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Topic: NUTRACEUTICALS
CONTENT
HISTORY

INTRODUCTION

CONCLUSION

BIBLIOGRAPHY

2
HISTORY
• The Greek physician Hippocrates, often known as the

“father of medicine” said “let food be your medicine”.
The Philosophy behind is:

“Focus on Prevention”
• The term "Nutraceutical" was coined by combining the

terms "Nutrition" and "Pharmaceutical" in 1989 by

Dr. Stephen DeFelice.

3
• According

to Dr. DeFelice , “Nutraceutical is any

substance that is a food or a part of food that provides
medicinal or health benefits including the prevention and

treatment of disease.”[1]
• Health ministry of Canada defines it “As a product isolated

or purified from the food generally sold in medicinal form
not assisted with food and demonstrated to have a
physiological benefit and provide protection against
chronic disease.”[2]

4
Introduction
• The

Plants or herbs particularly Fruits and

Vegetables are the cheapest and most common store
of Nutrients i.e:• Carbohydrates
• Proteins
• Vitamins
• Minerals
• And essential amino acids

5
6
Classification of Nutraceuticals
1. Potential Nutraceuticals - one which has promising

approach towards particular health or medicinal benefit.

2. Established Nutraceuticals – A Potential Nutraceutical

becomes Established Nutraceutical only after there are
sufficient clinical data to demonstrate such a benefit.

7
Classification based on source

1. Plants

- Tomato, Garlic, Momordica

2. Animals

- Shark liver oil, Cod liver oil

3. Minerals

- Calcium, Magnesium, Phosphorous

4. Microorganism - Bifidobacterium, Lactobacilli

8
Raaz et al. 2011.

Nutraceuticals mainly consists of :
1. Nutrients:

Substances

which

have

established

Nutritional functions e.g. Vitamins, Minerals, Amino
Acids, Fatty acids, etc.
2. Herbals/ Phytochemicals: Herbs or Botanical products

3. Dietary

Supplements:

Probiotics, Prebiotics, Antioxidents, Enzymes, etc.

9
1. NUTRIENTS
Most common
Nutrients used as

Nutraceutical are:
• Minerals and

Vitamins.
• or in combination of

both.
• or in combination

with other
antioxidants
10
Minerals

11
2.Herbs

12
13
Avrelija and Walter , 2010

3. Dietary supplements:
 Probiotics-

Live

microorganisms

which,

when

administered in adequate amounts, confer a health
benefit on the host
 Species of Lactobacillus
 Yeast Saccharomyces Cerevisiae
 some E. Coli and Bacillus species are also used as

probiotics
• Probiotics have been shown to have applications in

alleviating
symptoms
of
allergies, cancer, AIDS, respiratory and urinary tract
infections.
14
Manage
Lactose
Intolerance
Shorten
Duration of
Intestinal
Infections

Treat Diarrhea

Potential
Benefits of
Probiotics

Reduce Bladder
and Urinary
Tract Infections

Improve
Symptoms of
Irritable Bowel
Syndrome
15
 Prebiotics-

Nondigestible substances that provide a

beneficial physiological effect for the host by selectively
stimulating the favorable growth of a limited number of

indigenous bacteria.
Commonly known prebiotics are:
• Oligofructose .
• Inulin
• Galacto-oligosaccharides
• Lactulose

16
Areas covered by Nutraceuticals :
All therapeutic areas such as,
1.

Anti- Arthritic (Rheumatoid Arthritis)

2.

Sleeping disorders

3.

Digestion problems

4.

Prevention of certain cancers (Colorectal cancer)

5.

Osteoporosis

6.

Blood pressure

7.

Cholesterol lowering (garlic)

8.

Neurological disorders (Autism)

9.

Diabetes etc..
17
Dietary polyphenols as potential nutraceuticals in management of diabetes
by Bahadoran et al. 2013.

18
Mahima et al. 2013

23/12/2013

M.Tech Seminar- I Dept. of Chemical Engg.

19
20
23/12/2013

M.Tech Seminar- I Dept. of Chemical Engg.

21
Nutraceuticals may range in the form of :
• isolated nutrients,
• dietary supplements,
• genetically engineered “designer” food,
• herbal products,

• and processed products such as cereals, soups, and

beverages

22
Sarin et al. 2012.

23
24
Future Developments of Nutraceuticals

25
Conclusion
Nutraceuticals may be beneficial to our health but we are still

learning about their benefits and possible harmful effects.
Government regulatory bodies also face challenges in this new

category of health products, which lies between foods and

drugs.
Health professional , Nutritionists and regulatory toxicologist

should

strategically

work

together

to

plan

appropriate

regulation to provide ultimate health and therapeutic benefit to
mankind.
26
Bibliography
1.

Brower V. “Nutraceuticals: poised for a healthy slice of the healthcare market”
Nat. Biotechnol.1998, 16, 728-731.

2.

http://www.hc-sc.gc.ca/sr-sr/biotech/about.apropor/gloss-eng.php(assessed on 23
sep 2010)

3.

Raaz .M; Priyanka S; Bina R; Chauhan AK. “Healthy living with Nutraceuticals”

International Research Journal of Pharmacy 2011,2(12),12-14
4.

Bahadoran Z; Parvin M; Fereidoun A. “Dietary polyphenols as potential
Nutraceuticals in management of diabetes” Journal of Diabetes & Metabolic
Disorders 2013,12:43

5.

Mahima ; Amit K; Ruchi T; K Karthik” Nutraceuticals from fruits and vegetables at
glance” . Journal of Biological sciences 2013,13(3):38-47
27
6.

Avrelija C and Walter C “ The role of functional foods, Nutraceuticals and food
suplements

in

intestinal

health”

Nutrients

2010,

2,

611-625;

doi:

10.3390/nu2060611
7.

Sarin R; Sharma M; Singh R; Kumar S ” Nutraceuticals” International Research
Journal of Pharmacy 2012, 3 (4)

8.

Prasuram RR ; Rawat B ; Thangavel S “ Nutraaceuticals : An Area of

Tremendous Scope” International Research Journal of Pharmacy 2011, 2(2) 410415

28
29

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Nutraceuticals= "Nutrition" and "Pharmaceutical"

  • 3. HISTORY • The Greek physician Hippocrates, often known as the “father of medicine” said “let food be your medicine”. The Philosophy behind is: “Focus on Prevention” • The term "Nutraceutical" was coined by combining the terms "Nutrition" and "Pharmaceutical" in 1989 by Dr. Stephen DeFelice. 3
  • 4. • According to Dr. DeFelice , “Nutraceutical is any substance that is a food or a part of food that provides medicinal or health benefits including the prevention and treatment of disease.”[1] • Health ministry of Canada defines it “As a product isolated or purified from the food generally sold in medicinal form not assisted with food and demonstrated to have a physiological benefit and provide protection against chronic disease.”[2] 4
  • 5. Introduction • The Plants or herbs particularly Fruits and Vegetables are the cheapest and most common store of Nutrients i.e:• Carbohydrates • Proteins • Vitamins • Minerals • And essential amino acids 5
  • 6. 6
  • 7. Classification of Nutraceuticals 1. Potential Nutraceuticals - one which has promising approach towards particular health or medicinal benefit. 2. Established Nutraceuticals – A Potential Nutraceutical becomes Established Nutraceutical only after there are sufficient clinical data to demonstrate such a benefit. 7
  • 8. Classification based on source 1. Plants - Tomato, Garlic, Momordica 2. Animals - Shark liver oil, Cod liver oil 3. Minerals - Calcium, Magnesium, Phosphorous 4. Microorganism - Bifidobacterium, Lactobacilli 8
  • 9. Raaz et al. 2011. Nutraceuticals mainly consists of : 1. Nutrients: Substances which have established Nutritional functions e.g. Vitamins, Minerals, Amino Acids, Fatty acids, etc. 2. Herbals/ Phytochemicals: Herbs or Botanical products 3. Dietary Supplements: Probiotics, Prebiotics, Antioxidents, Enzymes, etc. 9
  • 10. 1. NUTRIENTS Most common Nutrients used as Nutraceutical are: • Minerals and Vitamins. • or in combination of both. • or in combination with other antioxidants 10
  • 13. 13
  • 14. Avrelija and Walter , 2010 3. Dietary supplements:  Probiotics- Live microorganisms which, when administered in adequate amounts, confer a health benefit on the host  Species of Lactobacillus  Yeast Saccharomyces Cerevisiae  some E. Coli and Bacillus species are also used as probiotics • Probiotics have been shown to have applications in alleviating symptoms of allergies, cancer, AIDS, respiratory and urinary tract infections. 14
  • 15. Manage Lactose Intolerance Shorten Duration of Intestinal Infections Treat Diarrhea Potential Benefits of Probiotics Reduce Bladder and Urinary Tract Infections Improve Symptoms of Irritable Bowel Syndrome 15
  • 16.  Prebiotics- Nondigestible substances that provide a beneficial physiological effect for the host by selectively stimulating the favorable growth of a limited number of indigenous bacteria. Commonly known prebiotics are: • Oligofructose . • Inulin • Galacto-oligosaccharides • Lactulose 16
  • 17. Areas covered by Nutraceuticals : All therapeutic areas such as, 1. Anti- Arthritic (Rheumatoid Arthritis) 2. Sleeping disorders 3. Digestion problems 4. Prevention of certain cancers (Colorectal cancer) 5. Osteoporosis 6. Blood pressure 7. Cholesterol lowering (garlic) 8. Neurological disorders (Autism) 9. Diabetes etc.. 17
  • 18. Dietary polyphenols as potential nutraceuticals in management of diabetes by Bahadoran et al. 2013. 18
  • 19. Mahima et al. 2013 23/12/2013 M.Tech Seminar- I Dept. of Chemical Engg. 19
  • 20. 20
  • 21. 23/12/2013 M.Tech Seminar- I Dept. of Chemical Engg. 21
  • 22. Nutraceuticals may range in the form of : • isolated nutrients, • dietary supplements, • genetically engineered “designer” food, • herbal products, • and processed products such as cereals, soups, and beverages 22
  • 23. Sarin et al. 2012. 23
  • 24. 24
  • 25. Future Developments of Nutraceuticals 25
  • 26. Conclusion Nutraceuticals may be beneficial to our health but we are still learning about their benefits and possible harmful effects. Government regulatory bodies also face challenges in this new category of health products, which lies between foods and drugs. Health professional , Nutritionists and regulatory toxicologist should strategically work together to plan appropriate regulation to provide ultimate health and therapeutic benefit to mankind. 26
  • 27. Bibliography 1. Brower V. “Nutraceuticals: poised for a healthy slice of the healthcare market” Nat. Biotechnol.1998, 16, 728-731. 2. http://www.hc-sc.gc.ca/sr-sr/biotech/about.apropor/gloss-eng.php(assessed on 23 sep 2010) 3. Raaz .M; Priyanka S; Bina R; Chauhan AK. “Healthy living with Nutraceuticals” International Research Journal of Pharmacy 2011,2(12),12-14 4. Bahadoran Z; Parvin M; Fereidoun A. “Dietary polyphenols as potential Nutraceuticals in management of diabetes” Journal of Diabetes & Metabolic Disorders 2013,12:43 5. Mahima ; Amit K; Ruchi T; K Karthik” Nutraceuticals from fruits and vegetables at glance” . Journal of Biological sciences 2013,13(3):38-47 27
  • 28. 6. Avrelija C and Walter C “ The role of functional foods, Nutraceuticals and food suplements in intestinal health” Nutrients 2010, 2, 611-625; doi: 10.3390/nu2060611 7. Sarin R; Sharma M; Singh R; Kumar S ” Nutraceuticals” International Research Journal of Pharmacy 2012, 3 (4) 8. Prasuram RR ; Rawat B ; Thangavel S “ Nutraaceuticals : An Area of Tremendous Scope” International Research Journal of Pharmacy 2011, 2(2) 410415 28
  • 29. 29

Editor's Notes

  1. The concept of food as medicine is an ancient one, noticeably strengthened byreports from contemporary medical research and practice. The Greek physicianHippocrates, often known as the “father of medicine” enunciated this belief severalcenturies ago, as “let food be your medicine”. The term "Nutraceutical" was coined by combining the terms "Nutrition" and "Pharmaceutical" in 1989 by Dr Stephen DeFelice
  2. polyphenols (hydrolyzable and condensedtannins)Green tea polyphenols, mainly catechins and epicatechins