Marine Derivatives: A Promising
Source of Nutraceuticals
CREDIT SEMINARCREDIT SEMINAR
SUBMITTED BY :-SUBMITTED BY :-
SMIT R. LENDESMIT R. LENDE
REGD. NO:-J4-01223-2013REGD. NO:-J4-01223-2013
DEPT. OF AQUACULTUREDEPT. OF AQUACULTURE
Content
introduction
 In modern Era of twenty one century the life style has significantly changes
with the tremendous increase in world population.
 Increased leisure and rise in purchasing power resulted in reduction in physical
activity.
 These change in life style had specific impact on food consumption patterns of
general public.
Cont…
 A shift towards consumption of food with high levels of sugar and saturated fats,
showed detrimental effects on health with course of time.
 This leads to sudden rise in chronic disease such as coronary heart diseases,
hypertension, obesity, cancer, diabetes, and osteoporosis.
Main causes of death in India….
Cont…
 Maintaining a healthy lifestyle is a basic need for most people.
 It is well known that good health is strongly associated with diet and many
other factors such as genetics, environment, lifestyle habits, and physical
activity.
 People are highly concerned about selecting healthy foods with a wide
range of medicinal values to reduce their risk of chronic diseases.
NUTRACEUTICALS: Let Food be Your Medicine
 The term “Nutraceutical” was coined from “Nutrition” & “Pharmaceutical” in 1989 by
Stephen DeFelice
A nutraceutical was defined as any substance that may be considered a food or a part of a food
and provides medical or health benefits including the prevention and treatment of disease
(Andlauer and Furst, 2002).
Role of neutraceuticals in prevention of illness
Classification of Nutraceuticals
 Nutraceuticals are nonspecific biological therapies used to promote wellness,
prevent malignant processes, and control symptoms.
 It is a broad umbrella term used to describe any product derived from food
sources that provides extra health benefits in addition to the basic nutritional
value found in foods.
 Phytochemicals and antioxidants are two specific types of nutraceuticals.
Cont…..
There are multiple different types of products that come under the
category of nutraceuticals:
Dietary supplements
Functional foods
 Medical foods
Difference between Functional food and
Nutraceutical
Growing demand for Nutrasuticals..
GLOBAL NUTRACEUTICAL MARKET - FOODS, BEVERAGES AND SUPPLEMENTS,
2006-2013 ($ MILLIONS)
( BCC Research )
Indian nutraceuticals market….
 In 2012, the Indian Nutraceutical market accounted for only about 1% of the global
nutraceuticals market.
 Given the changing demographics of the Indian population and increasing focus on
fitness and good health, the Nutraceutical market is being identified as a high potential
market in India.
 According to the report “
India Nutraceutical Market Forecast & Opportunities, 2017,” recently published
by TechSci Research, it is estimated that the Nutraceuticals market is set to grow
beyond USD 4.2 billion revenues by the end of 2017.
Need for Nutraceuticals
 Increased life expectancy, globally, has led to an increase in the incidence of
lifestyle (age related) diseases such as diabetes, high blood pressure and
cholesterol, obesity etc.
 As a result, there has been a significant increase in the deaths due to lifestyle
diseases worldwide.
 Consumers worldwide are looking to follow healthy lifestyles to obtain
optimum nutrition to keep these diseases at bay, leading to an increase in
nutraceutical consumption by health conscious consumers.
Life expectancy across regions, (World),
1970-2009
In spite of having a relatively lower
life expectancy, India has one of the
highest mortality rates for non-
communicable, age related diseases.
This trend can be witnessed across
almost all developing countries
Most consumers are well aware of the health benefits of foods, only 35 percent
were aware of the term nutraceuticals.
Health benefits of marine nutraceuticals
Marine nutraceuticals might have a positive effect on human health as
they can protect human body against damage by reactive oxygen
species (ROS)
which attack macromolecules such as membrane lipids, proteins, and
DNA and lead to many health disorders such as cancer, diabetes
mellitus, neurodegenerative and inflammatory diseases with severe
tissue injuries.
Cont…
Carotenoids are thought to be responsible for the beneficial
properties in preventing human diseases, including cardiovascular
diseases, cancer, and other chronic diseases.
marine-derived sterols have received much attention in the last few
years because of their cholesterol-lowering properties.
Marine algal-derived SPs exhibited various health-beneficial
biological activities such as anti-HIV-1, anticoagulant, and
anticancer activities
 omega-3 polyunsaturated fatty acids (PUFA) are produced in
phytoplanktons in the oceans and are then consumed by fish and
other marine species.
 The constituent fatty acids present in such oils include
eicosapentaenoic acid (EPA, 20:5 n-3), docosahexaenoic acid
(DHA, 22:6 n-3), and to a lesser extent docosapentaenoic acid
(DPA, 22:5 n-3) in different proportions, depending on the
species involved.
Fish oil
Cont ..
 Beneficial health effects of marine oils are manifold, and go beyond
those related to coronary heart disease (CHD), visual and cognitive
development, psychiatric conditions, inflammatory diseases, Crohn’s
disease, and type-2 diabetes, among others.
 The n-3 fatty acids, especially DHA, are known to dominate the fatty
acid profile of brain and retina lipids and play a major role in the
development of the fetus and infants, as well as the health status and
body requirements of pregnant and lactating women.
Some omega 3 rich products available in
market
Nutritional Value of Sea Lettuces
Seaweeds represent one of the most nutritious plant foods, and general
utilization of seaweeds in food products.
Sea lettuces comprise the genus Ulva, a group of edible green
seaweeds which is widely distributed along the coasts of the world’s
oceans and often found in the mid and upper tidal zones.
Some sea lettuces products available in
market
Chitin and chitosan
Chitin is recovered from processing discards of shrimp, crab, lobster,
and crayfish following deproteinization and demineralization.
The chitin so obtained may then be deacetylated to afford chitosan .
Depending on the duration of the deacylation process, the chitosan
produced may assume different viscosities and molecular weights.
Cont…
Chitosan has a variety of health benefits and may be employed in a
number of nutraceutical and healthrelated applications.
Chitosan derivatives may also be produced in order to obtain more
effective products for certain applications.
Food application of chitin and chitosan
Some Chitin based products available in
market
Abalone

Abalone is a commercially important marine “archeogastropod”
mollusk with characteristic single auriform shell under the family of
Haliotidae.
As a food, abalone has been in demand for a long time due to its rich
nutritional value, superior taste, and various other benefits to human
health.
Cont..
Among other mollusk species; hence, it is known as “the emperor of
the seashells,” “mother of shellfish,” or “ginseng in the ocean.
 There are 56 recognized abalone species that belong to the genus
Haliotis; however, it is believed that there could be more than 100
species of abalones.
Some Abalone based products available in
market
• Place of Origin: New Zealand
•The most Pure & Natural Environment in the world with No Air Pollution,
No Water Pollution, 100% Healthy and Clean!
•Abalone is favoured for its high nutrient content that has traditionally been
used to support eye health.
•Good Health Abalone Extract provides a concentrated source of more than
25 vitamins and minerals and is particularly rich in selenium,
magnesium and B12.
Shark cartilage
Shark cartilage, extracted from the fins and heads of sharks, is a type
of flexible connective tissue found in the animal’s skeletal system.
Traditionally, shark cartilage has been eaten as a food and health
supplement in the Far East.
Chondroitin sulphate, a bioactive component of shark cartilage, is a
typical mucopolysaccharide sulphate.
 It is mostly used as a base for cosmetics such as hand creams.
Cont..
shark liver oil exhibited bioactivity against cancer.
Shark liver oil is also known to contain a high proportion of squalene,
up to 50%.
Squalene is used in cosmetics as a skin softener and lubricant since low
levels are found in our normal skin oils.
Cartilade.
Shark cartilage has long been valued by traditional herbalists in China,
where it has been consumed for centuries as shark fin soup. Shark
cartilage contains mucopolysaccharides, a family of complex
carbohydrates including the now well-known chondroitin sulfate. It is an
excellent source of calcium and phosphorus.
Some Shark cartilage based products
available in market
Beneficial effects of marine bioactives on
the human cardiovascular system
Nutraceuticals produce in India
•Cadalmin Green Mussel extract contains 100%
natural marine bioactive anti-inflammatory ingredients
extracted from green mussel Perna viridis.
• The product is effective to combat arthritic pain and
inflammatory diseases in human beings, and is an
effective green alternative to synthetic non steroidal
anti-inflammatory drugs and other products available
in the market.
Cadalmin Green Algal extract 
•Cadalmin Green Algal extract contains a unique blend of
100% natural marine bioactive anti-inflammatory
ingredients extracted from selected seaweeds or marine
macroalgae with a patented ecofriendly “green” technology .
•The product is effective to combat arthritic pain and
inflammatory diseases in human beings.
• Patients suffering with chronic joint pain and arthritis
clinical trial-based studies revealed that more than 98% of
the respondents were satisfied with the product with about
70-85% relief in joint pain and arthritis.
Conclusion
 With so many new species of marine resources still to be
discovered, the potential for new marine-derived
bioactive nutraceuticals is immense with beneficial
effects on human health, and the food industry is poised
for accelerated development in the near future.
 Marine resources have been well recognized for their
biologically active substances with a great potential to
be used as nutraceuticals.
Cont…
 Moreover, much attention has been paid
recently by the consumers toward healthy
lifestyle with natural bioactive ingredients.
 Recent studies have provided evidence that
marine-derived bioactive nutraceuticals play a
vital role in human health.
The physical body is the product of diet and sensory inputs (i.e.,
lifestyle).
Similarly, all ailments are the product of faulty dietetics and lifestyle.
Wholesome and unwholesome diets and lifestyles are fundamentals of
health and disease….
Caraka Samhita Sutrasthana 28:45
Thank you

Marine derived nutraceuticals and its potential use

  • 1.
    Marine Derivatives: APromising Source of Nutraceuticals CREDIT SEMINARCREDIT SEMINAR SUBMITTED BY :-SUBMITTED BY :- SMIT R. LENDESMIT R. LENDE REGD. NO:-J4-01223-2013REGD. NO:-J4-01223-2013 DEPT. OF AQUACULTUREDEPT. OF AQUACULTURE
  • 2.
  • 3.
    introduction  In modernEra of twenty one century the life style has significantly changes with the tremendous increase in world population.  Increased leisure and rise in purchasing power resulted in reduction in physical activity.  These change in life style had specific impact on food consumption patterns of general public.
  • 4.
    Cont…  A shifttowards consumption of food with high levels of sugar and saturated fats, showed detrimental effects on health with course of time.  This leads to sudden rise in chronic disease such as coronary heart diseases, hypertension, obesity, cancer, diabetes, and osteoporosis.
  • 5.
    Main causes ofdeath in India….
  • 6.
    Cont…  Maintaining ahealthy lifestyle is a basic need for most people.  It is well known that good health is strongly associated with diet and many other factors such as genetics, environment, lifestyle habits, and physical activity.  People are highly concerned about selecting healthy foods with a wide range of medicinal values to reduce their risk of chronic diseases.
  • 7.
    NUTRACEUTICALS: Let Foodbe Your Medicine  The term “Nutraceutical” was coined from “Nutrition” & “Pharmaceutical” in 1989 by Stephen DeFelice A nutraceutical was defined as any substance that may be considered a food or a part of a food and provides medical or health benefits including the prevention and treatment of disease (Andlauer and Furst, 2002).
  • 8.
    Role of neutraceuticalsin prevention of illness
  • 9.
    Classification of Nutraceuticals Nutraceuticals are nonspecific biological therapies used to promote wellness, prevent malignant processes, and control symptoms.  It is a broad umbrella term used to describe any product derived from food sources that provides extra health benefits in addition to the basic nutritional value found in foods.  Phytochemicals and antioxidants are two specific types of nutraceuticals.
  • 10.
    Cont….. There are multipledifferent types of products that come under the category of nutraceuticals: Dietary supplements Functional foods  Medical foods
  • 11.
    Difference between Functionalfood and Nutraceutical
  • 12.
    Growing demand forNutrasuticals.. GLOBAL NUTRACEUTICAL MARKET - FOODS, BEVERAGES AND SUPPLEMENTS, 2006-2013 ($ MILLIONS) ( BCC Research )
  • 13.
    Indian nutraceuticals market…. In 2012, the Indian Nutraceutical market accounted for only about 1% of the global nutraceuticals market.  Given the changing demographics of the Indian population and increasing focus on fitness and good health, the Nutraceutical market is being identified as a high potential market in India.  According to the report “ India Nutraceutical Market Forecast & Opportunities, 2017,” recently published by TechSci Research, it is estimated that the Nutraceuticals market is set to grow beyond USD 4.2 billion revenues by the end of 2017.
  • 14.
    Need for Nutraceuticals Increased life expectancy, globally, has led to an increase in the incidence of lifestyle (age related) diseases such as diabetes, high blood pressure and cholesterol, obesity etc.  As a result, there has been a significant increase in the deaths due to lifestyle diseases worldwide.  Consumers worldwide are looking to follow healthy lifestyles to obtain optimum nutrition to keep these diseases at bay, leading to an increase in nutraceutical consumption by health conscious consumers.
  • 15.
    Life expectancy acrossregions, (World), 1970-2009 In spite of having a relatively lower life expectancy, India has one of the highest mortality rates for non- communicable, age related diseases. This trend can be witnessed across almost all developing countries
  • 16.
    Most consumers arewell aware of the health benefits of foods, only 35 percent were aware of the term nutraceuticals.
  • 17.
    Health benefits ofmarine nutraceuticals Marine nutraceuticals might have a positive effect on human health as they can protect human body against damage by reactive oxygen species (ROS) which attack macromolecules such as membrane lipids, proteins, and DNA and lead to many health disorders such as cancer, diabetes mellitus, neurodegenerative and inflammatory diseases with severe tissue injuries.
  • 18.
    Cont… Carotenoids are thoughtto be responsible for the beneficial properties in preventing human diseases, including cardiovascular diseases, cancer, and other chronic diseases. marine-derived sterols have received much attention in the last few years because of their cholesterol-lowering properties. Marine algal-derived SPs exhibited various health-beneficial biological activities such as anti-HIV-1, anticoagulant, and anticancer activities
  • 19.
     omega-3 polyunsaturatedfatty acids (PUFA) are produced in phytoplanktons in the oceans and are then consumed by fish and other marine species.  The constituent fatty acids present in such oils include eicosapentaenoic acid (EPA, 20:5 n-3), docosahexaenoic acid (DHA, 22:6 n-3), and to a lesser extent docosapentaenoic acid (DPA, 22:5 n-3) in different proportions, depending on the species involved. Fish oil
  • 20.
    Cont ..  Beneficialhealth effects of marine oils are manifold, and go beyond those related to coronary heart disease (CHD), visual and cognitive development, psychiatric conditions, inflammatory diseases, Crohn’s disease, and type-2 diabetes, among others.  The n-3 fatty acids, especially DHA, are known to dominate the fatty acid profile of brain and retina lipids and play a major role in the development of the fetus and infants, as well as the health status and body requirements of pregnant and lactating women.
  • 21.
    Some omega 3rich products available in market
  • 22.
    Nutritional Value ofSea Lettuces Seaweeds represent one of the most nutritious plant foods, and general utilization of seaweeds in food products. Sea lettuces comprise the genus Ulva, a group of edible green seaweeds which is widely distributed along the coasts of the world’s oceans and often found in the mid and upper tidal zones.
  • 27.
    Some sea lettucesproducts available in market
  • 28.
    Chitin and chitosan Chitinis recovered from processing discards of shrimp, crab, lobster, and crayfish following deproteinization and demineralization. The chitin so obtained may then be deacetylated to afford chitosan . Depending on the duration of the deacylation process, the chitosan produced may assume different viscosities and molecular weights.
  • 31.
    Cont… Chitosan has avariety of health benefits and may be employed in a number of nutraceutical and healthrelated applications. Chitosan derivatives may also be produced in order to obtain more effective products for certain applications.
  • 32.
    Food application ofchitin and chitosan
  • 33.
    Some Chitin basedproducts available in market
  • 34.
    Abalone  Abalone is acommercially important marine “archeogastropod” mollusk with characteristic single auriform shell under the family of Haliotidae. As a food, abalone has been in demand for a long time due to its rich nutritional value, superior taste, and various other benefits to human health.
  • 35.
    Cont.. Among other molluskspecies; hence, it is known as “the emperor of the seashells,” “mother of shellfish,” or “ginseng in the ocean.  There are 56 recognized abalone species that belong to the genus Haliotis; however, it is believed that there could be more than 100 species of abalones.
  • 36.
    Some Abalone basedproducts available in market • Place of Origin: New Zealand •The most Pure & Natural Environment in the world with No Air Pollution, No Water Pollution, 100% Healthy and Clean! •Abalone is favoured for its high nutrient content that has traditionally been used to support eye health. •Good Health Abalone Extract provides a concentrated source of more than 25 vitamins and minerals and is particularly rich in selenium, magnesium and B12.
  • 37.
    Shark cartilage Shark cartilage,extracted from the fins and heads of sharks, is a type of flexible connective tissue found in the animal’s skeletal system. Traditionally, shark cartilage has been eaten as a food and health supplement in the Far East. Chondroitin sulphate, a bioactive component of shark cartilage, is a typical mucopolysaccharide sulphate.  It is mostly used as a base for cosmetics such as hand creams.
  • 38.
    Cont.. shark liver oilexhibited bioactivity against cancer. Shark liver oil is also known to contain a high proportion of squalene, up to 50%. Squalene is used in cosmetics as a skin softener and lubricant since low levels are found in our normal skin oils.
  • 39.
    Cartilade. Shark cartilage haslong been valued by traditional herbalists in China, where it has been consumed for centuries as shark fin soup. Shark cartilage contains mucopolysaccharides, a family of complex carbohydrates including the now well-known chondroitin sulfate. It is an excellent source of calcium and phosphorus.
  • 40.
    Some Shark cartilagebased products available in market
  • 41.
    Beneficial effects ofmarine bioactives on the human cardiovascular system
  • 42.
    Nutraceuticals produce inIndia •Cadalmin Green Mussel extract contains 100% natural marine bioactive anti-inflammatory ingredients extracted from green mussel Perna viridis. • The product is effective to combat arthritic pain and inflammatory diseases in human beings, and is an effective green alternative to synthetic non steroidal anti-inflammatory drugs and other products available in the market.
  • 43.
    Cadalmin Green Algalextract  •Cadalmin Green Algal extract contains a unique blend of 100% natural marine bioactive anti-inflammatory ingredients extracted from selected seaweeds or marine macroalgae with a patented ecofriendly “green” technology . •The product is effective to combat arthritic pain and inflammatory diseases in human beings. • Patients suffering with chronic joint pain and arthritis clinical trial-based studies revealed that more than 98% of the respondents were satisfied with the product with about 70-85% relief in joint pain and arthritis.
  • 44.
    Conclusion  With somany new species of marine resources still to be discovered, the potential for new marine-derived bioactive nutraceuticals is immense with beneficial effects on human health, and the food industry is poised for accelerated development in the near future.  Marine resources have been well recognized for their biologically active substances with a great potential to be used as nutraceuticals.
  • 45.
    Cont…  Moreover, muchattention has been paid recently by the consumers toward healthy lifestyle with natural bioactive ingredients.  Recent studies have provided evidence that marine-derived bioactive nutraceuticals play a vital role in human health.
  • 46.
    The physical bodyis the product of diet and sensory inputs (i.e., lifestyle). Similarly, all ailments are the product of faulty dietetics and lifestyle. Wholesome and unwholesome diets and lifestyles are fundamentals of health and disease…. Caraka Samhita Sutrasthana 28:45
  • 47.

Editor's Notes