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MAMMOGRAPHY
DR. HADEYA ANJUM (PT)
1
What is a Mammogram
• A mammogram is an x-ray exam of
the breast to detect and evaluate any
change in the breast
2
History
 X-rays were first used to examine breast tissue by the
German surgeon ALBERT SALOMON about a century ago
• Modern mammography came in to existence since the late
1960s
• Technology has advanced and today’s machine is different
even from those of 1980s and 1990s
3
Mammography machine
• Today’s mammography machine expose the breast to much
less radiation
• X-rays do not go through tissue as easily as those used for
routine chest x-ray or x-rays of extremity
4
Radiation from mammogram
• Modern machine is safe and uses the lowest dose of radiation
possible.
• If a woman with breast cancer is treated with radiation, she will get
several thousand rads.
• If she has yearly mammogram starting at age of 40 and continues
until 90 she will get total of 20-40 rads.
• Benefits of mammography outweigh any possible harm from the
radiation exposure
5
Types of mammogram
• Screening mammogram
• Diagnostic mammogram
6
Screening mammogram
• Mammogram of the breast for the women who have no sign
or symptom of breast cancer, usually with two x-ray views
• Finding breast cancer early, greatly improves a woman’s
chance for successful treatment
7
Diagnostic mammogram
• X-ray of the breast for a woman with breast problem like lump
or nipple discharge or an abnormal area found in screening
by taking spot view or magnification view
8
What diagnostic mammogram does ?
• It may reveal that an area that looked abnormal on screening
is actually NORMAL—routine checkup
• It could reveal that an area of abnormal tissue probably is
NOT CANCER but radiologist may not ready to say it normal
based on these x-rays--- re-check up in 4-6 months
• The results could also suggest that a biopsy is needed to find
out if the abnormal area is CANCER
9
Types of mammogram machine
• Screen - film units
• Full - field digital mammography units (better in woman
younger than 50 or with dense breast tissue)
10
How is mammogram done
Breast is briefly compressed between
2 plates attached to the mammogram
machine–
an adjustable plastic plate on top and
a fixed plate on bottom which holds
the x-ray film or the digital detector
that makes the image
11
Typical views
• For screening:
Cranio- caudal view (CC)
Medio-lateral oblique(MLO)
• For diagnostic:
CC MLO – lateromedial (from side towards center of chest) –
mediolateral (from the center of the chest out) - Spot compression
view
12
Craniocaudal view
13
14
Mediolateral oblique view
15
16
How to read mammogram
• Its challenging must be interpreted by radiologist
• Must to compare with previous mammogram
17
Changes in breast tissue
• Calcification:
macrocalcification & microcalcification
• Mass
• Breast density
18
Calcification (macro)
• Due to changes in breast caused by aging of breast arteries,
old injuries or inflammation
• Coarse/ large Calcium deposit
• Seen in 1 0f 10 women under 50 and about half over 50
• These deposits are related to Noncancerous condition and do
not require biopsy
19
Calcification (micro)
• Tiny specks of calcium
• If seen it’s a matter of concern though not necessarily it is
cancer or does not mean biopsy
20
Mass
• Mass with or without calcification
• Noncancerous mass:
Cystic – fluid filled sacs/ simple cyst
Solid – Fibro adenoma
• Complex or mixed mass: suspect cancer needs Fine Needle
Aspiration Cytology or biopsy Breast ultrasound is complementary
21
Breast density
Density is based on:
• how much fibrous and glandular tissue
• how is the distribution within breast tissue
• how is breast made up of fatty tissue
• Dense breasts are not abnormal but they are linked to higher
risk of breast cancer
22
Findings on mammogram
• Primary signs of breast cancer may include spiculated
masses or clustered pleomorphic microcalcification
• Secondary signs of breast cancer may include asymmetrical
tissue density, skin thickening or retraction or focal distortion
of tissue
23
24
Impression
• Overall assessment of the radiological findings often includes
a classification of the mammogram using the BI-RADS
system developed by the American College Of
Radiology(ACR)
25
Normal mammogram
26
Mass on mammogram
27
Recommendation
• No action necessary
• A six month follow up mammogram
• Spot views
• Breast ultrasound
• Biopsy etc
28
Limitations of mammography
• Breast cancer screening is the best way to find cancer early
but finding cancer early does not always reduce a woman’s
chance of dying from breast cancer
• Detecting breast cancer early may not help prolong the life of
a woman who has other kind of serious or life threatening
health problem like CCF, ESRD, COPD…
29
False negative results
• A false-negative mammogram appears normal even though
with breast cancer
• It occurs more often among younger women usually had
dense breast
• False-negative results can delay treatment and promote a
false sense of security for the woman Overall, screening
mammogram miss about 1 in 5 breast cancers
30
False positive results
• A false- positive mammogram looks abnormal but no cancer
is actually present
• It requires diagnostic mammogram, ultrasound, MRI or even
biopsy
• It is common in younger woman, have dense breast, have
had breast biopsy or cancer in family or are taking estrogen
31
Tomosynthesis
• Newer technique
• Basically it is an extension of digital mammogram
• Breast is compressed once, machine takes many low dose x-
rays as it moves over the breast in an arc, images can then be
combined into a 3-dimensional picture
32
33
Mammogram report
• Patient information
• Clinical history
• Procedure: Screening or Diagnostic
• Findings: mass, calcification, asymmetry architectural distortion or
associated lesion
• Comparison to previous study/Any U/S
• Impression/ Final assessment
• Management Recommendation
34
Expert quote
“Before you go to get a mammogram, make sure you know whether you're there
for a screening mammogram or a diagnostic mammogram. If you're there for
your annual screening mammogram, you may not meet with the radiologist or
get your results the same day. Sometimes, there's an advantage to this. Getting
your results later often means having two doctors look at your mammogram. A
lump, pain, nipple discharge, breast implants, or breast surgery automatically
make your mammogram diagnostic. If you have a lump, or other symptoms, tell
the mammography center so they know what they're dealing with.”
-- Susan Greenstein Orel, M.D
35
Male mammography
• 1300 men get breast cancer per year – 1/3 die
• Most are 60 years or older
• Nearly all are primary tumors
Symptoms include:
– Nipple retraction
– Crusting
– Discharge
– Ulceration 36
37
Gynecomastia
• It is a benign male breast (non-cancerous) condition
• Some men who have prominent breasts, or uneven breasts,
often feel some embarrassment about their body image.
• This condition can also cause emotional conflict over sexual
identity.
38
39
40

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Mammography

  • 2. What is a Mammogram • A mammogram is an x-ray exam of the breast to detect and evaluate any change in the breast 2
  • 3. History  X-rays were first used to examine breast tissue by the German surgeon ALBERT SALOMON about a century ago • Modern mammography came in to existence since the late 1960s • Technology has advanced and today’s machine is different even from those of 1980s and 1990s 3
  • 4. Mammography machine • Today’s mammography machine expose the breast to much less radiation • X-rays do not go through tissue as easily as those used for routine chest x-ray or x-rays of extremity 4
  • 5. Radiation from mammogram • Modern machine is safe and uses the lowest dose of radiation possible. • If a woman with breast cancer is treated with radiation, she will get several thousand rads. • If she has yearly mammogram starting at age of 40 and continues until 90 she will get total of 20-40 rads. • Benefits of mammography outweigh any possible harm from the radiation exposure 5
  • 6. Types of mammogram • Screening mammogram • Diagnostic mammogram 6
  • 7. Screening mammogram • Mammogram of the breast for the women who have no sign or symptom of breast cancer, usually with two x-ray views • Finding breast cancer early, greatly improves a woman’s chance for successful treatment 7
  • 8. Diagnostic mammogram • X-ray of the breast for a woman with breast problem like lump or nipple discharge or an abnormal area found in screening by taking spot view or magnification view 8
  • 9. What diagnostic mammogram does ? • It may reveal that an area that looked abnormal on screening is actually NORMAL—routine checkup • It could reveal that an area of abnormal tissue probably is NOT CANCER but radiologist may not ready to say it normal based on these x-rays--- re-check up in 4-6 months • The results could also suggest that a biopsy is needed to find out if the abnormal area is CANCER 9
  • 10. Types of mammogram machine • Screen - film units • Full - field digital mammography units (better in woman younger than 50 or with dense breast tissue) 10
  • 11. How is mammogram done Breast is briefly compressed between 2 plates attached to the mammogram machine– an adjustable plastic plate on top and a fixed plate on bottom which holds the x-ray film or the digital detector that makes the image 11
  • 12. Typical views • For screening: Cranio- caudal view (CC) Medio-lateral oblique(MLO) • For diagnostic: CC MLO – lateromedial (from side towards center of chest) – mediolateral (from the center of the chest out) - Spot compression view 12
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  • 17. How to read mammogram • Its challenging must be interpreted by radiologist • Must to compare with previous mammogram 17
  • 18. Changes in breast tissue • Calcification: macrocalcification & microcalcification • Mass • Breast density 18
  • 19. Calcification (macro) • Due to changes in breast caused by aging of breast arteries, old injuries or inflammation • Coarse/ large Calcium deposit • Seen in 1 0f 10 women under 50 and about half over 50 • These deposits are related to Noncancerous condition and do not require biopsy 19
  • 20. Calcification (micro) • Tiny specks of calcium • If seen it’s a matter of concern though not necessarily it is cancer or does not mean biopsy 20
  • 21. Mass • Mass with or without calcification • Noncancerous mass: Cystic – fluid filled sacs/ simple cyst Solid – Fibro adenoma • Complex or mixed mass: suspect cancer needs Fine Needle Aspiration Cytology or biopsy Breast ultrasound is complementary 21
  • 22. Breast density Density is based on: • how much fibrous and glandular tissue • how is the distribution within breast tissue • how is breast made up of fatty tissue • Dense breasts are not abnormal but they are linked to higher risk of breast cancer 22
  • 23. Findings on mammogram • Primary signs of breast cancer may include spiculated masses or clustered pleomorphic microcalcification • Secondary signs of breast cancer may include asymmetrical tissue density, skin thickening or retraction or focal distortion of tissue 23
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  • 25. Impression • Overall assessment of the radiological findings often includes a classification of the mammogram using the BI-RADS system developed by the American College Of Radiology(ACR) 25
  • 28. Recommendation • No action necessary • A six month follow up mammogram • Spot views • Breast ultrasound • Biopsy etc 28
  • 29. Limitations of mammography • Breast cancer screening is the best way to find cancer early but finding cancer early does not always reduce a woman’s chance of dying from breast cancer • Detecting breast cancer early may not help prolong the life of a woman who has other kind of serious or life threatening health problem like CCF, ESRD, COPD… 29
  • 30. False negative results • A false-negative mammogram appears normal even though with breast cancer • It occurs more often among younger women usually had dense breast • False-negative results can delay treatment and promote a false sense of security for the woman Overall, screening mammogram miss about 1 in 5 breast cancers 30
  • 31. False positive results • A false- positive mammogram looks abnormal but no cancer is actually present • It requires diagnostic mammogram, ultrasound, MRI or even biopsy • It is common in younger woman, have dense breast, have had breast biopsy or cancer in family or are taking estrogen 31
  • 32. Tomosynthesis • Newer technique • Basically it is an extension of digital mammogram • Breast is compressed once, machine takes many low dose x- rays as it moves over the breast in an arc, images can then be combined into a 3-dimensional picture 32
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  • 34. Mammogram report • Patient information • Clinical history • Procedure: Screening or Diagnostic • Findings: mass, calcification, asymmetry architectural distortion or associated lesion • Comparison to previous study/Any U/S • Impression/ Final assessment • Management Recommendation 34
  • 35. Expert quote “Before you go to get a mammogram, make sure you know whether you're there for a screening mammogram or a diagnostic mammogram. If you're there for your annual screening mammogram, you may not meet with the radiologist or get your results the same day. Sometimes, there's an advantage to this. Getting your results later often means having two doctors look at your mammogram. A lump, pain, nipple discharge, breast implants, or breast surgery automatically make your mammogram diagnostic. If you have a lump, or other symptoms, tell the mammography center so they know what they're dealing with.” -- Susan Greenstein Orel, M.D 35
  • 36. Male mammography • 1300 men get breast cancer per year – 1/3 die • Most are 60 years or older • Nearly all are primary tumors Symptoms include: – Nipple retraction – Crusting – Discharge – Ulceration 36
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  • 38. Gynecomastia • It is a benign male breast (non-cancerous) condition • Some men who have prominent breasts, or uneven breasts, often feel some embarrassment about their body image. • This condition can also cause emotional conflict over sexual identity. 38
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