Mitochondria contain their own circular genome that is 16.5kb in size and located in the mitochondrial matrix. The mitochondrial genome contains 37 genes that encode 13 proteins, 22 tRNAs, and 2 rRNAs. These genes help produce enzymes and proteins that are crucial for oxidative phosphorylation and energy production in mitochondria. The control region of mitochondrial DNA contains signals that regulate mitochondrial DNA and RNA synthesis.