It's fun to learn MUSCULAR SYSTEM...
This is primarily a synthesis of the topic including the different types of Muscular System, their movement, functions, sample practical exercises, categories on how muscles got its names, examples of diseases and its causes and effects, and a fun trivia to motivate the class...
Enjoy! God bless you all :)
Locomotion is movement of an organism from one place to another while movements can be performed at any particular space also. Bending of limbs, peristaltic movements, blinking of eye lids etc are some examples of movements. Locomotion is related with movements. Together, our bones, muscles, and joints - along with tendons, ligaments, and cartilage - form our musculoskeletal system and enable us to do everyday physical activities.
In this lesson you will learn about :
1) Functions of Human Skeleton
2) Parts of Skeletal System
3) Bone - Composition, Structure, Classification
4) The Human Skeleton
5) Joints
6) Lever Mechanism
I hope this document is helpful to you. Please share the document with your friends if you think this will benefit them. Get ready for the next lesson. Thanks.
It's fun to learn MUSCULAR SYSTEM...
This is primarily a synthesis of the topic including the different types of Muscular System, their movement, functions, sample practical exercises, categories on how muscles got its names, examples of diseases and its causes and effects, and a fun trivia to motivate the class...
Enjoy! God bless you all :)
Locomotion is movement of an organism from one place to another while movements can be performed at any particular space also. Bending of limbs, peristaltic movements, blinking of eye lids etc are some examples of movements. Locomotion is related with movements. Together, our bones, muscles, and joints - along with tendons, ligaments, and cartilage - form our musculoskeletal system and enable us to do everyday physical activities.
In this lesson you will learn about :
1) Functions of Human Skeleton
2) Parts of Skeletal System
3) Bone - Composition, Structure, Classification
4) The Human Skeleton
5) Joints
6) Lever Mechanism
I hope this document is helpful to you. Please share the document with your friends if you think this will benefit them. Get ready for the next lesson. Thanks.
MOVEMENT OF BONES OF AXIAL AND APPENDICULAR SYSTEM.pptxTaniyaMondal6
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You can find here about the Movements of Bones of Axial and Appendicular System, Range of Motion, Bones, Joint Movements in Anatomy and Physiology with the help of 3D live images for better understanding and knowledge purpose. This presentation is made considering the new medical and nursing students. explained in an easy wasy. so that you can learn some effective knowledge through this slides.
The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. The bone mass in the skeleton makes up about 14% of the total body weight and reaches maximum density around age 21
In my presentation, I have described about the anatomy and physiology of bone and also did a elaboration on the pathways which is responsible for bone cells formation. For more details related to bone you can contact me on my email : sheershopramanik24@gmail.com
it's about the skeletal system and the types of joint
in this slide show, I have told about the axial and appendicular skeleton and the six types of synovial joints like ball and socket joint, saddle joint, hinge joint, pivot joint, gliding joint and the condyloid joint.
MOVEMENT OF BONES OF AXIAL AND APPENDICULAR SYSTEM.pptxTaniyaMondal6
Â
You can find here about the Movements of Bones of Axial and Appendicular System, Range of Motion, Bones, Joint Movements in Anatomy and Physiology with the help of 3D live images for better understanding and knowledge purpose. This presentation is made considering the new medical and nursing students. explained in an easy wasy. so that you can learn some effective knowledge through this slides.
The human skeleton is the internal framework of the human body. It is composed of around 270 bones at birth – this total decreases to around 206 bones by adulthood after some bones get fused together. The bone mass in the skeleton makes up about 14% of the total body weight and reaches maximum density around age 21
In my presentation, I have described about the anatomy and physiology of bone and also did a elaboration on the pathways which is responsible for bone cells formation. For more details related to bone you can contact me on my email : sheershopramanik24@gmail.com
it's about the skeletal system and the types of joint
in this slide show, I have told about the axial and appendicular skeleton and the six types of synovial joints like ball and socket joint, saddle joint, hinge joint, pivot joint, gliding joint and the condyloid joint.
Moving and growing (grade 4) ( Science ) tehminaabrar
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A Power Point Presentation for class IV students for better comprehension of the topic- Moving and Growing ( Science)
I hope it was helpful. For more Presentations Like, Share and Comment.
The muscular system is a complex network of tissues and organs responsible for movement, stability, and heat generation in the human body. Comprising more than 600 individual muscles, it enables various functions, including locomotion, posture maintenance, breathing, and circulation assistance. Muscles are composed of muscle fibers, which are elongated cells capable of contracting and relaxing to generate force. Skeletal muscles, attached to bones via tendons, facilitate voluntary movements, such as walking and lifting objects, under conscious control. Smooth muscles, found in organs like the digestive tract and blood vessels, perform involuntary functions like peristalsis and regulating blood flow. Cardiac muscle, exclusively present in the heart, sustains its rhythmic contractions to pump blood throughout the body. The muscular system works in coordination with the skeletal, nervous, and circulatory systems to ensure efficient movement and overall bodily function. Regular exercise and proper nutrition are essential for maintaining muscular health and strength throughout life.
For more such informative content, go to https://scifitechify.blogspot.com/.
This presentation is about a biology topic. It talks about the skeletal and nervous system. It tasks about their structures and different parts involved in the structure. It is a really informative presentation.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
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As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
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Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other  chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released. Â
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules -Â a chemical called pyruvate. A small amount of ATP is formed during this process.Â
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP.  Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.Â
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.Â
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : Â cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's entangled aventures in wonderlandRichard Gill
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Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
The increased availability of biomedical data, particularly in the public domain, offers the opportunity to better understand human health and to develop effective therapeutics for a wide range of unmet medical needs. However, data scientists remain stymied by the fact that data remain hard to find and to productively reuse because data and their metadata i) are wholly inaccessible, ii) are in non-standard or incompatible representations, iii) do not conform to community standards, and iv) have unclear or highly restricted terms and conditions that preclude legitimate reuse. These limitations require a rethink on data can be made machine and AI-ready - the key motivation behind the FAIR Guiding Principles. Concurrently, while recent efforts have explored the use of deep learning to fuse disparate data into predictive models for a wide range of biomedical applications, these models often fail even when the correct answer is already known, and fail to explain individual predictions in terms that data scientists can appreciate. These limitations suggest that new methods to produce practical artificial intelligence are still needed.
In this talk, I will discuss our work in (1) building an integrative knowledge infrastructure to prepare FAIR and "AI-ready" data and services along with (2) neurosymbolic AI methods to improve the quality of predictions and to generate plausible explanations. Attention is given to standards, platforms, and methods to wrangle knowledge into simple, but effective semantic and latent representations, and to make these available into standards-compliant and discoverable interfaces that can be used in model building, validation, and explanation. Our work, and those of others in the field, creates a baseline for building trustworthy and easy to deploy AI models in biomedicine.
Bio
Dr. Michel Dumontier is the Distinguished Professor of Data Science at Maastricht University, founder and executive director of the Institute of Data Science, and co-founder of the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. His research explores socio-technological approaches for responsible discovery science, which includes collaborative multi-modal knowledge graphs, privacy-preserving distributed data mining, and AI methods for drug discovery and personalized medicine. His work is supported through the Dutch National Research Agenda, the Netherlands Organisation for Scientific Research, Horizon Europe, the European Open Science Cloud, the US National Institutes of Health, and a Marie-Curie Innovative Training Network. He is the editor-in-chief for the journal Data Science and is internationally recognized for his contributions in bioinformatics, biomedical informatics, and semantic technologies including ontologies and linked data.
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
6. BICEPS
• The large, two-headed
muscle at the front of the
upper arm.
• The most familiar muscle
of the upper limb.
• Enables us to move our
forearm towards our
shulder.
8. DELTOID
• The large, triangular
muscles in our shoulders.
• Enables us to swing and
rotate our arms.
• These muscles are fleshy,
which make these muscles a
good site for injections and
vaccines.
11. MUSCLES
IN OUR
BACK
• Enables us to extend our back and keep our body
erect.
• They also function when we swim or strike a blow.
12. LOWER
LIMB
MUSCLES
• Allows us to move
our hips, legs, knees,
and joints in our
feet.
• They include
the strongest, and
largest muscles in
our body.
• They support and
balance the body.
13. GLUTEUS
• The largest muscles found
in our hips and buttocks.
• They work when we jump
or climb stairs.
• They keep our hips steady
when we walk.
• They are also good
injection sites.
14. QUADRICEP
S
• The muscles in our thighs
• Allows us to flex our legs
and bend our knees.
• We can do
these movements because o
ur quadriceps muscles and
our leg muscles work
together.
16. HOW MUSCLES WORK
• Most muscles work in parts. As one muscle contracts, the
other muscle reflexes. For example, as we move our elbow,
our biceps contract. Our triceps, reflexes in turn.
17. VOLUNTAR
Y
MUSCLES
• They only move when you intend
to move them.
• These are the muscles that
cover our skeleton.
• Tendons attach these muscles
to the bones.
• Helps us perform different
movements such as running ,
dancing, and jumping.
18. INVOLUNTARY
MUSCLES
• Muscles that cannot be
controlled and move on their
own.
• They include the muscles in the
heart and other internal organs.
• They perform involuntary body
activities, including those
that proceed even while you are
asleep, like digesting
food, pumping blood, and
breathing.
20. CARDIAC
MUSCLES
• These are involuntary muscles that
are made up of striped or striated
muscles.
• They contract involuntary and
regularly to help the
heart pump blood throughout the
body.
21. SMOOTH
MUSCLES
• Involuntary muscles that are mainly
found in the walls of hollow internal
organs, such as blood vessels,
intestines, and glands.
• They are non-striated and
spindle shaped, or wide in the
middle and narrow at each end.
• They perform involuntary
activities and aid in the digestion of
food and the exhange of gases in
the lungs.
22. SKELETAL MUSCLES
• Muscles that are attached to the bones of the
skeleton.
• Made up of many cylindrical fibers with a
striated appearance.
• Involved in voluntary movements, such as
movements of the arms, as well
as running, dancing, jumping and walking.
• Biceps and Triceps are examples
of Skeletal Muscles because they help us
move our arms.
23. Bones,
Muscles,
and
Brain
Work
Together
The brain directs all the activities of the
body such as the blinking of the eyes, the
pumping of blood by the heart, the
digestion of food by the stomach, and the
respiration of the lungs.
The interaction of the functions of the
brain, bones, and muscles can also be
observed in other common circumstances.
For example, you accidentally step on a
pointed nail, the message is sent to the
brain, which automatically prompts the
bones and muscles to respond. You feel the
pain and then you wiggle your foot to ease
that pain.
