This document provides an introduction and overview of the proposed Texas Cancer Centre project in Kenya. It notes that Jipsy Contractors was the first local construction company to construct a cancer centre in Kenya. It highlights some of the construction details like thick concrete walls and deep ceilings. The document expresses gratitude to the client, consultants, subcontractors, and specialists who worked together to successfully complete the project.
Marine & Shipyard Recruitment has a wide exposure when we talk about overseas jobs in the Gulf and Middle East area. AJEETS being in the forefront since the past decade is well capable of driving more recruiting companies and employers to absorb higher number of marine and shipyard industry candidates.
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Looking for an admirable Sanitary Ware in Singapore? Wan Tai & Co Pte Ltd is specialized in providing the ideal and designer quality sanitary wares for your dream bathroom. Without compromising with the quality, their products range between the reasonable medium-range to the ravishing high-range price. So you have a variety to browse from.
Marine & Shipyard Recruitment has a wide exposure when we talk about overseas jobs in the Gulf and Middle East area. AJEETS being in the forefront since the past decade is well capable of driving more recruiting companies and employers to absorb higher number of marine and shipyard industry candidates.
A core drill is a specialized drill with a hollow center, designed to carve a hole through a surface and extract a solid cylindrical sample from the drilled material. See more:
https://freerest.net/services/core-drilling/
Looking for an admirable Sanitary Ware in Singapore? Wan Tai & Co Pte Ltd is specialized in providing the ideal and designer quality sanitary wares for your dream bathroom. Without compromising with the quality, their products range between the reasonable medium-range to the ravishing high-range price. So you have a variety to browse from.
Amiante Str - Asbestos Removal in a Domestic PropertyJan Alvino
The presence of asbestos cement was suspected in the loft space of a domestic property in Portsmouth. Amiante STR surveyed the property and subsequently removed the asbestos, enabling the Client to qualify for free insulation under the Government’s Energy Companies’ Obligation Scheme.
Trenchless Technology - A Modern and Innovative Approach to Infrastructure Re...IMC Nukote Canada
This presentation delves into the realm of trenchless technology, an advanced and forward-looking approach to revitalize infrastructure. Explore how trenchless techniques, championed by IMC Distributors and industry partners, are reshaping rehabilitation and installation processes with innovation at the forefront. Discover how these methods minimize disruption, reduce costs, and contribute to sustainable development while ensuring the longevity of critical infrastructure.
Indigenous contractor providing a wide range of engineering, construction, maintenance and support services across the public and private sectors. People are our most valuable asset.
Kennelly's "can do" teams complete work safely, on time, and on budget.
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Design packaging for the elderly and persons with disabilities. Submit your entries by 30 September at www.ncc-challenge.com!
Powered by ICMG and Sustainable Living Lab (SL2)
Amiante STR Ltd were instructed by a domestic customer in late August to remove approx. 70 linear metres of asbestos pipe lagging to pipework located beneath the flooring within a flat valued at over £1m. The owner was undertaking a refurbishment of the property and required the removal of the asbestos.
Durable Work is the most trusted customer oriented MEP Contractors in Abu Dhabi Lots of mechanical companies in UAE offering HVAV, MEP, fit out works, ducting works, interior desiging works for residentical and commercial places for the best Use Durableworks Hvac Contractors Abu Dhabi
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Amiante Str - Asbestos Removal in a Domestic PropertyJan Alvino
The presence of asbestos cement was suspected in the loft space of a domestic property in Portsmouth. Amiante STR surveyed the property and subsequently removed the asbestos, enabling the Client to qualify for free insulation under the Government’s Energy Companies’ Obligation Scheme.
Trenchless Technology - A Modern and Innovative Approach to Infrastructure Re...IMC Nukote Canada
This presentation delves into the realm of trenchless technology, an advanced and forward-looking approach to revitalize infrastructure. Explore how trenchless techniques, championed by IMC Distributors and industry partners, are reshaping rehabilitation and installation processes with innovation at the forefront. Discover how these methods minimize disruption, reduce costs, and contribute to sustainable development while ensuring the longevity of critical infrastructure.
Indigenous contractor providing a wide range of engineering, construction, maintenance and support services across the public and private sectors. People are our most valuable asset.
Kennelly's "can do" teams complete work safely, on time, and on budget.
Launch of Next-Gen Packaging Design Challengesl2square
Slides presented at the Launch of the Next-Gen Packaging Design Challenge by Nippon Closures.
Design packaging for the elderly and persons with disabilities. Submit your entries by 30 September at www.ncc-challenge.com!
Powered by ICMG and Sustainable Living Lab (SL2)
Amiante STR Ltd were instructed by a domestic customer in late August to remove approx. 70 linear metres of asbestos pipe lagging to pipework located beneath the flooring within a flat valued at over £1m. The owner was undertaking a refurbishment of the property and required the removal of the asbestos.
Durable Work is the most trusted customer oriented MEP Contractors in Abu Dhabi Lots of mechanical companies in UAE offering HVAV, MEP, fit out works, ducting works, interior desiging works for residentical and commercial places for the best Use Durableworks Hvac Contractors Abu Dhabi
https://www.durableworks.ae/
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This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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2. PROPOSED TEXAS CANCER CENTRE:
Introduction:
Company Name, Date of Incorporation and Works done by Jipsy Contractors.
Our Journey Started on 15th August 2013 : Vote of Thanks the Client (Dr. Nyongesa)
and The Consultant Team(The Centric Architects, Build AFRIQUE, ABBA and Wandu,
Eriharst, Larry and Team) - Jipsy Contractors the 1st Local Construction Company to
construct a Cancer Centre in Kenya.
- During the Construction Project, (R.C. 2.1 thick walls, 3 metre deep ceiling,
Isocentre reference point, Scope of work). All hard work and Site Meetings went
into the successful completion of the Project and the end product is truly worth
the input.
- Good to see the friendship between Client, Consultants and the Contractors there
after completion of the works.
- We also Like to Thank our Sub Contractors and Specialists on the Project:-
a. Electrical Sub – Muga Electric – Lead by Mr. Andrew Mugo
b. Mechanical Sub – Wena Technical Services – Lead by the Late Mr. Noah
Omusolo …..Tribute to him
c. Structured Cabling – Iconet Solutions – Lead by Mr. George Kyeno
d. Mechanical Vent. – Seven Fourteen – Lead by Mr. Joshua Musembi
e. Notable Mentions – Textured Paint works – NDesign, Joinery Works – Tidy
