This document discusses how new sensor and intelligent device technologies have the potential to transform healthcare delivery by bringing care closer to patients' homes. It describes how these non-intrusive technologies could enable patients to recover more quickly after surgery and benefit from virtual reality applications. The document also examines how wearable devices and sensors that can monitor vital signs could support more integrated, patient-centered care models by reducing dependence on providers and facilitating remote care, monitoring and early detection of health issues. Machine learning and big data analytics are discussed as ways to generate insights from the large and growing volumes of patient data that these new digital devices and sensors are capturing.