The patient presented with Class II malocclusion, crowding, midline discrepancies, and rotated teeth. The proposed treatment plan is to use a modified twin block appliance for growth modification followed by fixed appliances to align and level the teeth, close extraction spaces, and achieve Class I canine and molar relationships. Upon completion of active treatment, fixed retainers will be placed in the upper and lower arches for long-term retention.
Smile analysis in vertical dimention:- factors to be considered when observed...Dr.Maulik patel
This is article description of smile when observing in vertical dimension ,maily used by dentist (orthodontist) while treatment of gummy smile with braces.
Intrusion in orthodontics /certified fixed orthodontic courses by Indian dent...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Common sense mechanics 4 /certified fixed orthodontic courses by Indian denta...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Common sense mechanics in orthodontics /certified fixed orthodontic courses b...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Space closure 2 /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Maxilla, Mandible & Hyoid Bone & Clinical Correlations by Dr. RIG.pptx
case presentation by Dr. jamal a. m. hafiz al qadhi
1. D O N E B Y : D R . J A M A L B I N H A F I Z
S U P E R V I S E D B Y : D R . A H M A D A L T A R A W N E H
D R . J U M A N A T B A I S H A T
D R . B A S H A R A L M O M A N I
D R . A N W A R A L R A H A M N E H
Orthodontic Case Presentation
3. Medical and Dental History
Medical History: Denied any medical problems
Dental History: Trauma 4 years ago on Upper Central and lateral
incisors with incisal filling on the Left central and
lateral incisors.
Habits: No Habits
4. Chief Complaint
“ العلوية أسنانيو بعض فوقطالعة
لبرا. ”
“ My upper teeth are
overlapped and
protruded.”
9. TMJ
Signs of TMD (No clicking, crepitus, but find
tenderness and pain to palpation).
Normal mouth opening.
Displacement. *
No Limitation in lateral movement.
14. Smile Aesthetics Assessment
Mini- estathetic
• 80% crown show when smiling
• No gingival show of the upper
gingiva.
• Smile extends to mesial surface
of first premolar on the right side,
and to distal surface of canine on
left side.
15. Smile Analysis
• Buccal corridors: narrow
• The smile arc: Incisal edges
of upper anterior teeth are
not parallel to the upper
border of the lower lip
• Flat smile arc.
• Less attractive smile.
16. Tooth Proportions
Micro – esthetic:
Golden proportion for maxillary
anterior teeth is 55%
Height:width
1:9 90%
22. Upper Arch
U-shaped arch.
Anterior segment:
Rotated upper incisors with
mild crowding .
Upper left canine palatally
tilted.
Normal Buccal segment
23. Anterior Segment Relationship
Class II div. I incisor relationship
Midlines discrepancy; lower shifted 3mm to Rt. And
upper shifted 1mm to Lt.
• Overjet = 6.5 mm
Overbite = 40% Complete on teeth
24. Buccal Segment Relationship
Molar relationship: R: Class II L: Class I
Canine relationship: R: Class II L: Class I
Scissor bite in Lt.4&5
44. Panoramic Radiograph
All teeth are present including all 8’s
Right side ramus length = 69.1
Left side ramus length =69.3
45. Diagnostic Summary
R.K is a 14 year old female, denied any relevant medical problem and multiple
dental fillings with fair oral hygiene, complains of “My upper teeth are
protruding and overlapping”.
She has a class II/I incisor relationship based on class II skeletal pattern,
average lower facial height, incompetent lips, and a mildly convex facial
profile, acute labiomental and nasolabial angles with slight facial asymmetry.
Cant of maxilla ,O.J of 6.5 mm, O.B average complete to the teeth, mild
crowded upper arch. Upper midline shift to the left 1 mm and lower midline
shift to the right 3 mm. Scissor bite on the lower left 4,5. Molar relationship is
class I on the left side and class II on the right side, canine relationships is
class I on the left side and class II on the right side.
Complicated by lower dental displacement to the right, Proclined lower labial
segment, Rotated upper left 1,2 and right 2, lower right 5. Lingualy tilted lower
left 4,5, Deep curve of spee in the lower Lt. side, and anterior Bolton
discrepancy .
46. Problem List…
Pathological:
Gingivitis and plaque deposition, white spot lesion on upper Rt. 5
C/C “Protruding and overlapping my upper teeth”
Skeletal:
Class II skeletal pattern
Soft tissue:
Slight facial asymmetry
Incompetent lips
Convex facial profile
Acute labiomental and nasolabial angles
47. Problem List
Dental:
Cant of maxilla
Class II div. I incisor relationship
Overjet 6.5 mm.
Scissor bite on the lower left side 4,5,.
Displacement of lower arch.
Upper midline shift to the left 1 mm and lower midline shift to the right
3mm
Lower incisor proclined
Lingually tilted lower left 4,5
Rotated upper left 1,2, right 2 and lower right 5
Class II full unit molar and canine on the Rt.side.
Mild upper arch crowding
Deep curve of spee on the lower left side of arch.
Anterior bolton discrepancy
48. Treatment Aims
Improve oral hygiene.
Address c/c of the patient’s
Skeletal:
Accept mild class II SK pattern
Correct maxilla cant.
Soft tissue:
Accept Slight facial soft tissue
asymmetry
Achieve competent lips
Accept convex profile
Correct labiomental and nasolabial
angles
Dental:
correct dentoalveoular Cant of maxilla
Achieve class I incisor relation.
Correct Over jet.
Correct scissor bite and displacement .
Correct rotated teeth.
Correct mild crowding in upper.
Correct upper and lower midline shift.
Correct inclination of lower anterior segment.
Achieve class I canine in the Rt. Side and
maintain class I in the Lt. side.
Achieve class II molar in left side and
minatine class II in the Rt. Side.
Level curve of spee.
Correct Bolton discrepancy.
Maintain the correct result.
49. Treatment Plan
(GROWTH MODIFICATION)
(Hybrid Appliance)
1. OHI.
2. Modified Twin block appliance(Hybrid Appliance).
3. Upper and lower fixed app.
4. Re-evaluation for Extraction pattern.
5. Retention:
Long term: Upper and lower fixed retainer from 3-3 &(SCF )
Short term: Upper and Lower H.R
50. Justification (Extraction)
DENTAL:
CRITERIA VALUE NORMAL V. PRO/CON
Tooth size- arch length Upper : -3.5 mm
Lower: +1
8-11 mm crowding CON. Ext
Curve of Spee L:3mm,R:1mm More than 6 severe CON. Ext
Bolton discrepancy 85% If 4* more then extract CON. Ext
Peck & Peck L1:80%
L2: 75%
L1:88-92 (if less extract)
L2: 90-95 (if less
extract)
PRO. Ext
PRO. Ext
Irregularity index 0 mm X>6.5 mm extract CON. Ext
Incisor-Man. Plane angle 105˚ 85˚-95˚ PRO. Ext
Frankfurt-Man. Incisal angle 55 60˚-75˚ PRO. Ext
Upper incisor to NA 6mm, 27.5˚ 4mm anterior, (22-25) PRO. Ext
Lower incisor to NB 7 mm, 37˚ 4 mm anterior ( 22-25) PRO. Ext
Lower incisor to A-pog 4 1-3 mm anterior to it PRO. Ext
52. Justification (Extraction)
SOFT TISSUE
CRITERIA VALUE NORMAL VALUE PRO/CON
NON-EXTRACTION
POSITION OF
UPPER LIP –E LINE
3.5mm 2mm ±3 CON. Ext
POSITION OF
LOWER LIP- E LINE
2 mm 2mm ±3 CON. Ext
NASOLABIAL
ANGLE
85 90˚-115˚ PRO. Ext
UPPER LIP
MORPHOLOGY
12mm≠
15mm
(strained)
3 mm belowe sk A
point =
Vermilion to labial
surface of teeth ±1
PRO. Ext.
53. Justification
OTHER FACTORS
CRITERIA VALUE PRO/CON NON-EXTRACTION
GROWTH Non growing patient PRO. Ext
MIDLINE In-coincident PRO. Ext
PATIENT PEREFERENCE Extraction PRO. Ext
54. Justification
Growth Modification: (Modified twine block)
Mild Skeletal class II.
Cant maxilla
Dentoalveoular effect
Fixed Appliance
Alignment and leveling of teeth
3-D tooth movement( bodily movement)
Closing of spaces and retraction of anterior
teeth
Upper and lower arch coordination
MBT prescription slot 0.022:
High torque is needed to retract the
anterior teeth
Less anchorage demand.
55. Justification
Retention:
Upper fixed retainer: crowding ,rotation and midline
shift.
Upper CSF: rotated incisors
Upper H.R: to prevent re opening Ext. space and
improve settling.
Lower H.R.: stabilize dental arch and improve
settling.
Lower fixed retainer: prevent late anterior mandibular
crowding and midline shift.
56. Treatment Details and Mechanics
1. Full records
2. Impression for modified twin block
3. Delivery of modified twin block(wear full time)
After we get true molar and canine relationship
by dentoalveoular effect:
11. Separators on upper and lower 6’s
12. Band selection and cementation on upper and lowe
6’s
13. Upper and lower direct bonding of fixed appliance
MBT slot 22.
57. Treatment Details and Mechanics
15. Aligning and leveling upper and lower arch using wires
0.014, 0.018 and 0.017*0.025 NiTi
16. Working upper wire 0.019*0.025 SS (expanded)
17. Re-evaluat for extraction pattern
18. Retraction of upper anterior teeth into class 1 by close
coil spring.
20. Steel ligation from 3-3 in the upper arch.
21. Close remaining space from post- anterior.
22. Interproximal reduction of lower ant. teeth and
reshaping of upper incisors.
23. Finishing and detailing using 0.021*0.025 TMA wire
58. Treatment Details and Mechanics
25. settling .
26. Retention:
Upper and lower fixed retention from 3-3 using
multistranded 17.5 mil SS.
Debonding of upper and lower fixed app.
Upper impression for upper and lowerH.R.
26. Insertion of upper and lower H.R.
Upper and lower impressions for constructing then delivery of modified oral screen (wear at night and 2-3 hours during the day)
(wear for 3 months and maintain for another 3 months)