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Management 
of 
Behavioural 
Crisis 
in 
Children 
with 
Developmental 
Issues 
Dr. 
Norharlina 
Bahar 
Child 
& 
Adolescent 
Psychiatrist 
Hospital 
Selayang 
29 
August 
2014
Outline 
• What? 
• Causes 
• PrevenJon 
• Management: 
– Before 
– In 
the 
midst 
– ALer 
• Pharmacotherapy 
• Causes 
of 
ID 
and 
behavioural 
paNern 
2
What 
is 
behavioural 
crisis? 
• In 
full 
meltdown 
mode 
• The 
child 
is 
not 
capable 
of 
reasoning, 
being 
redirected, 
or 
learning 
replacement 
skills. 
• One 
off 
or 
frequently 
or 
ongoing? 
3
Challenging 
Behaviour 
in 
Children 
with 
Developmental 
Issues 
• 2 
– 
3 
x 
more 
common 
(CorbeN, 
1979; 
Richardson 
1979; 
Eifeld, 
1995; 
Tonge, 
1998) 
• AgitaJon 
• Aggression 
• DisrupJve 
behaviour 
• Self-­‐injurous 
behaviour 
• A 
significant 
change 
in 
funcJon 
(loss 
of 
interests, 
withdrawal 
from 
family, 
etc.) 
• School 
expulsion 
and/or 
an 
inability 
to 
leave 
the 
home. 
4
PrevenJon 
• The 
most 
effecJve 
way 
to 
manage 
challenging 
behaviours 
is 
to 
try 
prevenJng 
them 
from 
happening 
rather 
than 
just 
focusing 
on 
what 
to 
do 
when 
or 
aLer 
the 
behaviour 
occurs. 
• Learn 
skills 
to 
help 
anJcipate 
and 
turn 
around 
an 
escalaJng 
situaJon. 
5
PosiJve 
Behaviour 
Support 
Approach 
• Consider 
the 
purpose 
or 
‘why’ 
of 
the 
behaviour 
• Focus 
on 
prevenJng 
the 
behaviour 
from 
happening 
by 
avoiding 
or 
changing 
the 
circumstances 
that 
trigger 
the 
behaviour 
• Teach 
new 
behaviours 
or 
skills 
to 
replace 
the 
challenging 
behaviour 
6
What 
purpose 
(or 
FuncJon) 
does 
challenging 
behaviour 
serve? 
• All 
behaviour 
happens 
for 
a 
reason 
• Health 
problems 
-­‐ 
may 
cause 
challenging 
behaviour 
or 
make 
it 
worse. 
• Common 
reasons 
are: 
– Interact 
with 
someone 
– Social 
aNenJon: 
e.g. 
shouJng 
– To 
get 
something: 
A 
person 
may 
learn 
behaviours 
that 
get 
them 
things 
they 
want. 
– Escape 
or 
avoid 
a 
demand/ 
request/ 
situaJon/ 
object/ 
person 
– Sensory: 
to 
get/ 
avoid 
sensory 
sJmulaJon 
i.e. 
rocking, 
humming 
– Get 
some 
control 
or 
predictability 
over 
their 
day 
or 
the 
acJvity 
– Reduce 
their 
arousal 
and 
or 
anxiety. 
7
FuncJonal 
Assessment 
• To 
find 
out 
the 
exact 
causes 
of 
a 
person’s 
behaviour 
• Keep 
a 
record: 
1. DescripJon 
of 
the 
behaviour 
i.e. 
exactly 
what 
happens 
2. Early 
warning 
signs, 
e.g. 
becoming 
red 
in 
the 
face 
3. What 
happens 
before 
the 
behaviour, 
e.g. 
does 
something 
trigger 
the 
behaviours? 
Noisy 
environment? 
Being 
told 
no? 
etc. 
4. What 
happens 
aLer 
the 
event, 
i.e. 
what 
is 
the 
person 
gejng 
or 
not 
gejng 
from 
the 
behaviour 
that 
makes 
them 
do 
it 
again? 
8
Have 
a 
Crisis 
Plan 
• PreparaJon 
and 
strategies 
for 
coping 
and 
staying 
safe 
in 
these 
situaJons 
• To 
be 
developed 
by 
family 
& 
the 
treaJng 
team 
9
A 
well-­‐designed 
plan 
includes 
1. Defined 
sejng 
events, 
triggers 
or 
signs 
that 
a 
crisis 
situaJon 
might 
develop 
2. Tools 
and 
strategies 
for 
keeping 
the 
individual 
and 
those 
around 
him 
safe 
in 
any 
sejng 
(school, 
home, 
community) 
3. IntervenJon 
steps 
and 
procedures 
promoJng 
de-­‐escalaJon 
that 
are 
paired 
at 
each 
level 
with 
increasing 
levels 
of 
agitaJon 
4. Lists 
of 
things 
to 
do 
and 
NOT 
to 
do 
specific 
to 
the 
needs, 
history 
& 
fears 
of 
the 
individual 
5. Hands 
on 
training 
and 
pracJce 
for 
caregivers 
6. ConJnued 
re-­‐evaluaJon 
of 
the 
effecJveness 
of 
the 
plan 
7. Knowledge 
of 
facility 
if 
hospitalizaJon 
needed 
8. Maintain 
safety 
first 
and 
foremost. 
This 
is 
not 
the 
Jme 
to 
teach, 
make 
demands, 
or 
to 
shape 
behavior. 
10
Ways 
to 
Calm 
an 
EscalaJng 
SituaJon 
• Be 
on 
alert 
for 
triggers 
and 
warning 
signs. 
• Try 
to 
reduce 
stressors 
by 
removing 
distracJng 
elements, 
going 
to 
a 
less 
stressful 
place 
or 
providing 
a 
calming 
acJvity 
or 
object. 
• Remain 
calm, 
as 
his 
behavior 
is 
likely 
to 
trigger 
emoJons 
in 
you. 
• Be 
gentle 
and 
paJent. 
• Give 
him 
space. 
• Provide 
clear 
direcJons 
and 
use 
simple 
language. 
• Focus 
on 
returning 
to 
a 
calm 
state 
by 
allowing 
Jme 
in 
a 
quiet, 
relaxaJon-­‐promoJng 
acJvity. 
• Praise 
aNempts 
to 
self-­‐regulate 
and 
the 
use 
of 
strategies 
such 
as 
deep 
breathing. 
• Discuss 
the 
situaJon 
or 
teach 
alternate 
and 
more 
appropriate 
responses 
once 
calm 
has 
been 
achieved. 
11
In 
the 
midst 
of 
a 
Crisis 
SituaJon 
• Remain 
as 
calm 
as 
possible 
• Assess 
the 
severity 
of 
the 
situaJon 
• Follow 
the 
Crisis 
Plan 
and 
focus 
on 
safety 
• Determine 
whom 
to 
contact 
• Dial 
999 
for 
an 
emergency 
• Remember: 
this 
is 
not 
a 
‘teachable’ 
moment. 
12
• Consider 
the 
safety 
of 
your 
child 
& 
those 
around 
them: 
– can 
you 
remove 
your 
child 
from 
the 
situaJon 
safely? 
– do 
you 
need 
to 
remove 
yourself 
and 
other 
family 
members 
from 
the 
room 
or 
situaJon? 
– do 
you 
need 
to 
remove 
items 
from 
the 
environment 
or 
room 
that 
could 
be 
unsafe? 
• Consider 
the 
language 
you 
use 
with 
your 
child 
to 
avoid 
escala7on: 
– avoid 
talking 
as 
much 
as 
possible 
(stressful 
to 
have 
to 
work 
out 
what 
your 
words 
mean) 
– Use 
short, 
simple 
instrucJons 
if 
needed 
(include 
a 
visual 
clue 
eg. 
Opening 
door 
to 
show 
your 
child 
they 
can 
go 
outside 
to 
calm) 
– use 
a 
calm 
even 
voice. 
13
• Try 
to 
regain 
calm 
as 
quickly 
as 
possible 
by: 
– What 
will 
help 
the 
child 
calm 
as 
quickly 
as 
possible 
(Jme 
alone, 
access 
to 
an 
acJvity 
or 
item 
he/she 
likes 
that 
is 
calming) 
– What 
will 
help 
you 
calm 
as 
quickly 
as 
possible 
(leaving 
the 
room, 
gejng 
other 
family 
members 
safe, 
gejng 
back-­‐up) 
– Allow 
lots 
of 
Jme 
for 
recovery 
14
Challenges 
for 
Medical 
Professionals 
• Listen 
to 
the 
caregiver 
and 
the 
paJent 
to 
the 
extent 
possible. 
They're 
very 
unique 
in 
how 
they 
interact. 
• Do 
not 
think 
that 
we 
know 
beNer. 
• Aim 
to 
least 
restricJve 
care. 
• Family: 
be 
prepared 
to 
advocate 
yourself 
15
Physical 
Restraints, 
Seclusion 
& 
Rapid 
TranquillizaJon 
• When 
behaviors 
pose 
a 
risk 
of 
physical 
harm 
to 
the 
individual 
or 
others, 
a 
brief 
intervenJon 
are 
someJmes 
necessary 
to 
maintain 
safety. 
• Physical 
restraints 
-­‐ 
immobilizing 
or 
reducing 
the 
ability 
of 
an 
individual 
to 
move 
their 
arms, 
legs, 
body 
freely. 
• Seclusion 
-­‐ 
pujng 
the 
individual 
briefly 
in 
a 
room 
by 
himself 
to 
‘calm 
down’. 
16
Physical 
Restraints, 
Seclusion 
& 
Rapid 
TranquillizaJon 
(cont) 
• As 
last 
resort 
and 
when 
less 
restricJve 
methods 
are 
not 
effecJve 
or 
feasible. 
• Improper 
use 
can 
have 
serious 
consequences 
physically 
and 
emoJonally 
• Must 
take 
place 
within 
the 
legal 
framework 
ie. 
Consent 
or 
Mental 
Health 
Act 
17
Rapid 
TranquillizaJon 
• The 
aim 
is 
to 
achieve 
a 
state 
of 
calm 
sufficient 
to 
minimize 
the 
risk 
posed 
to 
the 
individual 
or 
to 
others. 
• Rapid 
tranquillisaJon 
with 
intramuscular 
or 
intravenous 
injecJons 
should 
only 
be 
used 
in 
healthcare 
sejngs 
with 
appropriate 
resuscitaJons 
need. 
18
Assessment 
• History 
• Previous 
hx 
of 
anJpsychoJc? 
Non-­‐drug 
approach 
• de-­‐escalaJon 
techniques, 
e.g. 
talking 
down, 
distracJon, 
Jme 
out 
• Inform 
paJent/ 
carer 
re 
medicaJon 
Oral 
• Lorazepam 
0.5 
-­‐ 
2mg 
• Olanzapine 
Zydis 
2.5 
mg 
– 
5mg 
• Risperidone 
0.5 
– 
1mg 
IV/IM 
• (Lorazepam) 
• Midazolam 
2.5 
– 
15 
mg 
• Haloperidol 
2.5 
– 
10 
mg 
Monitoring 
& 
Nursing 
• Vital 
signs 
• Low 
sJmulus 
environment 
Repeat 
• Wait 
at 
least 
30 
minutes 
19 
Maudley 
Guideline, 
2012, 
Byrne, 
2012; 
Heyman 
2003; 
NICE 
2006
De-­‐escalaJon 
• Maintain 
adequate 
distance. 
Respect 
personal 
space 
• Do 
not 
be 
provocaJve. 
• Ensure 
the 
environment 
is 
conducive 
for 
calmness. 
• Be 
calm 
& 
self-­‐assured, 
use 
non-­‐threatening, 
non-­‐verbal 
communicaJon. 
• Be 
concise, 
use 
repeJJon. 
• Explained 
intenJon, 
set 
clear 
limits. 
• Offer 
choices 
20
The 
Use 
of 
MedicaJon 
• Aimed 
at 
target 
symptoms 
eg. 
to 
achieve 
state 
of 
calm; 
paJent 
will 
hit 
others 
less 
frequently; 
psychoJc 
symptoms; 
irritability 
• Comprehensive 
assessment 
of 
the 
individual's 
emoJonal 
and 
behavioural 
disturbance 
and 
assessment 
of 
the 
efficacy 
of 
all 
previous 
modes 
of 
treatment. 
• Issue 
of 
informed 
consent 
& 
legal 
maNer 
• Should 
be 
integrated 
with 
other 
concurrent 
treatments. 
MedicaJon 
alone 
to 
is 
not 
sufficient. 
21
The 
Use 
of 
MedicaJon 
(cont) 
• SomeJmes 
unrealisJc 
demands 
to 
solve 
the 
problem 
by 
prescribing 
medicaJon. 
• Children 
with 
developmental 
issues 
are 
more 
vulnerable 
for 
side-­‐effects. 
22
Pharmacotherapy 
• Risperidone 
-­‐ 
effecJve 
and 
well 
tolerated 
for 
the 
treatment 
of 
agitaJon, 
aggression, 
or 
self-­‐ 
injurious 
behavior 
in 
children 
with 
ASD 
(McCracken 
2002, 
Davies 
2006) 
& 
ID 
(Unwin 
2011, 
DeDyn 
2006) 
• Aripiprazole 
is 
effecJve 
for 
irritability 
in 
children 
with 
ASD 
(Ching, 
2012) 
• Off-­‐label 
use: 
QueJapine, 
Olanzapine, 
Paliperidone 
(Golubchik 
2011, 
SJgler 
2012, 
Hollander 
2010) 
23
Pharmacotherapy 
(cont) 
• SSRI 
ie 
sertraline, 
fluvoxamine 
: 
comorbid 
depression, 
OCD, 
anxiety 
(Hellings 
1996, 
Campbell 
1995) 
• Benzodiazepines 
: 
short 
term, 
anxiety. 
Paradoxical 
effect 
(Barron, 
1985) 
• Valproate 
: 
mood 
lability, 
irritability, 
aggression 
(Kastner 
1990) 
• SJmulant 
: 
comorbid 
ADHD 
(Arnold 
1998, 
Handen 
1999) 
24
Causes 
of 
ID 
& 
Behaviour 
PaNern 
• Cause 
of 
a 
child’s 
intellectual 
disability 
can 
provide 
informaJon 
on: 
– Strengths 
and 
weaknesses 
– Can 
provide 
informaJon 
on 
what 
types 
of 
behaviour 
and 
emoJonal 
difficulJes 
child 
may 
present. 
25
Causes 
of 
ID 
& 
Behaviour 
PaNern 
Fragile 
X 
• DistracJble, 
impulsive, 
overacJve, 
short 
aNenJon 
span 
• Anxious, 
shy, 
poor 
eye 
contact 
• Anxiety 
may 
present 
as 
tantrums 
• Hand 
flapping, 
sound 
/ 
light 
sensiJviJes, 
sensiJvity 
to 
touch 
• Changes 
in 
rouJne 
-­‐ 
problemaJc 
• DifficulJes 
with 
crowds, 
new 
situaJons 
– 
can 
be 
overwhelming 
Down 
syndrome 
• Typically 
fewer 
emoJonal 
and 
behavioural 
problems 
compared 
to 
other 
children 
with 
ID 
– 
but 
sJll 
higher 
rates 
than 
typically 
developing 
children 
• InaNenJon, 
hyperacJvity 
• 
Stubborn 
• Depression 
26
Causes 
of 
ID 
& 
Behaviour 
PaNern 
AuJsm 
Spectrum 
Disorder 
• High 
levels 
of 
behaviour 
and 
emoJonal 
problems 
• DisrupJve 
behaviour 
– 
eg 
tantrums, 
aggression, 
abusive, 
noisy, 
impaJent, 
stubborn 
• Anxiety 
• DifficulJes 
with 
change 
in 
rouJne 
and 
surroundings 
• Symptoms 
of 
depression 
• InaNenJon, 
impulsivity, 
hyperacJvity 
• Social 
difficulJes 
Prader 
Willi 
syndrome 
• Hyperphagia 
-­‐ 
extreme 
unsaJsfied 
drive 
to 
consume 
food 
• Food 
foraging 
/ 
obsession 
with 
food 
• Increased 
appeJte, 
weight 
control 
issues 
• Temper 
tantrums, 
opposiJonal, 
argumentaJve 
• Stealing, 
lying, 
stubborn, 
rigid, 
possessive 
• Obsessive/compulsive 
behaviour 
• Skin 
picking 
• Impulsivity 
27
Causes 
of 
ID 
& 
Behaviour 
PaNern 
Williams 
syndrome 
• Friendly, 
outgoing, 
loquacious 
• Short 
aNenJon 
span 
and 
distracJbility 
• Difficulty 
modulaJng 
emoJons 
-­‐ 
extreme 
excitement 
when 
happy 
• Tearfulness 
in 
response 
to 
apparently 
mild 
distress 
• Terror 
in 
response 
to 
apparently 
mildly 
frightening 
events 
• Heightened 
sensiJvity 
to 
sounds 
(hyperacusis) 
• PerseveraJng 
on 
certain 
favourite 
conversaJonal 
topics 
• Anxiety, 
difficulJes 
with 
changes 
in 
rouJnes 
/ 
schedules 
• DifficulJes 
building 
friendships 
28
Thank 
you

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Management of behavioural crises

  • 1. Management of Behavioural Crisis in Children with Developmental Issues Dr. Norharlina Bahar Child & Adolescent Psychiatrist Hospital Selayang 29 August 2014
  • 2. Outline • What? • Causes • PrevenJon • Management: – Before – In the midst – ALer • Pharmacotherapy • Causes of ID and behavioural paNern 2
  • 3. What is behavioural crisis? • In full meltdown mode • The child is not capable of reasoning, being redirected, or learning replacement skills. • One off or frequently or ongoing? 3
  • 4. Challenging Behaviour in Children with Developmental Issues • 2 – 3 x more common (CorbeN, 1979; Richardson 1979; Eifeld, 1995; Tonge, 1998) • AgitaJon • Aggression • DisrupJve behaviour • Self-­‐injurous behaviour • A significant change in funcJon (loss of interests, withdrawal from family, etc.) • School expulsion and/or an inability to leave the home. 4
  • 5. PrevenJon • The most effecJve way to manage challenging behaviours is to try prevenJng them from happening rather than just focusing on what to do when or aLer the behaviour occurs. • Learn skills to help anJcipate and turn around an escalaJng situaJon. 5
  • 6. PosiJve Behaviour Support Approach • Consider the purpose or ‘why’ of the behaviour • Focus on prevenJng the behaviour from happening by avoiding or changing the circumstances that trigger the behaviour • Teach new behaviours or skills to replace the challenging behaviour 6
  • 7. What purpose (or FuncJon) does challenging behaviour serve? • All behaviour happens for a reason • Health problems -­‐ may cause challenging behaviour or make it worse. • Common reasons are: – Interact with someone – Social aNenJon: e.g. shouJng – To get something: A person may learn behaviours that get them things they want. – Escape or avoid a demand/ request/ situaJon/ object/ person – Sensory: to get/ avoid sensory sJmulaJon i.e. rocking, humming – Get some control or predictability over their day or the acJvity – Reduce their arousal and or anxiety. 7
  • 8. FuncJonal Assessment • To find out the exact causes of a person’s behaviour • Keep a record: 1. DescripJon of the behaviour i.e. exactly what happens 2. Early warning signs, e.g. becoming red in the face 3. What happens before the behaviour, e.g. does something trigger the behaviours? Noisy environment? Being told no? etc. 4. What happens aLer the event, i.e. what is the person gejng or not gejng from the behaviour that makes them do it again? 8
  • 9. Have a Crisis Plan • PreparaJon and strategies for coping and staying safe in these situaJons • To be developed by family & the treaJng team 9
  • 10. A well-­‐designed plan includes 1. Defined sejng events, triggers or signs that a crisis situaJon might develop 2. Tools and strategies for keeping the individual and those around him safe in any sejng (school, home, community) 3. IntervenJon steps and procedures promoJng de-­‐escalaJon that are paired at each level with increasing levels of agitaJon 4. Lists of things to do and NOT to do specific to the needs, history & fears of the individual 5. Hands on training and pracJce for caregivers 6. ConJnued re-­‐evaluaJon of the effecJveness of the plan 7. Knowledge of facility if hospitalizaJon needed 8. Maintain safety first and foremost. This is not the Jme to teach, make demands, or to shape behavior. 10
  • 11. Ways to Calm an EscalaJng SituaJon • Be on alert for triggers and warning signs. • Try to reduce stressors by removing distracJng elements, going to a less stressful place or providing a calming acJvity or object. • Remain calm, as his behavior is likely to trigger emoJons in you. • Be gentle and paJent. • Give him space. • Provide clear direcJons and use simple language. • Focus on returning to a calm state by allowing Jme in a quiet, relaxaJon-­‐promoJng acJvity. • Praise aNempts to self-­‐regulate and the use of strategies such as deep breathing. • Discuss the situaJon or teach alternate and more appropriate responses once calm has been achieved. 11
  • 12. In the midst of a Crisis SituaJon • Remain as calm as possible • Assess the severity of the situaJon • Follow the Crisis Plan and focus on safety • Determine whom to contact • Dial 999 for an emergency • Remember: this is not a ‘teachable’ moment. 12
  • 13. • Consider the safety of your child & those around them: – can you remove your child from the situaJon safely? – do you need to remove yourself and other family members from the room or situaJon? – do you need to remove items from the environment or room that could be unsafe? • Consider the language you use with your child to avoid escala7on: – avoid talking as much as possible (stressful to have to work out what your words mean) – Use short, simple instrucJons if needed (include a visual clue eg. Opening door to show your child they can go outside to calm) – use a calm even voice. 13
  • 14. • Try to regain calm as quickly as possible by: – What will help the child calm as quickly as possible (Jme alone, access to an acJvity or item he/she likes that is calming) – What will help you calm as quickly as possible (leaving the room, gejng other family members safe, gejng back-­‐up) – Allow lots of Jme for recovery 14
  • 15. Challenges for Medical Professionals • Listen to the caregiver and the paJent to the extent possible. They're very unique in how they interact. • Do not think that we know beNer. • Aim to least restricJve care. • Family: be prepared to advocate yourself 15
  • 16. Physical Restraints, Seclusion & Rapid TranquillizaJon • When behaviors pose a risk of physical harm to the individual or others, a brief intervenJon are someJmes necessary to maintain safety. • Physical restraints -­‐ immobilizing or reducing the ability of an individual to move their arms, legs, body freely. • Seclusion -­‐ pujng the individual briefly in a room by himself to ‘calm down’. 16
  • 17. Physical Restraints, Seclusion & Rapid TranquillizaJon (cont) • As last resort and when less restricJve methods are not effecJve or feasible. • Improper use can have serious consequences physically and emoJonally • Must take place within the legal framework ie. Consent or Mental Health Act 17
  • 18. Rapid TranquillizaJon • The aim is to achieve a state of calm sufficient to minimize the risk posed to the individual or to others. • Rapid tranquillisaJon with intramuscular or intravenous injecJons should only be used in healthcare sejngs with appropriate resuscitaJons need. 18
  • 19. Assessment • History • Previous hx of anJpsychoJc? Non-­‐drug approach • de-­‐escalaJon techniques, e.g. talking down, distracJon, Jme out • Inform paJent/ carer re medicaJon Oral • Lorazepam 0.5 -­‐ 2mg • Olanzapine Zydis 2.5 mg – 5mg • Risperidone 0.5 – 1mg IV/IM • (Lorazepam) • Midazolam 2.5 – 15 mg • Haloperidol 2.5 – 10 mg Monitoring & Nursing • Vital signs • Low sJmulus environment Repeat • Wait at least 30 minutes 19 Maudley Guideline, 2012, Byrne, 2012; Heyman 2003; NICE 2006
  • 20. De-­‐escalaJon • Maintain adequate distance. Respect personal space • Do not be provocaJve. • Ensure the environment is conducive for calmness. • Be calm & self-­‐assured, use non-­‐threatening, non-­‐verbal communicaJon. • Be concise, use repeJJon. • Explained intenJon, set clear limits. • Offer choices 20
  • 21. The Use of MedicaJon • Aimed at target symptoms eg. to achieve state of calm; paJent will hit others less frequently; psychoJc symptoms; irritability • Comprehensive assessment of the individual's emoJonal and behavioural disturbance and assessment of the efficacy of all previous modes of treatment. • Issue of informed consent & legal maNer • Should be integrated with other concurrent treatments. MedicaJon alone to is not sufficient. 21
  • 22. The Use of MedicaJon (cont) • SomeJmes unrealisJc demands to solve the problem by prescribing medicaJon. • Children with developmental issues are more vulnerable for side-­‐effects. 22
  • 23. Pharmacotherapy • Risperidone -­‐ effecJve and well tolerated for the treatment of agitaJon, aggression, or self-­‐ injurious behavior in children with ASD (McCracken 2002, Davies 2006) & ID (Unwin 2011, DeDyn 2006) • Aripiprazole is effecJve for irritability in children with ASD (Ching, 2012) • Off-­‐label use: QueJapine, Olanzapine, Paliperidone (Golubchik 2011, SJgler 2012, Hollander 2010) 23
  • 24. Pharmacotherapy (cont) • SSRI ie sertraline, fluvoxamine : comorbid depression, OCD, anxiety (Hellings 1996, Campbell 1995) • Benzodiazepines : short term, anxiety. Paradoxical effect (Barron, 1985) • Valproate : mood lability, irritability, aggression (Kastner 1990) • SJmulant : comorbid ADHD (Arnold 1998, Handen 1999) 24
  • 25. Causes of ID & Behaviour PaNern • Cause of a child’s intellectual disability can provide informaJon on: – Strengths and weaknesses – Can provide informaJon on what types of behaviour and emoJonal difficulJes child may present. 25
  • 26. Causes of ID & Behaviour PaNern Fragile X • DistracJble, impulsive, overacJve, short aNenJon span • Anxious, shy, poor eye contact • Anxiety may present as tantrums • Hand flapping, sound / light sensiJviJes, sensiJvity to touch • Changes in rouJne -­‐ problemaJc • DifficulJes with crowds, new situaJons – can be overwhelming Down syndrome • Typically fewer emoJonal and behavioural problems compared to other children with ID – but sJll higher rates than typically developing children • InaNenJon, hyperacJvity • Stubborn • Depression 26
  • 27. Causes of ID & Behaviour PaNern AuJsm Spectrum Disorder • High levels of behaviour and emoJonal problems • DisrupJve behaviour – eg tantrums, aggression, abusive, noisy, impaJent, stubborn • Anxiety • DifficulJes with change in rouJne and surroundings • Symptoms of depression • InaNenJon, impulsivity, hyperacJvity • Social difficulJes Prader Willi syndrome • Hyperphagia -­‐ extreme unsaJsfied drive to consume food • Food foraging / obsession with food • Increased appeJte, weight control issues • Temper tantrums, opposiJonal, argumentaJve • Stealing, lying, stubborn, rigid, possessive • Obsessive/compulsive behaviour • Skin picking • Impulsivity 27
  • 28. Causes of ID & Behaviour PaNern Williams syndrome • Friendly, outgoing, loquacious • Short aNenJon span and distracJbility • Difficulty modulaJng emoJons -­‐ extreme excitement when happy • Tearfulness in response to apparently mild distress • Terror in response to apparently mildly frightening events • Heightened sensiJvity to sounds (hyperacusis) • PerseveraJng on certain favourite conversaJonal topics • Anxiety, difficulJes with changes in rouJnes / schedules • DifficulJes building friendships 28