Needle stick and sharps injuries pose risks to healthcare workers. Sharps include needles as well as other objects that can cut or pierce skin. To prevent injuries, unsafe practices like recapping needles should be avoided. Anyone handling sharps is at risk, and nursing staff are most commonly injured. If exposed, proper first aid and reporting is important. Post-exposure prophylaxis based on exposure type and source status can reduce risk of infection from HIV, HBV, and HCV. Follow-up testing allows monitoring for potential seroconversion. Consistent use of safety devices, safe handling and disposal of sharps can help reduce healthcare worker injuries and exposures.
Needle stick injury and hazards of needle stickNCRIMS, Meerut
Needlestick injuries are wounds caused by sharps that accidentally puncture the skin.
Needlestick injuries are a hazard for people who work with hypodermic syringes and other needle equipment.
These injuries can occur at any time when people use, disassemble, or dispose of needles.
Sharp injuries and needle stick post exposure prophylaxis [compatibility mode]drnahla
Infection Control Guidelines for Sharp injuries and needle stick post exposure prophylaxis
Dr. NAHLA ABDEL KADERوMD, PhD.
INFECTION CONTROL CONSULTANT, MOH
INFECTION CONTROL CBAHI SURVEYOR
Infection Control Director, KKH.
Overview
Introduction to Needle Stick Injury(NSI)
Definition and History
Organisms transmitted due to NSI
Cause of Injury
Preventing Occupational injuries
Management of Exposed person
Data from AIIMS
Burden of NSI related diseases
Changing trend of NSI related disease
What can be done?
Summary
Blood spillage may occur because a laboratory sample breaks in the phlebotomy area or during transportation, or because there is excessive bleeding during
Needle stick injury and hazards of needle stickNCRIMS, Meerut
Needlestick injuries are wounds caused by sharps that accidentally puncture the skin.
Needlestick injuries are a hazard for people who work with hypodermic syringes and other needle equipment.
These injuries can occur at any time when people use, disassemble, or dispose of needles.
Sharp injuries and needle stick post exposure prophylaxis [compatibility mode]drnahla
Infection Control Guidelines for Sharp injuries and needle stick post exposure prophylaxis
Dr. NAHLA ABDEL KADERوMD, PhD.
INFECTION CONTROL CONSULTANT, MOH
INFECTION CONTROL CBAHI SURVEYOR
Infection Control Director, KKH.
Overview
Introduction to Needle Stick Injury(NSI)
Definition and History
Organisms transmitted due to NSI
Cause of Injury
Preventing Occupational injuries
Management of Exposed person
Data from AIIMS
Burden of NSI related diseases
Changing trend of NSI related disease
What can be done?
Summary
Blood spillage may occur because a laboratory sample breaks in the phlebotomy area or during transportation, or because there is excessive bleeding during
Needle stick injury (NSI) has a serious risk of transmission of various blood...lokendraicn
Needle stick injury (NSI) has a serious risk of transmission of various blood borne pathogens amongst healthcare personnel and more so in anaesthesiologists.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
NVBDCP.pptx Nation vector borne disease control program
Needle stick sharps injury and its post exposure prophylaxis management
1. Needle stick / Sharps injury and
its Post Exposure Prophylaxis /
Management
2. What are sharp?
A sharp is an object having an edge or point that is able to cut or
pierce the skin.
Sharp include needles as well as items such as scalpels , lancet,
razor, blade,scissors,
metal wire, retractor,
clamps,pins,. Staples,cutter
and glass items.
4. SHARP INJURY
Sharp Injuries are accidental cuts, punctures, nicks
and scratches to the healthcare personnel caused by
used sharp objects.
5. NEEDLE STICK INJURY
Needle stick Injury is defined as a cutaneus cut, scratch or
puncture from a needle that was contaminated with patients blood
or body fluid, whether or not the injury drew blood. It is an
accidental injury caused by used needles.
6. Who are at risk ?
Any worker handling sharp devices or equipment such as scalpels
, sutures, hypodermic needles, blood collection devices, or
phlebotomy devices is at risk
Nursing staff are most frequently injured
What can be cause?
Unsafe work practice( recapping, removal of phlebotomy tube
holder
Failure to dispose properly
Disposal system failures (overfull containers, needles sticking out
of container or piercing sides)
7. Risk of seroconversion due to sharps
injury from a known positive source
Virus Risk (Range)
HBV 6-30%
HCV ~2%
HIV 0.3%
8. PREVENTION OF NEEDLE STICK INJURY:
The "One-Hand" technique of recapping
needles. THE RIGHT WAY TO RECAP
Recapping with both hands.
NOTE: THIS IS DANGEROUS
Needles should not be recaped.
Use “ONE HAND” technique
9. Step 1
Place the cap on a flat surface, then
your hand from the cap.
Step 2
With one hand, hold the syringe
and use the needle to "scoop up"
the cap.
Step 3
When the cap covers the needle
completely; use the other hand to secure
the cap on the needle hub. Be careful to
handle the cap at the bottom only (near
the hub).
10. Newer Technologies for Safer Injections
Auto Disable (AD) and Re Use Prevention (RUP) Syringes
Prefilled Injection Devices:
Safety Syringes :
Vacuum Based Technology
Safety Needles and Cannulas
11. Needle-based safety injection device
27G Hypo Needle BD Eclipse™ Safety- needle in these syringes is
locked through a luer lock mechanism
12. 2. Never pass a sharp instrument from one
hand to another person’s hand directly: use
hand free technique
Example: Pass instrument in the kidney tray
14. Disposal of sharp
Collect sharp items in puncture proof containers.
Transport securely to disposal place.
Burn in high temperature incinerator or decontaminate and bury in
safe place.
15. Post-exposure prophylaxis(PEP)
Post-exposure prophylaxis(PEP) is any prophylactic
treatment started immediately after exposure to a
pathogen in blood or body fluids
Post Exposure Prophylaxis Guidelines
Immediate first aid
Report incident
Risk assessment
Counselling
Decision regarding use of PEP
Follow-up
16. Do Don’t
Remove gloves, if appropriate Do not panic
Wash the exposed site thoroughly
with running water
Do not put pricked finger in mouth
Irrigate with water or saline if eyes or
mouth have been exposed
Do not squeeze wound to bleed it
Wash the skin with soap and water Do not use bleach, chlorine,
alcohol, betadine, iodine or any
antiseptic or detergent
Note: Do consult the designated physician immediately as per hospital guidelines
for management of the occupational exposure. Report all needle stick injuries to
unit head / casualty medical officer. Fill the requisite proforma (NSI Form) and
send blood sample to microbiology laboratory for testing of HIV / HBsAg / HCV
after pre-test counseling and consent of both patient and health care worker.
17. Post-HIV exposure management/ prophylaxis
(PEP)
It is necessary to determine the status of the exposure and the
HIV/HBsAg/HCV status of the exposure source before starting post-
exposure prophylaxis(PEP)
Immediate measures:
• wash with soap and water
• No added advantage with antiseptic/bleach
Next step:
• Prompt reporting in accident/incident reporting forms
• Post-exposure treatment is begin as soon as possible
• Preferably within two hours
• Not recommended after seventy -two hours
• Late PEP? May be yes
Is PEP needed for all types of exposures? No
18. For HIV: Categories of exposure
Category
(Exposure code)
Definition & examples
Mild exposure
(EC1)
Mucous membrane/non-intact skin with small volumes
Eg: a superficial wound with a plain or low caliber needle,
Or contact with the eyes or mucous membranes, subcutaneous
injections following small-bore needles
Moderate exposure
(EC2)
Mucous membrane/non intact skin with large volumes or
percutaneous Superficial exposure with solid needle
Eg: a cut or needle stick injury penetrating gloves
Severe exposure
(EC3)
Percutaneous with large volume. Eg:
An accident with a high caliber needle (>18G)visibly
contaminated with blood;
A deep wound(haemorrhagic wound and/or very painful);
Transmission of a significant volume of blood;
An accident with material that has previously been used
intravenously or intraarterially.
19. Categories of situations depending on results of the source
Source HIV
Status/Code
Definition of risk in source
HIV negative Source is not HIV infected but consider HBV & HCV
Low risk (SC1) HIV positive & clinically asymptomatic
High risk (SC2) HIV positive & clinically symptomatic
Unknown Status of the patient is unknown & neither the patient
nor his/her blood is available for testing. The risk
assessment will be based only upon the exposure
20. Determine Post-Exposure
Prophylaxis(PEP) Recommendation
EC HIV SC PEP
1 1 Consider basic
1 2 Recommend basic regimen
2 1 Recommended expanded regimen
3 1 OR 2 Recommended expanded regimen
1,2,3 UNKNOWN If exposure setting suggests risks of HIV
Exposure, consider basic regimen
Basic regimen (Two Drug Regimen):
•Zidubudine 300 mg + Lamovudine 300 mg twice daily for 28 days.
•Expanded regimen: (Three drug regimen)
• Basic regimen (+ Indinavir – 800 mg/thrice a day, or any other protease Inhibitor.
21. Testing and Counseling
The health care provider are tested for HIV as per the following
schedule) to monitor seroconversion.
Base-line HIV test - at time of exposure
Repeat HIV test - at six weeks following exposure
2nd repeat HIV test - at twelve weeks following exposure
3rd repeat HIV test - at 6 months following exposure
22. Pregnancy and PEP:
Based on limited information, anti-retroviral therapy taken during
2nd and 3rd trimester of pregnancy has not caused serious side
effects in mothers or infants.
There is very little information on the safety in the 1st trimester. If
the HCW is pregnant at the time of exposure to HIV, the designated
authority/physician must be consulted about the use of the drugs
for PEP.
Side-effects of these drugs:
Most of the drugs used for PEP have usually been tolerated well
except for nausea, vomiting, tiredness, or headache.
24. Role of vaccine
Hepatitis B Vaccination
A primary course of hepatitis B vaccinations over six
months
Mandatory for all staff in contact with patients and patient-
contaminated material
Titre level (HBsAb) four to six weeks after last dose
Booster doses not required if titre level >10
mIU/mL
25. Recommended PEP for exposure to Hep C virus
Known Hepatitis C
NO ACTIVE PROPHYLAXIS AVAILABLE
Check hepatitis C virus RNA testing at 6 and 12 weeks
Check HCV antibody ( anti HCV ) at 12 and 24 weeks
Source known not to be infected with hepatitis C following testing at
time of incident
Check serum if symptoms or signs of liver disease develop
Hepatitis C status of source unknown
A risk assessment should be done
High risk – Manage as known infected source
Low risk – Obtain serum for anti HCV testing at 24 weeks
HCW found to be acquired hepatitis C infection following occupational
exposure should be referred immediately to a specialist in infectious
disease / physician for treatment.
26. FOLLOW UP SEROLOGY TESTING OF THE
EMPLOYEE TO BE DONE AS PER FOLLOWING
SCHEDULE:
1. HIV - 0,6 WEEKS, 12 WEEKS, 6 MONTHS
2. HbsAg - 0,6 WEEKS, 6 MONTHS
3. ANTI HCV - 0,(4-6) MONTHS
27. Laboratory test on follow up
Recommended follow up laboratory tests
Timing In persons taking
PEP
In persons not taking
PEP
Weeks 2 & 4 Transaminases
Complete blood count
Clinical monitoring for
hepatitis
Week 6 HIV Ab HIV Ab
Month 3 HIV Ab, anti HCV,
HBsAg
Transaminases
HIV Ab, anti HCV,
HbsAg
Month 6 HIV Ab, anti HCV,
HBsAg
Transaminases
HIV Ab, anti HCV,
HbsAg
28. Be Needle Smart
o Do NOT recap
o Do NOT bend
o Do NOT remove
o Do NOT transport
o Do NOT re –use
o Recap only when necessary.
o Report needle stick injury.
o Use puncture proof and leak proof
containers to discard needles.
o Do not fill the container more than 3/4th.
o Do not leave needle protruding from
containers.