In India 35% of total energy being consumed for buildings and it is growing 8% annually. The growing energy demand for buildings leads from traditional biomass to commercial fuels, this results in increasing carbon emissions and aggravates power shortages in India. Fenestration system are the largest elements for energy loss in buildings. Accurate and exact evaluation of transfer performance is critical in determining overall use of energy in building. Hence, two dimensional (2-D) heat transfer analysis transfer can be used to determine thermal performance as three dimensional (3-D) may be complex one as compared to 2-D. All two dimensional results can be analyzed using WINDOW and THERM software while, practical experiment can be analyzed using hot box method but it is too expensive for each product. Results were obtained for broad range of products in market with frame materials, spacers, insulated glass units (IGU). All 2-D results were obtained with THERM6/WINDOW6. All three modes of heat transfer mechanism were incorporated in heat transfer modeling. For energy transfer we have to determine U factor i.e. heat transfer coefficient which tells about heat transfer Results shows that different material had great impact on the performance of heat transfer while, the spacer systems did not have much impact on the 2-D results as it only focus on reducing moisture content of building fenestration and prevent from mold development. It can be concluded that if we concentrate on different material and varies boundary conditions we get different results which can be great help in reducing global warming and heat transfer that is contrast reducing energy loss