Mittelschmerz is a one-sided, lower abdominal pain occurring during ovulation, typically around 14 days before the next menstrual period. Most cases do not require medical intervention and can be managed with over-the-counter pain relievers or home remedies, while severe or persistent pain may indicate a more serious condition. Women experiencing mittelschmerz should track their menstrual cycles and consult a doctor if the pain is severe or accompanied by other concerning symptoms.