Malaria is a serious infectious disease transmitted through mosquito bites. It causes fever, chills, and can be fatal, especially in children. The parasite has complex life cycles in both humans and mosquitoes. In humans, it infects liver cells and red blood cells. Diagnosis is typically made by examining blood smears under a microscope to identify the parasite. Prevention involves reducing mosquito exposure and taking antimalarial medications when traveling to affected regions.
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. It is preventable and curable.
Malaria is a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. It is preventable and curable.
Drug resistance against malaria
Seminar Prepared by:
Mohammed Musa
Mohammed Saadi
Ali Abdulazeem
Nora Shaker
Shilan Adnan
Parasitology
College of Medicine - University of Kirkuk
Drug resistance against malaria
Seminar Prepared by:
Mohammed Musa
Mohammed Saadi
Ali Abdulazeem
Nora Shaker
Shilan Adnan
Parasitology
College of Medicine - University of Kirkuk
Protozoan parasites characterized by the production of spore-like oocysts containing sporozoites were known as sporozoa.
They live intracellularly, at least during part of their life cycle
"Unveiling Malaria: Understanding, Prevention, and Treatment"MMariSelvam4
"Malaria: A Persistent Global Health Challenge"
Malaria, a mosquito-borne disease caused by the Plasmodium parasite, continues to be a major public health concern worldwide. This presentation sheds light on the multifaceted nature of malaria, addressing its prevalence, transmission, impact on global health, and ongoing efforts towards prevention and treatment.
Despite significant progress in recent years, malaria remains prevalent in many parts of the world, especially in sub-Saharan Africa, where it disproportionately affects vulnerable populations such as children and pregnant women. The disease is transmitted through the bite of infected Anopheles mosquitoes, making vector control a crucial aspect of malaria prevention.
Efforts to combat malaria encompass a range of strategies, including the distribution of insecticide-treated bed nets, indoor residual spraying, and the development of effective antimalarial drugs. Additionally, ongoing research focuses on innovative approaches such as genetic modification of mosquitoes and the development of vaccines to further advance malaria control efforts.
The burden of malaria extends beyond its immediate health impact, affecting socioeconomic development in endemic regions and exacerbating health disparities. Achieving malaria eradication requires a concerted effort involving governments, international organizations, healthcare providers, researchers, and communities.
By raising awareness, advocating for increased funding and resources, and implementing evidence-based interventions, we can work towards the ultimate goal of eradicating malaria and ensuring health equity for all. Together, we can make significant strides in reducing the global burden of this preventable and treatable disease.
Muktapishti is a traditional Ayurvedic preparation made from Shoditha Mukta (Purified Pearl), is believed to help regulate thyroid function and reduce symptoms of hyperthyroidism due to its cooling and balancing properties. Clinical evidence on its efficacy remains limited, necessitating further research to validate its therapeutic benefits.
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Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
2. KNOW MALARIA AND WHY
Malaria is an acute and chronic illness characterized by
paroxysms of fever, chills, sweats, fatigue, anemia, and
splenomegaly.
Malaria is of overwhelming importance in the developing
world today, with an estimated 300 to 500 million cases and
more than 1 million deaths each year.
Most malarial deaths occur among infants and young
children.
3. MODES OF MALARIA TRANSMISSION
Bite of female anopheline mosquitoes: Infective form:
sporozoites
Infection of blood of a malaria patient containing asexual
forms- ‘trophozoite’ induced malaria
1. Trasfusion malaria
2. Congenital malraia
3. Malaria in drug addicts
4. HOSTS INVOLVED IN TRANSMISSION OF MALARIA
Man Female anopheles mosquito
Secondary host Primary host
Intermediate host Definitive host
Asexual cycle Sexual cycle
Schizogony Sporogony
5.
6. HUMAN CYCLE OF PLASMODIUM
1. Pre erythrocytic schizogony
Development of sporozoites in liver parenchyma
Liberated merozoites are called as cryptozoites
Blood is sterile
2. Erythorcytic schizogony
Parasite resides inside RBCs; passes through stages of
Trophozoite, Shcizont, Merozoite
Parasitic multiplication brings clinical attack of malaria
7. 3. Gametogony
Some merozoites develop in RBCs of spleen and bone
marrow to form ‘Gametocytes’
4. Exo erythorocytic schizogony
Persistence of late tissue phase in liver
Seen in P vivax and P ovale
Cause relapses in Vivax and Ovale malaria
Liberated merozoites are known as ‘Phanerozoites’
8. MOSQUITO CYCLE OF PLASMODIUM
1. Completion of gametogomy
Exflagellation of microgamete and maturation of gametes
Fusion of gametes form Zygote; Zygote matures to Ookinite
2. Sporogony
Ookinite develops into oocyst
On 10th day of infection, oocyst ruptures, relasing
sporozoites; sporozoites reach salivary glands
Mosquito at this stage is capable of transmitting infection.
9. Once inside the erythrocyte, the parasite transforms
into the ring form, which then enlarges to become a
trophozoite.
These latter 2 forms can be identified with Giemsa
stain on blood smear, the primary means of
confirming the diagnosis of malaria
10.
11. Paroxysms coincide with the rupture of schizonts that occurs
every 48 hr with P. vivax and P. ovale, resulting in fever spikes
every other day- tertian malaria
every 72 hr with P. malariae, resulting in fever spikes every 3rd
or 4th day- quartan marlaria
Periodicity is less apparent with
P. falciparum and mixed infections
travelers from nonendemic regions
13. DIAGNOSIS
The diagnosis of malaria
Giemsa-stained smears of peripheral blood or
rapid immunochromatographic assay.
Stains used for diagnosis
Giemsa stain >Wright stain or Leishman stain.
Thick and Thin blood smears
The concentration of erythrocytes on a thick smear is 20-40 times
that on a thin smear and is used to quickly scan large numbers of
erythrocytes.
The thin smear allows for positive identification of the malaria
species and determination of the percentage of infected
erythrocytes and is useful in following the response to therapy
14. DIAGNOSIS
A single negative blood smear does not exclude
malaria.
Most symptomatic patients with malaria will have
detectable parasites on thick blood smears within
48 hr.
16. PREVENTION
Malaria prevention consists of
Reducing exposure to infected mosquitoes and
Chemoprophylaxis
Chemoprophylaxis is necessary for
all visitors to and
residents of the tropics who have not lived there since
infancy, including children of all ages.
Health care providers should consult the latest information
on resistance patterns before prescribing prophylaxis for their
patients.