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PREGNANCY-INDUCED
HYPERTENSION
(PIH)
by:
Trixie Mariel E. Araune
Jenn Christian C. Bonono
WHAT IS PIH?
►  a condition in in which vasospasm
occurs during pregnancy in both small &
large arteries
► originally called toxemia
► occurs in 5% - 7% of pregnancies




Signs of PIH:
 edema (interstitial effect)
 hypertension (vascular effect)
 proteinuria (kidney effect)
Cause:    UNKNOWN


Risk factors:
 multiple pregnancy
 primiparas (< 20 y.o or > 40 y.o)
 low socioeconomic backgrounds ( poor nutrition)
 5 or more pregnancies
 hydramnios
 heart dse, diabetes, & essential hypertension
CLASSIFICATION OF PIH
1)   Gestational HPN
2)   Mild pre-eclampsia
3)   Severe pre-eclampsia
4)   Eclampsia
ANATOMY & PHYSIOLOGY




          Internal anatomy of the heart
ANATOMY & PHYSIOLOGY




        Blood flow through the circulatory system
ANATOMY & PHYSIOLOGY




         Diagram of human circulation
PATHOPHYSIOLOGY
                      Vasospasm


 Vascular effects    Kidney effects     Interstitial effects



 Vasoconstriction     ↓ed glomeruli      Diffusion of fluid
                    filtration rate &   from bloodstream
                      ↑ed glomeruli      into interstitial
                        membrane
   Poor organ                                 tissue
                       permeability
    perfusion

                    ↑ed serum BUN,
     ↑ed BP           uric acid, &            Edema
                       creatinine


                    ↓ed urine output
                     & proteinuria
Excretory System Anatomy & Physiology

  “ without me in your body, you are nothing but - a waste…”
the   functions
Urinary system, often called as ‘excretory system’, is a body
   system that separates wastes from the body – usually as
   urine or sweat.
As a system, the kidneys, ureters, urinary bladder & the
   urethra works through:
 Maintaining body’s fluid & electrolyte balance.
 Collects water & filter body fluids.
 Removes excess, unnecessary or dangerous materials in
   the body to help maintain homeostasis.
the   anatomy
the   anatomy [the kidneys]
 Are dark-red, slightly flattened, bean
shaped organs about 10 cm long, 5 cm wide
and 4 cm thick weighing approximately 150
grams. Kidneys weigh about 0.5 percent of
total body weight.
 A mass of tiny tubes & each tube is a knot
of capillaries.
Each kidney is composed of numerous
microscopic coiled tubules called nephron or
renal tubules or uriniferous tubules.
The inner surface has a deep notch called
hilus. The ureters, renal artery, renal vein
and the nerves enter the kidney through the
hilus.
The kidney is divided into 2 regions, an
outer region called renal cortex and the inner
region termed renal medulla.
the   anatomy [the ureters]

                    About 28 cm long
                   Carry the urine from the kidneys
                   to the urinary bladder.
                    Arise from the renal pelvis on the
                   medial aspect of each kidney before
                   descending towards the bladder on
                   the front of the psoas major muscle.
                   This "pelviureteric junction" is a
                   common site for the impaction
                   of kidney stones.
                   In the female, the ureters pass
                   through the mesometrium on the
                   way to the urinary bladder.
the   anatomy [the urinary bladder]
                                            It can store about 0.5 to 1 litre of urine
                                           The lower part or neck of the bladder is
                                           guarded by 2 rings of muscle fibres called
                                           sphincters.
                                           The act of voiding of urine is called
                                           micturition.




                              Tips for a healthy bladder

            Here are some tips you can pass onto clients and patients to help
                             them achieve a healthy bladder
                                    Drink plenty of water
                         Limit caffeine alchohol and fizzy drinks
                                 Do pelvic floor exercises
            Don't go to the toilet 'just in case' however also don't hold on too
                                             long
                             Keep your weight under control
                                         Don't smoke
                          Don't strain when going to the toilet
the    anatomy [the urethra]

 Tube that passes urine from
the urinary bladder to the
outside of the body.
 In females it is about 2 - 3 cm
long and carries only urine.
In male, urethra is about 20
cm long and carries urine as
well as the spermatic fluid.
the            .com
      references



          http://www.tena.com.au/professionals/healthcare-professionals/incontinence-management-centre/about-incont
          http://www.medterms.com/script/main/art.asp?articlekey=5907
          http://education.yahoo.com/reference/gray/subjects/subject/255
          http://www.lake-mills.k12.ia.us/msources/Health-SS7/ExcretorySystem.htm
          http://www.emc.maricopa.edu/faculty/farabee/biobk/biobookexcret.html
          https://www.facebook.com/
Pre-eclampsia
• Serious metabolic disturbance (toxemia) of
  pregnancy that occurs most often following
  the twentieth week of pregnancy.
• Involves a systemic malfunction of the
  tissue lining the blood vessels (vascular
  endothelium) and is characterized by high
  blood pressure (hypertension), swelling
  (edema), and high amounts of protein in the
  urine (proteinuria)
• It is one of a group of disorders that appear to
  be progressive steps in a single process that
  includes gestational hypertension (blood
  pressure of 140/90 or greater)

Gestational Hypertension
   - when women develops an elevated blood
 pressure (140/90mmHG) but has no
 proteinuria or edema.
Mild Pre-eclampsia
  This condition is characterized by:
• Blood Pressure reading of 140 mm hg systolic,
  or an elevation of 30 mm hg or more systolic
  or 15 mm hg diastolic above the patient's
  prepregnancy level.
• Bp readings are taken on two occasions 6
  hours apart, with special attention to the
  diastolic pressure, which reflects peripheral
  vascular spasm.
• Proteinuria of 1+ or 2+ on a reagent test strip
  or 500 mg/24 hours or more.
• Swelling in the upper part of her body rather
  than the usual ankle edema associated with
  pregnancy.
• Weight gain of more than 1 kg (2 pounds) a
  week in the second trimester and 0.5 kg (1
  pound) a week in the third trimester.
Management:
• Bed rest to facilitate sodium excretion
• Some physicians also prescribe a high-
  protein diet to compensate for the
  protein lost in the urine and, perhaps,
  mild restriction of sodium intake.

   Diuretics are not used for control of edema because they can
   only aggravate the condition by increasing glomerular vessel
   permeability and stimulating angiotension activity.
Severe Preeclampsia
Symptoms
 Blood pressure: 160/110 mmhg
 Proteinuria: 3–4+ on a random
  sample and 5 g on a 24-hour
  sample
 Oliguria: (500 mL or less in 24
  hours or altered renal function
  tests; elevated more than 1.2 mg/
  dL)
 Cerebral or visual disturbances
  (headache, blurred vision)
 Thrombocytopenia
 Hepatic dysfunction
 Elevated serum
  creatinine more than
  1.2 mg/dL
 Extensive peripheral
  edema
 Pulmonary edema
 Epigastric pain
SEVERE
PREECLAMPSIA
NURSING INTERVENTIONS

a. Support bed rest
b. Monitor maternal well- being
c. Monitor fetal well- being
d. Support nutritious diet
e. Administer medications to prevent
  eclampsia
NURSING INTERVENTIONS
•Woman may be admitted to health care facility


•If pregnancy is 36 WEEKS or further along or FETAL
LUNG MATURITY can be confirmed by amniocentesis
 labor can be induced to end pregnancy

•If pregnancy is LESS THAN 36 WEEKS or IMMATURE
LUNG FUNCTION can be revealed by amniocentesis 
interventions will be instituted to attempt to alleviate the
sever symptoms and allow fetus to come in term.
Support bed rest
•woman should be admitted to a
PRIVATE ROOM so she can rest
undisturbed as possible
•raise side rails
•darken the room
•stress can trigger an INCREASE
in BP and can evoke seizures
•make sure a woman receives
clear explanations and allow
opportunities to EXPRESS HER
FEELINGS 
Monitor maternal well- being
•Take BP every 4HOURS or w/
continuous monitoring device

•Obtain blood studies as
ordered(complete blood count,
platelet count, liver function,
blood urea nitrogen, and creatine
and fibrin degradation products

•Type and cross-matching
Monitor maternal well- being
•Obtain daily hematocrit
levels as ordered

•Assess optic fundus

•Obtain daily weights at the
same time each day
                               NORMAL:more than
                               600mL per 24 hours(>
•Indwelling catheter may be    30mL/hr), output lower
                               than this suggests
inserted                       OLIGURIA
Monitor maternal well- being
•Urinary protein & specific
gravity  recorded & measured
with voiding or if with indwelling
catheter, HOURLY

•24-hour urine sample may be
collected for protein and
creatinine clearance
determinations  to evaluate
kidney function
SEVERE PREECLAMPSIA      MILD PREECLAMPSIA



 5g per 24 hours(3+ or 4+ on bet 0.5 and 1g of protein
individual specimen)         every 24 hours(1+ on
                             sample)
. Monitor fetal well-being
•single Doppler auscultation at approximately 4-hour
intervals(FHR may be assessed by an external fetal
monitor)
•Nonstress test or biophysical profile  to assess
uteroplacental sufficiency
•O2 administration  to maintain adequate fetal
oxygenation and prevent fetal bradycardia
MEDICATIONS
DRUG            INDICATION   DOSAGE            COMMENT


Magnesium       Muscle       Loading dose      Infuse loading dose slowly over
sulfate         relaxant;    4–6 g             15–30 min.
Pregnancy       prevents     Maintenance       Always administer as a
risk category   seizures     dose 1–2 g/h IV   piggyback infusion
B                                              Assess respiratory rate, urine
                                               output, deep tendon reflexes,
                                               and clonus every hour.
                                               Keep in mind that urine output
                                               should be over 30 mL/hour and
                                               respiratory rate over 12/min.
                                               Serum magnesium level should
                                               remain below 7.5 mEq/L.
                                               Observe for CNS depression and
                                               hypotonia in infant at birth
MEDICATIONS
DRUG             INDICATION        DOSAGE             COMMENT
Hydralazine      Antihypertensiv   5–10 mg/IV         Administer slowly to avoid sudden
(Apresoline)     e                                    fall in blood pressure.
Pregnancy risk                                        Maintain diastolic pressure over
category C                                            90 mm Hg to ensure adequate
                                                      placental filling.
                                                      Administer slowly. Dose may be
                                                      repeated q 5–10 min (up to 30 mg/
                                                      hour).
                                                      Observe for respiratory depression
                                                      or hypotension in mother and
                                                      respiratory depression and
                                                      hypotonia in infant at birth.

Calcium          Antidote for      1 g/IV (10 mL of   Have prepared at bedside when
gluconate        magnesium         a 10% solution)    administering magnesium sulfate.
Pregnancy risk   intoxication                         Administer at 5 mL/min.
category C
Eliciting A Patellar Reflex
and Ankle Clonus
PATELLAR REFLEX   RESULTS:

                  0 = No response; hypoactive;
                  abnormal
                  1+ = Somewhat diminished
                  response but not abnormal
                  2+ = Average response
                  3+ = Brisker than average but
                  not abnormal
                  4+ = Hyperactive; very brisk;
                  abnormal
ANKLE CLONUS

        RESULTS:

        Mild (2 movements)

        Moderate (3–5
        movements)

        Severe (over 6
        movements)
PROGNOSIS
Sign and symptoms of preeclampsia usually go away within 6
weeks after delivery. However, the high blood pressure
sometimes get worse the first few days after delivery.


If you have had preeclampsia, you are more likely to develop it
again in another pregnancy. However, it is not usually as severe
as the first time.


If you have have high blood pressure during more than one
pregnancy, you are more likely to have high blood pressure
when you get older.


 The infant's risk of death depends on the severity of the
condition and how early the baby is born.
Support a Nutritious Diet
A woman needs a diet:
•moderate to high in protein
•moderate in sodium to
compensate for the protein she
is losing in her urine,


  An intravenous fluid line should be initiated and
  maintained to serve as an emergency route for drug
  administration as well as to administer fluid to reduce
  hemoconcentration and hypovolemia.
Administer Medications to Prevent
               Eclampsia
A hypotensive drug such as hydralazine
(Apresoline) or labetalol (Normodyne) may be
prescribed to reduce hypertension.

- Assess pulse and blood pressure after
administration. Diastolic pressure should not be
lowered below 80 to 90 mm Hg or inadequate
placental perfusion could occur.
Magnesium Sulfate – drug of choice to prevent
eclampsia
      - classified as a cathartic
      - reduces edema by causing a shift in fluid
from the extracellular spaces into the intestine
      - also has a central nervous system
depressant action which lessens the possibility
of seizures
• For magnesium sulfate to
  act as an anticonvulsant,
  blood serum levels must be
  maintained at 5 to 8 mg/100
  mL. If the blood serum level
  rises above this, respiratory
  depression, cardiac
  arrhythmias, and cardiac
  arrest can occur.
The most evident symptoms of overdose
from magnesium sulfate administration
include:

•   decreased urine output
•   depressed respirations
•   reduced consciousness
•   decreased deep tendon
    reflexes
• Because magnesium is excreted from the body
  almost entirely through the urine, urine
  output must be monitored closely to ensure
  adequate elimination.

• If severe oliguria should occur (less than 100
  mL in 4 hours), excessively high serum levels
  of magnesium can result.
Before you administer further magnesium
sulfate, assess the following:
• ensure that urine output is above 25 to 30 mL/hour, with
  a specific gravity of 1.010 or lower
• respirations should be above 12 per minute
• a woman should be able to answer questions asked of
  her
• ankle clonus (a continued motion of the foot) should be
  minimal
• deep tendon reflexes should be present

    Make these assessments every hour if a continuous
    intravenous infusion is being used.
• a solution of 10 mL of a 10%
  calcium gluconate solution (1
  g) should be kept ready
  nearby for immediate
  intravenous administration
  should a woman develop
  signs and symptoms of
  magnesium toxicity, as
  calcium is the specific
  antidote for magnesium
  toxicity
Severe oliguria may be treated by the
intravenous infusion of salt-poor albumin.

   High colloid solution (salt-poor albumin)

call fluid into the bloodstream from interstitial
            tissue by osmotic pressure

 the kidneys will then excrete the extra fluid
    along with magnesium sulfate levels
TABLE 15.7 Drugs Used in Pregnancy-Induced
                  Hypertension


Drug                Indication          Dosage


Magnesium sulfate   Muscle relaxant;    Loading dose 4–6 g
                                        Maintenance dose 1–2
Pregnancy risk      prevents seizures
                                        g/h IV
category B
   Is a grand mal seizure     Symptoms:
    which passes the          -Seizure or coma
    stages of:                  accompanied by signs
   A) Tonic-Clonic             and symptoms of pre-
   B) Coma                     eclampsia
   Usually happens in late
    pregnancy
   But can happen up to
    48 hrs after birth
   Causes of poor fetal      If premature
    prognosis:                 separation of the
   Hypoxia                    placenta from
   Consequent fetal           vasospasm occurs, the
    acidosis                   fetal prognosis is
                               graver.
                              If a fetus must be born
                               before term, all the
                               risks of immaturity will
                               be faced.
   A woman’s blood pressure          Reflexes become
    rises suddenly from                hyperactive
    additional vasospasm              May experience a
   Temperature rises sharply          premonition that
    to 103 to 104 degrees              “something is happening”
    Fahrenheit                        Vascular congestion of the
   Blurring of vision or severe       liver and pancreas can lead
    headache                           to severe epigastric pain
                                       and nausea
                                      Urinary output may
                                       decrease abruptly to less
                                       than 30 mL/hr.
  Risk factors:                gestational diabetes
- greater in nulliparous        prepregnancy obesity
   compared to parous           weight gain during
   women                         pregnancy
- Being a young mother
   (<20 years) or an older
   mother (≥35 years)
   were each associated
   with elevated
   eclampsia risk
Nursing Interventions for a woman
          with Eclampsia
Tonic-Clonic Seizure
TONIC PHASE
- Last approximately 20 secs.
• all the muscles of the woman’s body contract
• Back arches
• Arms and legs stiffen
• Jaw closes abruptly
• Respirations halt because her thoracic muscles
   are held in contraction
Nursing Interventions:
• Priority Care: Maintain a patent airway
• Do not put tongue blade
• Administer oxygen by face mask
• Assess oxygen saturation via a pulse oximeter
• Apply an external fetal heart monitor
Clonic Phase
-last up to 1 minute
• Bladder and bowel muscles contract and relax
• Incontinence of urine and feces may occur.
• Remains cyanotic and may need continued
   oxygen therapy for the fetus

NURSING INTERVENTION
Magnesium Sulfate or Diazepam (Valium) may
 be administered intravenously
Postictal State
• A woman is semicomatose and cannot be
  roused except by painful stimuli for 1 to 4
  hours
• Part of the seizure that may cause premature
  separation of the placenta
• Labor may begin during this period and a
  woman will be unable to report the sensation
  of contraction
Nursing Interventions:
• Keep a woman on her side so secretions can
  drain
• Nothing per Orem
• Continuously assess fetal heart sounds and
  uterine contractions.
• Check for vaginal bleeding every 15 minutes
Birth
There is evidences that the fetus does not
  continue to grow after eclampsia happens, so
  terminating the pregnancy at this point is
  appropriate for both mother and child.
A woman with eclampsia is not a good candidate
  for surgery: she may become hypotensive with
  regional anesthesia.
HELLP
SYNDROME
a variation of PIH named for
the common symptoms that
occur:
     -hemolysis
     -elevated liver enzymes
     -low platelets.
HELLP SYNDROME
 Occurs   in approximately 1 in every 150
  births.
 Results in maternal mortality rate as high
  as 24% and an infant mortality rate as
  high as 35%.
It occurs in:
      -primigravidas
      -multigrvidas
      -some women with pre-eclampsia
SYMPTOMS
 nausea

 Epigastric  pain
 General malaise

 Right Upper Quadrant tenderness from
  liver inflammation.
SYMPTOMS
 Laboratorystudies reveals:
     1. Hemolysis of RBCs-appears
 fragmented on peripheral blood smear

     2.Thrombocytopenia- platelet count
 below 100,000/mm3

     3. Elevated liver enzyme levels
 (alanine aminotransferase-ALT and
 serum aspartate aminotransferase-AST)
THERAPY

 Improve  the platelet count by transfusion
 of fresh-frozen plasma or platelets.
COMPLICATIONS

 Subcapsular  liver hematoma
 Hyponatremia

 Renal failure

 Hypoglycemia
 The   infant is delivered as soon as feasible
  by either vaginal or cesarean birth.
 Maternal hemorrhage may occur at birth
  because of poor clotting activity.
 Epidural anesthesia may not be possible
  because of the low platelet count and the
  high possibility of bleeding at the epidural
  site.
 Laboratory results return to normal after
  birth.
Nursing Diagnoses:

Pregnancy –Induced
Decreased cardiac output related to
              hypovolemia

It can also be related to decreased venous return.

Possibly evidenced by:
d. Edema
e. Shortness of breath
f. Change in mental status
g. Decreased urine output
Deficient Fluid Volume related to loss
        to subcutaneous tissue

It can also be related to a plasma protein loss.

Possibly evidenced by:
d. Edema formation
e. Sudden weight gain
f. Hemoconcentration
g. Nausea & vomiting
h. Epigastric pain
i. Headache
j. Visual changes
k. Decreased urine output
Ineffective Tissue Perfusion related
 to vasoconstriction of blood vessels

It could be related to vasospasm of spiral arteries & relative
    hypovolemia.

Possibly evidenced by:

e. Changes in Fetal heart rate
f. Reduced weight gain
g. Premature delivery
Nursing Interventions
Woman with MILD PIH:
 Monitor Antiplatelet Therapy
 Promote Bed Rest
 Promote Good Nutrition
 Provide Emotional Support
Woman with SEVERE PIH:
 Support bed rest
 Monitor maternal well-being
 Monitor fetal well-being
 Support a nutritious diet
 Administer medications to prevent Eclampsia
Woman with ECLAMPSIA:
II. Patient that has tonic-clonic seizure:
 Maintain a patent airway
 Administer Oxygen face mask
 Turn the woman in her side to prevent aspirations
 Administer Magnesium Sulfate or diazepam via IV
 Assess oxygenation via pulse oximeter
Mcn final!!!

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Mcn final!!!

  • 2. WHAT IS PIH? ► a condition in in which vasospasm occurs during pregnancy in both small & large arteries ► originally called toxemia ► occurs in 5% - 7% of pregnancies Signs of PIH:  edema (interstitial effect)  hypertension (vascular effect)  proteinuria (kidney effect)
  • 3. Cause: UNKNOWN Risk factors:  multiple pregnancy  primiparas (< 20 y.o or > 40 y.o)  low socioeconomic backgrounds ( poor nutrition)  5 or more pregnancies  hydramnios  heart dse, diabetes, & essential hypertension
  • 4. CLASSIFICATION OF PIH 1) Gestational HPN 2) Mild pre-eclampsia 3) Severe pre-eclampsia 4) Eclampsia
  • 5. ANATOMY & PHYSIOLOGY Internal anatomy of the heart
  • 6. ANATOMY & PHYSIOLOGY Blood flow through the circulatory system
  • 7. ANATOMY & PHYSIOLOGY Diagram of human circulation
  • 8. PATHOPHYSIOLOGY Vasospasm Vascular effects Kidney effects Interstitial effects Vasoconstriction ↓ed glomeruli Diffusion of fluid filtration rate & from bloodstream ↑ed glomeruli into interstitial membrane Poor organ tissue permeability perfusion ↑ed serum BUN, ↑ed BP uric acid, & Edema creatinine ↓ed urine output & proteinuria
  • 9.
  • 10. Excretory System Anatomy & Physiology “ without me in your body, you are nothing but - a waste…”
  • 11. the functions Urinary system, often called as ‘excretory system’, is a body system that separates wastes from the body – usually as urine or sweat. As a system, the kidneys, ureters, urinary bladder & the urethra works through:  Maintaining body’s fluid & electrolyte balance.  Collects water & filter body fluids.  Removes excess, unnecessary or dangerous materials in the body to help maintain homeostasis.
  • 12. the anatomy
  • 13. the anatomy [the kidneys]  Are dark-red, slightly flattened, bean shaped organs about 10 cm long, 5 cm wide and 4 cm thick weighing approximately 150 grams. Kidneys weigh about 0.5 percent of total body weight.  A mass of tiny tubes & each tube is a knot of capillaries. Each kidney is composed of numerous microscopic coiled tubules called nephron or renal tubules or uriniferous tubules. The inner surface has a deep notch called hilus. The ureters, renal artery, renal vein and the nerves enter the kidney through the hilus. The kidney is divided into 2 regions, an outer region called renal cortex and the inner region termed renal medulla.
  • 14. the anatomy [the ureters]  About 28 cm long Carry the urine from the kidneys to the urinary bladder.  Arise from the renal pelvis on the medial aspect of each kidney before descending towards the bladder on the front of the psoas major muscle. This "pelviureteric junction" is a common site for the impaction of kidney stones. In the female, the ureters pass through the mesometrium on the way to the urinary bladder.
  • 15. the anatomy [the urinary bladder]  It can store about 0.5 to 1 litre of urine The lower part or neck of the bladder is guarded by 2 rings of muscle fibres called sphincters. The act of voiding of urine is called micturition. Tips for a healthy bladder Here are some tips you can pass onto clients and patients to help them achieve a healthy bladder Drink plenty of water Limit caffeine alchohol and fizzy drinks Do pelvic floor exercises Don't go to the toilet 'just in case' however also don't hold on too long Keep your weight under control Don't smoke Don't strain when going to the toilet
  • 16. the anatomy [the urethra]  Tube that passes urine from the urinary bladder to the outside of the body.  In females it is about 2 - 3 cm long and carries only urine. In male, urethra is about 20 cm long and carries urine as well as the spermatic fluid.
  • 17. the .com references  http://www.tena.com.au/professionals/healthcare-professionals/incontinence-management-centre/about-incont  http://www.medterms.com/script/main/art.asp?articlekey=5907  http://education.yahoo.com/reference/gray/subjects/subject/255  http://www.lake-mills.k12.ia.us/msources/Health-SS7/ExcretorySystem.htm  http://www.emc.maricopa.edu/faculty/farabee/biobk/biobookexcret.html  https://www.facebook.com/
  • 18.
  • 19. Pre-eclampsia • Serious metabolic disturbance (toxemia) of pregnancy that occurs most often following the twentieth week of pregnancy. • Involves a systemic malfunction of the tissue lining the blood vessels (vascular endothelium) and is characterized by high blood pressure (hypertension), swelling (edema), and high amounts of protein in the urine (proteinuria)
  • 20. • It is one of a group of disorders that appear to be progressive steps in a single process that includes gestational hypertension (blood pressure of 140/90 or greater) Gestational Hypertension - when women develops an elevated blood pressure (140/90mmHG) but has no proteinuria or edema.
  • 21. Mild Pre-eclampsia This condition is characterized by: • Blood Pressure reading of 140 mm hg systolic, or an elevation of 30 mm hg or more systolic or 15 mm hg diastolic above the patient's prepregnancy level. • Bp readings are taken on two occasions 6 hours apart, with special attention to the diastolic pressure, which reflects peripheral vascular spasm.
  • 22. • Proteinuria of 1+ or 2+ on a reagent test strip or 500 mg/24 hours or more. • Swelling in the upper part of her body rather than the usual ankle edema associated with pregnancy. • Weight gain of more than 1 kg (2 pounds) a week in the second trimester and 0.5 kg (1 pound) a week in the third trimester.
  • 23. Management: • Bed rest to facilitate sodium excretion • Some physicians also prescribe a high- protein diet to compensate for the protein lost in the urine and, perhaps, mild restriction of sodium intake. Diuretics are not used for control of edema because they can only aggravate the condition by increasing glomerular vessel permeability and stimulating angiotension activity.
  • 25. Symptoms  Blood pressure: 160/110 mmhg  Proteinuria: 3–4+ on a random sample and 5 g on a 24-hour sample  Oliguria: (500 mL or less in 24 hours or altered renal function tests; elevated more than 1.2 mg/ dL)  Cerebral or visual disturbances (headache, blurred vision)  Thrombocytopenia
  • 26.  Hepatic dysfunction  Elevated serum creatinine more than 1.2 mg/dL  Extensive peripheral edema  Pulmonary edema  Epigastric pain
  • 28.
  • 29. NURSING INTERVENTIONS a. Support bed rest b. Monitor maternal well- being c. Monitor fetal well- being d. Support nutritious diet e. Administer medications to prevent eclampsia
  • 30. NURSING INTERVENTIONS •Woman may be admitted to health care facility •If pregnancy is 36 WEEKS or further along or FETAL LUNG MATURITY can be confirmed by amniocentesis  labor can be induced to end pregnancy •If pregnancy is LESS THAN 36 WEEKS or IMMATURE LUNG FUNCTION can be revealed by amniocentesis  interventions will be instituted to attempt to alleviate the sever symptoms and allow fetus to come in term.
  • 31. Support bed rest •woman should be admitted to a PRIVATE ROOM so she can rest undisturbed as possible •raise side rails •darken the room •stress can trigger an INCREASE in BP and can evoke seizures •make sure a woman receives clear explanations and allow opportunities to EXPRESS HER FEELINGS 
  • 32. Monitor maternal well- being •Take BP every 4HOURS or w/ continuous monitoring device •Obtain blood studies as ordered(complete blood count, platelet count, liver function, blood urea nitrogen, and creatine and fibrin degradation products •Type and cross-matching
  • 33. Monitor maternal well- being •Obtain daily hematocrit levels as ordered •Assess optic fundus •Obtain daily weights at the same time each day NORMAL:more than 600mL per 24 hours(> •Indwelling catheter may be 30mL/hr), output lower than this suggests inserted OLIGURIA
  • 34. Monitor maternal well- being •Urinary protein & specific gravity  recorded & measured with voiding or if with indwelling catheter, HOURLY •24-hour urine sample may be collected for protein and creatinine clearance determinations  to evaluate kidney function
  • 35. SEVERE PREECLAMPSIA MILD PREECLAMPSIA 5g per 24 hours(3+ or 4+ on bet 0.5 and 1g of protein individual specimen) every 24 hours(1+ on sample)
  • 36. . Monitor fetal well-being •single Doppler auscultation at approximately 4-hour intervals(FHR may be assessed by an external fetal monitor) •Nonstress test or biophysical profile  to assess uteroplacental sufficiency •O2 administration  to maintain adequate fetal oxygenation and prevent fetal bradycardia
  • 37. MEDICATIONS DRUG INDICATION DOSAGE COMMENT Magnesium Muscle Loading dose Infuse loading dose slowly over sulfate relaxant; 4–6 g 15–30 min. Pregnancy prevents Maintenance Always administer as a risk category seizures dose 1–2 g/h IV piggyback infusion B Assess respiratory rate, urine output, deep tendon reflexes, and clonus every hour. Keep in mind that urine output should be over 30 mL/hour and respiratory rate over 12/min. Serum magnesium level should remain below 7.5 mEq/L. Observe for CNS depression and hypotonia in infant at birth
  • 38. MEDICATIONS DRUG INDICATION DOSAGE COMMENT Hydralazine Antihypertensiv 5–10 mg/IV Administer slowly to avoid sudden (Apresoline) e fall in blood pressure. Pregnancy risk Maintain diastolic pressure over category C 90 mm Hg to ensure adequate placental filling. Administer slowly. Dose may be repeated q 5–10 min (up to 30 mg/ hour). Observe for respiratory depression or hypotension in mother and respiratory depression and hypotonia in infant at birth. Calcium Antidote for 1 g/IV (10 mL of Have prepared at bedside when gluconate magnesium a 10% solution) administering magnesium sulfate. Pregnancy risk intoxication Administer at 5 mL/min. category C
  • 39. Eliciting A Patellar Reflex and Ankle Clonus PATELLAR REFLEX RESULTS: 0 = No response; hypoactive; abnormal 1+ = Somewhat diminished response but not abnormal 2+ = Average response 3+ = Brisker than average but not abnormal 4+ = Hyperactive; very brisk; abnormal
  • 40. ANKLE CLONUS RESULTS: Mild (2 movements) Moderate (3–5 movements) Severe (over 6 movements)
  • 41. PROGNOSIS Sign and symptoms of preeclampsia usually go away within 6 weeks after delivery. However, the high blood pressure sometimes get worse the first few days after delivery. If you have had preeclampsia, you are more likely to develop it again in another pregnancy. However, it is not usually as severe as the first time. If you have have high blood pressure during more than one pregnancy, you are more likely to have high blood pressure when you get older. The infant's risk of death depends on the severity of the condition and how early the baby is born.
  • 42. Support a Nutritious Diet A woman needs a diet: •moderate to high in protein •moderate in sodium to compensate for the protein she is losing in her urine, An intravenous fluid line should be initiated and maintained to serve as an emergency route for drug administration as well as to administer fluid to reduce hemoconcentration and hypovolemia.
  • 43. Administer Medications to Prevent Eclampsia A hypotensive drug such as hydralazine (Apresoline) or labetalol (Normodyne) may be prescribed to reduce hypertension. - Assess pulse and blood pressure after administration. Diastolic pressure should not be lowered below 80 to 90 mm Hg or inadequate placental perfusion could occur.
  • 44. Magnesium Sulfate – drug of choice to prevent eclampsia - classified as a cathartic - reduces edema by causing a shift in fluid from the extracellular spaces into the intestine - also has a central nervous system depressant action which lessens the possibility of seizures
  • 45. • For magnesium sulfate to act as an anticonvulsant, blood serum levels must be maintained at 5 to 8 mg/100 mL. If the blood serum level rises above this, respiratory depression, cardiac arrhythmias, and cardiac arrest can occur.
  • 46. The most evident symptoms of overdose from magnesium sulfate administration include: • decreased urine output • depressed respirations • reduced consciousness • decreased deep tendon reflexes
  • 47. • Because magnesium is excreted from the body almost entirely through the urine, urine output must be monitored closely to ensure adequate elimination. • If severe oliguria should occur (less than 100 mL in 4 hours), excessively high serum levels of magnesium can result.
  • 48. Before you administer further magnesium sulfate, assess the following: • ensure that urine output is above 25 to 30 mL/hour, with a specific gravity of 1.010 or lower • respirations should be above 12 per minute • a woman should be able to answer questions asked of her • ankle clonus (a continued motion of the foot) should be minimal • deep tendon reflexes should be present Make these assessments every hour if a continuous intravenous infusion is being used.
  • 49. • a solution of 10 mL of a 10% calcium gluconate solution (1 g) should be kept ready nearby for immediate intravenous administration should a woman develop signs and symptoms of magnesium toxicity, as calcium is the specific antidote for magnesium toxicity
  • 50. Severe oliguria may be treated by the intravenous infusion of salt-poor albumin. High colloid solution (salt-poor albumin) call fluid into the bloodstream from interstitial tissue by osmotic pressure the kidneys will then excrete the extra fluid along with magnesium sulfate levels
  • 51. TABLE 15.7 Drugs Used in Pregnancy-Induced Hypertension Drug Indication Dosage Magnesium sulfate Muscle relaxant; Loading dose 4–6 g Maintenance dose 1–2 Pregnancy risk prevents seizures g/h IV category B
  • 52.
  • 53. Is a grand mal seizure  Symptoms: which passes the -Seizure or coma stages of: accompanied by signs  A) Tonic-Clonic and symptoms of pre-  B) Coma eclampsia  Usually happens in late pregnancy  But can happen up to 48 hrs after birth
  • 54. Causes of poor fetal  If premature prognosis: separation of the  Hypoxia placenta from  Consequent fetal vasospasm occurs, the acidosis fetal prognosis is graver.  If a fetus must be born before term, all the risks of immaturity will be faced.
  • 55. A woman’s blood pressure  Reflexes become rises suddenly from hyperactive additional vasospasm  May experience a  Temperature rises sharply premonition that to 103 to 104 degrees “something is happening” Fahrenheit  Vascular congestion of the  Blurring of vision or severe liver and pancreas can lead headache to severe epigastric pain and nausea  Urinary output may decrease abruptly to less than 30 mL/hr.
  • 56.  Risk factors:  gestational diabetes - greater in nulliparous  prepregnancy obesity compared to parous  weight gain during women pregnancy - Being a young mother (<20 years) or an older mother (≥35 years) were each associated with elevated eclampsia risk
  • 57. Nursing Interventions for a woman with Eclampsia
  • 58. Tonic-Clonic Seizure TONIC PHASE - Last approximately 20 secs. • all the muscles of the woman’s body contract • Back arches • Arms and legs stiffen • Jaw closes abruptly • Respirations halt because her thoracic muscles are held in contraction
  • 59. Nursing Interventions: • Priority Care: Maintain a patent airway • Do not put tongue blade • Administer oxygen by face mask • Assess oxygen saturation via a pulse oximeter • Apply an external fetal heart monitor
  • 60. Clonic Phase -last up to 1 minute • Bladder and bowel muscles contract and relax • Incontinence of urine and feces may occur. • Remains cyanotic and may need continued oxygen therapy for the fetus NURSING INTERVENTION Magnesium Sulfate or Diazepam (Valium) may be administered intravenously
  • 61. Postictal State • A woman is semicomatose and cannot be roused except by painful stimuli for 1 to 4 hours • Part of the seizure that may cause premature separation of the placenta • Labor may begin during this period and a woman will be unable to report the sensation of contraction
  • 62. Nursing Interventions: • Keep a woman on her side so secretions can drain • Nothing per Orem • Continuously assess fetal heart sounds and uterine contractions. • Check for vaginal bleeding every 15 minutes
  • 63. Birth There is evidences that the fetus does not continue to grow after eclampsia happens, so terminating the pregnancy at this point is appropriate for both mother and child. A woman with eclampsia is not a good candidate for surgery: she may become hypotensive with regional anesthesia.
  • 64. HELLP SYNDROME a variation of PIH named for the common symptoms that occur: -hemolysis -elevated liver enzymes -low platelets.
  • 65. HELLP SYNDROME  Occurs in approximately 1 in every 150 births.  Results in maternal mortality rate as high as 24% and an infant mortality rate as high as 35%. It occurs in: -primigravidas -multigrvidas -some women with pre-eclampsia
  • 66. SYMPTOMS  nausea  Epigastric pain  General malaise  Right Upper Quadrant tenderness from liver inflammation.
  • 67. SYMPTOMS  Laboratorystudies reveals: 1. Hemolysis of RBCs-appears fragmented on peripheral blood smear 2.Thrombocytopenia- platelet count below 100,000/mm3 3. Elevated liver enzyme levels (alanine aminotransferase-ALT and serum aspartate aminotransferase-AST)
  • 68. THERAPY  Improve the platelet count by transfusion of fresh-frozen plasma or platelets.
  • 69. COMPLICATIONS  Subcapsular liver hematoma  Hyponatremia  Renal failure  Hypoglycemia
  • 70.  The infant is delivered as soon as feasible by either vaginal or cesarean birth.  Maternal hemorrhage may occur at birth because of poor clotting activity.  Epidural anesthesia may not be possible because of the low platelet count and the high possibility of bleeding at the epidural site.  Laboratory results return to normal after birth.
  • 72. Decreased cardiac output related to hypovolemia It can also be related to decreased venous return. Possibly evidenced by: d. Edema e. Shortness of breath f. Change in mental status g. Decreased urine output
  • 73. Deficient Fluid Volume related to loss to subcutaneous tissue It can also be related to a plasma protein loss. Possibly evidenced by: d. Edema formation e. Sudden weight gain f. Hemoconcentration g. Nausea & vomiting h. Epigastric pain i. Headache j. Visual changes k. Decreased urine output
  • 74. Ineffective Tissue Perfusion related to vasoconstriction of blood vessels It could be related to vasospasm of spiral arteries & relative hypovolemia. Possibly evidenced by: e. Changes in Fetal heart rate f. Reduced weight gain g. Premature delivery
  • 75. Nursing Interventions Woman with MILD PIH:  Monitor Antiplatelet Therapy  Promote Bed Rest  Promote Good Nutrition  Provide Emotional Support Woman with SEVERE PIH:  Support bed rest  Monitor maternal well-being  Monitor fetal well-being  Support a nutritious diet  Administer medications to prevent Eclampsia
  • 76. Woman with ECLAMPSIA: II. Patient that has tonic-clonic seizure:  Maintain a patent airway  Administer Oxygen face mask  Turn the woman in her side to prevent aspirations  Administer Magnesium Sulfate or diazepam via IV  Assess oxygenation via pulse oximeter

Editor's Notes

  1. loud noise can trigger a seizure, initiating eclampsia  to prevent injury if a seizure should occur  bright light can trigger seizures
  2. to detect any increase w/c can indicate worsening of the condition )  to assess for renal and liver function and the development of DIC, which often accompanies severe vasospasm  because she is at high risk for premature separation of the placenta and resulting hemorrhage
  3. monitor blood concentration, level will rise if INCREASED FLUID is leaving blood stream for interstitial tissue  edema  to monitor sx of arterial spasm, edema or hemorrhage  to evaluate tissue fluid retention  to allow accurate recording of output and comparison with intake.
  4. (peripheral vasodilator); used to decrease hypertension