection 6) Refraction
Here, 1 to 4 is physical optics and 5, 6 geometrical optic
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3. What is light?
Before discussing these properties we should have
clear idea about wave properties of light.
What is light?
Light may be defined as energy to which the human eye
is sensitive (Elkington. P: 1)
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4. There are seven domains of wavebands
1) Ultraviolet C (UV-C) 200 – 280 nanometer
2) Ultraviolet B (UV-B) 280 – 315 nanometer
3) Ultraviolet A (UV–A) 315 – 400 nanometer
4) Visible radiation 400-780 nanometer.
5) Infrared A (IR-A), 780-1400 nanometer.
6) Infrared B (IR-B), 1400-3000 nanometer.
7) Infrared C (IR-C), 3000-10000 nanometer.
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5. • The shorter the wavelength, the greater the energy of
the individual quanta.
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6. Absorption of light by eyeball
• The cornea and sclera of the eye absorb essentially all
the incident optical radiation at very short wavelength
in the ultraviolet (UV-B and UV-C) and long
wavelengths in the infrared (IR-B & IR-C)
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7. Absorption of light by eyeball
• The incident UV-A is strongly absorbed by the
crystalline lens while wavelengths in the range 400-
1400(visible light and near infrared) pass through the
ocular media to fall on the retina.
8. Absorption of light by eyeball
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• The visible wavelengths stimulate the retinal
photoreceptor giving the sensation of light while the
near infrared may give rise to thermal effects.
QUESTION.
• How eclipse burn causes retinal damage?
9. In the late 1600s, important questions were raised,
asking if light is made up of particles, or is it waves?
10. Sir Isaac Newton, held the theory that light was made
up of tiny particles.
By the help of Newton’s theory we can only prove
refraction and reflection of light
11. In 1678, Dutch physicist, Christiaan Huygens, believed
that light was made up of waves vibrating up and down
perpendicular to the direction of the light travels, and
therefore formulated a way of visualising wave
propagation. This became known as 'Huygens'
Principle'.
12. Waves have two important characteristics -
wavelength and frequency
13. Wavelength:
• Wavelength:
• This is the distance between peaks of a wave.
Wavelengths are measured in units of length - meters,
When dealing with light, wavelengths are in the order
of nanometres (1 x 10-9)
14. Frequency:
Frequency:
• This is the number of peaks that will travel past a
point in one second. Frequency is measured in cycles
per second. The term given to this is Hertz (Hz)
named after the 19th century discoverer of radio
waves - Heinrich Hertz. 1 Hz = 1 cycle per second
15.
16. Theory of Light
Light is based on three theory:
1. Newton: Particle theory
2. Huygens: Wave theory
3. Einstein: Quantum mechanics
17. Newton's theory came first, but the theory of Huygens,
better described early experiments. Huygens'
principle lets you predict where a given wavefront
will be in the future, if you have the knowledge of
where the given wavefront is in the present
18. In 1905 Albert Einstein light having characteristics of
both wave and particle theory. From work of Plank on
emission of light from hot bodies, Einstein suggested
that light is composed of tiny particles
called photons, and each photon has energy.
19. • Light theory branches in to the physics of quantum
mechanics, which was conceptualised in the twentieth
century. Quantum mechanics deals with behaviour of
nature on the atomic scale or smaller.
• As a result of quantum mechanics, this gave the proof
of the dual nature of light and therefore not a
contradiction.
20. The wave moves energy—without moving mass—from
one place to another at a speed independent of its
intensity or wavelength.
This wave nature of light is the basis of physical optics
and describes the interaction of light with media. Many
of these processes require calculus and quantum theory
to describe them rigorously.
21. So light is based on three theory:
1. Newton: Particle theory
2. Huygens: Wave theory
3. Einstein: Quantum mechanics
22. Picture of a light wave
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23. light wave
The maximum value of the wave displacement is
called the amplitude (A) of the wave.
The cycle starts at zero and repeats after a distance.
This distance is called the wavelength (λ).
Light can have different wavelengths. The inverse of
the wavelength (1/λ) is the wave number (ν), which
is expressed in cm–1.
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24. light wave
The wave propagates at a wave speed (v). This wave
speed in a vacuum is equal to c, and is less than c in a
medium.
At a stationary point along the wave, the wave passes
by in a repeating cycle. The time to complete one
cycle is called the cycle time or period
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25. light wave
Another important measure of a wave is its
frequency (f). It is measured as the number of
waves that pass a given point in one second. The unit
for frequency is cycles per second, also called hertz
(Hz).
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26. light wave
• As we can see, the frequency and the period are
reciprocals of one another. If the wave speed and
wavelength are known, the frequency can be
calculated.
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27.
28. Polarization: What to read?
1) What is Polarization?
2) How light is polarized?
3) Application of polarized light
4) Birefringence
5) Applications of Birefringence
29. What is Polarization?
Light waves are travelling may or may not be parallel
to each other. If directions are randomly related to
each other the light is UNPOLARIZED/ NONPOLARIZED.
If parallel to each other is called POLARIZED.
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33. Polarization by Use of a Polaroid Filter
The most common method of polarization involves the
use of a Polaroid filter. Polaroid filters are made of a
special material that is capable of blocking one of the
two planes of vibration of an electromagnetic wave In
this sense, a Polaroid serves as a device that filters out
one-half of the vibrations upon transmission of the light
through the filter.
34. When unpolarized light is transmitted through a Polaroid
filter, it emerges with one-half the intensity and with
vibrations in a single plane; it emerges as polarized light.
35. How light is polarized?
Polarized light is produced from ordinary light by an
encounter with a polarizing substances or agent.
Polarizing substances, e,g. calcite crystal, only
transmit light rays which are vibrating in one
particular plane. Thus only a proportion of incident
light is transmitted onward and the emerging light is
polarized.
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36. How light is polarized?
A polarizing medium reduces radiant intensity but
does not affect spectral composition.
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37. Application of polarized light
Polarized sunglasses to exclude selectively the
reflected horizontal polarized light. Such glasses are
of great use in reducing glare from the sea or wet
roads.
Instruments: (to reduced reflected glare from the
cornea) example: Slit lamp Ophthalmoscope
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38. Application of polarized light
Binocular vision polarizing glass – May be used to
dissociate the eyes i,e in Titmus test
Also used in pleoptic to produced Haidinger’s
brushes and in optical lens making to examine lens
for stress.
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39. Birefringence
Some substances have double refractive index though
they transmit light into 2 direction and they are called
Birefringence
A widely used birefringent material is Calcite Its
birefringence is extremely large, with indices of
refraction for the o- and e-rays of 1.6584 and 1.4864
respectively.
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41. Applications of Birefringence
Birefringence finds use in the following applications:
Polarizing prisms and retarder plates
Liquid crystal displays
Medical Diagnostics
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42. Interference: What to read?
1) Some basic concepts of light wave
2) Conditions for Interference
3) Superposition: constructive interference &
destructive interference.
4) What is coherent source?
5) Types of interference
43. 2. Interference
• When two light waves from different coherent
sources meet together, then the distribution of energy
due to one wave is disturbed by the other. This
modification in the distribution of light energy due to
super- position of two light waves is called
"Interference of light"
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44. Conditions for Interference
The two sources of light should emit continuous
waves of same wavelength and same time period i.e.
the source should have phase coherence.
The two sources of light should be very close to each
other. The waves emitted by two sources should
either have zero phase difference or no phase
difference.
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46. Coherent sources
Those sources of light which emit light waves
continuously of same wavelength, and time
period, frequency and amplitude and have
zero phase difference or constant phase
difference are coherent sources.
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47. Types of interference
There are two types of interference.
1) Constructive interference.
2) Destructive interference
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50. constructive interference
When two light waves superpose with each other in
such away that the crest of one wave falls on the crest
of the second wave, and trough of one wave falls on
the trough of the second wave, then the resultant
wave has larger amplitude and it is called constructive
interference
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51. destructive interference
When two light waves superpose with each other in
such away that the crest of one wave coincides
the trough of the second wave, then the amplitude
of resultant wave becomes zero and it is
called destructive interference.
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53. Diffraction
The term diffraction, from the Latin diffringere, 'to
break into pieces', referring to light breaking up
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54. Concept of diffraction
Diffraction is the bending of waves around obstacles,
or the spreading of waves by passing them through an
aperture, or opening.
Any type of energy that travels in a wave is capable
of diffraction, and the diffraction of sound and light
waves produces a number of effects.
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55. Concept of diffraction
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Diffraction of light waves, is much more complicated,
and has a number of applications in science and
technology, including the use of diffraction gratings in
the production of holograms.
57. Observing Diffraction in Light
• Wavelength of light plays a role in diffraction; so,
too, does the size of the aperture relative to the
wavelength. Hence, most studies of diffraction in
light involve very small openings, as, for instance, in
the diffraction grating.
• But light does not only diffract when passing through
an aperture, it also diffracts around obstacles.
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58. Observing Diffraction in Light
• When light passes through an aperture, most of the
beam goes straight through without disturbance, with
only the edges experiencing diffraction. If, however,
the size of the aperture is close to that of the
wavelength, the diffraction pattern will widen. when
light is passed through extremely narrow openings, its
diffraction is more noticeable.
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59. Diffraction Grating
• A diffraction grating is an optical device that consists of not
one but many thousands of apertures: Rowland's machine used
a fine diamond point to rule glass gratings, with about 15,000
lines per in (2.2 cm). Diffraction gratings today can have as
many as 100,000 apertures per inch.
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60. • The apertures in a diffraction grating are not mere
holes, but extremely narrow parallel slits that
transform a beam of light into a spectrum.
• Each of these openings diffracts the light beam, but
because they are evenly spaced and the same in
width, the diffracted waves experience constructive
interference.
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61. • This constructive interference pattern makes it
possible to view components of the spectrum
separately, thus enabling a scientist to observe
characteristics ranging from the structure of atoms
and molecules to the chemical composition of stars.
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62. • You may also notice that the light is alternately bright
and dark as you look through the curtain. This is
from interference. The bright places are where light
waves are adding together. The dark places are where
the waves cancel. With visible light, interference
always occurs with diffraction.
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63. DISPERSION
The separation of visible light into its different colors
is known as dispersion.
The optical density is simply a measure of the
tendency of a material to slow down light as it travels
through it.
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