This document discusses the need for analog mixed-signal (AMS) simulation in verifying mixed-signal IP cores. It notes that AMS simulation is needed to properly verify both the analog and digital parts, as they are interdependent. Challenges in AMS simulation include randomizing electrical signals and having basic knowledge of AMS to set voltage domains and dump waveforms. AMS simulation found issues like an analog watchdog detecting incorrect values and an ADC calibration sequence error.