This document provides an overview of the anatomy of the central nervous system (CNS). It describes in detail the structures of the skull, meninges, dural sinuses, cerebrospinal fluid circulation, parts of the brain including the cerebrum, cerebral hemispheres, lobes, sulci and gyri, brainstem, cerebellum, limbic system, and suprasellar region. The document focuses on the anatomical structures and their locations within the CNS.
This presentation provides a comprehensive review of major sulci of brain which help in defining the different lobes of brain.Very useful for first year residents.
Cisterns of brain and its contents along with its classification and approach...Rajeev Bhandari
This presentation tell us about the basic of cistern , according to its classification both supra tentorial and infratentorial along with ventral and dorsal cistern. basically the cistern contains are well explained on this slide nerve , artery and vein. I hope it will help to rembember well about the contains of cistern and different location of cisterns.
This presentation provides a comprehensive review of major sulci of brain which help in defining the different lobes of brain.Very useful for first year residents.
Cisterns of brain and its contents along with its classification and approach...Rajeev Bhandari
This presentation tell us about the basic of cistern , according to its classification both supra tentorial and infratentorial along with ventral and dorsal cistern. basically the cistern contains are well explained on this slide nerve , artery and vein. I hope it will help to rembember well about the contains of cistern and different location of cisterns.
Neocortex, paleocortex and archicortex coexist in temporal lobe
makes it preferred site for epilepsy
avoidance of visual pathways (optic tract, lateral geniculate body Meyer’s loop, and optic radiations)
White matter pathways involved in the neurocognitive sequelae
extent of the incision to the temporal stem,
extent of amygdalectomy
avoidance of vascular injury.
Objectives of this presentation are
Introduction to ct
Cross sectional anatomy
Common important pathologies
This presentation is aimed to educate beginers to help in ct interpretetion.
Neocortex, paleocortex and archicortex coexist in temporal lobe
makes it preferred site for epilepsy
avoidance of visual pathways (optic tract, lateral geniculate body Meyer’s loop, and optic radiations)
White matter pathways involved in the neurocognitive sequelae
extent of the incision to the temporal stem,
extent of amygdalectomy
avoidance of vascular injury.
Objectives of this presentation are
Introduction to ct
Cross sectional anatomy
Common important pathologies
This presentation is aimed to educate beginers to help in ct interpretetion.
Neurosurgery involving the cerebrum, the largest and most prominent part of the brain, encompasses a wide range of procedures aimed at addressing various neurological conditions.
The cerebrum is responsible for higher cognitive functions, sensory perception, motor control, and emotional processing.
Neurosurgery involving the cerebrum requires a multidisciplinary approach, combining neuroimaging, neurophysiology, and advanced surgical techniques to address diverse neurological conditions while preserving critical brain functions.
Description :
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The brain stem is a critical part of the human brain that connects the brain to the spinal cord.
It plays a vital role in basic life functions and serves as a bridge between the higher brain centers (such as the cerebral cortex) and the rest of the body.
The brain stem is responsible for essential functions such as breathing, heart rate, blood pressure, and basic reflexes.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Adv. biopharm. APPLICATION OF PHARMACOKINETICS : TARGETED DRUG DELIVERY SYSTEMSAkankshaAshtankar
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ADVANCED BIOPHARMACEUTICS & PHARMACOKINETICS : UNIT 5
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Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
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1. Normal and Abnormal
Radiology of CNS (Part I)
Mohammed Fathy Bayomy, MSc, MD
Lecturer
Clinical Oncology & Nuclear Medicine
Faculty of Medicine
Zagazig University
55. Borders
Each cerebral hemisphere
has three border
I. Superomedial border.
II. Inferomedial border.
III.Inferolateral border.
Cerebral Hemispheres
Cerebrum
56. Surfaces
Each cerebral hemisphere
has three surfaces
I. Superolateral surface
II. Medial surface
III.Inferior surface.
Cerebral Hemispheres
Cerebrum
57. Superolateral surface
It follows the concavity of the cranial vault
Medial surface
It is flat and vertical and separated from its fellow by the great
longitudinal fissure and falx cerebri.
Inferior surface
Inferior surface or the basal surface is irregular and divided
into orbital and tentorial surface.
Cerebral Hemispheres
Cerebrum
60. Occipital pole
Frontal pole
Temporal pole
Poles
Each cerebral hemisphere
has three poles
I. Frontal pole.
II. Occipital pole.
III.Temporal pole
Cerebral Hemispheres
Cerebrum
61. Lobes
Each cerebral hemisphere has
six lobes
1) Frontal lobe.
2) Parietal lobe.
3) Occipital lobe.
4) Temporal lobe.
5) Insular lobe.
6) Limbic lobe.
Cerebral Hemispheres
Cerebrum
65. Sulci and Gyri
• Each cerebral hemisphere shows a
complex pattern of convulation called
Gyrus.
• The gyruses are separated by furrows of
varying length called Sulci.
• The convulated structure increases the
cortical volume to three times what it
would be if the surface is smooth.
• The area of the cerebral cortex is 2200cm²
Cerebral Hemispheres
Cerebrum
68. (I) Lateral (Sylvian) sulcus
• Deep cleft on lateral &
inferior surface
• It has a stem which
divides into three rami:
anterior, ascending,
posterior.
• The floor of the posterior
ramus is insula which is
hidden cortex.
Cerebral Hemispheres
Cerebrum
69. (II) Central sulcus
• It is the boundary between frontal and parietal lobes
• It starts at the superomedial border, a little behind the
midpoint between frontal and occipital poles. It runs
downwards and forwards for about 8-10cm to end little
above the posterior ramus of lateral sulcus.
• It demarcates the motor and sensory area of the cerebral
cortex.
Cerebral Hemispheres
Cerebrum
74. Medial surface
In the medial surface
The commissural fibres of
the corpus callosum lies
in the depth of
longitudinal fissure
Parts of corpus callosum
oRostrum
oGenu
oTrunk or body
oSplenium
The anterior part divided
into outer and inner zone
by cingulate sulcus
Cerebral Hemispheres
Cerebrum
76. Sulcus and Gyrus
The posterior region of the medial surface is traversed by
parieto-occipital and calcarine sulcus. The parieto-
occipital sulcus marks the boundary between parietal and
occipital lobes.
The visual cortex lies above and below the calcarine
sulcus.
In the inferior cerebral surface
Olfactory sulcus
Rhinal sulcus
Occipitotemporal sulcus
Collateral sulcus
Cerebral Hemispheres
Cerebrum
81. -Present within the lateral sulcus
Between temporal and frontal
Lobe.
-The overlying cortical areas are
called opercula formed from the
parts of frontal,temporal and
parietal lobe
-Functions linked to emotion and
body’s homeostasis
-i.e perception,motor control,self
awarness,congnitive functioning
interpersonal experience
Insula
Cerebral Hemispheres
Cerebrum
82. White matter of cerebrum
Consists of myelinated nerve
fibres which are categorized on
the basis of their course and
connections
A. Association fibres
• It links different cortical areas of
the same hemisphere
• Two types
i. Short association fibres
They are entirely intracotical
Some merely pass from one wall
of the sulcus to other.
ii. Long association fibres
They are present in bundles
Example: uncinate
fasciculus,cingulum,superior
longitudinal fasciculus,etc
Cerebral Hemispheres
Cerebrum
83. Commissural(transverse)
fibres
Commissural fibres cross the
midline, linking
corresponding areas in the
two cerebral hemisphere.
The largest commissure is
the corpus callosum.
Other commissures are
oAnterior
oPosterior
oHabenular
oCommissure of fornix.
White matter of cerebrum
Cerebral Hemispheres
Cerebrum
84. Projection fibres
Projection fibres connect
cerebral cortex with lower
levels in the brain and
spinal cord.
Consists of both
coticofugal and
corticopetal fibres
Corticofugal fibres
converge from all
directions to form corona
radiata.
Corona radiata continous
with the internal capsule.
White matter of cerebrum
Cerebral Hemispheres
Cerebrum