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Histology practical 1
(Histology of Pituitary & Thyroid & Parathyroid glands)
By :
Osama Al-Zahrani
@OSAMA_Z96
&
Osama Hassan Al-Ghamdi
1- Pituitary Gland
* Component & Characteristics :
1- Pars Distalis.
2- Pars Intermedia (Corticotrophs).
3- Pars Nervosa.
4- Pituicytes (Neuroglia).
5- Neurosecretory Bodies (Herring Bodies) :
A- Oxytocin.
B- Antidiuretic hormone (ADH).
* Function :
- Anterior Pituitary gland :
Synthesizes and secretes hormones.
- Posterior Pituitary gland :
Store and secretes hormones (Oxytocin & ADH) .
* Histopathological Lesion :
- Pituitary adenoma.
2- Pars distalis
(Anterior Pituitary gland)
* Component & Characteristics :
1- Blood capillary (Sinusoidal).
2- Chromophobs 50%
3- Chromophils 50% (50% = 34% Acidophils & 16% Basophils ):
4- Acidophils 66% : (GH & PRL).
5- Basophils 33% :
A- Thyrotrophs : (TSH).
B- Corticotrophs : (ACTH, MSH, Lipotropic LPH)
C- Gonadotrophs : (LH, ICSH, FSH).
* Function :
Synthesizes and secretes hormones.
* Histopathological Lesion :
- Pituitary adenoma.
Blood Capillary
3- Thyroid Gland & Thyroid follicle
* Component & Characteristics :
1- Capsule.
2- Interfollicular cells.
3- Thyroid follicle :
A- C-cell (Parafollicular) :
- Clear.
- Calcitonin.
- Catecholamines (Epinephrine & Nor-epinephrine).
C- Thyrocytes (Follicular cells)
D- Colloid (Thyroglobulin)
* Function :
1- C-cell :
Produces calcitonin and catecholamines.
2- Follicular cells :
Secretion of T3 & T4
* Histopathological Lesion :
1- Thyroid adenoma.
2- Hashimoto thyroiditis.
Interfollicular cells
C-cell
Thyrocyte
4- Parathyroid Gland
* Component & Characteristics :
1- Thin capsule.
2- Chief (Principal) cells :
- Parathyroid hormone (PTH).
3- Oxyphil cells (acidophilic) :
- Degenerated chief cells.
- Some Parathyroid hormone (PTH).
4- Colloid (homogeneous gel).
5- Blood vessel.
* Function :
- Regulation of Ca in blood (hypercalcemic).
* Histopathological Lesion :
- Parathyroid adenoma.
Thin capsule of parathyroid gland
Histology (histology of pituitary, thyroid, and parathyroid glands)

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Histology (histology of pituitary, thyroid, and parathyroid glands)

  • 1. Histology practical 1 (Histology of Pituitary & Thyroid & Parathyroid glands) By : Osama Al-Zahrani @OSAMA_Z96 & Osama Hassan Al-Ghamdi
  • 2. 1- Pituitary Gland * Component & Characteristics : 1- Pars Distalis. 2- Pars Intermedia (Corticotrophs). 3- Pars Nervosa. 4- Pituicytes (Neuroglia). 5- Neurosecretory Bodies (Herring Bodies) : A- Oxytocin. B- Antidiuretic hormone (ADH). * Function : - Anterior Pituitary gland : Synthesizes and secretes hormones. - Posterior Pituitary gland : Store and secretes hormones (Oxytocin & ADH) . * Histopathological Lesion : - Pituitary adenoma.
  • 3.
  • 4. 2- Pars distalis (Anterior Pituitary gland) * Component & Characteristics : 1- Blood capillary (Sinusoidal). 2- Chromophobs 50% 3- Chromophils 50% (50% = 34% Acidophils & 16% Basophils ): 4- Acidophils 66% : (GH & PRL). 5- Basophils 33% : A- Thyrotrophs : (TSH). B- Corticotrophs : (ACTH, MSH, Lipotropic LPH) C- Gonadotrophs : (LH, ICSH, FSH). * Function : Synthesizes and secretes hormones. * Histopathological Lesion : - Pituitary adenoma. Blood Capillary
  • 5.
  • 6. 3- Thyroid Gland & Thyroid follicle * Component & Characteristics : 1- Capsule. 2- Interfollicular cells. 3- Thyroid follicle : A- C-cell (Parafollicular) : - Clear. - Calcitonin. - Catecholamines (Epinephrine & Nor-epinephrine). C- Thyrocytes (Follicular cells) D- Colloid (Thyroglobulin) * Function : 1- C-cell : Produces calcitonin and catecholamines. 2- Follicular cells : Secretion of T3 & T4 * Histopathological Lesion : 1- Thyroid adenoma. 2- Hashimoto thyroiditis. Interfollicular cells C-cell Thyrocyte
  • 7.
  • 8. 4- Parathyroid Gland * Component & Characteristics : 1- Thin capsule. 2- Chief (Principal) cells : - Parathyroid hormone (PTH). 3- Oxyphil cells (acidophilic) : - Degenerated chief cells. - Some Parathyroid hormone (PTH). 4- Colloid (homogeneous gel). 5- Blood vessel. * Function : - Regulation of Ca in blood (hypercalcemic). * Histopathological Lesion : - Parathyroid adenoma. Thin capsule of parathyroid gland