This document discusses opportunities in interventional oncology. It provides information on various interventional radiology procedures for cancer including angiography, biopsy, drainage, tumor ablation, brachytherapy delivery, embolotherapy, and local delivery of chemotherapy. Examples of treatments used in local hospitals are discussed such as TAE, TACE, and ethanol ablation for liver cancer. Ratings and comments are provided on treatment options for different cases of hepatocellular carcinoma and metastatic liver disease.
Locally advanced Ca prostate
Courtesy : NCCN , Perez, Gunderson and Tepper
Brief outline on management
ADT, Radiotherapy, Surgery indications and Standard of care
Role Of Integrated Pet-Ct In Cancer of Unknown PrimaryApollo Hospitals
Whilst earlier Whole body CT played an important role in detecting the primary site presently, Integrated Positron emission tomography (PET) and computed tomography (CT) can play an important role in patients with unknown primary as it combines the advantage of cross sectional imaging with the diagnostic advantages of PET.
FDG PET/CT plays an important role in staging, restaging, prognostication, planning treatment strategies, monitoring therapy, and detecting relapse. In this lecture I try my best to explain it for our fellows .
Soft tissue sarcomas, treatment (surgical, radiation, chemotherapy)Joseph A. Di Como MD
A PowerPoint presentation for medical professionals regarding soft tissue sarcomas, likely most helpful to surgical residents and medical students. Gist tumors, liposarcomas, retroperitoneal sarcomas extremity, breast sarcoma and vascular sarcomas
Locally advanced Ca prostate
Courtesy : NCCN , Perez, Gunderson and Tepper
Brief outline on management
ADT, Radiotherapy, Surgery indications and Standard of care
Role Of Integrated Pet-Ct In Cancer of Unknown PrimaryApollo Hospitals
Whilst earlier Whole body CT played an important role in detecting the primary site presently, Integrated Positron emission tomography (PET) and computed tomography (CT) can play an important role in patients with unknown primary as it combines the advantage of cross sectional imaging with the diagnostic advantages of PET.
FDG PET/CT plays an important role in staging, restaging, prognostication, planning treatment strategies, monitoring therapy, and detecting relapse. In this lecture I try my best to explain it for our fellows .
Soft tissue sarcomas, treatment (surgical, radiation, chemotherapy)Joseph A. Di Como MD
A PowerPoint presentation for medical professionals regarding soft tissue sarcomas, likely most helpful to surgical residents and medical students. Gist tumors, liposarcomas, retroperitoneal sarcomas extremity, breast sarcoma and vascular sarcomas
Laparoscopic Partial Nephrectomy of Hilar Tumors with Cold Ischemiaguestd58ac53
Laparoscopic Partial Nephrectomy of Hilar Tumors with Cold Ischemia
Juza Chen and Avi Bery
Director of Sexual Dysfunction Clinic
Department of Urology
Tel-Aviv Sourasky Medical Center
Sackler Faculty of Medicine Tel-Aviv University
Moscow 2010
O. Glehen - HIPEC in colorectal carcinomatosisGlehen
Pr Olivier Glehen presents HIPEC in colorectal carcinomatosis in Slovenia 2013. Présentation de la CHIP dans la carcinose péritonéale d'origine colorectale.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Triangles of Neck and Clinical Correlation by Dr. RIG.pptx
Opportunities in interventional oncology by henry wanga
1. Opportunities in interventional oncology
Dr. Henry Wanga
Consultant Interventional Radiologist
Zenith Medical Centre
General Accident Insurance House
Ralph Bunche Road, Upper Hill Nairobi
2. KESHO
Kenya Society of Hematology and Oncology Third
Annual Scientific Conference
Panafric Hotel, Nairobi Kenya
28th November 2014
3. Angiography, Biopsy and Drainage
Interventional Radiology(IR) is a clinical subspecialty with a rich history of
innovations
We approach our work through clinical problem solving with our referring
specialists
Many IR practices have shifted from peripheral vascular interventions to
interventional oncology
Multimodal imaging methods have superseded the traditional arteriography
Embolic agents can be permanent, temporary, or combined with an agent
such as chemotherapy
Pelvic malignancies may cause lower extremity deep vein thrombosis.
Treatment is by placing permanent or temporary inferior vena cava filters
Complications in IR practice are uncommon
4. Oncologic applications
VASULAR
A. diagnostic information(e.g. vascular invasion, biopsy)
Diagnosis and treatment of associated conditions,(DVT,
central venous access, hemorrhage)
Local delivery of chemotherapy
Embolotherapy
Brachytherapy delivery
2. NON-VASCULAR
Diagnostic information(PTHC, biopsy)
Treatment of associated conditions (e.g. GI/GU/ biliary
obstruction)
Local tumor ablation(RF/ thermal, ethanol,acetic
acid,cisplatin -epigel)
5. Continued Oncologic applications
Brachytherapy delivery
3. Disease control vs. palliation
4. Connections with Basic Science(small animal, cellular
culture, etc) and Clinical Research(clinical trials)
7. Agents used in embolization treatment
of malignancies
Gelfoam sponge temporary –haemostasis
Poly vinyl alcohol particles (PVA) - permanent occlusion.
Comes in sizes 100, 200, 300, 500,700,or 1000 microns
Drug eluting beads (DEB)
Coils
8. Chemo infusion Agents
Cisplatin
Doxorubicin
Mitomycin c
Paclitaxel
And many others
9. Hepatocellular carcinoma: Solitary
tumor <3 cm
Treatment/Procedure Rating Comments
Systemic chemotherapy 3
Resection 8
Transplantation 9
Chemical ablation 6
Thermal ablation 8
Tran arterial embolization (TAE) 5
Tran arterial chemoembolization (TACE) 5
Selective internal radiation therapy (SIRT) 5
Rating Scale: 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate
10. Hepatocellular carcinoma: Solitary
tumor 5 cm
Treatment/Procedure Rating Comments
Systemic chemotherapy 3
Resection 8
Transplantation 9
The tumor is too large for chemical ablation. May
Chemical ablation 3 use it instead of or in addition to thermal ablation
depending on tumor location.
Thermal ablation 5
Tran arterial embolization (TAE) 6
Tran arterial chemoembolization (TACE) 7
Selective internal radiation therapy (SIRT) 7
Especially applicable in portal vein thrombosis or
extensive bilobar disease.
Transarterial chemoembolization (TACE)
7
combined with thermal ablation
Rating Scale: 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate
11. Metastatic liver disease: Multifocal colorectal carcinoma (liver
dominant or isolated), 5 cm
tumors.
Treatment/Procedure Rating Comments
Systemic chemotherapy 9
Resection 7
Transplantation 1
Chemical ablation 1
Thermal ablation 2
Hepatic arterial chemotherapy infusion 5
Transarterial embolization (TAE) 5
Transarterial chemoembolization (TACE) 5
Selective internal radiation therapy (SIRT) 5
Transarterial chemoembolization (TACE)
5
Depends on tumor burden.
combined with thermal ablation
Rating Scale: 1,2,3 Usually not appropriate; 4,5,6 May be appropriate; 7,8,9 Usually appropriate
15. IGS for Interventional Oncology
Innova* Image Guided Systems (IGS) for Interventional
Oncology provide excellent image quality with
exceptional dose efficiency. Get excellent organ coverage
for tumor embolization, ablation techniques, and 3D
guidance. Our flagship Innova IGS 540 with the Innova
CT option enhances soft tissue visualization for imaging
of high- and low-density tissues.
25. Discussion
Hepatocellulacr carcinoma is the most common primary
malignancy of the liver
Predisposed in patients with chronic liver diseases such as
cirrhosis, hemochromatosis, alcoholism and glycogen
storage disease
Hepatitis Chas been attributed to lead to increase HCC in
the United States. Age at presentation is in the sixth and
seventh decades
In Kenya the incidence is in the fourth and fifth decades
26. Major patterns of growth of HCC
Solitary mass
Multifocal masses
Diffusely infiltrating mass
27. Hepatic metastasis
This is the most common malignancy of the liver arising
from the colon, stomach, pancreas, breast, and lung
neoplasm
In children, metastases are commonly from neuroblastoma
and Wilm’s tumor
Prognosis depends on the primary tumor site.
31. Acknowledgements
Aga Khan University hospital, Karachi, Pakistan
Lifestyle, hospital, Pretoria
The Nairobi Hospital
Many colleagues; Dr. Abwao, Dr. Njuguna, Dr.
Ndagwatha, Dr. Githaiga, Dr. Otele, Dr. Nyongesa, Dr.
Ochieng( now studying in South Africa)
Radiology colleagues especially the late Dr. Sara Goretti
Tata
Colleagues at Mulago Hospital, Makerere University,
Kampala Uganda
Indeed all of YOU