The document discusses methods for closing spaces during orthodontic treatment. It describes two main methods: sliding mechanics and loop mechanics. Sliding mechanics involve sliding brackets along the archwire using elastics or coils, while loop mechanics use loops of wire between brackets to close spaces without bracket movement. The document outlines considerations for each method and discusses techniques for closing extraction spaces and retracting canines specifically. It also notes potential problems and solutions during space closure.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Frictionless Mechanics in Orthodontics
In frictionless mechanics, teeth are moved without the brackets sliding
over the archwire.
Retraction is accomplished with the help of loops or springs.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Anchorage in beggs technique /certified fixed orthodontic courses by Indian d...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Frictionless Mechanics in Orthodontics
In frictionless mechanics, teeth are moved without the brackets sliding
over the archwire.
Retraction is accomplished with the help of loops or springs.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Anchorage in beggs technique /certified fixed orthodontic courses by Indian d...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Friction less mechanics in orthodontics /certified fixed orthodontic course...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Arch forms 1 /orthodontics course training by Indian Dental Academy /certifie...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
Alignment and Leveling of teeth is usually the fundamental and the most important objective of orthodontics during initial phase of fixed orthodontic treatment.
Retraction mechanics in swa 2 /certified fixed orthodontic courses by Indian ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Bioprogressive therapy /certified fixed orthodontic courses by Indian dental ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Friction less mechanics in orthodontics /certified fixed orthodontic course...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Arch forms 1 /orthodontics course training by Indian Dental Academy /certifie...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy has a unique training program & curriculum that provides students with exceptional clinical skills and enabling them to return to their office with high level confidence and start treating patients
State of the art comprehensive training-Faculty of world wide repute &Very affordable.
Alignment and Leveling of teeth is usually the fundamental and the most important objective of orthodontics during initial phase of fixed orthodontic treatment.
Retraction mechanics in swa 2 /certified fixed orthodontic courses by Indian ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Bioprogressive therapy /certified fixed orthodontic courses by Indian dental ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Space closure by frictionless mechanics 2 /certified fixed orthodontic course...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Space closure /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Space closure 2 /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
biomechanics of space closure in orthodonticcs / fixed orthodontics coursesIndian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Space closure 1 /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Elastics & elastomerics /certified fixed orthodontic courses by Indian dental...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Elastics and elastomerics /certified fixed orthodontic courses by Indian dent...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Nickel titanium in orthodontics /certified fixed orthodontic courses by India...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Space closure /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Begg light-wire appliance remains unique in the history of orthodontic innovation. Whereas many current self-ligating bracket appliances purport to be low friction or friction free, it is the Begg appliance that best exemplifies low friction, free sliding mechanics.
By creating only a single point of contact between the bracket and the arch-wire Dr Begg was able to greatly decrease resistance to sliding, both by reducing friction between the bracket and the arch-wire and virtually eliminating the binding of the arch-wire in the bracket slot, as is seen in all horizontal slot brackets.
Begg’s bracket design allowed teeth to freely tip mesially and distally as well as lingually and labially. This often gave teeth the appearance of being over tipped during treatment and required considerable diligence by Begg practitioners to keep tooth movement under control.
This freedom of tooth movement allowed unprecedented correction of large overbites and overjets to an edge-to-edge position and rapid closure of extraction spaces by initially tipping the adjacent teeth into the extraction site and uprighting the teeth afterwards.
Individual tooth root correction was managed by the use of fine springs that were designed, and often individually crafted to upright, torque and rotate teeth into their correct positions once the position of tooth crowns had been established.
One key advantage of the appliance set up was the use of light elastic forces for the correction of anterior overbites and overjets. All anchorage could be established intra-orally without headgear, without the need for ancillary appliances such as trans-palatal arches, or needing to set up molar anchorage prior to treatment, as Dr Tweed advocated.
Loops in orthodontics /certified fixed orthodontic courses by Indian dental ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Do you know what is a cerclage cable? During hip replacement and treatment of associated peri-prosthetic fractures, it is often necessary to hold the bone or fragments of bone together to create a stable environment for healing to occur. This is typically done with metal wires or cables using a technique called Cerclage. A cerclage wire or cable is wound around a bone or bony fragments to hold them together to allow them to heal.
Orthodontic wires are used to carry out the necessary tooth movements as part of orthodontic treatment. A variety of materials are used to produce orthodontic wires. The archwire has been an integral part of the orthodontic appliance, and the high esthetic demand by the patient, along with the introduction of composite and ceramic brackets initiated research for esthetic archwires to go with these brackets. Esthetic archwires available are composite, optiflex and coated archwires. Appropriate use of all the available wire types may enhance patient comfort and reduce chairside time as well as the duration of treatment. The individual clinician must always know and understand the needs and options at every stage of therapy
The art of orthodontics involves correction of the position of teeth and the relation of craniofacial structures.
The Teeth are moved by the use of forces and moments, which are delivered through the use of various types of wires.
From the beginning of the profession, different types of wires have been introduced to provide forces to move teeth.
Light and Continuous Forces have always been sought, and operators have tried to achieve this in a variety of ways.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Canine retraction /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
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Protonitazene (hydrochloride) CAS: 119276-01-6
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Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
2. Outlines
1) Introduction.
2) Methods of space closure:
Sliding mechanics.
Loop mechanics.
3) Closure of extraction spaces:
Moderate anchorage treatment with 18 & 22-slot
edgewise.
Maximum anchorage treatment with 18 & 22-slot
edgewise.
Minimum anchorage treatment.
4) Retraction methods.
5) References.
3. Introduction
Space closure is an important step on
orthodontic mechanotherapy ,solely dictated
by clinical treatment objectives and
irrespective of method employed.
Space closure should be individually tailored
based on the diagnosis and treatment plan.
Selection of any method should be based on
desired tooth movement.
4. Goals for any space closure method
• Differential space closure capability.
• Axial inclination control.
• Control of rotation and arch width.
• Optimum biological response.
• Minimum patient cooperation.
• Operator convenience.
5. closureDeterminants of space
• Amount of crowding.
• Anchorage .
• Axial inclination of canine and incisors.
• Midline discrepancy and R/L symmetry.
• Vertical dimensions.
6. When you start space closure??
After alignment and leveling when you reach the
working arch wire.
18-slot 16x22 SS.
22-slot 19x25 SS.
7. Methods of space closure
Sliding mechanics (frictional system):
The bracket slides along the arch wire by using
elastics, Niti coil spring or others.
Loop mechanics (frictionless system):
The teeth are moved without the bracket sliding
along the arch wire by a numerous design of
springs and loops.
8. Sliding mechanics
• Teeth slide along the arch wire by energy stored in elastic
or wire coil spring.
• Usual use 19x25 SS arch wire and place coil spring from a
hook on the arch wire to the hook on molar band.
• Pre-adjusted appliances facilitate sliding mechanics
because the level-slot line-up means that torque can stay
passive during sliding.
9. Sliding mechanics
Advantages:
• Minimal wire bending time.
• Initial wire placement is less time consuming.
• Enhances patient comfort.
• More efficient sliding of arch wire through posterior bracket slots.
Disadvantages:
• Confusion concerning the ideal force levels.
• Tendency to over activate the elastic and spring forced which cause
initial tipping and need time for tooth uprightening.
• Variable forces.
• Degradation of force.
• Slower than loop mechanics due to friction.
• Staining of E-chain.
10. Types of sliding mechanics:
1) Movement of brackets along an arch wire.
2) Movement of arch wire through brackets.
Methods of canine retraction in sliding mechanics:
Elastic module with ligature.
Elastomeric chains.
Coil springs.
11. Elastic modules with ligature
• A single elastic module used to secure arch wire
to brackets is attached to canine by ligature wires
extending from the molar.
• These tiebacks are activated 2-3 mm or twice
their original size to produce 100-150 gm of force.
Elastomeric Chain
• Introduced to orthodontic at 1960.
• Used for canine retraction,diastema closure,
rotation correction, arch constriction.
12. Advantages:
• Inexpensive.
• Relatively hygienic.
• Easily applied.
• No need for patient cooperation.
Disadvantages:
• Decreased and loss of effectiveness.
• Chance of breakage.
• Staining.
• Difficult to clean.
13. Clinical consideration when using elastic
• To optimize tooth movement, sufficient time should
be allowed for distal root movement to occur.
• A common mistake is to change the elastic chain or
module too often that lead to high force level and
M/F which cause distal crown tipping only.
• Also cause excessive mesial out rotation of canines.
• Excessive force can inhibit direct resorption around
the canine, bone resorption in posterior segment
with loss of anchorage.
• Elastic modules or chain should be changed every4-6
weeks.
14. Closed coil springs
• Introduced to orthodontic world at 1931.
Types :
1. S.S coil spring:
• Efficient for canine retraction.
• It has a higher load deflection rate compared to
Niti springs.
2. Niti coil spring.
3. Elgiloy coil spring.
15. • Samuels et al (1993), compared the space closing
effectiveness of elastic modules and “150gm” Niti
coil spring on 19x25 arch wire and found:
1. Niti springs produce more rapid and consistent
movement.
2. Elastic modules produce approx. 33% less
movement per unit time.
• 150gm coil spring is recommended.
(Samuels et al 1998)
16. • Niti coil spring (9mm) coils, (3mm of actual coil
spring) should not stretched by more than 9mm.
(Seidenbusch et al 1996)
• Force degradation in Niti spring ranged from
8 -17% over 28 days. (Angolkar et al 1992)
• Force degradation in elastomeric chain ranged
from 50-70% in the 1st day and 30-40% for the
remaining 3weeks. (Baty 1994)
17. Causes of failure of spaces to close with
sliding mechanics
1. Excessive friction: (1st suspected cause)
Situations in which friction excessive:
• Active forces between bracket & wire
(especially torque force)
• The ends of arch wire inside the molar tube.
• Bracket or tube may be distorted with distal-end cutter.
• Ceramic bracket produce more friction. (Kusy et al 1990)
• Excessive space closing force plus severe curve of spee cause
bowing of the wire.
• Multiple bracket distal to the space to be closed.
• Conventional ligation with elastomeric modules as figure of 8.
18. 2. Occlusal interference:
• Lower canine brackets can impede upper canine tip
when correcting Cl II relationship.
• Ricketts type utility & T-loop arches.
• Higher occlusal forces in adult & Cl II /2 cases.
3. Intra alveolar causes: (rare)
• Retained deciduous teeth fragments.
• Apices of extracted permanent teeth.
• Root too close:
Especially in the upper arch where canine
angulation is greater.
• Waisting of the bone:
Atrophy of the alveolus due to old tooth loss.
4. Idiopathic.
19. Sequence for dealing with a failure of
space closure with sliding mechanics
• Check for causes as listed previously.
• If no cause can be found and wire hard to swivel,
so the friction is too high.
• Steps to lower friction:
o Use thinner wire.
o Remove curve of spee with overbite situations.
o “ O ” configuration in one tie-wing only.
20. • Propping the bite with GIC on lower molars.
• Increase the force for one visit.
• Leaving the 2nd molar out of space closure for
1 or 2 visits.
• If the space still not closed, increase in force is
not advisable. Check again for friction &
occlusal interference, and consider switching
to closing loop mechanics.
21. Other methods for reduction of friction
• Wonder wire:
It is a dual diameter wire has a rectangular
anterior segment to maintain torque control &
round in cross section in posterior segment.
22. • Self - ligating brackets:
Use the elastic chain under the arch wire.
• Sectional mechanics:
Using TMA cantilever spring in the buccal
sulcus.
23. Problems during sliding mechanic of
canine retraction
Occlusal interference -solution: bite plane.
Poor canine control-solution: using a heavier
arch wire.
Rotation of canine mesiobuccally and molars
mesiopalatally-solution:palatal traction using
lingual cleats or buttons.
24. Loop mechanics
Advantages:
• No friction except for the bracket between the loop
and the space.
Disadvantages:
• fabrication; loop must not impinge on mucosa and
placed accurately between bracket.
• Need good oral hygiene.
• Increase flexibility at a stage when rigid wire is
needed.
• Small single loops give a short range of action.
• Difficult activation.
25. Closing loops
Design considerations:
• Fabricated from rectangular wire to prevent
rolling of wire in the bracket slot.
• The performance of the loop is determined by:
1.Spring properties:
Determined by wire material (SS, beta -Ti), size of
wire, distance between points of attachment.
26. 2.Moment:
It generates to bring the root apices together.
o Placing some of the wire of the loop in a horizontal
direction improves it is ability to deliver the
moments needed to prevent tipping.
o Additional moments must be generated by Gabel
bends.
27. 3. Location: there are 3 location
o Equal distance.
o Closure to anterior .
o Closure to posterior.
• If it is in the center of the span, it produce equal
force and equal couples on the adjacent teeth.
• If it is in one 1/3 of the distance between adjacent
brackets, the tooth closer to the loop extruded
with moment and the tooth far away intruded .
28.
29. 4. Fail safe:
Tooth movement should stop if patient not come
for scheduled appointment.
5. Design:
Should be simple, and loop more effective when
closed rather than opened.
30. Biomechanics of closing loops
Bends are placed on the mesial & distal legs of
loop, called Alpha& Beta bends.
These bends produce Alpha and Beta moments
when wire is placed into bracket.
Moment is determined by loop design.
Force is produced by loop activation.
Neutral Activated
31. If Beta moment > Alpha moment
Anchorage enhanced by mesial root movement of
posterior teeth with posterior extrusion& anterior
intrusion.
If Alpha moment > Beta moment
Anchorage of anterior segment increased by distal root
movement.
Anterior extrusion & posterior intrusion.
If both equal no vertical force.
32. Activation of loop:
• Pulling the distal end of wire through molar tube
and cinching back.
• Soldering a tie back mesial to molar tube on
arch wire.
33. • Moment to force ratio (M/F) determined the
type of tooth movement.
• Moment to force ratio for various tooth
movement:
( M/F Ratio) ( Tooth movement)
5 : 1 Uncontrolled tipping.
8 : 1 Controlled tipping.
10 : 1 Translation.
> 10: 1 Root movement.
34. M/F could be increased by: (Brustone& Koenig)
• Increase vertical dimension of loop.
• Increase horizontal dimension in the apical part of
loop.
• Increase the apical length of the wire.
• Helix incorporation.
• Angulation of loop legs.
• Decrease interbracket distance.
• Position of loop close to tooth to be retracted
bodily.
35. • The most way to increase M/F ratio by placing
Preactivation bends or Gable bends
(20 degree in each side).
36. Vertical loops
• There are 2 types:
1. Open vertical loop.
loop legs should be separated.
2. Close vertical loop.
loop legs should be closed together and parallel.
• Modified vertical loop like Omega loop.
38. Disadvantages of vertical loop:
• Very high force.
• Force & M/F extremely sensitive to small changes
in activation.
• Discomfort to the patient.
• Loss of anchorage and root control.
• Dumping of teeth.
• Small activation leads to rapid force decay &
intermittent force delivery.
39. Horizontal loops
1) Opus closing loop:
• Designed by Siatkowaski.
• Fabricated from 16x22 or 18x25 SS
or 17x25 TMA .
• Close space under good control.
• Activated by tightening it distally behind the molar
tube to produce maximal, moderate or minimal
incisor retraction.
40. 2) T-loop:
• Segmented T-loop made from 17x25 TMA.
• Continuous arch wire with T-loop:
Made from 16x22 SS or 19x25 SS.
41. Space closure problems during using
continuous arch wire T-loop
Tipping of anterior &posterior segments to the
extraction site-solution: increase alpha &beta
moment.
Flaring of anterior teeth-solution: reduce alpha
moments or increase distal activation.
Excessive lingual tipping of anterior teeth-
solution: increase alpha moment.
42. 3)Composite retraction spring:
• Designed by Brustone.
• Used with segmented arch technique for en
masse retraction of incisors or canine retraction.
• Made of 18mil beta-Ti wire(the loop) welded to
17x25 beta-Ti.
43. Closure of extraction spaces
• To obtain the desired result of closing spaces
within the arch, it is essential to control the
amount of incisor retraction versus molar and
premolar protraction.
• It depends on the amount anchorage needed.
44. • Most patients fall into the moderate anchorage
category, it is desired to close the reminder of
premolar extraction space with 50:50 or 60:40
ratio of anterior retraction to posterior
protraction.
• The difference wire size in 18- and 22-slot
edgewise appliances require a different approach
to mechanotherapy.
45. Moderate anchorage treatment with
18-slot edgewise
• Most commonly used wire 16x22 SS.
• Beta-Ti wire produce smaller force than SS.
• Either loop or sliding mechanics can be used.
• Single or narrow twin brackets on canine and
premolar is ideally for use of closing loops in
continuous arch wire.
46. • Closing loop in a horizontal direction rather
than vertical to prevent tipping.
• Greater retraction if 2nd molar is part of
anchorage &less if incisor torque is required.
• Delta-,L- or T- shaped loop is preferred.
• 17x 25 Beta-Ti wire used for finishing phase of
treatment.
Delta- loop T- loop
47. Moderate anchorage treatment with
22-slot edgewise
• Most commonly used wire 19x25 SS.
• 18x25 SS wire can be used.
• As a general rule,(60:40) it can be done in two
steps:
1st Retracting the canines usually with sliding
mechanics using Niti coil spring.
2nd Retracting the four incisors usually with
closing loop mechanics.
• En masse retraction as one step using opus or
T-loop.
48. Maximum anchorage treatment with
18-slot edgewise
• Most commonly used wire 16x22 SS.
• Friction from sliding mechanics should be
avoided and using closing loop mechanics is
better.
• To augment anchorage and reduce its strain by
doing the following:
1. Adding stabilizing lingual arch.
49. 2. Reinforce maxillary posterior anchorage with
extra oral force and if needed use Cl III elastics
from high pull headgear to supplement retraction
force in the lower arch.
3. Retraction of canines independently preferably
using a segmented closing loop and then retract
the incisors with a second closing loop arch wire.
50. 4. Use bone screws to stabilize the posterior
segment which used to avoid two steps space
closure.
51. Maximum anchorage treatment with
22-slot edgewise
• Most commonly used wire 19x25 SS.
• The same basic approaches are used with 18-
slot appliance.
• In sliding mechanics, a bone screw between
2nd molar and 1st molar is effective and easier
with a Niti coil spring.
• The recommended procedure in two-step
space closure, is en masse distal tipping of
anterior teeth followed by uprightening.
52. Minimum anchorage treatment
• Requires anchor control to reduce the incisal
retraction by the following:
1) Involving many teeth in the anterior anchor unit
as possible.
2) Extraction the most posterior teeth.
3) Reinforce the incisor anchorage by placing active
lingual root torque in the incisor section of arch
wire.
4) Break down the posterior anchorage by moving
the posterior teeth forward one tooth at a time.
53. 5)Use skeletal anchorage (bone screw) in either arch in
canine region to bring posterior teeth forward.
54. Retraction methods
A) Methods of canine retraction:
Sliding mechanics:
• Closed coil spring ( SS, Niti, Co-Cr-Ni)
• Elastomeric chains.
• Elastic module activated with ligature wire.
Loop mechanics:
• Gjessing retraction spring.
• Brustone T – loop.
• Delta loop.
• Omega loop.
• L – loop.
Extra oral: headgear. Gjessing retraction spring
55. B) Methods of en masse retraction of four incisors:
Sliding mechanics:
• Closed coil spring ( SS, Niti, Co-Cr-Ni)
• Elastomeric chains.
• Elastic module with ligature wire.
Loop mechanics:
• Brustone T – loop.
• Retraction utility arch.
• Delta loop.
• Omega loop.
• L – loop.
• Closing loop arch wire.
Extra oral: headgear.
56. C) Methods of en masse retraction of six incisors:
Sliding mechanics:
• Closed coil spring ( SS, Niti, Co-Cr-Ni)
• Elastomeric chains.
• Elastic module activated with ligature wire.
Loop mechanics:
• Closing loops.
• Brustone T – loop continuous arch wire.
• Opus loop (siatkowaski).
58. References
• Contemporary Orthodontic 5th edition – William
R. Proffit.
• Excellence in orthodontic 2010 – David Birnie,
Nigel Harradine.
• Biomechanics in clinical orthodontic – Ravindra
Nanda.
• Modern Edgewise mechanics and the segmented
arch technique – Dr.Charles J. Brustone.