This document discusses various methods for space closure during orthodontic treatment. It begins by stating that space closure is dictated by treatment objectives and can be achieved through different mechanisms. The goals for any space closure method are then outlined, including differential tooth movement control and producing an optimal biological response. Key determinants of space closure like the amount of crowding, anchorage, and tooth inclinations are also discussed. The document then goes on to compare sliding/friction mechanics versus loop/frictionless mechanics. It provides details on considerations for various anchorage situations and techniques for individual canine retraction. In summary, the document provides an overview of factors to consider for space closure and compares different mechanical approaches.