Scientists have discovered new ways to trap and kill the malaria parasite. Researchers found that blocking the pore through which the parasite communicates with the outside of red blood cells fatally imprisons the parasite, preventing it from stealing resources and eliminating waste. Separate research identified a protein that guides folding and unfolding of parasite proteins, and blocking this protein could prevent transmission through the pore. Stem cell scientists have also developed a method to track gene expression in specific cell types in the kidneys of rats to better understand acute kidney injury and identify early signs of damage.

1. SCIENTISTS FIND WAY TO
TRAP, KILL MALARIA
PARASITE AND STEM CELL
SCIENTISTS LAY TRAP FOR
DISEASE.
Daniela Alarcón Bolívar
Medicine students
3rd semester
U.P.B
2014

4. INTRODUCTION
Nowadaysthemolecular biology is
very important asdifferent
investigationscould understand how
different organismsaffect humans.
Also through experimentation in rats
it hasbeen thought that in thefuture
might find moreand better solutions
for diseasessuch asrenal failure.
All thisfor very small thingsbut way
too important asDNA.

5. SCIENTISTS FIND WAY TO
TRAP, KILL MALARIA
PARASITE
Malaria is a disease caused by the parasite
plasmodium falciparum, thisparasiteistransmitted
by the Anopheles mosquito, he infected itches
transmitting disease to the people. It can be
transmitted in a placental or blood transfusions.
Malaria causes about 627,000 deaths in a year in
thetropics.
Date: July 16, 2014
Source: Washington University in St. Louis

6. SCIENTISTS FIND WAY TO TRAP,
KILL MALARIA PARASITE
• In order to live and reproduce the parasite invades red blood
cells, taking part of their membrane to create a compartment,
turning the red blood cells in your home, this is done by
segregating different proteins.
• The parasite proteins are ejected by a single pore to the red
blood cell. The Parasite proteins are different to those
produced by thehuman being

7. SCIENTISTS FIND WAY TO TRAP,
KILL MALARIA PARASITE
Different studies seek to terminate a step in the growth of
the parasite that causes malaria. New research has found
that to kill malaria Parasite have to closetheporethrough
which it communicateswith theoutside.
Different studies seek to terminate a step in the growth of
the parasite that causes malaria. New research has found
that to kill malaria Parasite have to close the pore through
which it communicateswith theoutside.
It is believed that by blocking the pore, the parasite is
fatally imprisoned, unable to steal resources from the red
blood cell or eliminating waste.
It is believed that by blocking the pore, the parasite is
fatally imprisoned, unable to steal resources from the red
blood cell or eliminating waste.

8. SCIENTISTS FIND WAY TO TRAP,
KILL MALARIA PARASITE
A different research, studying a
protein "thermal shock" HSP 101,
so named because it acts when the
cell is heated. The HSP 101 has
different functions as guide the
folding and unfolding of proteins
of the parasite that causes malaria,
may also condition them for
spending for the pore a in a linear
manner and provide part of the
energy necessary to pass through
thepore.
By blocking this protein,
translocation can be prevented,
among other things.

9. SCIENTISTS FIND WAY TO TRAP,
KILL MALARIA PARASITE
Malaria is a disease that
affects millions of vulnerable
people in the world, I find it
necessary to seek different
treatment alternatives to
prevent many deaths and
improvethequality of lifefor
all people.
Similarly, the different
mutations of organisms,
creates drug resistance,
necessitating the invention of
new drugs.

10. STEM CELL SCIENTISTS
LAY TRAP FOR
DISEASE
Date: July 11, 2014
Source: University of Southern California- Health Sciences
Stem cells differ from other cells by
several features. Ability to divide to
produce new stem cells and their ability to
generate mature specialized cells, under
certain physiological conditions.

11. STEM CELL SCIENTISTS
LAY TRAP FOR DISEASE
STEM CELL SCIENTISTS
LAY TRAP FOR DISEASE
Acute renal failure is the rapid loss (about 2 days) the
ability of the kidneys to remove waste and maintain fluid
balanceand electrolytes.
Acute renal failure is the rapid loss (about 2 days) the
ability of the kidneys to remove waste and maintain fluid
balanceand electrolytes.
Acute renal failure may occur as a result of surgery,
infection or drug toxicity for different treatments. This
can lead to chronic kidney damageor death.
Acute renal failure may occur as a result of surgery,
infection or drug toxicity for different treatments. This
can lead to chronic kidney damageor death.

12. STEM CELL SCIENTISTS LAY
TRAP FOR DISEASE
• Scientists at the Rockefeller Institute for Medical Research in
2008, invented a fluorescent marker for any cell ribosomes, TRAP
(means"translating ribosomeaffinity purification.").
• With this they can determine which genes assets, ordered the
production of proteinsfrom ribosomes.
• Other researchers applied this technique in transgenic mice to take
cellular and genetic information of different organs, including the
kidney.

13. STEM CELL SCIENTISTS LAY
TRAP FOR DISEASE
Some researchers used rats
to identify four types of
renal cells and identify early
signs of acute kidney injury.
Early detection of renal
damage, could improve the
health of patients, would
allow other molecularly
understand various diseases
and functioning of organs to
injury.

14. STEM CELL SCIENTISTS LAY
TRAP FOR DISEASE
• I think this kind of research can have good
results, not only to understand the operation
of various diseases, their progression and
complications, but also to find new forms of
treatment.
• Always looking to
improve the quality of life
of patients.

15. MEDICAL UTILITY
Nowadays the molecular biology is
being heavily used to find answers to
crucial processes in the health of
people.
I think it is of great medical use to
find new ways to treat diseases that
evolve every day and become more
difficult to combat.
Nowadays the molecular biology is
being heavily used to find answers to
crucial processes in the health of
people.
I think it is of great medical use to
find new ways to treat diseases that
evolve every day and become more
difficult to combat.

16. MEDICAL UTILITY
The medicine must keep
pace technologically or
even faster with society,
should always seek the
welfare of people suffer
every day from various
conditions. As is the case
of malaria, although
Africa is the place where
most often, in the
Colombian jungles there
are also a large number of
people who die from this
disease.

17. MEDICAL
UTILITY
• Prevention isan important part of medicine, so I think it's
necessary to makestudiesto determinethedamage, without
causing this, everything to ensuretheeffectivenessof the
treatment to which thepatient undergoes. In acutekidney
diseasemay not know thedamagethat isgenerated until after
thisisdone, if known earlier could prevent many deaths.

18. MEDICAL UTILITY
Technology should be a tool for the physician should
understand and use it in the best way for the welfare of
the patient. We need further research to have better
argumentsto fight disease.
Experiments with rats have been used for many years
for answers in humans, it has made ​​great progress and
can even more.
Technology should be a tool for the physician should
understand and use it in the best way for the welfare of
the patient. We need further research to have better
argumentsto fight disease.
Experiments with rats have been used for many years
for answers in humans, it has made ​​great progress and
can even more.

19. REFERENCES
• SCIENCE DAILY. Scientistsfind way to trap, kill malaria
parasite.
http://www.sciencedaily.com/releases/2014/07/140716131543.ht
m. [Consult july 18]
• SCIENCE DAILY. Stem cell scientistslay TRAPfor disease.
http://www.sciencedaily.com/releases/2014/07/140711153337.ht
m. [Consult july 18]
• HEALTHINNOVATIONS. Scientistsfind way to trap, kill
malaria parasite. http://health-
innovations.org/2014/07/17/scientists-find-way-to-trap-kill-
malaria-parasite/ [Consult july 18]
• LÓPEZ GUERRERO, JoséAntonio. CélulasMadre: lamadrede
todaslascélulas. 1ª.ed. Madrid: Helice,2003. 63 p.

20. THANK
YOU VERY
MUCH.