Minamata disease was caused by mercury poisoning from industrial wastewater discharged into Minamata Bay in Kumamoto, Japan by Chisso Corporation from 1932 to 1968. Over 17,000 victims suffered symptoms including numbness, hearing and vision loss, and even death. While remediation efforts cleaned the bay, many victims still experience health issues. The disaster demonstrated the importance of responsible waste disposal and protecting the environment and human health from industrial pollution.
Minamata is a city located in the Kumamoto prefecture, Japan. The Chisso Corporation, basically a fertilizer and chemicals producer started to release its waste into the Minamata river. This affected the whole Minamata community since the concentration Mercury became high.
The document discusses the Minamata mercury pollution incident that occurred in Japan between 1908 and 1959. It summarizes that:
1) A chemical factory began dumping mercury-laced wastewater into Minamata Bay in 1908, poisoning the local fishing community through the food chain over decades.
2) "Minamata disease" was discovered and linked to methylmercury poisoning in 1956 when residents developed neurological symptoms.
3) It took until 1959 to officially identify the factory as the source of pollution and order wastewater treatment, by which time many had died or suffered permanent injury from mercury exposure.
From 1932 to 1968, the Chisso Corporation dumped approximately 27 tons of mercury compounds into Minamata Bay from its chemical factory in Kumamoto, Japan. The mercury bioaccumulated in the local seafood which, when eaten by the local population, caused thousands to develop mercury poisoning symptoms known as Minamata disease. Symptoms included neurological problems like numbness, impaired vision and speech. It was later discovered that the mercury compounds were a byproduct of the factory's production process. Despite early warnings, the Chisso Corporation denied claims and continued polluting until 1959 when researchers conclusively linked the disease to methylmercury poisoning from the factory's waste.
Minamata disease is a nervous system disorder caused by eating fish and shellfish contaminated with methyl mercury, a byproduct discharged from acetaldehyde factories into the water. In Minamata, many people contracted the disease in the 1950s after eating large amounts of contaminated seafood. Since then, the city has worked to regenerate by issuing declarations to improve the environment, health and welfare through garbage sorting, recycling, and eco-friendly shops to prevent future pollution.
Environmental Engineering - Case Study - The Minamata Disease DisasterJohn Paul Espino
The Minamata Bay pollution disaster in Japan from 1932 to 1968 exposed local residents to methylmercury released as a byproduct of a chemical plant. Over time, residents developed neurological symptoms and the cause was traced to eating fish and shellfish contaminated with mercury from the plant's wastewater. While the company denied responsibility, over 2,000 victims were eventually certified with more receiving compensation. Decades later, protests and media coverage helped bring awareness and democratization around the environmental and human impacts of industrial pollution.
Mercury poisoning
History of occurrence of Minamata disease
Signs and symptoms of Minamata disease
Treatment of Minamata
Chisso Corporation’s chemical factory
A case study on minamata disease-By Ritu Chauhanabhimicro19
Minamata disease was caused by mercury poisoning from industrial wastewater dumped into Minamata Bay from 1956-1968. Over 900 people died and thousands suffered from neurological symptoms like numbness, weakness, and loss of coordination. The disease drew attention to environmental pollution issues in Japan. After the victims were recognized, Minamata City took measures like environmental education, promoting sustainable practices, and honoring those affected to prevent future disasters and rebuild their community.
Minamata Bay was heavily polluted in the 1950s and 1960s by wastewater from the Chisso Corporation's factory in Minamata, Japan, particularly by methylmercury. The highly toxic compound bioaccumulated in fish and shellfish in the bay which, when eaten by the local populace, caused Minamata disease. More than 10,000 people were affected, 1,784 of whom had died. While pollution and illnesses continued for decades, compensation to victims has occurred and clean-up efforts have been made, though the issue remains ongoing in Japanese society.
Minamata is a city located in the Kumamoto prefecture, Japan. The Chisso Corporation, basically a fertilizer and chemicals producer started to release its waste into the Minamata river. This affected the whole Minamata community since the concentration Mercury became high.
The document discusses the Minamata mercury pollution incident that occurred in Japan between 1908 and 1959. It summarizes that:
1) A chemical factory began dumping mercury-laced wastewater into Minamata Bay in 1908, poisoning the local fishing community through the food chain over decades.
2) "Minamata disease" was discovered and linked to methylmercury poisoning in 1956 when residents developed neurological symptoms.
3) It took until 1959 to officially identify the factory as the source of pollution and order wastewater treatment, by which time many had died or suffered permanent injury from mercury exposure.
From 1932 to 1968, the Chisso Corporation dumped approximately 27 tons of mercury compounds into Minamata Bay from its chemical factory in Kumamoto, Japan. The mercury bioaccumulated in the local seafood which, when eaten by the local population, caused thousands to develop mercury poisoning symptoms known as Minamata disease. Symptoms included neurological problems like numbness, impaired vision and speech. It was later discovered that the mercury compounds were a byproduct of the factory's production process. Despite early warnings, the Chisso Corporation denied claims and continued polluting until 1959 when researchers conclusively linked the disease to methylmercury poisoning from the factory's waste.
Minamata disease is a nervous system disorder caused by eating fish and shellfish contaminated with methyl mercury, a byproduct discharged from acetaldehyde factories into the water. In Minamata, many people contracted the disease in the 1950s after eating large amounts of contaminated seafood. Since then, the city has worked to regenerate by issuing declarations to improve the environment, health and welfare through garbage sorting, recycling, and eco-friendly shops to prevent future pollution.
Environmental Engineering - Case Study - The Minamata Disease DisasterJohn Paul Espino
The Minamata Bay pollution disaster in Japan from 1932 to 1968 exposed local residents to methylmercury released as a byproduct of a chemical plant. Over time, residents developed neurological symptoms and the cause was traced to eating fish and shellfish contaminated with mercury from the plant's wastewater. While the company denied responsibility, over 2,000 victims were eventually certified with more receiving compensation. Decades later, protests and media coverage helped bring awareness and democratization around the environmental and human impacts of industrial pollution.
Mercury poisoning
History of occurrence of Minamata disease
Signs and symptoms of Minamata disease
Treatment of Minamata
Chisso Corporation’s chemical factory
A case study on minamata disease-By Ritu Chauhanabhimicro19
Minamata disease was caused by mercury poisoning from industrial wastewater dumped into Minamata Bay from 1956-1968. Over 900 people died and thousands suffered from neurological symptoms like numbness, weakness, and loss of coordination. The disease drew attention to environmental pollution issues in Japan. After the victims were recognized, Minamata City took measures like environmental education, promoting sustainable practices, and honoring those affected to prevent future disasters and rebuild their community.
Minamata Bay was heavily polluted in the 1950s and 1960s by wastewater from the Chisso Corporation's factory in Minamata, Japan, particularly by methylmercury. The highly toxic compound bioaccumulated in fish and shellfish in the bay which, when eaten by the local populace, caused Minamata disease. More than 10,000 people were affected, 1,784 of whom had died. While pollution and illnesses continued for decades, compensation to victims has occurred and clean-up efforts have been made, though the issue remains ongoing in Japanese society.
The document provides a history of mercury use and discusses the Minamata Convention. It describes how mercury has been used as a pigment and medicine for thousands of years. It then summarizes the Minamata Bay mercury poisoning incident in Japan in the 1950s-60s caused by industrial pollution. The rest of the document outlines the key points of the Minamata Convention, including banning mercury in various products and processes by certain dates, with exceptions for some traditional uses. It also notes industry opposition in Japan to restrictions on mercury trade.
The Bhopal gas tragedy was the worst industrial disaster in history. In 1984, a leak of methyl isocyanate gas from a pesticide plant owned by Union Carbide in Bhopal, India exposed over 500,000 people to toxic gases. At least 3,787 people died due to the gas release and many more suffered severe, long-term health issues. The cause of the leak remains disputed between Union Carbide and the Indian government, with both sides blaming each other or sabotage. To this day, the site remains contaminated and people continue to suffer health problems from exposure to the gases.
Environmental toxicology is the study of harmful effects of chemicals, biological and physical agents on living organisms. Rachel Carson is considered the founder of environmental toxicology through her book Silent Spring which documented the effects of uncontrolled pesticide use. Some key sources of environmental toxicity include pollutants, heavy metals, pesticides, and hazardous wastes. Proper management and regulations of hazardous wastes are needed to reduce environmental and health risks.
The ozone hole was first discovered in 1985 by British physicist Joe Farman. It is caused by chlorofluorocarbons (CFCs) emitted from industries that react with ozone in the stratosphere. CFCs contain chlorine atoms that break down ozone molecules. The conditions in Antarctica, including its long winter darkness and polar stratospheric clouds, allow chlorine to accumulate and destroy large amounts of ozone each spring, depleting the ozone layer over Antarctica and forming the ozone hole.
Water pollution occurs when harmful substances are added to water bodies, affecting their quality. Some key causes of water pollution include domestic sewage, industrial and agricultural runoff containing chemicals, heavy metals, and excess nutrients. This can have severe health and environmental impacts such as killing millions of children annually from waterborne diseases, reducing oxygen levels in water, and accumulating in organisms up the food chain. Addressing water pollution requires improved waste management through various physical, chemical, and biological treatment methods to remove pollutants and conserve water resources for the growing population.
If the question is asked “What is Love Canal? Why is it important?” the answer could be simply put, it is an incomplete canal, or just a trench, built in western New York state in the 1890s. From the 1930s through the 1950s, it was used as a chemical waste dump. The surrounding land was then sold and used for residential purposes, and soon people began complaining about strange odours and possible health problems. Since the late 1970s, many studies have been done to ascertain whether any health problems can be traced to the waste dumped into LoveCanal.
It is significant because it was the first case concerning hazardous waste disposal and its possible health effects that received major national attention. The information in this site is drawn primarily from two publications: Monitoring the Community for Exposure and Disease, a report to the Agency for Toxic Substances and Disease Registry (Nicholas Ashford, Principal Investigator, and Linda Schierow, Project Manager, Centre for Technology, Policy and Industrial Development, 1991) and Love Canal: Science, Politics, and People (Adeline Gordon Levine, Toronto: D.C. Heath, 1982). Other information is drawn from materials listed in the other Love Canal Resources sections.
The Love Canal neighbourhood is located in the city of Niagara Falls, in western New York State. It officially covers 36 square blocks in the south-eastern corner of the city. Two bodies of water define the northern and southern boundaries of the neighbourhood Bergholtz Creek to the north and the Niagara River one-quarter mile to the south. Open fields are to the east, and the western border is 92nd Street. The canal itself is enclosed by 97th, 99th, Colvin and Frontier Streets.
Love Canal incident is remembered as a "national symbol of a failure to exercise a sense of concern for future generations", as retold by, New York State Health Department Commissioner David Axelrod.....it is an example of ground water pollution
The document discusses various topics related to air pollution including:
1) Definitions of air pollution and examples of early observations of air pollution.
2) Examples of major air pollution episodes from 1930 to 1984 that caused deaths.
3) Health effects of air pollution on respiratory, cardiovascular and other systems.
4) Environmental effects such as damage to ecosystems, property and quality of life.
5) Sources of air pollution including natural processes and man-made stationary, transportation, industrial and waste sources.
The Chisso Corporation dumped mercury waste into Minamata Bay from 1932 to 1968, poisoning the local fishing community and causing "Minamata Disease". Over 3,000 victims suffered physical deformities, brain damage, or death from methylmercury poisoning. It took decades for victims to receive compensation, as Chisso denied responsibility. By 1973, a court ruled Chisso was negligent in its dumping and liable for damages, though compensation continues nearly 50 years later.
Pesticides are chemicals designed to kill pests like weeds, insects, and fungi. They can cause acute poisoning, delayed illnesses, and allergic reactions in humans exposed through various means like ingestion, inhalation, eye or skin contact. Symptoms range from skin/eye irritation to excessive sweating or difficulty breathing. Exposure is prevented through proper storage, use of protective equipment, integrated pest management, and community education. First aid involves washing exposed areas, inducing vomiting only if instructed, and getting medical help. While pesticides boost agriculture, improper use without training harms both human and environmental health.
Biomagnification is the increasing concentration of a substance like pesticides in organisms at higher levels of the food chain. It occurs most often in higher trophic levels where exposure is through food rather than water. An example is DDT, an insecticide used from the 1940s to 1960s that entered the environment and biomagnified up the food chain, negatively impacting bald eagle populations. To control biomagnification, harmful substances should not be put in water systems, toxic pesticides should be avoided, organic foods eaten, and time spent in contaminated areas limited.
Thermal pollution is the increase in temperature of air, water, or land caused by human activity. It occurs when industries and power plants use nearby water sources to cool machinery and discharge warmer water back into lakes or streams, increasing their temperature over time. Other causes include urban sprawl which increases the amount of concrete absorbing heat, deforestation which removes shade-providing trees, and pollution particulates that trap heat. The effects of thermal pollution include decreased oxygen levels in water harming aquatic life, and wildlife populations being unable to adapt to rapid temperature changes.
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed and relocated in the environment as a result of the incomplete combustion of organic matter. Many PAHs and their epoxides are highly toxic, mutagenic and/or carcinogenic to microorganisms as well as to higher systems including humans. Although various physicochemical methods have been used to remove these compounds from our environment, they have many limitations.
Bioaccumulation and biomagnification refer to the increasing concentration of pollutants like pesticides, mercury, and other chemicals as they move up the food chain. Bioaccumulation is when an organism absorbs more of a substance than it eliminates, resulting in increasing concentration over time. Biomagnification occurs when concentrations increase at each trophic level, so organisms at the top of food chains face greater exposure. Pollutants like DDT, PCBs, and mercury are especially prone to bioaccumulation and biomagnification due to their persistence and ability to concentrate in fatty tissues. This can negatively impact wildlife and pose risks to human health through consumption of contaminated fish and seafood.
1) The document provides background information on the 1984 Bhopal gas tragedy in India, where a leak of methyl isocyanate gas from a Union Carbide pesticide plant killed thousands.
2) It describes the events leading up to the leak, including safety issues and cost-cutting measures at the plant.
3) Two theories for the cause of the leak are described - accidental water contamination during pipe cleaning, and sabotage by an employee.
4) The aftermath of the disaster is discussed, including health impacts, environmental contamination, legal issues, and policy changes implemented.
5) Lessons from Bhopal include the need for emergency planning, public information, and controlling industrial hazards near populations.
The document discusses water quality standards and issues in India. It notes that while India receives significant rainfall, it is unevenly distributed and water resources are overexploited, resulting in major water quality problems. The major sources of water pollution are domestic sewage (26,254 mld generated but only 6,955 mld treated), industrial wastewater (13,468 mld generated but only 60% treated), and agricultural runoff. This pollution contributes to issues like pathogenic contamination, eutrophication, and depletion of dissolved oxygen. National water quality monitoring tests for over 30 parameters to assess core water quality issues across India. Key water quality parameters that are discussed include pH, turbidity, hardness, TDS, and various
The Love Canal disaster involved a neighborhood in Niagara Falls, New York that was built on top of a former chemical waste dump containing over 21,000 tons of toxic waste. In the late 1970s, residents noticed high rates of cancer and birth defects, which were eventually traced to the chemical waste leaking into the soil and water supply from the dump located under the neighborhood. Over 800 families were evacuated and reimbursed for their homes after extensive legal battles and media coverage brought attention to the environmental and public health crisis.
This document discusses oil pollution, including its sources, effects, and control measures. It notes that oil pollution endangers aquatic life and coastal environments. Major sources include cargo tanker washing, oil spills during transport, bilge dumping, and accidents. Effects range from reduced oxygen in water, harm to marine ecosystems and wildlife, and human health impacts. Control methods encompass physical removal techniques like skimming, as well as chemical dispersion and biological degradation using microorganisms. The overall document aims to raise awareness about oil pollution and the need to protect ocean environments.
This document discusses various types of environmental toxicology and pollution. It notes that chemicals can have global impacts through long-range atmospheric transport and persist in the environment far from where they were used. Examples of specific issues covered include acid rain from air pollution damaging ecosystems, stratospheric ozone depletion from CFCs requiring international agreements like the Montreal Protocol, and global warming from fossil fuel emissions trapping heat via the greenhouse effect. The document stresses that environmental changes can ultimately expose humans through multiple routes, so comprehensive risk assessments are needed.
The document discusses several topics related to hazardous and toxic wastes:
1. Toxic materials used industrially can harm workers' health and hazardous wastes such as heavy metals and pesticides can cause health problems if improperly handled.
2. Minamata disease is a neurologic disorder caused by methyl mercury poisoning from industrial waste discharged into Minamata Bay in Japan. Mercury poisoning through fish consumption affected local communities.
3. The document provides details on ionizing radiation, which can damage cells and DNA, and non-ionizing radiation, which includes optical radiation and electromagnetic fields that can cause thermal or electrical harm in high doses.
The document discusses several topics related to hazardous and toxic wastes:
1) Toxic materials used industrially can harm workers' health. Hazardous wastes include toxic, reactive, radioactive, and infectious medical wastes which threaten human and environmental health if improperly handled.
2) Minamata disease is caused by methyl mercury poisoning from industrial wastewater discharged into Minamata Bay in Japan. Mercury contamination of fish through industrial waste entering waterways can poison humans through fish consumption.
3) The document provides 10 points on Minamata disease, covering what type of disease and substance caused it, patient numbers, the responsible company, impacts to the bay and patients, and lessons on environmental
The document provides a history of mercury use and discusses the Minamata Convention. It describes how mercury has been used as a pigment and medicine for thousands of years. It then summarizes the Minamata Bay mercury poisoning incident in Japan in the 1950s-60s caused by industrial pollution. The rest of the document outlines the key points of the Minamata Convention, including banning mercury in various products and processes by certain dates, with exceptions for some traditional uses. It also notes industry opposition in Japan to restrictions on mercury trade.
The Bhopal gas tragedy was the worst industrial disaster in history. In 1984, a leak of methyl isocyanate gas from a pesticide plant owned by Union Carbide in Bhopal, India exposed over 500,000 people to toxic gases. At least 3,787 people died due to the gas release and many more suffered severe, long-term health issues. The cause of the leak remains disputed between Union Carbide and the Indian government, with both sides blaming each other or sabotage. To this day, the site remains contaminated and people continue to suffer health problems from exposure to the gases.
Environmental toxicology is the study of harmful effects of chemicals, biological and physical agents on living organisms. Rachel Carson is considered the founder of environmental toxicology through her book Silent Spring which documented the effects of uncontrolled pesticide use. Some key sources of environmental toxicity include pollutants, heavy metals, pesticides, and hazardous wastes. Proper management and regulations of hazardous wastes are needed to reduce environmental and health risks.
The ozone hole was first discovered in 1985 by British physicist Joe Farman. It is caused by chlorofluorocarbons (CFCs) emitted from industries that react with ozone in the stratosphere. CFCs contain chlorine atoms that break down ozone molecules. The conditions in Antarctica, including its long winter darkness and polar stratospheric clouds, allow chlorine to accumulate and destroy large amounts of ozone each spring, depleting the ozone layer over Antarctica and forming the ozone hole.
Water pollution occurs when harmful substances are added to water bodies, affecting their quality. Some key causes of water pollution include domestic sewage, industrial and agricultural runoff containing chemicals, heavy metals, and excess nutrients. This can have severe health and environmental impacts such as killing millions of children annually from waterborne diseases, reducing oxygen levels in water, and accumulating in organisms up the food chain. Addressing water pollution requires improved waste management through various physical, chemical, and biological treatment methods to remove pollutants and conserve water resources for the growing population.
If the question is asked “What is Love Canal? Why is it important?” the answer could be simply put, it is an incomplete canal, or just a trench, built in western New York state in the 1890s. From the 1930s through the 1950s, it was used as a chemical waste dump. The surrounding land was then sold and used for residential purposes, and soon people began complaining about strange odours and possible health problems. Since the late 1970s, many studies have been done to ascertain whether any health problems can be traced to the waste dumped into LoveCanal.
It is significant because it was the first case concerning hazardous waste disposal and its possible health effects that received major national attention. The information in this site is drawn primarily from two publications: Monitoring the Community for Exposure and Disease, a report to the Agency for Toxic Substances and Disease Registry (Nicholas Ashford, Principal Investigator, and Linda Schierow, Project Manager, Centre for Technology, Policy and Industrial Development, 1991) and Love Canal: Science, Politics, and People (Adeline Gordon Levine, Toronto: D.C. Heath, 1982). Other information is drawn from materials listed in the other Love Canal Resources sections.
The Love Canal neighbourhood is located in the city of Niagara Falls, in western New York State. It officially covers 36 square blocks in the south-eastern corner of the city. Two bodies of water define the northern and southern boundaries of the neighbourhood Bergholtz Creek to the north and the Niagara River one-quarter mile to the south. Open fields are to the east, and the western border is 92nd Street. The canal itself is enclosed by 97th, 99th, Colvin and Frontier Streets.
Love Canal incident is remembered as a "national symbol of a failure to exercise a sense of concern for future generations", as retold by, New York State Health Department Commissioner David Axelrod.....it is an example of ground water pollution
The document discusses various topics related to air pollution including:
1) Definitions of air pollution and examples of early observations of air pollution.
2) Examples of major air pollution episodes from 1930 to 1984 that caused deaths.
3) Health effects of air pollution on respiratory, cardiovascular and other systems.
4) Environmental effects such as damage to ecosystems, property and quality of life.
5) Sources of air pollution including natural processes and man-made stationary, transportation, industrial and waste sources.
The Chisso Corporation dumped mercury waste into Minamata Bay from 1932 to 1968, poisoning the local fishing community and causing "Minamata Disease". Over 3,000 victims suffered physical deformities, brain damage, or death from methylmercury poisoning. It took decades for victims to receive compensation, as Chisso denied responsibility. By 1973, a court ruled Chisso was negligent in its dumping and liable for damages, though compensation continues nearly 50 years later.
Pesticides are chemicals designed to kill pests like weeds, insects, and fungi. They can cause acute poisoning, delayed illnesses, and allergic reactions in humans exposed through various means like ingestion, inhalation, eye or skin contact. Symptoms range from skin/eye irritation to excessive sweating or difficulty breathing. Exposure is prevented through proper storage, use of protective equipment, integrated pest management, and community education. First aid involves washing exposed areas, inducing vomiting only if instructed, and getting medical help. While pesticides boost agriculture, improper use without training harms both human and environmental health.
Biomagnification is the increasing concentration of a substance like pesticides in organisms at higher levels of the food chain. It occurs most often in higher trophic levels where exposure is through food rather than water. An example is DDT, an insecticide used from the 1940s to 1960s that entered the environment and biomagnified up the food chain, negatively impacting bald eagle populations. To control biomagnification, harmful substances should not be put in water systems, toxic pesticides should be avoided, organic foods eaten, and time spent in contaminated areas limited.
Thermal pollution is the increase in temperature of air, water, or land caused by human activity. It occurs when industries and power plants use nearby water sources to cool machinery and discharge warmer water back into lakes or streams, increasing their temperature over time. Other causes include urban sprawl which increases the amount of concrete absorbing heat, deforestation which removes shade-providing trees, and pollution particulates that trap heat. The effects of thermal pollution include decreased oxygen levels in water harming aquatic life, and wildlife populations being unable to adapt to rapid temperature changes.
Polycyclic aromatic hydrocarbons (PAHs) are widely distributed and relocated in the environment as a result of the incomplete combustion of organic matter. Many PAHs and their epoxides are highly toxic, mutagenic and/or carcinogenic to microorganisms as well as to higher systems including humans. Although various physicochemical methods have been used to remove these compounds from our environment, they have many limitations.
Bioaccumulation and biomagnification refer to the increasing concentration of pollutants like pesticides, mercury, and other chemicals as they move up the food chain. Bioaccumulation is when an organism absorbs more of a substance than it eliminates, resulting in increasing concentration over time. Biomagnification occurs when concentrations increase at each trophic level, so organisms at the top of food chains face greater exposure. Pollutants like DDT, PCBs, and mercury are especially prone to bioaccumulation and biomagnification due to their persistence and ability to concentrate in fatty tissues. This can negatively impact wildlife and pose risks to human health through consumption of contaminated fish and seafood.
1) The document provides background information on the 1984 Bhopal gas tragedy in India, where a leak of methyl isocyanate gas from a Union Carbide pesticide plant killed thousands.
2) It describes the events leading up to the leak, including safety issues and cost-cutting measures at the plant.
3) Two theories for the cause of the leak are described - accidental water contamination during pipe cleaning, and sabotage by an employee.
4) The aftermath of the disaster is discussed, including health impacts, environmental contamination, legal issues, and policy changes implemented.
5) Lessons from Bhopal include the need for emergency planning, public information, and controlling industrial hazards near populations.
The document discusses water quality standards and issues in India. It notes that while India receives significant rainfall, it is unevenly distributed and water resources are overexploited, resulting in major water quality problems. The major sources of water pollution are domestic sewage (26,254 mld generated but only 6,955 mld treated), industrial wastewater (13,468 mld generated but only 60% treated), and agricultural runoff. This pollution contributes to issues like pathogenic contamination, eutrophication, and depletion of dissolved oxygen. National water quality monitoring tests for over 30 parameters to assess core water quality issues across India. Key water quality parameters that are discussed include pH, turbidity, hardness, TDS, and various
The Love Canal disaster involved a neighborhood in Niagara Falls, New York that was built on top of a former chemical waste dump containing over 21,000 tons of toxic waste. In the late 1970s, residents noticed high rates of cancer and birth defects, which were eventually traced to the chemical waste leaking into the soil and water supply from the dump located under the neighborhood. Over 800 families were evacuated and reimbursed for their homes after extensive legal battles and media coverage brought attention to the environmental and public health crisis.
This document discusses oil pollution, including its sources, effects, and control measures. It notes that oil pollution endangers aquatic life and coastal environments. Major sources include cargo tanker washing, oil spills during transport, bilge dumping, and accidents. Effects range from reduced oxygen in water, harm to marine ecosystems and wildlife, and human health impacts. Control methods encompass physical removal techniques like skimming, as well as chemical dispersion and biological degradation using microorganisms. The overall document aims to raise awareness about oil pollution and the need to protect ocean environments.
This document discusses various types of environmental toxicology and pollution. It notes that chemicals can have global impacts through long-range atmospheric transport and persist in the environment far from where they were used. Examples of specific issues covered include acid rain from air pollution damaging ecosystems, stratospheric ozone depletion from CFCs requiring international agreements like the Montreal Protocol, and global warming from fossil fuel emissions trapping heat via the greenhouse effect. The document stresses that environmental changes can ultimately expose humans through multiple routes, so comprehensive risk assessments are needed.
The document discusses several topics related to hazardous and toxic wastes:
1. Toxic materials used industrially can harm workers' health and hazardous wastes such as heavy metals and pesticides can cause health problems if improperly handled.
2. Minamata disease is a neurologic disorder caused by methyl mercury poisoning from industrial waste discharged into Minamata Bay in Japan. Mercury poisoning through fish consumption affected local communities.
3. The document provides details on ionizing radiation, which can damage cells and DNA, and non-ionizing radiation, which includes optical radiation and electromagnetic fields that can cause thermal or electrical harm in high doses.
The document discusses several topics related to hazardous and toxic wastes:
1) Toxic materials used industrially can harm workers' health. Hazardous wastes include toxic, reactive, radioactive, and infectious medical wastes which threaten human and environmental health if improperly handled.
2) Minamata disease is caused by methyl mercury poisoning from industrial wastewater discharged into Minamata Bay in Japan. Mercury contamination of fish through industrial waste entering waterways can poison humans through fish consumption.
3) The document provides 10 points on Minamata disease, covering what type of disease and substance caused it, patient numbers, the responsible company, impacts to the bay and patients, and lessons on environmental
Aquaculture In China--Complexities Surrounding the Fishing IndustryThe Ocean Foundation
The collapse of wild fish stocks has introduced new opportunities in aquaculture to expand operations from inland to offshore. China in the last 30 years has become an extraordinary leader in fish production and distribution. Since 2001 when it joined the World Trade Organization, productivity has gone up and trade has improved dramatically particularly in aquatic products. But, many problems continue to submerge rather than afloat the aquaculture industry. Disease, illegal drug use, and banned feed methods contribute to global concerns on how fish farming is currently managed in China. While the Chinese government has made tremendous strides to meeting trade standardization objectives, the failure to execute appropriate environmental enforcement at the national level devalues enhancement and conservation efforts of fisheries in numerous provinces. This paper will explore a wide range of related topics encompassing China’s rise in aquaculture with a respect to environmental protection, health and safety.
Eco Friendly Sustainable Development In AniYash Mahendra
This document provides an analysis of policy and development strategies to promote eco-friendly and sustainable development in the Andaman and Nicobar Islands (ANI). It begins with an introduction to the tribes and economic opportunities in ANI, as well as the challenges to development. It then discusses the history of development in ANI under British rule and post-independence. Several forest policies and their evolution in India are examined. Successful development models employed elsewhere in India, such as eco-tourism, cooperative models, and natural solutions by tribal societies, are studied. The document proposes how these models could be applied to ANI to promote sustainable development while protecting the environment and tribal communities.
Surfer Against Sewage is a charity founded in 1990 by surfers in Cornwall, England to improve ocean and beach conditions. They campaign for issues like sewage pollution, marine litter, climate change, and toxic chemicals. Some of their impacts include pressuring a water company to extend its use of UV treatment on sewage and organizing beach cleanups. Going forward, they aim to educate the public and influence policymakers to further safeguard coastlines through volunteering, research, and challenging industries to improve standards.
Water and noise pollution pose threats to human and environmental health. Water pollution occurs when harmful substances are directly or indirectly discharged into bodies of water. It has various sources like industrial and agricultural runoff. This causes issues like algal blooms and eutrophication that deplete oxygen and endanger aquatic life. Noise pollution is unwanted sound that disturbs humans and wildlife. Major sources are transportation, construction, and industrial activities. Both can negatively impact health, concentration, and hearing if not properly controlled through laws, public awareness, and green infrastructure.
Organic and inorganic trace contaminates detection using AASMelroy Castalino
Determining the presence of organic trace contaminates along with inorganic trace contaminants in water bodies using atomic absorption spectroscopy technique
“VALUE CHAIN ANALYSIS OF AQUACULTURE DEVELOPMENT IN MYANMAR” 3. chapter (3)Aung Lwin
The document discusses the history and development of Myanmar's fisheries sector. It notes that fisheries provide an important source of protein and livelihoods. The sector is managed by the Ministry of Agriculture, Livestock and Irrigation and the Department of Fisheries. Freshwater fisheries have historically focused on the country's extensive river systems. The sector has developed in recent decades, with aquaculture production growing dramatically after legal reforms in the 1990s. International organizations and the Myanmar Fisheries Federation also play roles in supporting the fisheries sector.
008 Essay Example Dialogue Narrative With Examples Selo Yogawithjo Co ...Lindsey Rivera
Here are the key differences between a formal and informal place setting:
In a formal place setting:
- Flatware is arranged from the outside in according to when each piece will be used
- Napkins are placed to the left of the forks
- Glasses are placed above the knives and napkins
In an informal place setting:
- Flatware can be placed in any order and arrangement
- Napkins may be placed in the lap or left of the plate
- Glasses are placed above the knives or at the top right of the place setting
The main differences are that a formal place setting has a strict order and arrangement of items, while an informal setting is more flexible. Proper etiqu
This document summarizes information about the Citarum River in Indonesia. It provides background on the river being one of the largest in West Java and a source of life that is now considered one of the most polluted rivers. Urbanization, textile industries and other factories dumping waste are causing increasing heavy metal pollution which is negatively impacting the fish populations and people's health. The Asian Development Bank has approved a $500 million loan for a 15-year clean up plan, but factories continue to pollute the river.
The document discusses several environmental issues including the Fukushima nuclear disaster in Japan, cancer villages in China caused by industrial pollution, and various forms of pollution that are problems in India like air, water, and land pollution. It also discusses Japan's approach to waste management which relies on advances in recycling and consumer participation. Preventing environmental problems involves individual actions like reducing waste and using public transport as well as stopping deforestation and pollution of water sources.
Minamata disease is a nervous system disorder caused by eating fish and shellfish contaminated with methyl mercury, a byproduct discharged from acetaldehyde factories into the water. In Minamata, many people contracted the disease in the 1950s after consuming large amounts of contaminated seafood. Since then, the city has worked to regenerate by improving waste management, recycling, and promoting environmentally-friendly businesses to prevent future pollution issues and protect human health and dignity.
Minamata disease is a nervous system disorder caused by eating fish and shellfish contaminated with methyl mercury, a byproduct discharged from acetaldehyde factories into the water. In Minamata, many people contracted the disease in the 1950s after consuming large amounts of contaminated seafood. Since then, the city has worked to regenerate the area through waste reduction initiatives and emphasizing environmental protection, health, and welfare.
Minamata disease is a nervous system disorder caused by eating fish and shellfish contaminated with methyl mercury, a byproduct discharged from acetaldehyde factories into the water. In Minamata, many people contracted the disease in the 1950s after eating large amounts of contaminated seafood. Since then, the city has worked to regenerate by improving waste management, recycling, and promoting environmentally-friendly businesses to prevent another such incident and protect human life.
The document is a draft report of a fact-finding mission investigating the effects of the Northern Rangelands Trust's (NRT) operations on the Biliqo-Buulessa Community Conservancy in Isiolo County, Kenya. The mission found that:
1) NRT has violated the rights of the community by restricting their access to grazing lands and frustrating their attempts to hold meetings about the conservancy.
2) Since establishing the conservancy, there has been an increase in human-wildlife conflict and cattle rustling between the Borana and Samburu communities, with claims that NRT facilitates the latter.
3) Most community members had no say in forming the conservancy and
The document discusses various environmental issues around the world. It describes cancer villages in China where industrial pollution has caused high cancer rates. It also discusses nuclear power plant disasters in Japan, pollution problems in India like contaminated rivers and floods, and ways to prevent issues like global warming by reducing waste and planting trees. Japan's waste management relies on recycling, incineration, labeling, and consumer participation while India faces challenges from air, water, and land pollution.
The document discusses various types of environmental pollution including air, water, and sound pollution. It provides examples of how each type of pollution occurs and impacts human health. Specific instances like the Bhopal gas leak that caused many deaths are mentioned. The document also outlines various measures that can be taken to control pollution at both the governmental and individual level. This includes preventing pollution during development projects, educating children, modernizing equipment, waste management, and encouraging recycling among others. The key message is that collective effort is needed from various groups to tackle environmental pollution and protect resources for future generations.
The T cell receptor (TCR) is a protein complex found on the surface of T cells that is responsible for recognizing fragments of antigen bound to MHC molecules. It consists of an alpha and beta chain, with 95% of T cells containing these chains and 5% containing gamma and delta chains instead. Each chain contains a variable region that binds the peptide-MHC complex and a constant region near the cell membrane. The variable regions contain three hypervariable complementarity-determining regions important for antigen recognition. The TCR is associated with CD3 proteins that transmit activation signals into the T cell upon peptide binding. TCR diversity arises from genetic recombination of DNA segments during T cell development.
This document discusses T cell activation and maturation. It describes the processes of negative and positive selection that screen T cells. T cell activation occurs through engagement of the T cell receptor and co-stimulatory molecules by MHC peptide and co-stimulatory molecules on antigen presenting cells. Binding of the T cell receptor provides the first signal, while co-stimulation provides the second signal required for an effective immune response.
The document summarizes the major histocompatibility complex (MHC), which screens T cells so that only those capable of binding to MHC molecules are maintained. It discusses MHC restriction, whereby a T cell only recognizes a peptide bound to a particular MHC variant. MHC molecules are highly polymorphic, affecting the range of bound peptides and interactions with T cell receptors. MHC class I presents intracellular peptides to cytotoxic T cells, while MHC class II presents extracellular peptides to T helper cells, leading to different immune responses.
VDJ recombination is the mechanism by which B cells generate antibody diversity. It involves genetic recombination of variable (V), diversity (D), and joining (J) gene segments in B cell progenitors. This creates a unique B cell receptor on each mature B cell. The process occurs in two steps - first recombining the heavy chain loci, then the light chain loci, without a D segment. Key enzymes like RAG and TdT introduce randomness to generate the vast antibody repertoire essential for recognizing diverse pathogens.
Hypersensitivity refers to undesirable immune reactions, including allergies and autoimmunity. There are four main types of hypersensitivity reactions. Type I reactions are immediate and involve IgE antibodies binding to mast cells. Type II reactions are cytotoxic and involve IgG or IgM binding to cells and tissues. Type III reactions involve immune complex deposition in tissues, activating complement and attracting neutrophils. Type IV reactions are delayed, involving sensitized T cells responding 24+ hours after antigen exposure.
Cytokines are low molecular weight proteins that are secreted by cells of the immune system and other cells to regulate immune responses. They act as signaling molecules between cells through specific high-affinity receptors. Cytokines control processes like activation, growth, and differentiation of immune cells. They are classified based on their cellular source (monokines, lymphokines) or functional roles (interleukins, interferons, tumor necrosis factors, colony-stimulating factors, chemokines, growth factors). Binding of cytokines to their receptors triggers intracellular signaling cascades that regulate gene expression. Dysregulation of cytokines can contribute to diseases like cytokine release syndrome. Key cytokines discovered at the National Cancer Institute, like interleukin-2, interleukin-
The complement system consists of serum proteins that exist as inactive precursors and activate in a cascade reaction. It has three activation pathways: classical, alternative, and lectin. The classical pathway is triggered by antibody binding, while the alternative pathway activates spontaneously. The lectin pathway involves MBL binding carbohydrates on microbes. All three pathways result in the membrane attack complex, which inserts into microbial cell walls, causing lysis. Complement also enhances phagocytosis via opsonization.
The B cell receptor is a transmembrane protein on B cells that is composed of a membrane-bound immunoglobulin molecule and a signal transduction moiety. The B cell receptor consists of an Ig molecule anchored to the cell's surface and has two key functions: signal transduction upon antigen interaction and internalization of antigens for processing and presentation to T cells. The B cell co-receptor is a complex of CD19, CD21, and CD81 expressed on mature B cells.
Group 2 students - Wajjiha Amjad, Ayesha Ishtiaq, Sheeza Arif, and Shabana Noor - submitted a report on antibodies to Dr. Sadaf. The report defines antibodies and discusses their structure, including heavy and light chains that form a Y-shape. It also describes how antibodies bind to antigens and the variable and constant regions that determine specificity and effector functions. Furthermore, it explains how somatic hypermutation and VDJ recombination increase antibody diversity to target the wide range of pathogens encountered. The report concludes that monoclonal antibodies are better for therapeutic applications while polyclonal antibodies are generally preferable for research due to advantages in tolerance and epitope recognition.
The document discusses adaptive immunity and the immune response. It describes the four phases of the adaptive immune response as encounter, activation, attack, and memory. Acquired immunity develops over one's lifetime from vaccines, infections, or antibodies from others. The adaptive immune response involves B cells, helper T cells and cytotoxic T cells. It also discusses the specificity, adaptiveness, discrimination between self and non-self, and memory properties of the adaptive immune response. The major cell types involved are T helper cells, cytotoxic T cells, T memory cells, and regulatory T cells. The roles and mechanisms of these cell types are described in detail.
The document discusses innate immunity and the components that make up the innate immune system. It describes the innate immune system as the first line of defense against pathogens and antigens. The innate immune system acts immediately and provides non-specific protection. It consists of physical, chemical, and biological barriers that pathogens encounter. If pathogens breach these barriers, the cellular components of the innate immune system engage, including phagocytic cells, dendritic cells, natural killer cells, and the complement system. The innate immune system provides a rapid but non-specific response to protect the body from infection.
The document provides an overview of the immune system presented by Dr. Sadaf Moeez. It defines key terms like immune system, immunology, immunity, and immune response. It describes the immune system as the cells, tissues, and molecules that mediate resistance to infections. The key tasks of the immune system are recognition of infections, effector functions to eliminate infections, regulation to prevent damage to the body, and memory to generate a strong secondary response. The document also discusses immunity, pathogens, antigens, types of immunity including innate and acquired, and antigens including exogenous and endogenous antigens.
The primary lymphoid organs that create lymphocytes are the bone marrow and thymus. The bone marrow produces B cells and some T cells, while the thymus matures T cells. Secondary lymphoid organs where lymphocytes are activated include lymph nodes, the spleen, tonsils, appendix, and Peyer's patches in the intestine. These organs work to filter the lymph and blood, recognize and eliminate pathogens and foreign cells, and support immune system functions.
This document discusses endocytosis and inflammation. It defines endocytosis as the process by which cells take in material from outside through membrane vesicles. There are four main types of endocytosis: phagocytosis, pinocytosis, receptor-mediated endocytosis, and caveolae. Phagocytosis specifically refers to the engulfing of large solid particles by immune cells, aided by opsonins and surface receptors like toll-like receptors. Inflammation is the immune response to infection or injury, marked by redness, swelling, heat and pain. Key events are the recruitment of phagocytes and the release of cytokines and acute phase proteins from the liver to combat pathogens and initiate healing. Fever occurs as part of inflammation and is induced by
Carbohydrates are organic compounds made of carbon, hydrogen, and oxygen. They include sugars (monosaccharides and disaccharides) and starches/fibers (polysaccharides). Monosaccharides like glucose are the simplest type, while polysaccharides are long chains of monosaccharides joined by glycosidic bonds. Carbohydrates serve important functions like energy storage, structure in cell walls, and as components of other biomolecules. They are classified based on their structure as monosaccharides, disaccharides, oligosaccharides, or polysaccharides.
Zika virus is spread by Aedes mosquitoes and can cause fever, rash and joint pain. It is particularly dangerous for pregnant women as it can cause microcephaly in fetuses. The virus was first identified in Uganda in 1947 and recent outbreaks have occurred in South America. It is usually mild and self-limiting, though acetaminophen can help relieve symptoms. Prevention focuses on reducing mosquito bites through clothing, repellents and nets. Currently there is no vaccine or specific antiviral treatment.
Group A presented on the topic of Corona virus. Their presentation defined corona virus as a highly contagious respiratory disease caused by the SARS-CoV-2 virus. It outlined the initial outbreak in Wuhan, China in late 2019 and the subsequent declaration of a global pandemic by WHO in March 2020. The presentation described the virus's morphology, life cycle within host cells, common symptoms, treatment options including self-care and medical care such as oxygen supplementation.
This document discusses biosafety considerations for gene therapy including criteria for categorizing biological risk, the history of human gene therapy, and risk management when working with adeno-associated virus (AAV) vectors. It provides guidelines for ensuring appropriate containment procedures based on risk group classifications from organizations like the NIH and WHO. Gene therapy aims to treat disease by replacing or correcting defective genes, and AAV vectors are promising for gene transfer and expression due to their ability to infect cells and remain as episomes.
Viral replication involves six key steps: 1) attachment, where the virus attaches to the host cell; 2) penetration, where the virus enters the host cell; 3) uncoating and replication, where the viral genetic material incorporates into the host cell and induces replication; 4) assembly, where new viral components are assembled; 5) release, where new viruses are released by cell lysis or budding; 6) for retroviruses like HIV, reverse transcription must occur to convert viral RNA into DNA before integration and replication. The overall process allows the virus to hijack the host cell's machinery to produce new viral progeny and spread infection.
Viruses are classified into six groups based on their nucleic acid composition and ability to produce mRNA. The groups are: 1) dsDNA viruses, 2) ssDNA viruses, 3) dsRNA viruses, 4) ssRNA viruses with positive strands, 5) ssRNA viruses with negative strands, and 6) ssRNA viruses with reverse transcriptase. Virus replication involves adsorption to host cells, penetration, uncoating, replication of the viral genome, transcription and translation to produce proteins, assembly of new virus particles, and release.
Sectional dentures for microstomia patients.pptxSatvikaPrasad
Microstomia, characterized by an abnormally small oral aperture, presents significant challenges in prosthodontic treatment, including limited access for examination, difficulties in impression making, and challenges with prosthesis insertion and removal. To manage these issues, customized impression techniques using sectional trays and elastomeric materials are employed. Prostheses may be designed in segments or with flexible materials to facilitate handling. Minimally invasive procedures and the use of digital technologies can enhance patient comfort. Education and training for patients on prosthesis care and maintenance are crucial for compliance. Regular follow-up and a multidisciplinary approach, involving collaboration with other specialists, ensure comprehensive care and improved quality of life for microstomia patients.
Test bank advanced health assessment and differential diagnosis essentials fo...rightmanforbloodline
Test bank advanced health assessment and differential diagnosis essentials for clinical practice 1st edition myrick.
Test bank advanced health assessment and differential diagnosis essentials for clinical practice 1st edition myrick.
Test bank advanced health assessment and differential diagnosis essentials for clinical practice 1st edition myrick.
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The story of Dr. Ranjit Jagtap's daughters is more than a tale of inherited responsibility; it's a narrative of passion, innovation, and unwavering commitment to a cause greater than oneself. In Poulami and Aditi Jagtap, we see the beautiful continuum of a father's dream and the limitless potential of compassion-driven healthcare.
Cyclothymia Test: Diagnosing, Symptoms, Treatment, and Impact | The Lifescien...The Lifesciences Magazine
The cyclothymia test is a pivotal tool in the diagnostic process. It helps clinicians assess the presence and severity of symptoms associated with cyclothymia.
Research, Monitoring and Evaluation, in Public Healthaghedogodday
This is a presentation on the overview of the role of monitoring and evaluation in public health. It describes the various components and how a robust M&E system can possitively impact the results or effectiveness of a public health intervention.
Basics of Electrocardiogram
CONTENTS
●Conduction System of the Heart
●What is ECG or EKG?
●ECG Leads
●Normal waves of ECG.
●Dimensions of ECG.
● Abnormalities of ECG
CONDUCTION SYSTEM OF THE HEART
ECG:
●ECG is a graphic record of the electrical activity of the heart.
●Electrical activity precedes the mechanical activity of the heart.
●Electrical activity has two phases:
Depolarization- contraction of muscle
Repolarization- relaxation of muscle
ECG Leads:
●6 Chest leads
●6 Limb leads
1. Bipolar Limb Leads:
Lead 1- Between right arm(-ve) and left arm(+ve)
Lead 2- Between right arm(-ve) and left leg(+ve)
Lead 3- Between left arm(-ve)
and left leg(+ve)
2. Augmented unipolar Limb Leads:
AvR- Right arm
AvL- Left arm
AvF- Left leg
3.Chest Leads:
V1 : Over 4th intercostal
space near right sternal margin
V2: Over 4th intercostal space near left sternal margin
V3:In between V2 and V4
V4:Over left 5th intercostal space on the mid
clavicular line
V5:Over left 5th intercostal space on the anterior
axillary line
V6:Over left 5th intercostal space on the mid
axillary line.
Normal ECG:
Waves of ECG:
P Wave
•P Wave is a positive wave and the first wave in ECG.
•It is also called as atrial complex.
Cause: Atrial depolarisation
Duration: 0.1 sec
QRS Complex:
•QRS’ complex is also called the initial ventricular complex.
•‘Q’ wave is a small negative wave. It is continued as the tall ‘R’ wave, which is a positive wave.
‘R’ wave is followed by a small negative wave, the ‘S’ wave.
Cause:Ventricular depolarization and atrial repolarization
Duration: 0.08- 0.10 sec
T Wave:
•‘T’ wave is the final ventricular complex and is a positive wave.
Cause:Ventricular repolarization Duration: 0.2 sec
Intervals and Segments of ECG:
P-R Interval:
•‘P-R’ interval is the interval
between the onset of ‘P’wave and onset of ‘Q’ wave.
•‘P-R’ interval cause atrial depolarization and conduction of impulses through AV node.
Duration:0.18 (0.12 to 0.2) sec
Q-T Interval:
•‘Q-T’ interval is the interval between the onset of ‘Q’
wave and the end of ‘T’ wave.
•‘Q-T’ interval indicates the ventricular depolarization
and ventricular repolarization,
i.e. it signifies the
electrical activity in ventricles.
Duration:0.4-0.42sec
S-T Segment:
•‘S-T’ segment is the time interval between the end of ‘S’ wave and the onset of ‘T’ wave.
Duration: 0.08 sec
R-R Interval:
•‘R-R’ interval is the time interval between two consecutive ‘R’ waves.
•It signifies the duration of one cardiac cycle.
Duration: 0.8 sec
Dimension of ECG:
How to find heart rhytm of the heart?
Regular rhytm:
Irregular rhytm:
More than or less than 4
How to find heart rate using ECG?
If heart Rhytm is Regular :
Heart rate =
300/No.of large b/w 2 QRS complex
= 300/4
=75 beats/mins
How to find heart rate using ECG?
If heart Rhytm is irregular:
Heart rate = 10×No.of QRS complex in 6 sec 5large box = 1sec
5×6=30
10×7 = 70 Beats/min
Abnormalities of ECG:
Cardiac Arrythmias:
1.Tachycardia
Heart Rate more than 100 beats/min
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The Ultimate Guide in Setting Up Market Research System in Health-TechGokul Rangarajan
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
"Market Research it too text-booky, I am in the market for a decade, I am living research book" this is what the founder I met on the event claimed, few of my colleagues rolled their eyes. Its true that one cannot over look the real life experience, but one cannot out beat structured gold mine of market research.
Many 0 to 1 startup founders often overlook market research, but this critical step can make or break a venture, especially in health tech.
But Why do they skip it?
Limited resources—time, money, and manpower—are common culprits.
"In fact, a survey by CB Insights found that 42% of startups fail due to no market need, which is like building a spaceship to Mars only to realise you forgot the fuel."
Sudharsan Srinivasan
Operational Partner Pitchworks VC Studio
Overconfidence in their product’s success leads founders to assume it will naturally find its market, especially in health tech where patient needs, entire system issues and regulatory requirements are as complex as trying to perform brain surgery with a butter knife. Additionally, the pressure to launch quickly and the belief in their own intuition further contribute to this oversight. Yet, thorough market research in health tech could be the key to transforming a startup's vision into a life-saving reality, instead of a medical mishap waiting to happen.
Example of Market Research working
Innovaccer, founded by Abhinav Shashank in 2014, focuses on improving healthcare delivery through data-driven insights and interoperability solutions. Before launching their platform, Innovaccer conducted extensive market research to understand the challenges faced by healthcare organizations and the potential for innovation in healthcare IT.
Identifying Pain Points: Innovaccer surveyed healthcare providers to understand their difficulties with data integration, care coordination, and patient engagement. They found widespread frustration with siloed systems and inefficient workflows.
Competitive Analysis: Analyzed competitors offering similar solutions in healthcare analytics and interoperability. Identified gaps in comprehensive data aggregation, real-time analytics, and actionable insights.
Regulatory Compliance: Ensured their platform complied with HIPAA and other healthcare data privacy regulations. This compliance was crucial to gaining trust from healthcare providers wary of data security issues.
Customer Validation: Conducted pilot programs with several healthcare organizations to validate the platform's effectiveness in improving care outcomes and operational efficiency. Gathered feedback to refine features and user interface.
2024 Media Preferences of Older Adults: Consumer Survey and Marketing Implica...Media Logic
When it comes to creating marketing strategies that target older adults, it is crucial to have insight into their media habits and preferences. Understanding how older adults consume and use media is key to creating acquisition and retention strategies. We recently conducted our seventh annual survey to gain insight into the media preferences of older adults in 2024. Here are the survey responses and marketing implications that stood out to us.
Health Tech Market Intelligence Prelim Questions -Gokul Rangarajan
The Ultimate Guide to Setting up Market Research in Health Tech part -1
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
This lays foundation of scoping research project what are the
Before embarking on a research project, especially one aimed at scoping and defining parameters like the one described for health tech IT, several crucial considerations should be addressed. Here’s a comprehensive guide covering key aspects to ensure a well-structured and successful research initiative:
1. Define Research Objectives and Scope
Clear Objectives: Define specific goals such as understanding market needs, identifying new opportunities, assessing risks, or refining pricing strategies.
Scope Definition: Clearly outline the boundaries of the research in terms of geographical focus, target demographics (e.g., age, socio-economic status), and industry sectors (e.g., healthcare IT).
3. Review Existing Literature and Resources
Literature Review: Conduct a thorough review of existing research, market reports, and relevant literature to build foundational knowledge.
Gap Analysis: Identify gaps in existing knowledge or areas where further exploration is needed.
4. Select Research Methodology and Tools
Methodological Approach: Choose appropriate research methods such as surveys, interviews, focus groups, or data analytics.
Tools and Resources: Select tools like Google Forms for surveys, analytics platforms (e.g., SimilarWeb, Statista), and expert consultations.
5. Ethical Considerations and Compliance
Ethical Approval: Ensure compliance with ethical guidelines for research involving human subjects.
Data Privacy: Implement measures to protect participant confidentiality and adhere to data protection regulations (e.g., GDPR, HIPAA).
6. Budget and Resource Allocation
Resource Planning: Allocate resources including time, budget, and personnel required for each phase of the research.
Contingency Planning: Anticipate and plan for unforeseen challenges or adjustments to the research plan.
7. Develop Research Instruments
Survey Design: Create well-structured surveys using tools like Google Forms to gather quantitative data.
Interview and Focus Group Guides: Prepare detailed scripts and discussion points for qualitative data collection.
8. Sampling Strategy
Sampling Design: Define the sampling frame, size, and method (e.g., random sampling, stratified sampling) to ensure representation of target demographics.
Participant Recruitment: Plan recruitment strategies to reach and engage the intended participant groups effectively.
9. Data Collection and Analysis Plan
Data Collection: Implement methods for data gathering, ensuring consistency and validity.
Analysis Techniques: Decide on analytical approaches (e.g., statistical
Test bank clinical nursing skills a concept based approach 4e pearson educati...rightmanforbloodline
Test bank clinical nursing skills a concept based approach 4e pearson education
Test bank clinical nursing skills a concept based approach 4e pearson education
Test bank clinical nursing skills a concept based approach 4e pearson education
VEDANTA AIR AMBULANCE SERVICES IN REWA AT A COST-EFFECTIVE PRICE.pdfVedanta A
Air Ambulance Services In Rewa works in close coordination with ground-based emergency services, including local Emergency Medical Services, fire departments, and law enforcement agencies.
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nursing management of patient with Empyema pptblessyjannu21
prepared by Prof. BLESSY THOMAS, SPN
Empyema is a disease of respiratory system It is defines as the accumulation of thick, purulent fluid within the pleural space, often with fibrin development.
Empyema is also called pyothorax or purulent pleuritis.
It’s a condition in which pus gathers in the area between the lungs and the inner surface of the chest wall. This area is known as the pleural space.
Pus is a fluid that’s filled with immune cells, dead cells, and bacteria.
Pus in the pleural space can’t be coughed out. Instead, it needs to be drained by a needle or surgery.
Empyema usually develops after pneumonia, which is an infection of the lung tissue. it is mainly caused due in infectious micro-organisms. It can be treated with medications and other measures.
2. WHAT KIND OF DISEASE IS MINAMATA
DISEASE?
• Minamata disease was caused by eating large quantities of fish and
shellfish polluted by methyl mercury discharged into Minamata Bay.
• Minamata disease is not a contagious or genetically transmitted disease.
• It was officially discovered in Minamata, Kumamoto prefecture in 1956,
and in 1968
• the national government announced that this pollution-related disease was
caused by Chisso Co., Ltd..
• The methyl mercury that enters the body mainly attacks the central
nervous system.
3. The symptoms
The symptoms include
1. Numbness and unsteadiness in the legs and
hands,
2. Tiredness,
3. Ringing in the ears,
4. Narrowing of the field of vision,
5. Loss of hearing,
6. Slurred speech, and awkward movements.
7. Some early severe victims of Minamata disease
went insane, became unconscious, and died
within a month of the onset of the disease.
4. • There are also victims with chronic Minamata
disease symptoms, such as headaches,
frequent tiredness, loss of the senses of smell
and taste, and forgetfulness, which are not
easily visible but make daily life difficult.
• Moreover, there are congenital Minamata
disease patients, who were born handicaps
after being attacked by methyl mercury while
in the wombs of their mothers who
consumed polluted fish.
5. No cure for Minamata disease
• No cure for Minamata disease has yet been
discovered, so treatment consists of attempts
to lessen the symptoms and physical
rehabilitation therapy.
• In addition to the physical damage, there is
also social harm, such as discrimination
in relation to Minamata disease.
6. 2. WHAT KIND OF SUBSTANCE IS
ORGANIC MERCURY?
• Humans have had a long history with mercury,
and it is well known, for instance, that
mercury was used in the gold plating of the
Great Buddha in Nara and in the Edo period in
medicine and facial powder. where mercury
was produced and used.
Mercury is classified into inorganic mercury
and organic mercury.
7. • Metallic mercury, which is recognized as
inorganic mercury, is used in the
production of familiar items such as
1. fluorescent lights,
2. batteries, and
3. thermometers.
8. • Methyl mercury which caused Minamata
disease is a type of organic mercury.
• It is a white powdery substance and its smell
is like sulfur in a hot spring.
• It is easily absorbed by gastric and intestinal
organs, and carried by the blood into the
brain as well as the liver, the kidney, and even
into the fetus.
• Methyl mercury is highly poisonous and
causes great damage
9. 3. HOW MANY
MINAMATA DISEASE VICTIMS ARE
THERE?
• As of April 30, 1997, the number of people in
Kumamoto and Kagoshima prefectures who had
applied for certification as Minamata disease
victims numbered more than 17,000.
• Of these 2,265 ( of which 1,484 have passed away
by January 31, 2003 ) were certified by the
government. Moreover, there are 11,540 persons
set as the object of the Minamata disease synthesis
measure medical enterprise which carried out the
last decision in 1997 also including the person who
had already died.
10. Official recognition and / or for
medical assistance.
• Minamata disease, and others who died after
the discovery without submitting an
application form for official recognition and /
or for medical assistance.
• some people did not apply for compensation
for other various reasons, so it is impossible
to know the exact number of victims.
11. Minamata disease reported in other
parts of world
• The disease did not occur only in the Minamata
area. In 1965 Minamata disease broke out along the
Agano River in Niigata prefecture, caused by
mercury discharged by the Showa Denko
corporation.
• Ill-health or damage to one’s health as a result of
mercury poisoning caused by factories was also
reported in China and Canada.
• In recent years rivers and lakes in the Amazon and
Tanzania polluted by mercury have created serious
health concerns.
12. 4. WHAT KIND OF COMPANY
WAS CHISSO?
• Chisso began as a hydroelectric power company in the
late Meiji period. (1908) It built a carbide factory in
Minamata, using the electricity, and before long began
producing chemical fertilizers, becoming one of
Japan’s major chemical companies.
• As Chisso grew so did Minamata. Its population
increased, and Minamata became one of the leading
industrial cities in Kumamoto prefecture.
• A former factory director once served as mayor, and
Chisso’s influence on the region and the
residents’dependence on Chisso grew.
13. Chisso products- post war japan rapid
economic growth
• In addition to chemical fertilizers, Chisso produced
1. Acetic Acid,
2. Vinyl Chloride And
3. The Plasticizers That Were Necessary In Their Production.
• Chisso became one of the companies that made possible
postwar Japan’s rapid economic growth.
•
Since the Taisho period (1912-1926), pollution of the ocean by
the wastewater from the Chisso factory had occasionally
become a problem.
• However, from 1932 to 1968 the company continued to use
inorganic mercury as a catalyst when producing
acetaldehyde.
• .
14. Methyl mercury as a Industrial by-
product
• It was used to make acetic acid and the
plasticizers, and in the course of production
methyl mercury as a by-product was
discharged into the sea until 1966 virtually
without treatment
15. Chisso Fault
• Even after Chisso knew the factory
wastewater was the cause of Minamata
disease, it did not suspend its
operations. In the judgement in the first
Minamata disease trial, this type of
negligent corporate morality was
severely criticized
16. 5. WHAT IS
THE CURRENT SITUATION OF CHISSO?
• Chisso Co., Ltd. has its headquarter in Tokyo and two other
factories in Chiba and Okayama prefectures in addition to
the Minamata factory. The main products of the Chisso
Minamata factory are liquid crystal, preservatives, anti-
desiccation agents, chemical fertilizers, synthetic resin and
so on. The Minamata factory employs more than 554
people as of October 2002, and it is still an important
company in Minamata.
• Chisso has undertaken the big obligation to pay reparations
as a cause company of Minamata disease. Since a
possibility that management might get worse in 1975 and
afterwards, and payment of compensation etc. might
become impossible to Chisso came
17. Kumamoto-prefecture has offered
financial support to Chisso
• Kumamoto-prefecture has offered financial support to
Chisso through prefectural loan issue from 1978 to
2000. (Total loan amount of about 260 billion yen)
However, since it became difficult for Chisso to pay
the borrowed money, the Japanese government will
pay it instead of Chisso from February, 2000 every
year waiting and in the meantime until Chisso can pay
some borrowed money.
There is responsibility which continues the medical
treatment to a patient and compensation of a life in
Chisso. Moreover, influencing to society is also called
for so that the same fault may never occur as a cause
company of Minamata disease.
18. 6. WHAT HAS HAPPENED
TO MINAMATA BAY?
• The sludge in Minamata Bay, of which
the concentration of mercury was
beyond 25 ppm, was dealt with
partly by land reclamation and partly by
dredging at a cost of approximately
48.5 billion yen over 14
years.
19. Use of dividing nets at the entrance to
Minamata Bay
• The quality of water in Minamata Bay is one of the best
in Kumamoto Prefecture in terms of transparency and
cleanliness, so one does not need to worry about
swimming or playing there. In order to prevent the
spread of polluted fish and reassure the residents of
the prefecture, the prefecture put dividing nets at
the entrance to Minamata Bay in 1974, and
enlisted the cooperation of the fishing cooperative to
catch fish in the bay.
• Chisso had been buying the fish that had been caught
and had been disposing them
20. • The concentration of mercury in fish and
shellfish in Minamata bay has continued to
decrease since Chisso stopped its production
of acetaldehyde.
• It was confirmed that there were no species
of fish that contained more mercury than the
provisional national standards ( 0.4 ppm total
mercury, 0.3 ppm methyl mercury) according
to an investigation conducted by Kumamoto
Government in October, 1994.
21. Governor of Kumamoto declared
Minamata bay is safe in July, 1997,
• Therefore, the Governor of Kumamoto
declared Minamata bay is safe in July, 1997,
and the dividing nets were removed in
October. Now it can be said that the fish and
shellfish in Minamata bay are as safe as those
of outside the bay. Even though the dividing
nets had been removed, investigations into
the concentration of mercury in fish and
shellfish continued to be conducted twice a
year for the next three years.
22. • Comprehensive data on the sea of Minamata
which has experienced such large-scale
environmental destruction and the health of
the local residents are to be passed on to the
rest of the world so the most can be made of
the lessons of Minamata disease. In order to
do so, long-term observation is needed.
23. 7. WHAT COMPENSATION
DO THE PATIENTS RECEIVE?
• Patients and Chisso concluded a
compensation agreement in July 1973, based
on the March 1973 court decision of the
Minamata disease trial and the direct
negotiations that took place afterwards.
• Under this agreement, one time consolation
payments of between 16 million and 18
million yen were paid to certified patients.
24. • In addition, annuities, medical expenses,
nursing costs, funeral expenses, hot spring
treatment expenses, and the cost of
acupuncture treatments are paid.
• Also, Chisso uses the interest from a reserve
fund to pay diaper expenses, home help
costs, condolence gifts, massage treatment
expenses, and transportation costs to and
from hospitals.
25. Comprehensive Minamata Disease
Treatment Project.
• Moreover, for those who have not applied for
certification but meet certain requirements such
as experiencing loss of sensation in all four
extremities and having eaten large amounts of
fish and shellfish, Kumamoto and Kagoshima
prefectures pay the medical expenses not
covered by health insurance, and expenses for
other medical treatment (17,200 to 23,500 yen
per month as of November, 2000) through its
Comprehensive Minamata Disease Treatment
Project.
26. • Based on the Final Settlement proposed by
the National Government, those, whether
they are alive or not, who meet certain
requirements for having been affected by
methyl mercury (except for certified
Minamata disease victims) agreed with Chisso
that they would not ask for further
compensation in 1996, and received
compensation payments of 2.6 million yen.
27. WHAT HAVE
THE PATIENTS BEEN REQUESTING?
• More than 40 years have passed since Minamata
disease broke out. For the Minamata disease patients,
the 40 years has seen the continuation of hardship and
strife. What the patients requested through the trials
and negotiations against the administrations and
Chisso was a heartfelt and sincere apology for having
caused Minamata disease and not having helped the
patients. Also, the patients have been requesting that
the victims’ conditions be acknowledged and quick
relief be provided. What they most strongly appealed
for during this period, one of isolation from the local
society, was that they be treated as human beings and
citizens of Minamata.
28. lessons for future generations
• There is no complete cure for Minamata
disease. Most patients go to hospitals every
day for symptomatic treatment and
rehabilitation. As the patients become older,
the number of people who are hospitalized
or receive home medical assistance increases.
29. To live in the community without any
worries
• In this rapid aging society, the patients’ wish
that they be able to live in the community
without any worries is also a common concern
in Minamata. Needless to say, those who can
move their body do what they can manage.
Although farming and fishing are considered
heavy labor, they can help with rehabilitation.
Some patients work for companies. The
patients have learnt to live with their
symptoms.
30. Some patients hesitate to reveal that
they are a Minamata disease victim
• However, prejudice and misunderstanding related
to Minamata disease still remains As such there
are cases in which some patients hesitate to
reveal that they are a Minamata disease victim
even to their family or relatives.
• Others devote themselves to activities such as
talks about their experiences and the lessons for
future generations, hoping that Minamata
disease will never be repeated
31. 9. WHAT IS MOYAI NAOSHI?
• Moyai literally ‘ ’ means to bind boats together
or to do something together. We name
cooperative community projects ‘Moyai Naoshi’,
which stress tackling the Minamata disease issue,
and facing, understanding, and working together
here in Minamata where the relationships among
people and between people and nature were
once destroyed.
• Around the time of the outbreak of Minamata
disease, the Minamata disease patients had
problems mixing with neighbors, because
people thought the disease was contagious.
32. A threat to the existence of Chisso
• Even after the mercury in the wastewater
discharged from Chisso was determined as the
cause of the disease, the victims were ignored
by those who were dependant on Chisso. The
trial and compensation payments were
considered a threat to the existence of
Chisso.
33. Reconstruction of Minamata through
talks and activities
• In addition, the victims experienced
discrimination and malicious slander in relation
to the compensation payments. Among those
who applied for certification, it was said that
some were faking disease symptoms.
• Since the disease was caused by Chisso, on
which Minamata was financially dependent,
strikes broke out followed by hostility among
the residents.
34. 10. WHAT CAN WE LEARN
FROM MINAMATA DISEASE?
• Minamata disease was caused by eating
contaminated fish and shellfish, which were
polluted by industrial waste discharged by
Chisso. At the same time, hostility among
people broke out. We can not think about our
rich materialistic lives
35. • Relations between people supporting different
standpoints have been severed for a long time.
• However, having overcome these
misunderstandings and realizing that hostility
accomplishes nothing, the administration, the
citizens, and the victims of Minamata disease
are taking actions together for the
reconstruction of Minamata through talks and
activities.
36. The citizens of Minamata have
learned
• The citizens of Minamata have learned that water and
food are essential to life, and therefore invaluable, and
that household and industrial waste should not be
allowed to destroy the environment.
•
Mass production, mass consumption, and mass waste
make our lives more convenient and prosperous. Yet,
our environment and health are suffering, surrounded
by
1. exhaust fumes,
2. agricultural chemicals,
3. food preservatives, and
4. various toxic substances.
37. Coexist with nature
• Minamata disease tells us that human beings
can be the perpetrators as well as the victims.
Minamata disease also tell us: to coexist with
nature, based on the idea that we are living
thanks to nature;
• to think about the relations among people,
rivers, and the sea; to think about food which
is safe; to decrease home and industrial waste
and to grapple with recycling; and to tackle
global problems.